review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Klaus Ley | |
Giorgos Bamias | |||
Fabio Cominelli | |||
Kristen O Arseneau | |||
Theresa T Pizarro | |||
Brian K Reuter | |||
Joseph R Mercado | |||
Luca Pastorelli | |||
Marcello Chieppa | |||
Rekha R Garg | |||
P2860 | cites work | A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease | Q22251291 |
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines | Q24294720 | ||
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL | Q24311741 | ||
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis | Q24656576 | ||
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease | Q27860821 | ||
The organization, promoter analysis, and expression of the human PPARgamma gene | Q28244071 | ||
Functional variants of OCTN cation transporter genes are associated with Crohn disease | Q28258410 | ||
Genetic variation in DLG5 is associated with inflammatory bowel disease | Q28258422 | ||
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene | Q28270603 | ||
Elevated expression of Paneth cell CRS4C in ileitis-prone SAMP1/YitFc mice: regional distribution, subcellular localization, and mechanism of action | Q28590753 | ||
Interleukin-10-deficient mice develop chronic enterocolitis | Q29547881 | ||
Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice | Q72233696 | ||
Intestinal permeability test as a predictor of clinical course in Crohn's disease | Q73081946 | ||
IL-4 exacerbates disease in a Th1 cell transfer model of colitis | Q73401136 | ||
T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells | Q74082060 | ||
Preventive effects of Bifidobacterium- and Lactobacillus-fermented milk on the development of inflammatory bowel disease in senescence-accelerated mouse P1/Yit strain mice | Q77089238 | ||
Identification of a chemokine network that recruits FoxP3(+) regulatory T cells into chronically inflamed intestine | Q79835752 | ||
Maturation of the mucosal immune system underlies colitis susceptibility in interleukin-10-deficient (IL-10-/-) mice | Q80211025 | ||
Association between IL-18 gene promoter polymorphisms and inflammatory bowel disease in a Japanese population | Q81527817 | ||
-137 (G/C) IL-18 promoter polymorphism in patients with inflammatory bowel disease | Q81550402 | ||
Probiotic Lactobacillus-induced improvement in murine chronic inflammatory bowel disease is associated with the down-regulation of pro-inflammatory cytokines in lamina propria mononuclear cells | Q81809212 | ||
Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease | Q82257596 | ||
Epithelial NEMO links innate immunity to chronic intestinal inflammation | Q59091394 | ||
VSL#3 Probiotic-Mixture Induces Remission in Patients with Active Ulcerative Colitis | Q59120549 | ||
Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12 | Q59418582 | ||
Genetic analysis in Finnish families with inflammatory bowel disease supports linkage to chromosome 3p21 | Q60475357 | ||
Distinct cytokine patterns in early and chronic ileal lesions of Crohn's disease | Q62660272 | ||
Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements | Q62819809 | ||
Evidence for an inflammatory bowel disease locus on chromosome 3p26: linkage, transmission/disequilibrium and partitioning of linkage | Q64461862 | ||
Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor | Q69656337 | ||
A new murine model of accelerated senescence | Q71011567 | ||
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 | Q29614873 | ||
Inflammatory bowel disease | Q29616286 | ||
IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells | Q30304035 | ||
Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease | Q30307038 | ||
Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice | Q30308331 | ||
Down-regulation of intestinal lymphocyte activation and Th1 cytokine production by antibiotic therapy in a murine model of Crohn's disease | Q30310154 | ||
Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis | Q30310728 | ||
Mouse models for the study of Crohn's disease | Q30310867 | ||
TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis | Q30310991 | ||
Identification of a quantitative trait locus for ileitis in a spontaneous mouse model of Crohn's disease: SAMP1/YitFc | Q30311093 | ||
Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease | Q30311921 | ||
