review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Vesna Jevtovic-Todorovic | Q60642341 |
P2093 | author name string | Slobodan M Todorovic | |
P2860 | cites work | Molecular characterization of a neuronal low-voltage-activated T-type calcium channel | Q24316054 |
Activation of corticotropin-releasing factor receptor 1 selectively inhibits CaV3.2 T-type calcium channels | Q24316197 | ||
Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2+ channel gene family | Q24316347 | ||
The molecular basis for T-type Ca2+ channel inhibition by G protein beta2gamma2 subunits. | Q24676565 | ||
Structure and regulation of voltage-gated Ca2+ channels | Q28141138 | ||
T-type calcium channel regulation by specific G-protein betagamma subunits | Q28186366 | ||
Molecular physiology of low-voltage-activated t-type calcium channels | Q28200827 | ||
Attenuated pain responses in mice lacking Ca(V)3.2 T-type channels | Q28260743 | ||
The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function | Q28289375 | ||
Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons | Q28342691 | ||
Stimulation of recombinant Ca(v)3.2, T-type, Ca(2+) channel currents by CaMKIIgamma(C) | Q28345043 | ||
Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide | Q28366316 | ||
Determinants of voltage-dependent inactivation affect Mibefradil block of calcium channels | Q28369869 | ||
Hyperalgesia induced by spinal and peripheral hydrogen sulfide: evidence for involvement of Cav3.2 T-type calcium channels | Q28567108 | ||
Regulation of T-type calcium channels by Rho-associated kinase | Q28568889 | ||
Synaptic plasticity in spinal lamina I projection neurons that mediate hyperalgesia | Q28582696 | ||
Specific properties of T-type calcium channels generated by the human alpha 1I subunit. | Q47872006 | ||
A comparison of the burst activity of lateral thalamic neurons in chronic pain and non-pain patients | Q48202046 | ||
Mibefradil inhibition of T-type calcium channels in cerebellar purkinje neurons | Q48327297 | ||
Enantioselective blockade of T-type Ca2+ current in adult rat sensory neurons by a steroid that lacks gamma-aminobutyric acid-modulatory activity | Q48357310 | ||
Profiling the array of Ca(v)3.1 variants from the human T-type calcium channel gene CACNA1G: alternative structures, developmental expression, and biophysical variations | Q48557743 | ||
Inhibition of T-type voltage-gated calcium channels by a new scorpion toxin | Q48921080 | ||
Differences in Ca2+ channels governing generation of miniature and evoked excitatory synaptic currents in spinal laminae I and II. | Q51496112 | ||
Hydrogen sulfide as a novel nociceptive messenger. | Q53566710 | ||
Variation in serotonergic inhibition of calcium channel currents in four types of rat sensory neurons differentiated by membrane properties. | Q54158540 | ||
Role of T-Type Calcium Current in Identified D-Hair Mechanoreceptor Neurons Studied In Vitro | Q56980269 | ||
Low- and high-voltage-activated calcium currents in rat spinal dorsal horn neurons | Q67655338 | ||
T-type calcium channels: heterogeneous expression in rat sensory neurons and selective modulation by phorbol esters | Q68453576 | ||
GABAA-receptor-activated current in dorsal root ganglion neurons freshly isolated from adult rats | Q68473432 | ||
Amiloride selectively blocks the low threshold (T) calcium channel | Q69022800 | ||
Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli | Q71228225 | ||
Voltage-dependent calcium currents are enhanced in dorsal root ganglion neurones from the Bio Bred/Worchester diabetic rat | Q71513386 | ||
Myelinated afferent fibres responding specifically to noxious stimulation of the skin | Q72291143 | ||
Presynaptic receptors | Q74578161 | ||
Intrathecal administration of Cav3.2 and Cav3.3 antisense oligonucleotide reverses tactile allodynia and thermal hyperalgesia in rats following chronic compression of dorsal root of ganglion | Q79368090 | ||
Tuning thalamic firing modes via simultaneous modulation of T- and L-type Ca2+ channels controls pain sensory gating in the thalamus | Q82816941 | ||
Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels | Q30303630 | ||
Alternative splicing of the rat Ca(v)3.3 T-type calcium channel gene produces variants with distinct functional properties(1). | Q30309951 | ||
