| scholarly article | Q13442814 |
| P50 | author | Konrad Hochedlinger | Q40635003 |
| P2093 | author name string | Albert S B Edge | |
| Fuxin Shi | |||
| Katrin Arnold | |||
| Naomi F Bramhall | |||
| P2860 | cites work | Notch signalling pathway mediates hair cell development in mammalian cochlea | Q22009040 |
| Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells | Q22251095 | ||
| Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling | Q24310750 | ||
| Essential role of retinoblastoma protein in mammalian hair cell development and hearing | Q24545148 | ||
| Identification of stem cells in small intestine and colon by marker gene Lgr5 | Q28131701 | ||
| Prestin is the motor protein of cochlear outer hair cells | Q28144919 | ||
| Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate | Q28200195 | ||
| Delta1 expression, cell cycle exit, and commitment to a specific secretory fate coincide within a few hours in the mouse intestinal stem cell system | Q28507332 | ||
| Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti | Q28507372 | ||
| Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti | Q28508562 | ||
| Disruption of fibroblast growth factor receptor 3 signaling results in defects in cellular differentiation, neuronal patterning, and hearing impairment | Q28511525 | ||
| Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells | Q28511693 | ||
| Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development | Q28513519 | ||
| Notch signaling regulates the pattern of auditory hair cell differentiation in mammals | Q28577942 | ||
| Wnt signalling induces maturation of Paneth cells in intestinal crypts | Q28593773 | ||
| Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells | Q29614268 | ||
| A global double-fluorescent Cre reporter mouse | Q29616157 | ||
| A robust and high-throughput Cre reporting and characterization system for the whole mouse brain | Q29616609 | ||
| Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors | Q30442841 | ||
| Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma | Q30444617 | ||
| Regenerated hair cells can originate from supporting cell progeny: evidence from phototoxicity and laser ablation experiments in the lateral line system | Q30456826 | ||
| Regenerative proliferation in inner ear sensory epithelia from adult guinea pigs and humans | Q30467645 | ||
| Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles | Q30468270 | ||
| Regenerative proliferation in organ cultures of the avian cochlea: identification of the initial progenitors and determination of the latency of the proliferative response. | Q30468882 | ||
| Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea | Q30481816 | ||
| Expression of Prox1 during mouse cochlear development | Q30492966 | ||
| Beta-catenin up-regulates Atoh1 expression in neural progenitor cells by interaction with an Atoh1 3' enhancer | Q33581311 | ||
| Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice | Q34222321 | ||
| Wnt-responsive Lgr5-expressing stem cells are hair cell progenitors in the cochlea | Q36160283 | ||
| Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium | Q36444132 | ||
| Notch in the intestine: regulation of homeostasis and pathogenesis. | Q38063299 | ||
| Temporal, spatial, and morphologic features of hair cell regeneration in the avian basilar papilla | Q42483231 | ||
| Notch signaling imparts and preserves neural stem characteristics in the adult brain | Q42827654 | ||
| FGFR3 expression during development and regeneration of the chick inner ear sensory epithelia. | Q43849600 | ||
| Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas. | Q50469470 | ||
| Evidence for supporting cell mitosis in response to acoustic trauma in the avian inner ear | Q50536537 | ||
| Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea. | Q51980744 | ||
| The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. | Q52040186 | ||
| Ultrastructural evidence for hair cell regeneration in the mammalian inner ear | Q70619029 | ||
| Identification of the timing of S phase and the patterns of cell proliferation during hair cell regeneration in the chick cochlea | Q72001365 | ||
| Mammalian vestibular hair cell regeneration | Q72485240 | ||
| Multiple roles of Notch signaling in cochlear development | Q80390441 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 3 | |
| P304 | page(s) | 311-322 | |