Beta7 integrin deficiency suppresses B cell homing and attenuates chronic ileitis in SAMP1/YitFc mice | Q30429486 | ||
Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease | Q30434096 | ||
Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis | Q30434426 | ||
Linkage to peroxisome proliferator-activated receptor-gamma in SAMP1/YitFc mice and in human Crohn's disease | Q30435812 | ||
L-selectin, alpha 4 beta 1, and alpha 4 beta 7 integrins participate in CD4+ T cell recruitment to chronically inflamed small intestine | Q30435883 | ||
Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation | Q30436253 | ||
Altered epithelial cell lineage allocation and global expansion of the crypt epithelial stem cell population are associated with ileitis in SAMP1/YitFc mice | Q30436376 | ||
Probiotics promote gut health through stimulation of epithelial innate immunity | Q30437282 | ||
Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease | Q30437360 | ||
Leukocyte adhesion molecules in animal models of inflammatory bowel disease | Q30437758 | ||
New concepts in the pathophysiology of inflammatory bowel disease | Q30438997 | ||
Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease | Q30439177 | ||
The primary defect in experimental ileitis originates from a nonhematopoietic source | Q30439653 | ||
Critical role of endothelial P-selectin glycoprotein ligand 1 in chronic murine ileitis | Q30439952 | ||
Role of TL1A and its receptor DR3 in two models of chronic murine ileitis | Q30440458 | ||
Antibody blockade of CCL25/CCR9 ameliorates early but not late chronic murine ileitis | Q30442113 | ||
Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis | Q30442649 | ||
Immunopathogenesis of inflammatory bowel disease: current concepts | Q30443776 | ||
Resistin-like molecule beta (RELMbeta/FIZZ2) is highly expressed in the ileum of SAMP1/YitFc mice and is associated with initiation of ileitis | Q30444910 | ||
Absence of bacterially induced RELMbeta reduces injury in the dextran sodium sulfate model of colitis | Q30445748 | ||
Early and late gut immune responses in IBD. | Q30445823 | ||
Innate and adaptive immune responses related to IBD pathogenesis | Q30445894 | ||
Mechanisms of tight junction dysregulation in the SAMP1/YitFc model of Crohn's disease-like ileitis | Q30448602 | ||
Blockade of PSGL-1 attenuates CD14+ monocytic cell recruitment in intestinal mucosa and ameliorates ileitis in SAMP1/Yit mice | Q31132998 | ||
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease | Q33249005 | ||
A genetic map of the mouse suitable for typing intraspecific crosses | Q33959542 | ||
Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: alternative promoter use and different splicing yield two mPPAR gamma isoforms | Q34018199 | ||
Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution | Q34440722 | ||
Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial | Q34510060 | ||
The B-cell system in inflammatory bowel disease | Q34514530 | ||
Emerging roles of PPARs in inflammation and immunity | Q34931884 | ||
Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseases | Q34992771 | ||
Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease | Q35362858 | ||
Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteins | Q35747165 | ||
STAT3 activation via interleukin 6 trans-signalling contributes to ileitis in SAMP1/Yit mice | Q35769017 | ||
Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease | Q36172835 | ||
Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells | Q36316586 | ||
T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis | Q36376495 | ||
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma | Q36403491 | ||
Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1. | Q36493604 | ||
Occludin is a functional component of the tight junction. | Q36828867 | ||
High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in females | Q37098709 | ||
The X-files in immunity: sex-based differences predispose immune responses | Q37252714 | ||
Inflammatory bowel disease and mutations affecting the interleukin-10 receptor | Q37454505 | ||
Hyperactivated B cells in human inflammatory bowel disease | Q37486515 | ||
The natural history of adult Crohn's disease in population-based cohorts | Q37622752 | ||
IL-33 is upregulated in colonocytes of ulcerative colitis. | Q39929368 | ||