A mechanism for the direct regulation of T-type calcium channels by Ca2+/calmodulin-dependent kinase II. | Q30311927 | ||
Structural determinants of the high affinity extracellular zinc binding site on Cav3.2 T-type calcium channels | Q30433407 | ||
A modeling study of T-type Ca2+ channel gating and modulation by L-cysteine in rat nociceptors | Q30433450 | ||
Redox modulation of peripheral T-type Ca2+ channels in vivo: alteration of nerve injury-induced thermal hyperalgesia | Q30433597 | ||
Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway | Q30433716 | ||
Functional impact of alternative splicing of human T-type Cav3.3 calcium channels | Q30433971 | ||
5beta-reduced neuroactive steroids are novel voltage-dependent blockers of T-type Ca2+ channels in rat sensory neurons in vitro and potent peripheral analgesics in vivo | Q30434076 | ||
Selective T-type calcium channel blockade alleviates hyperalgesia in ob/ob mice | Q30434283 | ||
In vivo silencing of the Ca(V)3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy | Q30434954 | ||
Contrasting anesthetic sensitivities of T-type Ca2+ channels of reticular thalamic neurons and recombinant Ca(v)3.3 channels | Q30435619 | ||
New evidence that both T-type calcium channels and GABAA channels are responsible for the potent peripheral analgesic effects of 5alpha-reduced neuroactive steroids | Q30436316 | ||
Protein kinase A activity controls the regulation of T-type CaV3.2 channels by Gbetagamma dimers | Q30436711 | ||
5alpha-reduced neuroactive steroids alleviate thermal and mechanical hyperalgesia in rats with neuropathic pain | Q30437972 | ||
The endogenous redox agent L-cysteine induces T-type Ca2+ channel-dependent sensitization of a novel subpopulation of rat peripheral nociceptors. | Q30438110 | ||
Upregulation of the T-type calcium current in small rat sensory neurons after chronic constrictive injury of the sciatic nerve | Q30439844 | ||
CaV3.2 is the major molecular substrate for redox regulation of T-type Ca2+ channels in the rat and mouse thalamus | Q30440317 | ||
Cell-specific alterations of T-type calcium current in painful diabetic neuropathy enhance excitability of sensory neurons | Q30443224 | ||
Reducing agents sensitize C-type nociceptors by relieving high-affinity zinc inhibition of T-type calcium channels | Q30444180 | ||
Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate | Q30444989 | ||
Nickel block of three cloned T-type calcium channels: low concentrations selectively block alpha1H. | Q30447500 | ||
Free radical signalling underlies inhibition of CaV3.2 T-type calcium channels by nitrous oxide in the pain pathway | Q30452208 | ||
A T-type calcium channel required for normal function of a mammalian mechanoreceptor | Q33187408 | ||
The vanilloid receptor: a molecular gateway to the pain pathway | Q33941065 | ||
Specificity of cold thermotransduction is determined by differential ionic channel expression | Q34113463 | ||
Kinetic and pharmacological properties of low voltage-activated Ca2+ current in rat clonal (GH3) pituitary cells. | Q34237255 | ||
Abnormal coronary function in mice deficient in alpha1H T-type Ca2+ channels | Q34278287 | ||
Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane | Q34292344 | ||
Low-threshold calcium spike bursts in the human thalamus. Common physiopathology for sensory, motor and limbic positive symptoms | Q34396629 | ||
Pharmacological properties of T-type Ca2+ current in adult rat sensory neurons: effects of anticonvulsant and anesthetic agents | Q34451739 | ||
Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin | Q34464493 | ||
On the action of the anti-absence drug ethosuximide in the rat and cat thalamus. | Q34472682 | ||
Synaptic amplifier of inflammatory pain in the spinal dorsal horn | Q34538726 | ||
Posttranslational mechanisms of peripheral sensitization | Q35884837 | ||
Pharmacological dissection and distribution of NaN/Nav1.9, T-type Ca2+ currents, and mechanically activated cation currents in different populations of DRG neurons | Q36295971 | ||
Mechanism of arachidonic acid modulation of the T-type Ca2+ channel alpha1G | Q36445341 | ||
Pharmacology and drug discovery for T-type calcium channels | Q36683558 | ||
