Genetic polymorphism of the OPG gene associated with breast cancer

scientific article

Genetic polymorphism of the OPG gene associated with breast cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1045576878
P356DOI10.1186/1471-2407-13-40
P932PMC publication ID3563620
P698PubMed publication ID23369128
P5875ResearchGate publication ID235390010

P50authorMichael PfreundschuhQ1928879
Ingolf Juhasz-BoessQ38297180
P2093author name stringRainer Maria Bohle
Stefan Graeber
Gunter Assmann
Erich Franz Solomayer
Frank Gruenhage
Jasmin Teresa Ney
P2860cites workOsteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
RANK is essential for osteoclast and lymph node developmentQ24598872
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationQ24603266
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancerQ24605866
Genome-wide association study identifies novel breast cancer susceptibility lociQ24645441
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligandQ24653311
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland developmentQ28142247
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesisQ28294501
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancerQ28303909
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancerQ28924377
Potential novel candidate polymorphisms identified in genome-wide association study for breast cancer susceptibilityQ28943457
Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studiesQ29614869
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligandQ29619331
Single nucleotide polymorphisms associated with risk for contralateral breast cancer in the Women's Environment, Cancer, and Radiation Epidemiology (WECARE) StudyQ30427359
Genetic polymorphisms of OPG, RANK, and ESR1 and bone mineral density in Korean postmenopausal womenQ33223040
Association between osteoprotegerin gene polymorphism and bone mineral density in patients with adolescent idiopathic scoliosisQ33972264
Association between genetic variants in the 8q24 cancer risk regions and circulating levels of androgens and sex hormone-binding globulinQ33981705
8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.Q34006369
Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer developmentQ34091855
"Single nucleotide polymorphisms of the OPG/RANKL system genes in primary hyperparathyroidism and their relationship with bone mineral density".Q34106682
Association between breast cancer laterality and tumor location, United States, 1994-1998.Q34549676
Cancer and laterality: a study of the five major paired organs (UK).Q34566741
Clinical features of metastatic bone disease and risk of skeletal morbidityQ34576366
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancerQ34631785
Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control studyQ34865460
Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortiumQ35166701
Influence of polymorphisms in the RANKL/RANK/OPG signaling pathway on volumetric bone mineral density and bone geometry at the forearm in men.Q35549417
RANKL/RANK/OPG: new therapeutic targets in bone tumours and associated osteolysisQ35885679
Reproductive aging-associated common genetic variants and the risk of breast cancerQ36245573
Lung cancer. A statistical study based on autopsy data from 1928 to 1972Q36849237
Association analyses suggest the effects of RANK and RANKL on age at menarche in Chinese women.Q36928773
Association between osteoprotegerin G1181C and T245G polymorphisms and diabetic charcot neuroarthropathy: a case-control studyQ37319080
Breast cancer genome-wide association studies: there is strength in numbersQ37945448
Unilateral breast-feeding and breast cancerQ39442663
Osteoprotegerin overexpression by breast cancer cells enhances orthotopic and osseous tumor growth and contrasts with that delivered therapeutically.Q40296427
Regulation of cancer cell migration and bone metastasis by RANKL.Q40298349
Laterality, maldescent, trauma and other clinical factors in the epidemiology of testis cancer in Victoria, AustraliaQ42373213
Osteoprotegerin and RANKL differentially regulate angiogenesis and endothelial cell functionQ42446964
Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind studyQ42829926
The relationship between Receptor Activator of Nuclear Factor-kappaB Ligand (RANKL) gene polymorphism and aortic calcification in Korean womenQ43079237
