| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.NEURON.2014.01.013 |
| P8608 | Fatcat ID | release_ohf473bkxnhyxc3b2i7welywlu |
| P932 | PMC publication ID | 3978641 |
| P698 | PubMed publication ID | 24607225 |
| P5875 | ResearchGate publication ID | 260644680 |
| P50 | author | Laura Ferraiuolo | Q41574303 |
| P2093 | author name string | Brian K Kaspar | |
| Denis C Guttridge | |||
| Phillip G Popovich | |||
| Kevin D Foust | |||
| Katherine J Ladner | |||
| Leah Schmelzer | |||
| Lyndsey Braun | |||
| Jonathan P Godbout | |||
| Carlos J Miranda | |||
| Amanda M Haidet-Phillips | |||
| Adam K Bevan | |||
| Ashley E Frakes | |||
| P2860 | cites work | NF-kappaB regulates spatial memory formation and synaptic plasticity through protein kinase A/CREB signaling | Q24544118 |
| Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model | Q24631645 | ||
| Exploring the full spectrum of macrophage activation | Q24653754 | ||
| Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis | Q28131805 | ||
| Involvement of the pro-oncoprotein TLS (translocated in liposarcoma) in nuclear factor-kappa B p65-mediated transcription as a coactivator | Q28208385 | ||
| NF-kappaB signalling regulates the growth of neural processes in the developing PNS and CNS | Q28237759 | ||
| Roles for NF-kappaB in nerve cell survival, plasticity, and disease | Q28290234 | ||
| Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons | Q28298056 | ||
| Control of synaptic strength by glial TNFalpha | Q28570361 | ||
| Shared principles in NF-kappaB signaling | Q29547234 | ||
| Missing pieces in the NF-kappaB puzzle | Q29547864 | ||
| Mutations of optineurin in amyotrophic lateral sclerosis | Q29614836 | ||
| Directed differentiation of embryonic stem cells into motor neurons | Q29616200 | ||
| Regulation and function of NF-kappaB transcription factors in the immune system | Q29616427 | ||
| Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord | Q29619388 | ||
| Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis | Q29619430 | ||
| Onset and progression in inherited ALS determined by motor neurons and microglia | Q29619515 | ||
| Microglial physiology: unique stimuli, specialized responses | Q29620417 | ||
| Neuronal I kappa B kinase beta protects mice from autoimmune encephalomyelitis by mediating neuroprotective and immunosuppressive effects in the central nervous system | Q33893135 | ||
| Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits | Q34064405 | ||
| Astroglial inhibition of NF-κB does not ameliorate disease onset and progression in a mouse model for amyotrophic lateral sclerosis (ALS) | Q34698706 | ||
| A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model | Q34746889 | ||
| Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice | Q34988159 | ||
| Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis | Q34992177 | ||
| Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis | Q35094527 | ||
| Astrocytes from familial and sporadic ALS patients are toxic to motor neurons | Q35206666 | ||
| Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue | Q35830662 | ||
| Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS. | Q36190713 | ||
| Deletion of galectin-3 exacerbates microglial activation and accelerates disease progression and demise in a SOD1(G93A) mouse model of amyotrophic lateral sclerosis | Q36373508 | ||
| I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss | Q36402985 | ||
| Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS | Q37393810 | ||
| NF-kappaB in the nervous system | Q37412663 | ||
| Microglia in ALS: the good, the bad, and the resting | Q37592030 | ||
| Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease | Q37846934 | ||
| Review: microglia of the aged brain: primed to be activated and resistant to regulation | Q38049597 | ||
| Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways | Q38330282 | ||
| A new method to isolate microglia from adult mice and culture them for an extended period of time | Q39748715 | ||
| Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells | Q39910905 | ||
| Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation | Q39910909 | ||
| Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition | Q40707709 | ||
| Aging brain microenvironment decreases hippocampal neurogenesis through Wnt-mediated survivin signaling | Q41761592 | ||
| Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes | Q42739394 | ||
| Concurrence of multiple sclerosis and amyotrophic lateral sclerosis in patients with hexanucleotide repeat expansions of C9ORF72. | Q43584106 | ||
| Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study. | Q44824012 | ||
| In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-kappa B activation using a novel gene-targeted enhanced GFP reporter gene mouse | Q44987441 | ||
| Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism | Q45081990 | ||
| Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice | Q46254778 | ||
| A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. | Q47882897 | ||
| Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. | Q47951637 | ||
| Astroglial nuclear factor-kappaB regulates learning and memory and synaptic plasticity in female mice | Q48378417 | ||
| hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo | Q48736877 | ||
| Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB. | Q48906070 | ||
| Generation and characterization of MacGreen mice, the Cfs1r-EGFP transgenic mice. | Q50503990 | ||
| Immune system alterations in sporadic amyotrophic lateral sclerosis patients suggest an ongoing neuroinflammatory process. | Q51754875 | ||
| Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration. | Q52544555 | ||
| Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB | Q64381570 | ||
| IKKβ Is Required for Peripheral B Cell Survival and Proliferation | Q73299772 | ||
| Survival in a transgenic model of FALS is independent of iNOS expression | Q74377449 | ||
| Immune reactivity in a mouse model of familial ALS correlates with disease progression | Q74601938 | ||
| Absence of tumor necrosis factor-alpha does not affect motor neuron disease caused by superoxide dismutase 1 mutations | Q79323190 | ||
| Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia | Q80445359 | ||
| Is prostaglandin E(2) a pathogenic factor in amyotrophic lateral sclerosis? | Q83163530 | ||
| Nuclear factor κ B expression in patients with sporadic amyotrophic lateral sclerosis and hereditary amyotrophic lateral sclerosis with optineurin mutations | Q84521647 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | amyotrophic lateral sclerosis | Q206901 |
| NF-κB | Q411114 | ||
| microglia | Q1622829 | ||
| P304 | page(s) | 1009-1023 | |
| P577 | publication date | 2014-03-01 | |
| P1433 | published in | Neuron | Q3338676 |
| P1476 | title | Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis | |
| P478 | volume | 81 |
| Q64265433 | A Combination of Intrathecal and Intramuscular Application of Human Mesenchymal Stem Cells Partly Reduces the Activation of Necroptosis in the Spinal Cord of SOD1 Rats |
| Q91811620 | A Therapeutic Strategy for Alzheimer's Disease Focused on Immune-inflammatory Modulation |
| Q42611700 | A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models |
| Q28080614 | A perspective on stem cell modeling of amyotrophic lateral sclerosis |
| Q88701768 | A stocked toolbox for understanding the role of astrocytes in disease |
| Q38880527 | A20 in Multiple Sclerosis and Parkinson's Disease: Clue to a Common Dysregulation of Anti-Inflammatory Pathways? |
| Q36548825 | ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function |
| Q28553464 | ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis |
| Q52584458 | Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated Microglia. |
| Q58701384 | Acetylation state of RelA modulated by epigenetic drugs prolongs survival and induces a neuroprotective effect on ALS murine model |
| Q37196234 | Actions of the antihistaminergic clemastine on presymptomatic SOD1-G93A mice ameliorate ALS disease progression. |
| Q37620170 | Additive amelioration of ALS by co-targeting independent pathogenic mechanisms |
| Q30843477 | Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model |
| Q42281031 | Agonists for G-protein-coupled receptor 84 (GPR84) alter cellular morphology and motility but do not induce pro-inflammatory responses in microglia |
| Q41124218 | Anesthetic isoflurane attenuates activated microglial cytokine-induced VSC4.1 motoneuronal apoptosis |
| Q28078651 | Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS |
| Q41231187 | Astrocytes drive upregulation of the multidrug resistance transporter ABCB1 (P-Glycoprotein) in endothelial cells of the blood-brain barrier in mutant superoxide dismutase 1-linked amyotrophic lateral sclerosis |
| Q48144330 | Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha |
| Q90424918 | Astrocytic NF-κB brings the best and worst out of microglia |
| Q63739888 | Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration |
| Q39432638 | Autophagy in neurodegenerative diseases: pathogenesis and therapy. |
| Q64101663 | BRD4 inhibition attenuates inflammatory response in microglia and facilitates recovery after spinal cord injury in rats |
| Q41977590 | Benfotiamine upregulates antioxidative system in activated BV-2 microglia cells. |
| Q36909735 | Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. |
| Q51371013 | C9orf72 plays a central role in Rab GTPase-dependent regulation of autophagy. |
| Q92508814 | CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS |
| Q36898459 | CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves |
| Q61052224 | Ca-activated K channels modulate microglia affecting motor neuron survival in hSOD1 mice |