Towards the discovery of novel T-type calcium channel blockers. | Q36804457 | ||
Opiate-mediated inhibition of calcium signaling is decreased in dorsal root ganglion neurons from the diabetic BB/W rat. | Q37352328 | ||
Activation of protein kinase C augments T-type Ca2+ channel activity without changing channel surface density | Q38508607 | ||
In vitro characterization of T-type calcium channel antagonist TTA-A2 and in vivo effects on arousal in mice. | Q39671872 | ||
Structural and biophysical determinants of single Ca(V)3.1 and Ca(V)3.2 T-type calcium channel inhibition by N(2)O. | Q39794785 | ||
Temperature-dependent modulation of CaV3 T-type calcium channels by protein kinases C and A in mammalian cells. | Q40081052 | ||
A selective T-type Ca2+ channel blocker R(-) efonidipine | Q40123411 | ||
Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors. | Q40126566 | ||
Alternatively spliced alpha(1G) (Ca(V)3.1) intracellular loops promote specific T-type Ca(2+) channel gating properties. | Q40179790 | ||
Chemical determinants involved in anandamide-induced inhibition of T-type calcium channels. | Q40205455 | ||
Subunit-specific modulation of T-type calcium channels by zinc. | Q40212704 | ||
A profile of alternative RNA splicing and transcript variation of CACNA1H, a human T-channel gene candidate for idiopathic generalized epilepsies | Q40339373 | ||
Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence | Q40485751 | ||
Expression of T-type calcium channel splice variants in human glioma. | Q40513808 | ||
NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: a new selective inhibitor of T-type calcium channels | Q40600165 | ||
Kurtoxin, a gating modifier of neuronal high- and low-threshold ca channels. | Q40653150 | ||
Differential inhibition of T-type calcium channels by neuroleptics. | Q40757971 | ||
Redox modulation of T-type calcium channels in rat peripheral nociceptors | Q40787127 | ||
Arachidonic acid modulation of alpha1H, a cloned human T-type calcium channel | Q40904445 | ||
Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception. | Q40949695 | ||
Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family | Q40969230 | ||
Low-threshold calcium currents in central nervous system neurons. | Q41117703 | ||
T-type Ca2+ channels and pharmacological blockade: potential pathophysiological relevance | Q41725880 | ||
Elevated thalamic low-voltage-activated currents precede the onset of absence epilepsy in the SNAP25-deficient mouse mutant coloboma. | Q42628548 | ||
Ca(v)3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain. | Q42946191 | ||
Upregulation of Ca(v)3.2 T-type calcium channels targeted by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain | Q43024302 | ||
T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids. | Q43257249 | ||
Effects of ethosuximide, a T-type Ca(2+) channel blocker, on dorsal horn neuronal responses in rats | Q43557368 | ||
L-type and T-type calcium channel blockade potentiate the analgesic effects of morphine and selective mu opioid agonist, but not to selective delta and kappa agonist at the level of the spinal cord in mice | Q43640188 | ||
Impaired inhibitory G-protein function contributes to increased calcium currents in rats with diabetic neuropathy | Q43701685 | ||
Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G) T-type Ca(2+) channels | Q43702724 | ||
Ca(v)3.2 channel is a molecular substrate for inhibition of T-type calcium currents in rat sensory neurons by nitrous oxide | Q43705779 | ||
Differential sensitivity of N- and P/Q-type Ca2+ channel currents to a mu opioid in isolectin B4-positive and -negative dorsal root ganglion neurons | Q44346268 | ||
Reversal of experimental neuropathic pain by T-type calcium channel blockers | Q44589954 | ||
Thalamic Control of Visceral Nociception Mediated by T-Type Ca 2+ Channels | Q44606624 | ||
Ethosuximide reverses paclitaxel- and vincristine-induced painful peripheral neuropathy | Q44843038 | ||
State-dependent mibefradil block of Na+ channels | Q45161630 | ||
Hydrogen sulfide as a novel mediator for pancreatic pain in rodents. | Q46000821 | ||
Luminal hydrogen sulfide plays a pronociceptive role in mouse colon | Q46318763 | ||
Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonist | Q46550414 | ||