| P577 | publication date | 2014-02-20 | |
| P1433 | published in | Stem Cell Reports | Q27725039 |
| P1476 | title | Lgr5-positive supporting cells generate new hair cells in the postnatal cochlea | |
| P478 | volume | 2 |
| Q64963214 | A Critical E-box in Barhl1 3' Enhancer Is Essential for Auditory Hair Cell Differentiation. |
| Q30362142 | A central to peripheral progression of cell cycle exit and hair cell differentiation in the developing mouse cristae. |
| Q50300953 | A mouse model of miR-96, miR-182 and miR-183 misexpression implicates miRNAs in cochlear cell fate and homeostasis. |
| Q34550656 | A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear |
| Q92709377 | AAV-ie enables safe and efficient gene transfer to inner ear cells |
| Q90233339 | Activation of the RhoA-YAP-β-catenin signaling axis promotes the expansion of inner ear progenitor cells in 3D culture |
| Q64238788 | Applications of Lgr5-Positive Cochlear Progenitors (LCPs) to the Study of Hair Cell Differentiation |
| Q38342851 | Atoh1 gene therapy in the cochlea for hair cell regeneration |
| Q64257520 | Atoh1 regulation in the cochlea: more than just transcription |
| Q50317124 | Bmi1 Regulates the Proliferation of Cochlear Supporting Cells Via the Canonical Wnt Signaling Pathway |
| Q27303985 | Cell cycle reactivation of cochlear progenitor cells in neonatal FUCCI mice by a GSK3 small molecule inhibitor |
| Q96303149 | Cell-Specific Transcriptional Responses to Heat Shock in the Mouse Utricle Epithelium |
| Q57486541 | Cell-Specific Transcriptome Analysis Shows That Adult Pillar and Deiters' Cells Express Genes Encoding Machinery for Specializations of Cochlear Hair Cells |
| Q30414390 | Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea |
| Q54234621 | Characterization of Hair Cell-Like Cells Converted From Supporting Cells After Notch Inhibition in Cultures of the Organ of Corti From Neonatal Gerbils. |
| Q33869949 | Characterization of Lgr5+ Progenitor Cell Transcriptomes after Neomycin Injury in the Neonatal Mouse Cochlea |
| Q30367432 | Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea. |
| Q100946134 | Characterization of rare spindle and root cell transcriptional profiles in the stria vascularis of the adult mouse cochlea |
| Q30356896 | Characterization of the Transcriptomes of Lgr5+ Hair Cell Progenitors and Lgr5- Supporting Cells in the Mouse Cochlea. |
| Q90641949 | Characterization of the transcriptomes of Atoh1-induced hair cells in the mouse cochlea |
| Q30358444 | Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells |
| Q28596069 | Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles |
| Q39062528 | Cochlear hair cell regeneration after noise-induced hearing loss: Does regeneration follow development? |
| Q92130780 | Cochlear supporting cells function as macrophage-like cells and protect audiosensory receptor hair cells from pathogens |
| Q104135023 | Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea |
| Q39472745 | Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development |
| Q30361676 | Diphtheria Toxin-Induced Cell Death Triggers Wnt-Dependent Hair Cell Regeneration in Neonatal Mice |
| Q90748537 | Direct cellular reprogramming and inner ear regeneration |
| Q37043874 | Distinct Expression Pattern of a Deafness Gene, KIAA1199, in a Primate Cochlea |
| Q46460297 | Distinct capacity for differentiation to inner ear cell types by progenitor cells of the cochlea and vestibular organs |
| Q36245117 | Epigenetic regulation of Atoh1 guides hair cell development in the mammalian cochlea |
| Q48106637 | Extensive Supporting Cell Proliferation and Mitotic Hair Cell Generation by In Vivo Genetic Reprogramming in the Neonatal Mouse Cochlea. |
| Q92711491 | Frizzled-9+ Supporting Cells Are Progenitors for the Generation of Hair Cells in the Postnatal Mouse Cochlea |
| Q92382361 | Generation of new hair cells by DNA methyltransferase (Dnmt) inhibitor 5-azacytidine in a chemically-deafened mouse model |
| Q36258549 | Hair Cell Loss, Spiral Ganglion Degeneration, and Progressive Sensorineural Hearing Loss in Mice with Targeted Deletion of Slc44a2/Ctl2. |
| Q30414203 | Hair cell damage recruited Lgr5-expressing cells are hair cell progenitors in neonatal mouse utricle |
| Q67471784 | High-resolution transcriptional dissection of in vivo Atoh1-mediated hair cell conversion in mature cochleae identifies Isl1 as a co-reprogramming factor. |
