Vascular endothelial growth factor up-regulates expression of receptor activator of NF-kappa B (RANK) in endothelial cells. Concomitant increase of angiogenic responses to RANK ligand

scientific article published on 31 July 2003

Vascular endothelial growth factor up-regulates expression of receptor activator of NF-kappa B (RANK) in endothelial cells. Concomitant increase of angiogenic responses to RANK ligand is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M300539200
P698PubMed publication ID12893832

P50authorYong Song GhoQ87855760
Young-Yun KongQ89294464
P2093author name stringIl-Jun Kang
Young-Mi Kim
Soo-Young Lee
Young-Myeong Kim
Young-Guen Kwon
Jeong-Ki Min
Eok-Cheon Kim
P2860cites workOsteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
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The fms-like tyrosine kinase, a receptor for vascular endothelial growth factorQ24328901
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
RANK is essential for osteoclast and lymph node developmentQ24598872
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligandQ24653311
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland developmentQ28142247
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-SrcQ28142620
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by RasQ28238120
The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptorQ28285539
Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cellsQ28375565
Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endotheliumQ28512027
High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesisQ28594191
Angiogenesis in cancer, vascular, rheumatoid and other diseaseQ29547165
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesisQ29547178
Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteriaQ29616614
Transformation of mammalian cells by constitutively active MAP kinase kinaseQ29618686
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligandQ29619331
Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cellsQ31660362
Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-SrcQ33871655
Angiogenesis and bone growthQ34204716
TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factorQ36380989
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolismQ37108966
Vasculotropin/vascular endothelial growth factor induces differentiation in cultured osteoblastsQ38310846
Osteolysis and cancerQ39946675
Regulation of osteoclastogenesis and RANK expression by TGF-beta1.Q40778414
Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclastsQ40879592
Vascular endothelial growth factor governs endothelial nitric-oxide synthase expression via a KDR/Flk-1 receptor and a protein kinase C signaling pathwayQ40919226
Role of osteoblasts in hormonal control of bone resorption—A hypothesisQ41551873
Molecular mechanisms of blood vessel formationQ41560712
HMEC-1: establishment of an immortalized human microvascular endothelial cell lineQ41592068
VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formationQ41672985
Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorptionQ41772601
VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cellsQ42815794
An inhibitory role of the phosphatidylinositol 3-kinase-signaling pathway in vascular endothelial growth factor-induced tissue factor expressionQ43668422
TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cellsQ43821708
Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.Q46288581
Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesisQ73684776
Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokinesQ74269794
The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signalingQ77206124
Vascular endothelial growth factor activates nuclear factor-kappaB and induces monocyte chemoattractant protein-1 in bovine retinal endothelial cellsQ77759136
Cartilage to bone--angiogenesis leads the wayQ77890101
Immunolocalisation of vascular endothelial growth factor (VEGF) in human neonatal growth plate cartilageQ78121264
P433issue41
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
NF-κBQ411114
P1104number of pages10
P304page(s)39548-39557
P577publication date2003-07-31
P1433published inJournal of Biological ChemistryQ867727
P1476titleVascular endothelial growth factor up-regulates expression of receptor activator of NF-kappa B (RANK) in endothelial cells. Concomitant increase of angiogenic responses to RANK ligand
P478volume278

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