Infliximab retreatment in adults and children with Crohn's disease: risk factors for the development of delayed severe systemic reaction | Q40579493 | ||
Genetic characterization of senescence-accelerated mouse (SAM). | Q41411696 | ||
Evolution of osteopenia in inflammatory bowel disease | Q41650838 | ||
PPARgamma in monocytes: less pain, any gain? | Q41755827 | ||
The liver's dance with death: two Bcl-2 guardian proteins from the abyss | Q42723851 | ||
Inflammatory bowel disease-like enteritis and caecitis in a senescence accelerated mouse P1/Yit strain | Q43087545 | ||
Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-alpha production in mice | Q43812731 | ||
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. | Q44021327 | ||
Experimental murine colitis is regulated by two genetic loci, including one on chromosome 11 that regulates IL-12 responses | Q44081504 | ||
Interleukin-5 participates in the pathogenesis of ileitis in SAMP1/Yit mice | Q47431206 | ||
Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis | Q47933212 | ||
IL18 polymorphism is associated with an increased risk of Crohn's disease | Q48260694 | ||
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. | Q51083007 | ||
Genetic analysis of susceptibility to dextran sulfate sodium-induced colitis in mice. | Q54106118 | ||
A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. | Q54116272 | ||
Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis. | Q54431742 | ||
Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells. | Q54776568 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Crohn's disease | Q1472 |
ileitis | Q3796380 | ||
P304 | page(s) | 2566-2584 | |
P577 | publication date | 2011-05-06 | |
P1433 | published in | Inflammatory Bowel Diseases | Q15749161 |
P1476 | title | SAMP1/YitFc mouse strain: a spontaneous model of Crohn's disease-like ileitis | |
P478 | volume | 17 |
Q52680686 | 'Cyclical Bias' in Microbiome Research Revealed by A Portable Germ-Free Housing System Using Nested Isolation. |
Q36310800 | A novel model of colitis-associated cancer in SAMP1/YitFc mice with Crohn's disease-like ileitis |
Q47969652 | Animal models for studying epithelial barriers in neonatal necrotizing enterocolitis, inflammatory bowel disease and colorectal cancer. |
Q30402938 | Assessment of Inflammation in an Acute on Chronic Model of Inflammatory Bowel Disease with Ultrasound Molecular Imaging |
Q35276739 | Central role of IL-17/Th17 immune responses and the gut microbiota in the pathogenesis of intestinal fibrosis |
Q21131205 | Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics |
Q50966061 | Chemically induced mouse models of acute and chronic intestinal inflammation. |
Q90169782 | Chronic Model of Inflammatory Bowel Disease in IL-10-/- Transgenic Mice: Evaluation with Ultrasound Molecular Imaging |
Q26778018 | Colitis-associated colon cancer: Is it in your genes? |
Q51739535 | Death Receptor 3 Signaling Controls the Balance between Regulatory and Effector Lymphocytes in SAMP1/YitFc Mice with Crohn's Disease-Like Ileitis. |
Q57184753 | Death-Domain-Receptor 3 Deletion Normalizes Inflammatory Gene Expression and Prevents Ileitis in Experimental Crohn's Disease |
Q37240497 | Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation |
Q35880725 | Dysregulated intrahepatic CD4(+) T-cell activation drives liver inflammation in ileitis-prone SAMP1/YitFc mice |
Q36444778 | Emerging role of the interleukin (IL)-33/ST2 axis in gut mucosal wound healing and fibrosis. |
Q38801764 | Eosinophils, probiotics, and the microbiome. |
Q50093819 | Epicutaneous Tolerance Induction to a Bystander Antigen Abrogates Colitis and Ileitis in Mice |
Q51158560 | Epithelial-specific Toll-like Receptor (TLR)5 Activation Mediates Barrier Dysfunction in Experimental Ileitis. |
Q28077774 | Facing Terminal Ileitis: Going Beyond Crohn's Disease |
Q39453646 | Factors Promoting Development of Fibrosis in Crohn's Disease |
Q42018048 | Functional defects in NOD2 signaling in experimental and human Crohn disease |
Q33694206 | Genetic deletion of the bacterial sensor NOD2 improves murine Crohn's disease-like ileitis independent of functional dysbiosis. |
Q39974669 | IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis. |
Q57050128 | IL-33 promotes recovery from acute colitis by inducing miR-320 to stimulate epithelial restitution and repair |
Q26998386 | Imaging modalities for the noninvasive assessment of fibrosis in Crohn's disease |