Calcium current variation between acutely isolated adult rat dorsal root ganglion neurons of different size | Q46939264 | ||
Correlation of cell body size, axon size, and signal conduction velocity for individually labelled dorsal root ganglion cells in the cat. | Q47213232 | ||
Role of the alpha1G T-type calcium channel in spontaneous absence seizures in mutant mice. | Q47400321 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | voltage | Q25428 |
P304 | page(s) | 484-495 | |
P577 | publication date | 2011-06-01 | |
P1433 | published in | British Journal of Pharmacology | Q919631 |
P1476 | title | T-type voltage-gated calcium channels as targets for the development of novel pain therapies | |
P478 | volume | 163 |
Q31170459 | 1,4-Dihydropyridine derivatives with T-type calcium channel blocking activity attenuate inflammatory and neuropathic pain. |
Q44177463 | 5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone. |
Q40057939 | A Randomized, Double-Blind, Placebo-Controlled, Crossover Study of the T-Type Calcium Channel Blocker ABT-639 in an Intradermal Capsaicin Experimental Pain Model in Healthy Adults |
Q41202785 | A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors |
Q47957480 | A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain |
Q91012466 | A novel phospho-modulatory mechanism contributes to the calcium-dependent regulation of T-type Ca2+ channels |
Q36628308 | A randomized double-blind, placebo-, and active-controlled study of T-type calcium channel blocker ABT-639 in patients with diabetic peripheral neuropathic pain |
Q39290501 | AKAP-dependent sensitization of Ca(v) 3.2 channels via the EP(4) receptor/cAMP pathway mediates PGE(2) -induced mechanical hyperalgesia |
Q55287316 | Accumulation of Cav3.2 T-type Calcium Channels in the Uninjured Sural Nerve Contributes to Neuropathic Pain in Rats with Spared Nerve Injury. |
Q30541205 | Analgesic effect of a mixed T-type channel inhibitor/CB2 receptor agonist |
Q30528512 | CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy-induced painful peripheral neuropathy |
Q58582878 | CRMP2 and voltage-gated ion channels: potential roles in neuropathic pain |
Q30413912 | CaV3.2 T-type calcium channels in peripheral sensory neurons are important for mibefradil-induced reversal of hyperalgesia and allodynia in rats with painful diabetic neuropathy |
Q37360619 | Challenging the catechism of therapeutics for chronic neuropathic pain: Targeting CaV2.2 interactions with CRMP2 peptides |
Q41013852 | Changes in Ionic Conductance Signature of Nociceptive Neurons Underlying Fabry Disease Phenotype. |
Q30631622 | Characterization of novel cannabinoid based T-type calcium channel blockers with analgesic effects |
Q41941144 | Differences in peripheral endocannabinoid modulation of scratching behavior in facial vs. spinally-innervated skin |
Q38211114 | Diverse mechanisms underlying the regulation of ion channels by carbon monoxide |
Q33843306 | Epigenetic modification of DRG neuronal gene expression subsequent to nerve injury: etiological contribution to complex regional pain syndromes (Part I). |
Q41852098 | Evaluation of lercanidipine in Paclitaxel-induced neuropathic pain model in rat: a preliminary study |
Q35606660 | Expression and Regulation of Cav3.2 T-Type Calcium Channels during Inflammatory Hyperalgesia in Mouse Dorsal Root Ganglion Neurons |
Q47566382 | From Mechanism to Cure: Renewing the Goal to Eliminate the Disease of Pain |
Q41893886 | Gabapentin reverses central pain sensitization following a collagenase-induced intrathalamic hemorrhage in rats |
Q38545028 | H2S and Pain: A Novel Aspect for Processing of Somatic, Visceral and Neuropathic Pain Signals |
Q30410268 | Immunohistological demonstration of CaV3.2 T-type voltage-gated calcium channel expression in soma of dorsal root ganglion neurons and peripheral axons of rat and mouse |
Q47704920 | In vitro neurotoxicity by ropivacaine is reduced by silencing Cav3.3 T-type calcium subunits in neonatal rat sensory neurons |
Q35642202 | Inhibition of T-Type Voltage Sensitive Calcium Channel Reduces Load-Induced OA in Mice and Suppresses the Catabolic Effect of Bone Mechanical Stress on Chondrocytes |
Q40611639 | Inhibition of T-type Ca2+ Channels by Hydrogen Sulfide |
