Biological synthesis of circular polypeptides

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Biological synthesis of circular polypeptides is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.R111.305508
P932PMC publication ID3411040
P698PubMed publication ID22707722
P5875ResearchGate publication ID227179348

P2093author name stringJulio A Camarero
Teshome L Aboye
P2860cites workAmino and carboxy-terminal regions in globular proteinsQ21045397
"Splicing up" drug discovery. Cell-based expression and screening of genetically-encoded libraries of backbone-cyclized polypeptidesQ24634502
Enzymatic cyclization of a potent bowman-birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptideQ27640635
Chemistry. Seamless proteins tie up their loose endsQ28302533
Peptide chemical ligation inside living cells: in vivo generation of a circular protein domain.Q30167926
Rescuing a destabilized protein fold through backbone cyclizationQ30168182
Expressed protein ligation: a resourceful tool to study protein structure and function.Q30379910
Protein synthesis by native chemical ligation: expanded scope by using straightforward methodologyQ30761992
Sortase A as a novel molecular "stapler" for sequence-specific protein conjugation.Q50697019
Circular β-lactamase: stability enhancement by cyclizing the backboneQ57840029
Chemical ligation of unprotected peptides directly from a solid supportQ74481443
Flexizymes for genetic code reprogrammingQ84261526
Chemical Synthesis of a Circular Protein Domain: Evidence for Folding-Assisted CyclizationQ88519997
Production of cyclic peptides and proteins in vivoQ30816360
Diverse backbone-cyclized peptides via codon reprogrammingQ30885740
Expressed protein ligation: a new tool for the biosynthesis of cyclic polypeptidesQ33227729
Split-intein mediated circular ligation used in the synthesis of cyclic peptide libraries in E. coli.Q33286530
Biosynthesis of circular proteins in plantsQ33310757
Biosynthesis and biological screening of a genetically encoded library based on the cyclotide MCoTI-I.Q33506664
Intein-mediated cyclization of randomized peptides in the periplasm of Escherichia coli and their extracellular secretionQ33596289
Cyclotides, a promising molecular scaffold for peptide-based therapeuticsQ33610239
Evolution of cyclic peptide protease inhibitorsQ33937777
Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptidesQ34004482
Synthesis of native proteins by chemical ligationQ34019420
Topology, stability, sequence, and length: defining the determinants of two-state protein folding kineticsQ34031904
Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.Q34048086
In vivo biosynthesis of an Ala-scan library based on the cyclic peptide SFTI-1Q34115228
Backbone dynamics of cyclotide MCoTI-I free and complexed with trypsin.Q34152482
Recombinant production of rhesus θ-defensin-1 (RTD-1) using a bacterial expression system.Q34156786
Semisynthesis of proteins by expressed protein ligationQ34531980
Sortase-catalyzed transformations that improve the properties of cytokinesQ34602642
Biosynthesis and antimicrobial evaluation of backbone-cyclized α-defensinsQ35610217
Mapping structural interactions using in-cell NMR spectroscopy (STINT-NMR).Q35660031
Biological Activities of Natural and Engineered Cyclotides, a Novel Molecular Scaffold for Peptide-Based TherapeuticsQ35893500
Synthesis of biopolymers using genetic code reprogrammingQ37076816
Two-hybrid technologies in proteomics researchQ37213399
A straight path to circular proteinsQ37257416
Sortase-mediated ligation: a gift from Gram-positive bacteria to protein engineering.Q37387169
Discovery, structure and biological activities of cyclotides.Q37496224
Cyclotides as templates in drug designQ37624969
Cyclization of conotoxins to improve their biopharmaceutical properties.Q37819305
Contemporary strategies for peptide macrocyclizationQ37893450
Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways.Q38740325
Sortase A as a tool for high-yield histatin cyclizationQ39551799
Albumins and their processing machinery are hijacked for cyclic peptides in sunflowerQ43418019
Cyclic green fluorescent protein produced in vivo using an artificially split PI-PfuI intein from Pyrococcus furiosus.Q43560102
Biosynthesis of a fully functional cyclotide inside living bacterial cells.Q45999380
Biosynthesis of the cyclotide Kalata B1 by using protein splicingQ46808548
Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides.Q47797295
P433issue32
P407language of work or nameEnglishQ1860
P304page(s)27026-27032
P577publication date2012-06-14
P1433published inJournal of Biological ChemistryQ867727
P1476titleBiological synthesis of circular polypeptides
P478volume287

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cites work (P2860)
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Q34069909Asteropsins B-D, sponge-derived knottins with potential utility as a novel scaffold for oral peptide drugs
Q28244237Butelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesis
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Q45216335Chemical bypass of intein-catalyzed N-S acyl shift in protein splicing
Q47224864Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta
Q28534321Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism
Q39330201Cyclotides: Overview and Biotechnological Applications
Q36017639Efficient recombinant expression of SFTI-1 in bacterial cells using intein-mediated protein trans-splicing
Q36748943Enhanced thermal stability of lichenase from Bacillus subtilis 168 by SpyTag/SpyCatcher-mediated spontaneous cyclization
Q35213008Enzyme-catalyzed macrocyclization of long unprotected peptides.
Q37157185Expression of fluorescent cyclotides using protein trans-splicing for easy monitoring of cyclotide-protein interactions
Q53472466Folding Construction of a Pentacyclic Quadruply fused Polymer Topology with Tailored kyklo-Telechelic Precursors.
Q27679062In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide
Q46125758In-cell production of a genetically-encoded library based on the θ-defensin RTD-1 using a bacterial expression system
Q33652036Intein applications: from protein purification and labeling to metabolic control methods
Q55397859Inteins: Localized Distribution, Gene Regulation, and Protein Engineering for Biological Applications.
Q38112084Joseph Rudinger memorial lecture: discovery and applications of cyclotides
Q39464000Making ends meet: chemically mediated circularization of recombinant proteins
Q38115259Patchwork protein chemistry: a practitioner's treatise on the advances in synthetic peptide stitchery
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Q37580653Recent advances in in vivo applications of intein-mediated protein splicing
Q34871830Recombinant expression of backbone-cyclized polypeptides
Q35285779Rheology of peptide- and protein-based physical hydrogels: are everyday measurements just scratching the surface?
Q35620228Ribosomal Synthesis of Macrocyclic Peptides in Vitro and in Vivo Mediated by Genetically Encoded Aminothiol Unnatural Amino Acids
Q41860085Secretion of circular proteins using sortase
Q27681346Semienzymatic Cyclization of Disulfide-rich Peptides Using Sortase A
Q33780021Sortase A-mediated crosslinked short-chain dehydrogenases/reductases as novel biocatalysts with improved thermostability and catalytic efficiency
Q90208426The Potential of the Cyclotide Scaffold for Drug Development
Q33731096Topology Engineering of Proteins in Vivo Using Genetically Encoded, Mechanically Interlocking SpyX Modules for Enhanced Stability

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