SAMP1/YitFc mouse strain: a spontaneous model of Crohn's disease-like ileitis

scientific article

SAMP1/YitFc mouse strain: a spontaneous model of Crohn's disease-like ileitis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1002/IBD.21638
P932PMC publication ID3154989
P698PubMed publication ID21557393
P5875ResearchGate publication ID51112522

P2093author name stringKlaus Ley
Giorgos Bamias
Fabio Cominelli
Kristen O Arseneau
Theresa T Pizarro
Brian K Reuter
Joseph R Mercado
Luca Pastorelli
Marcello Chieppa
Rekha R Garg
P2860cites workA frameshift mutation in NOD2 associated with susceptibility to Crohn's diseaseQ22251291
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel diseaseQ22252318
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokinesQ24294720
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDLQ24311741
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesisQ24656576
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's diseaseQ27860821
The organization, promoter analysis, and expression of the human PPARgamma geneQ28244071
Functional variants of OCTN cation transporter genes are associated with Crohn diseaseQ28258410
Genetic variation in DLG5 is associated with inflammatory bowel diseaseQ28258422
A genome-wide association study identifies IL23R as an inflammatory bowel disease geneQ28270603
Elevated expression of Paneth cell CRS4C in ileitis-prone SAMP1/YitFc mice: regional distribution, subcellular localization, and mechanism of actionQ28590753
Interleukin-10-deficient mice develop chronic enterocolitisQ29547881
Spontaneous development of inflammatory bowel disease in T cell receptor mutant miceQ72233696
Intestinal permeability test as a predictor of clinical course in Crohn's diseaseQ73081946
IL-4 exacerbates disease in a Th1 cell transfer model of colitisQ73401136
T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cellsQ74082060
Preventive effects of Bifidobacterium- and Lactobacillus-fermented milk on the development of inflammatory bowel disease in senescence-accelerated mouse P1/Yit strain miceQ77089238
Identification of a chemokine network that recruits FoxP3(+) regulatory T cells into chronically inflamed intestineQ79835752
Maturation of the mucosal immune system underlies colitis susceptibility in interleukin-10-deficient (IL-10-/-) miceQ80211025
Association between IL-18 gene promoter polymorphisms and inflammatory bowel disease in a Japanese populationQ81527817
-137 (G/C) IL-18 promoter polymorphism in patients with inflammatory bowel diseaseQ81550402
Probiotic Lactobacillus-induced improvement in murine chronic inflammatory bowel disease is associated with the down-regulation of pro-inflammatory cytokines in lamina propria mononuclear cellsQ81809212
Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel diseaseQ82257596
Epithelial NEMO links innate immunity to chronic intestinal inflammationQ59091394
VSL#3 Probiotic-Mixture Induces Remission in Patients with Active Ulcerative ColitisQ59120549
Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12Q59418582
Genetic analysis in Finnish families with inflammatory bowel disease supports linkage to chromosome 3p21Q60475357
Distinct cytokine patterns in early and chronic ileal lesions of Crohn's diseaseQ62660272
Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich ElementsQ62819809
Evidence for an inflammatory bowel disease locus on chromosome 3p26: linkage, transmission/disequilibrium and partitioning of linkageQ64461862
Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factorQ69656337
A new murine model of accelerated senescenceQ71011567
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1Q29614873
Inflammatory bowel diseaseQ29616286
IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cellsQ30304035
Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's diseaseQ30307038
Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in miceQ30308331
Down-regulation of intestinal lymphocyte activation and Th1 cytokine production by antibiotic therapy in a murine model of Crohn's diseaseQ30310154
Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitisQ30310728
Mouse models for the study of Crohn's diseaseQ30310867
TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosisQ30310991
Identification of a quantitative trait locus for ileitis in a spontaneous mouse model of Crohn's disease: SAMP1/YitFcQ30311093
Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel diseaseQ30311921
Beta7 integrin deficiency suppresses B cell homing and attenuates chronic ileitis in SAMP1/YitFc miceQ30429486
Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn diseaseQ30434096
Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritisQ30434426
Linkage to peroxisome proliferator-activated receptor-gamma in SAMP1/YitFc mice and in human Crohn's diseaseQ30435812
L-selectin, alpha 4 beta 1, and alpha 4 beta 7 integrins participate in CD4+ T cell recruitment to chronically inflamed small intestineQ30435883
Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammationQ30436253
Altered epithelial cell lineage allocation and global expansion of the crypt epithelial stem cell population are associated with ileitis in SAMP1/YitFc miceQ30436376