Q30417996 | Inhibition of T-type calcium current in rat thalamocortical neurons by isoflurane |
Q64255589 | Inhibition of multiple voltage-gated calcium channels may contribute to spinally mediated analgesia by epipregnanolone in a rat model of surgical paw incision |
Q92861475 | KLHL1 Controls CaV3.2 Expression in DRG Neurons and Mechanical Sensitivity to Pain |
Q44921188 | Modulation of T-type Ca2+ channels by Lavender and Rosemary extracts. |
Q38188442 | Modulation of T-type calcium channels by bioactive lipids. |
Q33822127 | N-type calcium current, Cav2.2, is enhanced in small-diameter sensory neurons isolated from Nf1+/- mice |
Q43712077 | Neuromedin U receptor 2 does not play a role in the development of neuropathic pain following nerve injury in mice. |
Q38228215 | Neuronal calcium signaling in chronic pain |
Q38692763 | Neuroplasticity of ascending and descending pathways after somatosensory system injury: reviewing knowledge to identify neuropathic pain therapeutic targets |
Q38217614 | New investigational drugs for the treatment of neuropathic pain |
Q37623368 | Nociceptive neurons differentially express fast and slow T-type Ca²⁺ currents in different types of diabetic neuropathy |
Q30352607 | Painful Diabetic Neuropathy: Prevention or Suppression? |
Q36646432 | Pathophysiological implication of CaV3.1 T-type Ca2+ channels in trigeminal neuropathic pain |
Q96136089 | Pathophysiological roles and therapeutic potential of voltage-gated ion channels (VGICs) in pain associated with herpesvirus infection |
Q48493768 | Peripheral pain is enhanced by insulin-like growth factor 1 through a G protein-mediated stimulation of T-type calcium channels |
Q61047815 | Prescription Opioid Fatalities: Examining Why the Healer Could be the Culprit |
Q30422994 | Presynaptic Cav3.2 channels regulate excitatory neurotransmission in nociceptive dorsal horn neurons |
Q53070307 | Reduced excitability of gp130-deficient nociceptors is associated with increased voltage-gated potassium currents and Kcna4 channel upregulation. |
Q40150082 | Regulation of T-type Ca(2+) channel expression by herpes simplex virus-1 infection in sensory-like ND7 cells. |
Q35168446 | Regulation of neuronal cav3.1 channels by cyclin-dependent kinase 5 (Cdk5) |
Q30409746 | Reversal of neuropathic pain in diabetes by targeting glycosylation of Ca(V)3.2 T-type calcium channels |
Q54997398 | Role of Transient Receptor Potential Ankyrin 1 Ion Channel and Somatostatin sst4 Receptor in the Antinociceptive and Anti-inflammatory Effects of Sodium Polysulfide and Dimethyl Trisulfide. |
Q44581351 | Roles of Cav3.2 and TRPA1 channels targeted by hydrogen sulfide in pancreatic nociceptive processing in mice with or without acute pancreatitis |
Q38021306 | Sensory neurons, ion channels, inflammation and the onset of neuropathic pain. |
Q38210964 | Size does matter! Label-free detection of small molecule-protein interaction |
Q42073244 | Sumatriptan inhibition of N-type calcium channel mediated signaling in dural CGRP terminal fibres. |
Q38701037 | Surfen is a broad-spectrum calcium channel inhibitor with analgesic properties in mouse models of acute and chronic inflammatory pain |
Q38177667 | T-type channels buddy up. |
Q28306961 | Targeting of CaV3.2 T-type calcium channels in peripheral sensory neurons for the treatment of painful diabetic neuropathy |
Q38020929 | Targeting voltage-gated calcium channels: developments in peptide and small-molecule inhibitors for the treatment of neuropathic pain |
Q55311553 | The Low-Threshold Calcium Channel Cav3.2 Mediates Burst Firing of Mature Dentate Granule Cells. |
Q38105331 | The design and discovery of T-type calcium channel inhibitors for the treatment of central nervous system disorders |
Q44295791 | The failed and future promise of intraspinal drug administration for neurologic disorders |
Q36158968 | Topical application of disodium isostearyl 2-O-L-ascorbyl phosphate, an amphiphilic ascorbic acid derivative, reduces neuropathic hyperalgesia in rats |
Q36807192 | Venom peptides as a rich source of cav2.2 channel blockers |
Q41381440 | [EXPRESS] Topical moringin-cream relieves neuropathic pain by suppression of inflammatory pathway and voltage-gated ion channels in murine model of multiple sclerosis |
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