Reducing agents sensitize C-type nociceptors by relieving high-affinity zinc inhibition of T-type calcium channels

scientific article

Reducing agents sensitize C-type nociceptors by relieving high-affinity zinc inhibition of T-type calcium channels is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.1800-07.2007
P932PMC publication ID6673068
P698PubMed publication ID17670971
P5875ResearchGate publication ID6168297

P50authorEdward Perez-ReyesQ56951168
Iuliia VitkoQ62607256
P2093author name stringEdward Perez-Reyes
Hee-Sup Shin
Michael T Nelson
Slobodan M Todorovic
Ho-Won Kang
Iuliia Vitko
Jiwan Woo
Jung-Ha Lee
Paula Q Barrett
P2860cites workMolecular characterization of a neuronal low-voltage-activated T-type calcium channelQ24316054
Functional characterization and neuronal modeling of the effects of childhood absence epilepsy variants of CACNA1H, a T-type calcium channelQ28250190
Metals, toxicity and oxidative stressQ28250561
Attenuated pain responses in mice lacking Ca(V)3.2 T-type channelsQ28260743
Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channelsQ28585240
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesiaQ29620385
Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channelsQ30303630
A mechanism for the direct regulation of T-type calcium channels by Ca2+/calmodulin-dependent kinase II.Q30311927
The endogenous redox agent L-cysteine induces T-type Ca2+ channel-dependent sensitization of a novel subpopulation of rat peripheral nociceptors.Q30438110
CaV3.2 is the major molecular substrate for redox regulation of T-type Ca2+ channels in the rat and mouse thalamusQ30440317
Nickel block of three cloned T-type calcium channels: low concentrations selectively block alpha1H.Q30447500
Three pairs of cysteine residues mediate both redox and zn2+ modulation of the nmda receptor.Q31840723
Inhibitory zinc-enriched terminals in mouse spinal cordQ31962385
Abnormal coronary function in mice deficient in alpha1H T-type Ca2+ channelsQ34278287
ASIC1a-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagentsQ34527569
Posttranslational mechanisms of peripheral sensitizationQ35884837
Zinc and copper: pharmacological probes and endogenous modulators of neuronal excitability.Q36367146
Skin bioavailability of dietary vitamin E, carotenoids, polyphenols, vitamin C, zinc and seleniumQ36572844
A molecular determinant of nickel inhibition in Cav3.2 T-type calcium channelsQ38511758
Clonidine potentiates the neuropathic pain-relieving action of MK-801 while preventing its neurotoxic and hyperactivity side effectsQ39448869
Clinical features of pruritus among patients undergoing maintenance hemodialysisQ39564303
Subunit-specific modulation of T-type calcium channels by zinc.Q40212704
Reducing and oxidizing agents sensitize heat-activated vanilloid receptor (TRPV1) currentQ40292678
Divalent metals differentially block cloned T-type calcium channelsQ40636658
Redox modulation of T-type calcium channels in rat peripheral nociceptorsQ40787127
The design of metal-binding sites in proteinsQ40832965
Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception.Q40949695
Appearance of individual amino acid concentrations in arterial blood during steady-state infusions of different amino acid formulations to ICU patients in support of whole-body protein metabolismQ42497474
Redox modulation of GABAA receptors obscured by Zn2+ complexationQ42527713
Coordination of heavy metals by dithiothreitol, a commonly used thiol group protectant.Q43593312
Lactate enhances the acid-sensing Na+ channel on ischemia-sensing neuronsQ43723705
A role for the redox site in the modulation of the NMDA receptor by lightQ44232769
Reversible modulation of GABA(A) receptor-mediated currents by light is dependent on the redox state of the receptorQ44465575
Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptorQ46028475
Calcium current variation between acutely isolated adult rat dorsal root ganglion neurons of different sizeQ46939264
Modulation of inhibitory glycine receptors in cultured embryonic mouse hippocampal neurons by zinc, thiol containing redox agents and carnosineQ46974449
Redox modulation of recombinant human GABA(A) receptorsQ48888464
Four residues of the extracellular N-terminal domain of the NR2A subunit control high-affinity Zn2+ binding to NMDA receptorsQ48892598
Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptorQ48913312
High-affinity zinc inhibition of NMDA NR1-NR2A receptorsQ48954602
Variation in serotonergic inhibition of calcium channel currents in four types of rat sensory neurons differentiated by membrane properties.Q54158540
Electrophysiological differences between nociceptive and non-nociceptive dorsal root ganglion neurones in the rat in vivoQ60736394
Uremic pruritus. Clinical and experimental studiesQ69713747
Conduction velocity is related to morphological cell type in rat dorsal root ganglion neuronesQ70114271
Sensitization of nociceptive C-fibers in zinc-deficient ratsQ71701365
Proton potentiation of ATP-gated ion channel responses to ATP and Zn2+ in rat nodose ganglion neuronsQ71804424
Subclassified acutely dissociated cells of rat DRG: histochemistry and patterns of capsaicin-, proton-, and ATP-activated currentsQ73163268
Manipulations of zinc in the spinal cord, by intrathecal injection of zinc chloride, disodium-calcium-EDTA, or dipicolinic acid, alter nociceptive activity in miceQ73746664
The distribution of zinc selenite and expression of metallothionein-III mRNA in the spinal cord and dorsal root ganglia of the rat suggest a role for zinc in sensory transmissionQ74582931
Zinc alleviates thermal hyperalgesia due to partial nerve injuryQ77919144
Mechanisms of neuropathic painQ79173262
P433issue31
P407language of work or nameEnglishQ1860
P304page(s)8250-8260
P577publication date2007-08-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleReducing agents sensitize C-type nociceptors by relieving high-affinity zinc inhibition of T-type calcium channels
P478volume27

Reverse relations

cites work (P2860)
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