Q41742020 | In vivo inhibition of RIPK2 kinase alleviates inflammatory disease |
Q42128152 | Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88 |
Q88097800 | Inflammatory bowel disease |
Q64078046 | Intestinal Organoids as a Novel Complementary Model to Dissect Inflammatory Bowel Disease |
Q27022092 | Intestinal epithelium in inflammatory bowel disease |
Q37585773 | Large Animal Models: The Key to Translational Discovery in Digestive Disease Research |
Q30407800 | Loss of estrogen-mediated immunoprotection underlies female gender bias in experimental Crohn's-like ileitis. |
Q26774688 | Mechanisms of Microbe-Host Interaction in Crohn's Disease: Dysbiosis vs. Pathobiont Selection |
Q26741117 | Mucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel Disease |
Q44917386 | Multi-omics Comparative Analysis Reveals Multiple Layers of Host Signaling Pathway Regulation by the Gut Microbiota |
Q64448364 | Murine Adherent and Invasive E. coli Induces Chronic Inflammation and Immune Responses in the Small and Large Intestines of Monoassociated IL-10-/- Mice Independent of Long Polar Fimbriae Adhesin A |
Q26863622 | Murine models of inflammatory bowel disease (IBD): challenges of modeling human disease |
Q26823773 | New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation |
Q35701552 | Occurrence of spontaneous periodontal disease in the SAMP1/YitFc murine model of Crohn disease. |
Q36994761 | Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease |
Q94451654 | Paneth cell α-defensin misfolding correlates with dysbiosis and ileitis in Crohn's disease model mice |
Q38593257 | Pathway-based approaches to the treatment of inflammatory bowel disease |
Q92266526 | Phosphatidylinositol 3-kinase p110δ drives intestinal fibrosis in SHIP deficiency |
Q35691021 | Porcine models of digestive disease: the future of large animal translational research. |
Q30425823 | Probiotic bacteria regulate intestinal epithelial permeability in experimental ileitis by a TNF-dependent mechanism |
Q35147482 | Results of the 4th scientific workshop of the ECCO (I): pathophysiology of intestinal fibrosis in IBD. |
Q41899805 | SAMP1/YitFc mice develop ileitis via loss of CCL21 and defects in dendritic cell migration |
Q51759251 | Secreted Klotho Attenuates Inflammation-Associated Aortic Valve Fibrosis in Senescence-Accelerated Mice P1. |
Q99234081 | Sex matters: impact on pathogenesis, presentation and treatment of inflammatory bowel disease |
Q35812593 | Spontaneous and transgenic rodent models of inflammatory bowel disease |
Q30424223 | Spontaneous, immune-mediated gastric inflammation in SAMP1/YitFc mice, a model of Crohn's-like gastritis. |
Q30658529 | Stereomicroscopic 3D-pattern profiling of murine and human intestinal inflammation reveals unique structural phenotypes |
Q42134460 | T Lymphocyte Dynamics in Inflammatory Bowel Diseases: Role of the Microbiome. |
Q64111557 | TL1A (TNFSF15) and DR3 (TNFRSF25): A Co-stimulatory System of Cytokines With Diverse Functions in Gut Mucosal Immunity |
Q92633474 | TWEAK/Fn14 Is Overexpressed in Crohn's Disease and Mediates Experimental Ileitis by Regulating Critical Innate and Adaptive Immune Pathways |
Q52648684 | The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn's Disease-Like Ileitis. |
Q41108985 | The features of intestinal tuberculosis by contrast-enhanced ultrasound |
Q88879271 | The interplay between microbes and the immune response in inflammatory bowel disease |
Q36914110 | The role of IL-33 in gut mucosal inflammation. |
Q38534313 | Tumor Necrosis Factor-like Cytokine TL1A and Its Receptors DR3 and DcR3: Important New Factors in Mucosal Homeostasis and Inflammation |
Q40047893 | Ultrasound-guided Intracardiac Injection of Human Mesenchymal Stem Cells to Increase Homing to the Intestine for Use in Murine Models of Experimental Inflammatory Bowel Diseases |
Q33711741 | Uncovering Pathogenic Mechanisms of Inflammatory Bowel Disease Using Mouse Models of Crohn's Disease-Like Ileitis: What is the Right Model? |
Q34367448 | Whole-genome microarray analysis and functional characterization reveal distinct gene expression profiles and patterns in two mouse models of ileal inflammation. |
Q48175668 | γδ T Cells Coexpressing Gut Homing α4β7 and αE Integrins Define a Novel Subset Promoting Intestinal Inflammation. |
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