Associations between HLA-DRB1, RANK, RANKL, OPG, and IL-17 genotypes and disease severity phenotypes in Japanese patients with early rheumatoid arthritisQ43476748
Genetic polymorphisms and other risk factors associated with bisphosphonate induced osteonecrosis of the jaw.Q43844827
Polymorphisms in the osteoprotegerin gene are associated with osteoporotic fracturesQ44049677
Body mass index, serum sex hormones, and breast cancer risk in postmenopausal womenQ44472863
Vascular endothelial growth factor up-regulates expression of receptor activator of NF-kappa B (RANK) in endothelial cells. Concomitant increase of angiogenic responses to RANK ligandQ44534331
Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men.Q45298906
Expression pattern of receptor activator of NFκB (RANK) in a series of primary solid tumors and related bone metastasesQ45814967
Breast size, handedness and breast cancer riskQ47436720
Serum osteoprotegerin (OPG) and the A163G polymorphism in the OPG promoter region are related to peripheral measures of bone mass and fracture odds ratiosQ48003835
Sleep on the right side-Get cancer on the left?Q48392795
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24.Q50674084
Genetic variation in the TNFRSF11A gene encoding RANK is associated with susceptibility to Paget's disease of bone.Q51558602
Expression of receptor activator of nuclear factor kappaB ligand on bone marrow plasma cells correlates with osteolytic bone disease in patients with multiple myeloma.Q52952110
TNFRSF11B gene polymorphisms 1181G > C and 245T > G as well as haplotype CT influence bone mineral density in postmenopausal women.Q53774658
Genetic variations in the genes encoding receptor activator nuclear factor κ B (RANK), receptor activator nuclear factor κ B ligand (RANKL) and osteoprotegerin (OPG) in patients with psoriasis and psoriatic arthritis: a case-control study.Q54385952
The influence of Lys3Asn polymorphism in the osteoprotegerin gene on bone mineral density in Chinese postmenopausal women.Q54674721
Genetic variation in the RANKL/RANK/OPG signaling pathway is associated with bone turnover and bone mineral density in menQ57322613
Evidence for a link between TNFRSF11A and risk of breast cancerQ57881796
Effects of denosumab on bone turnover markers in postmenopausal osteoporosisQ58970691
Genetic Variations in Genes Encoding RANK, RANKL, and OPG in Rheumatoid Arthritis: A Case-Control StudyQ60689128
Renal cell carcinoma in New Zealand: a national survival studyQ72308380
Functional analysis of a mutation occurring between the two in-frame AUG codons of human angiotensinogenQ73236814
Is A163G polymorphism in the osteoprotegerin gene associated with heel velocity of sound in postmenopausal women?Q80691857
Association between osteoprotegerin (OPG), receptor activator of nuclear factor-kappaB (RANK), and RANK ligand (RANKL) gene polymorphisms and circulating OPG, soluble RANKL levels, and bone mineral density in Korean postmenopausal womenQ80712478
Expression of receptor activator of nuclear factor-kappaB is inversely correlated with metastatic phenotype in breast carcinomaQ81321200
Osteoprotegerin genetic polymorphisms and age of symptom onset in ankylosing spondylitisQ82047826
P407language of work or nameEnglishQ1860
P304page(s)40
P577publication date2013-01-31
P1433published inBMC CancerQ326300
P1476titleGenetic polymorphism of the OPG gene associated with breast cancer
P478volume13

Reverse relations

cites work (P2860)
Q35133898Evaluation of rs3102735 and rs2073617 Osteoprotegerin Gene Polymorphisms and the Risk of Childhood Acute lymphoblastic Leukemia in Zahedan Southeast Iran
Q48799956Genetic association and altered gene expression of osteoprotegerin in otosclerosis patients
Q34998448Osteoprotegerin expression in triple-negative breast cancer cells promotes metastasis
Q28081803Osteoprotegerin in breast cancer: beyond bone remodeling
Q26748804Osteoprotegerin rich tumor microenvironment: implications in breast cancer
Q92134531Osteoprotegerin: Relationship to Breast Cancer Risk and Prognosis
Q42013702Polymorphisms in the RANK/RANKL genes and their effect on bone specific prognosis in breast cancer patients
Q33895612RANK rs1805034 T>C polymorphism is associated with susceptibility of esophageal cancer in a Chinese population
Q53807792The association between RANKL and Osteoprotegerin gene polymorphisms with breast cancer.
Q37520235The prognostic role of RANK SNP rs34945627 in breast cancer patients with bone metastases.

Search more.