| Q30355338 | Identification of mouse cochlear progenitors that develop hair and supporting cells in the organ of Corti |
| Q30392749 | In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1 |
| Q33906465 | Inactivation of STAT3 Signaling Impairs Hair Cell Differentiation in the Developing Mouse Cochlea |
| Q39005768 | Insights into inner ear-specific gene regulation: Epigenetics and non-coding RNAs in inner ear development and regeneration |
| Q93111529 | Knockdown of Foxg1 in supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse cochlea |
| Q27319552 | LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea |
| Q30415959 | Making sense of Wnt signaling-linking hair cell regeneration to development |
| Q30390034 | Manipulating cell fate in the cochlea: a feasible therapy for hearing loss |
| Q100525834 | Mechanical forces drive ordered patterning of hair cells in the mammalian inner ear |
| Q27316536 | MiR-210 promotes sensory hair cell formation in the organ of corti |
| Q91632636 | Multiple supporting cell subtypes are capable of spontaneous hair cell regeneration in the neonatal mouse cochlea |
| Q38384722 | New treatment options for hearing loss. |
| Q28507459 | Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway |
| Q47727741 | Preservation of Cells of the Organ of Corti and Innervating Dendritic Processes Following Cochlear Implantation in the Human: an Immunohistochemical Study |
| Q39165751 | Quantitative Analysis of Supporting Cell Subtype Labeling Among CreER Lines in the Neonatal Mouse Cochlea |
| Q41170353 | Recent Advancements in the Regeneration of Auditory Hair Cells and Hearing Restoration |
| Q39010893 | Recent advances in therapeutics and drug delivery for the treatment of inner ear diseases: a patent review (2011-2015). |
| Q38836733 | Regeneration of hair cells in the mammalian vestibular system |
| Q38856378 | Regeneration of pancreatic insulin-producing cells by in situ adaptive cell conversion |
| Q90996747 | Repair Schwann cell update: Adaptive reprogramming, EMT, and stemness in regenerating nerves |
| Q38928250 | Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea |
| Q33826051 | SOX2 is required for inner ear neurogenesis |
| Q27004338 | Sensory hair cell development and regeneration: similarities and differences |
| Q39015106 | Signaling in the Auditory System: Implications in Hair Cell Regeneration and Hearing Function |
| Q30432254 | Sound strategies for hearing restoration. |
| Q52725769 | Sox2 haploinsufficiency primes regeneration and Wnt responsiveness in the mouse cochlea. |
| Q36700267 | Sox2 in the differentiation of cochlear progenitor cells |
| Q30408338 | Sox2-CreER mice are useful for fate mapping of mature, but not neonatal, cochlear supporting cells in hair cell regeneration studies |
| Q30398509 | SoxC transcription factors are essential for the development of the inner ear |
| Q55311521 | Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells. |
| Q30411022 | Spontaneous regeneration of cochlear supporting cells after neonatal ablation ensures hearing in the adult mouse |
| Q30360264 | Supernumerary human hair cells-signs of regeneration or impaired development? A field emission scanning electron microscopy study |
| Q30397535 | The Role of Atonal Factors in Mechanosensory Cell Specification and Function |
| Q38287418 | The Stem Cell Marker Lgr5 Defines a Subset of Post-Mitotic Neurons in the Olfactory Bulb. |
| Q93080637 | Therapeutic Potential of Wnt and Notch Signaling and Epigenetic Regulation in Mammalian Sensory Hair Cell Regeneration |
| Q57285571 | Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1 |
| Q58616047 | Transcriptional response to Wnt activation regulates the regenerative capacity of the mammalian cochlea |
| Q30367587 | Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing. |
| Q64081101 | Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1 |
| Q92030493 | Ultrastructural Characterization of Stem Cell-Derived Replacement Vestibular Hair Cells Within Ototoxin-Damaged Rat Utricle Explants |
| Q88541625 | Understanding Molecular Evolution and Development of the Organ of Corti Can Provide Clues for Hearing Restoration |
| Q30360502 | Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea. |
| Q39319057 | Wnt/β-catenin signaling in adult mammalian epithelial stem cells |
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