Probiotics promote gut health through stimulation of epithelial innate immunityQ30437282
Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel diseaseQ30437360
Leukocyte adhesion molecules in animal models of inflammatory bowel diseaseQ30437758
New concepts in the pathophysiology of inflammatory bowel diseaseQ30438997
Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's diseaseQ30439177
The primary defect in experimental ileitis originates from a nonhematopoietic sourceQ30439653
Critical role of endothelial P-selectin glycoprotein ligand 1 in chronic murine ileitisQ30439952
Role of TL1A and its receptor DR3 in two models of chronic murine ileitisQ30440458
Antibody blockade of CCL25/CCR9 ameliorates early but not late chronic murine ileitisQ30442113
Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitisQ30442649
Immunopathogenesis of inflammatory bowel disease: current conceptsQ30443776
Resistin-like molecule beta (RELMbeta/FIZZ2) is highly expressed in the ileum of SAMP1/YitFc mice and is associated with initiation of ileitisQ30444910
Absence of bacterially induced RELMbeta reduces injury in the dextran sodium sulfate model of colitisQ30445748
Early and late gut immune responses in IBD.Q30445823
Innate and adaptive immune responses related to IBD pathogenesisQ30445894
Mechanisms of tight junction dysregulation in the SAMP1/YitFc model of Crohn's disease-like ileitisQ30448602
Blockade of PSGL-1 attenuates CD14+ monocytic cell recruitment in intestinal mucosa and ameliorates ileitis in SAMP1/Yit miceQ31132998
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's diseaseQ33249005
A genetic map of the mouse suitable for typing intraspecific crossesQ33959542
Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: alternative promoter use and different splicing yield two mPPAR gamma isoformsQ34018199
Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitutionQ34440722
Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trialQ34510060
The B-cell system in inflammatory bowel diseaseQ34514530
Emerging roles of PPARs in inflammation and immunityQ34931884
Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseasesQ34992771
Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel diseaseQ35362858
Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteinsQ35747165
STAT3 activation via interleukin 6 trans-signalling contributes to ileitis in SAMP1/Yit miceQ35769017
Mucosal T-cell immunoregulation varies in early and late inflammatory bowel diseaseQ36172835
Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cellsQ36316586
T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitisQ36376495
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gammaQ36403491
Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1.Q36493604
Occludin is a functional component of the tight junction.Q36828867
High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in femalesQ37098709
The X-files in immunity: sex-based differences predispose immune responsesQ37252714
Inflammatory bowel disease and mutations affecting the interleukin-10 receptorQ37454505
Hyperactivated B cells in human inflammatory bowel diseaseQ37486515
The natural history of adult Crohn's disease in population-based cohortsQ37622752
IL-33 is upregulated in colonocytes of ulcerative colitis.Q39929368
Infliximab retreatment in adults and children with Crohn's disease: risk factors for the development of delayed severe systemic reactionQ40579493
Genetic characterization of senescence-accelerated mouse (SAM).Q41411696
Evolution of osteopenia in inflammatory bowel diseaseQ41650838
PPARgamma in monocytes: less pain, any gain?Q41755827
The liver's dance with death: two Bcl-2 guardian proteins from the abyssQ42723851
Inflammatory bowel disease-like enteritis and caecitis in a senescence accelerated mouse P1/Yit strainQ43087545
Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-alpha production in miceQ43812731
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.Q44021327
Experimental murine colitis is regulated by two genetic loci, including one on chromosome 11 that regulates IL-12 responsesQ44081504
Interleukin-5 participates in the pathogenesis of ileitis in SAMP1/Yit miceQ47431206
Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitisQ47933212
IL18 polymorphism is associated with an increased risk of Crohn's diseaseQ48260694
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment.Q51083007
Genetic analysis of susceptibility to dextran sulfate sodium-induced colitis in mice.Q54106118
A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis.Q54116272
Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis.Q54431742
Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells.Q54776568
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectCrohn's diseaseQ1472
ileitisQ3796380
P304page(s)2566-2584
P577publication date2011-05-06
P1433published inInflammatory Bowel DiseasesQ15749161
P1476titleSAMP1/YitFc mouse strain: a spontaneous model of Crohn's disease-like ileitis
P478volume17

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