A directional switch of integrin signalling and a new anti-thrombotic strategy

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A directional switch of integrin signalling and a new anti-thrombotic strategy is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1007802561
P356DOI10.1038/NATURE12613
P932PMC publication ID3823815
P698PubMed publication ID24162846
P5875ResearchGate publication ID258103582

P50authorBo ShenQ54557826
P2093author name stringXiaoping Du
Aleksandra Stojanovic-Terpo
Jaehyung Cho
Kelly A O'Brien
Kyungho Kim
M Keegan Delaney
Stephen C-T Lam
Xiaojuan Zhao
P2860cites workStructural basis of integrin activation by talinQ24292977
Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeletonQ24293554
Integrins: bidirectional, allosteric signaling machinesQ27860700
Risk of bleeding complications with antiplatelet agents: meta-analysis of 338,191 patients enrolled in 50 randomized controlled trialsQ28166614
Integrins: dynamic scaffolds for adhesion and signaling in plateletsQ28267584
Kindlin-3 is essential for integrin activation and platelet aggregationQ28595084
Talin Binding to Integrin ß Tails: A Final Common Step in Integrin ActivationQ29617809
Integrin signalling in directed cell migration.Q30441276
Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of β3 integrinsQ30521428
Anti-GPIIb/IIIa drugs: current strategies and future directionsQ33338413
G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signalingQ33743722
Stimulatory roles of nitric-oxide synthase 3 and guanylyl cyclase in platelet activationQ34448738
Talin-dependent integrin activation is required for fibrin clot retraction by plateletsQ34667580
An important role for Akt3 in platelet activation and thrombosisQ35483767
A molecular switch that controls cell spreading and retractionQ36119672
Talin is required for integrin-mediated platelet function in hemostasis and thrombosisQ36294415
Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signalingQ36323239
Molecular mechanism of inside-out integrin regulationQ37903927
Inside-out, outside-in, and inside-outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction.Q38043667
Kindlin-2 (Mig-2): a co-activator of beta3 integrins.Q39985157
The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activationQ42131574
ADP-stimulated activation of Akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3β.Q42326649
Structural basis for the autoinhibition of talin in regulating integrin activationQ42410877
Sterically stabilized phospholipid mixed micelles: in vitro evaluation as a novel carrier for water-insoluble drugsQ44361240
Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa).Q44645544
Specification of the direction of adhesive signaling by the integrin beta cytoplasmic domainQ46171254
Conformational changes in fibrinogen elicited by its interaction with platelet membrane glycoprotein GPIIb-IIIaQ46619536
Identification of a Talin-binding Site in the Integrin β3Subunit Distinct from the NPLY Regulatory Motif of Post-ligand Binding FunctionsQ55920446
1-Pyrenyldiazomethane as a fluorescent labeling reagent for liquid chromatographic determination of carboxylic acidsQ68056266
Interaction of normal, thrombasthenic, and Bernard-Soulier platelets with immobilized fibrinogen: defective platelet-fibrinogen interaction in thrombastheniaQ71493148
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P4510describes a project that usesImageJQ1659584
P433issue7474
P407language of work or nameEnglishQ1860
P304page(s)131-135
P577publication date2013-10-27
P1433published inNatureQ180445
P1476titleA directional switch of integrin signalling and a new anti-thrombotic strategy
P478volume503

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cites work (P2860)
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