Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea.

scientific article

Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.8636
P932PMC publication ID5173047
P698PubMed publication ID27070092

P50authorHaibo ShiQ50432378
Phillip I. BirdQ50638386
P2093author name stringYan Chen
Muhammad Waqas
Lei Wang
Huawei Li
Xiaoli Zhang
Shasha Zhang
Mingliang Tang
Renjie Chai
Luo Guo
P2860cites workMammalian cochlear supporting cells can divide and trans-differentiate into hair cellsQ22251095
Wnt activation protects against neomycin-induced hair cell damage in the mouse cochleaQ27328992
Identification of stem cells in small intestine and colon by marker gene Lgr5Q28131701
Wnt5a functions in planar cell polarity regulation in miceQ28505898
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of CortiQ28507372
Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathwayQ28507459
Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22.Q28512415
Math1: an essential gene for the generation of inner ear hair cellsQ28513764
Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox geneQ28584712
Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochleaQ41820010
MRNA expression of members of the IGF system in the organ of Corti, the modiolus and the stria vascularis of newborn ratsQ42452384
Expression and immunohistochemical localization of TMEM16A/anoctamin 1, a calcium-activated chloride channel in the mouse cochleaQ42491896
KCNJ10 (Kir4.1) potassium channel knockout abolishes endocochlear potentialQ42515610
Notch signaling regulates the extent of hair cell regeneration in the zebrafish lateral line.Q46729652
Bmi1 Regulates the Proliferation of Cochlear Supporting Cells Via the Canonical Wnt Signaling PathwayQ50317124
Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas.Q50469470
Accumulation of hypoxia-inducible factor-1alpha in mouse inner ear by noise stimulation.Q50475514
Pluripotent stem cells from the adult mouse inner ear.Q50482567
Regeneration of sensory hair cells after acoustic trauma.Q50563884
Neuropeptide Y in rat spiral ganglion neurons and inner hair cells of organ of corti and effects of a nontraumatic acoustic stimulation.Q51811252
Dynamic expression of COUP-TFI and COUP-TFII during development and functional maturation of the mouse inner ear.Q52049244
Pattern of expression of the jun family of transcription factors during the early development of the inner ear: implications in apoptosis.Q52173415
Dll3 is expressed in developing hair cells in the mammalian cochleaQ81154349
Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner earQ28585081
The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survivalQ28586935
A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouseQ28587795
Foxg1 is required for morphogenesis and histogenesis of the mammalian inner earQ28589083
Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cellsQ28591413
Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner earQ28592816
Characterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factorQ28650122
STRING v9.1: protein-protein interaction networks, with increased coverage and integrationQ29614691
A robust and high-throughput Cre reporting and characterization system for the whole mouse brainQ29616609
In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1Q30392749
Lgr5+ cells regenerate hair cells via proliferation and direct transdifferentiation in damaged neonatal mouse utricleQ30401408
Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivoQ30408063
Regulated reprogramming in the regeneration of sensory receptor cells.Q30414064
Regulation of the orphan nuclear receptor Nr2f2 by the DFNA15 deafness gene Pou4f3.Q30426367
Lgr5-positive supporting cells generate new hair cells in the postnatal cochleaQ30441281
Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitorsQ30442841
Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells.Q30449308
Regenerated hair cells can originate from supporting cell progeny: evidence from phototoxicity and laser ablation experiments in the lateral line systemQ30456826
Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochleaQ30460671
Intrinsic regenerative potential of murine cochlear supporting cells.Q30472028
Sox2 and JAGGED1 expression in normal and drug-damaged adult mouse inner ear.Q30490970
Manipulating cell cycle regulation in the mature cochleaQ30493183
Dynamic expression of Lgr6 in the developing and mature mouse cochleaQ30650047
Exploration of the cell-cycle genes found within the RIKEN FANTOM2 data set.Q30805626
Characterization of transcriptomes of cochlear inner and outer hair cellsQ34037606
Cell type-specific transcriptome analysis reveals a major role for Zeb1 and miR-200b in mouse inner ear morphogenesisQ34042739
HMGA2, the architectural transcription factor high mobility group, is expressed in the developing and mature mouse cochleaQ35097530
Gene Expression by Mouse Inner Ear Hair Cells during DevelopmentQ35515541
The BCL-2 family reunionQ35568029
Wnt-responsive Lgr5-expressing stem cells are hair cell progenitors in the cochleaQ36160283
Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivoQ36336938
Sensory regeneration in the vertebrate inner ear: differences at the levels of cells and speciesQ37757414
Antisense oligonucleotide to NOR-1, a novel orphan nuclear receptor, induces migration and neurite extension of cultured forebrain cellsQ38363433
Cadherin 23 is a component of the tip link in hair-cell stereociliaQ40571247
XIRP2, an actin-binding protein essential for inner ear hair-cell stereociliaQ41220564
Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner earsQ41736617
P4510describes a project that usesImageJQ1659584
P433issue27
P407language of work or nameEnglishQ1860
P304page(s)41123-41141
P577publication date2016-07-01
P1433published inOncotargetQ1573155
P1476titleCharacterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea
P478volume7

Reverse relations

cites work (P2860)
Q91612466Age-related transcriptome changes in Sox2+ supporting cells in the mouse cochlea
Q47716290Autophagy protects auditory hair cells against neomycin-induced damage.
Q33869949Characterization of Lgr5+ Progenitor Cell Transcriptomes after Neomycin Injury in the Neonatal Mouse Cochlea
Q55362003Characterization of Lgr6+ Cells as an Enriched Population of Hair Cell Progenitors Compared to Lgr5+ Cells for Hair Cell Generation in the Neonatal Mouse Cochlea.
Q30356896Characterization of the Transcriptomes of Lgr5+ Hair Cell Progenitors and Lgr5- Supporting Cells in the Mouse Cochlea.
Q28596069Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles
Q39094885Concise Review: Regeneration in Mammalian Cochlea Hair Cells: Help from Supporting Cells Transdifferentiation
Q48106637Extensive Supporting Cell Proliferation and Mitotic Hair Cell Generation by In Vivo Genetic Reprogramming in the Neonatal Mouse Cochlea.
Q92711491Frizzled-9+ Supporting Cells Are Progenitors for the Generation of Hair Cells in the Postnatal Mouse Cochlea
Q47192519Hedgehog Signaling Promotes the Proliferation and Subsequent Hair Cell Formation of Progenitor Cells in the Neonatal Mouse Cochlea
Q37687045Inhibition of ARC decreases the survival of HEI-OC-1 cells after neomycin damage in vitro
Q55017430Junctional E-cadherin/p120-catenin Is Correlated with the Absence of Supporting Cells to Hair Cells Conversion in Postnatal Mice Cochleae.
Q93111529Knockdown of Foxg1 in supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse cochlea
Q27319552LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea
Q30365175Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse Reformation
Q91632636Multiple supporting cell subtypes are capable of spontaneous hair cell regeneration in the neonatal mouse cochlea
Q64930524Novel compounds protect auditory hair cells against gentamycin-induced apoptosis by maintaining the expression level of H3K4me2.
Q38836733Regeneration of hair cells in the mammalian vestibular system
Q30360502Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea.
Q30835814c-Myb knockdown increases the neomycin-induced damage to hair-cell-like HEI-OC1 cells in vitro

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