| Q48140499 | Can Astrocytes Be a Target for Precision Medicine? |
| Q64259754 | Cellular Specificity of NF-κB Function in the Nervous System |
| Q92643501 | Central nervous system regeneration is driven by microglia necroptosis and repopulation |
| Q60959815 | Challenges and Future Prospects on 3D Modeling of the Neuromuscular Circuit |
| Q55263095 | Circadian Rhythm Dysfunction Accelerates Disease Progression in a Mouse Model With Amyotrophic Lateral Sclerosis. |
| Q89599705 | Combined intramuscular and intraspinal transplant of bone marrow cells improves neuromuscular function in the SOD1G93A mice |
| Q58794925 | Compensatory Expression of Nur77 and Nurr1 Regulates NF-B-Dependent Inflammatory Signaling in Astrocytes |
| Q47255098 | Concise Review: The Cellular Conspiracy of Amyotrophic Lateral Sclerosis |
| Q60632864 | Cortical Neurotoxic Astrocytes with Early ALS Pathology and miR-146a Deficit Replicate Gliosis Markers of Symptomatic SOD1G93A Mouse Model |
| Q41701081 | Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. |
| Q47386934 | DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice. |
| Q30279070 | Dealing with Danger in the CNS: The Response of the Immune System to Injury |
| Q39004348 | Decoding ALS: from genes to mechanism. |
| Q34983540 | Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex |
| Q48134620 | Detection of the Cyanotoxins L-BMAA Uptake and Accumulation in Primary Neurons and Astrocytes |
| Q89287843 | Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia |
| Q93140574 | Dexmedetomidine protects aged rats from postoperative cognitive dysfunction by alleviating hippocampal inflammation |
| Q35645195 | Dietary Vitamin D3 Restriction Exacerbates Disease Pathophysiology in the Spinal Cord of the G93A Mouse Model of Amyotrophic Lateral Sclerosis |
| Q90049756 | Different Approaches to Modulation of Microglia Phenotypes After Spinal Cord Injury |
| Q38322767 | Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases |
| Q48141250 | Differential contribution of microglia and monocytes in neurodegenerative diseases. |
| Q58795408 | Differentiation of Glial Cells From hiPSCs: Potential Applications in Neurological Diseases and Cell Replacement Therapy |
| Q36184638 | Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways |
| Q48281779 | Downregulated Glia Interplay and Increased miRNA-155 as Promising Markers to Track ALS at an Early Stage |
| Q52725603 | Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons. |
| Q39650158 | ESE1 is Associated with Neuronal Apoptosis in Lipopolysaccharide Induced Neuroinflammation |
| Q49530211 | Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa |
| Q35064952 | Early-stage treatment with Withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral sclerosis |
| Q26797399 | Elusive roles for reactive astrocytes in neurodegenerative diseases |
| Q64087452 | Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS |
| Q90194187 | Enhanced Function and Overexpression of Metabotropic Glutamate Receptors 1 and 5 in the Spinal Cord of the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis during Disease Progression |
| Q47161931 | Etiogenic factors present in the cerebrospinal fluid from amyotrophic lateral sclerosis patients induce predominantly pro-inflammatory responses in microglia |
| Q38752410 | Exosomes from NSC-34 Cells Transfected with hSOD1-G93A Are Enriched in miR-124 and Drive Alterations in Microglia Phenotype. |
| Q96303459 | Exploring Sphingolipid Implications in Neurodegeneration |
| Q38985401 | Far beyond the motor neuron: the role of glial cells in amyotrophic lateral sclerosis |
| Q101403125 | Female sex mitigates motor and behavioural phenotypes in TDP-43Q331K knock-in mice |
| Q39561307 | Fingolimod: A Disease-Modifier Drug in a Mouse Model of Amyotrophic Lateral Sclerosis. |
| Q91920787 | Gamma secretase orthologs are required for lysosomal activity and autophagic degradation in Dictyostelium discoideum, independent of PSEN (presenilin) proteolytic function |
| Q38240820 | Genetic targeting of microglia |
| Q38700229 | Glia-neuron interactions in neurological diseases: Testing non-cell autonomy in a dish |
| Q92813735 | Glial Cells-The Strategic Targets in Amyotrophic Lateral Sclerosis Treatment |
| Q64100324 | Glial Contribution to Excitatory and Inhibitory Synapse Loss in Neurodegeneration |
| Q64257932 | Glial Control of Synapse Number in Healthy and Diseased Brain |
| Q38214532 | Glial cells in amyotrophic lateral sclerosis |
| Q35818695 | Glycosphingolipids are modulators of disease pathogenesis in amyotrophic lateral sclerosis |
| Q38630044 | HSPB1 mutations causing hereditary neuropathy in humans disrupt non-cell autonomous protection of motor neurons |
| Q39037865 | High content analysis in amyotrophic lateral sclerosis |
| Q47142356 | Histamine Regulates the Inflammatory Profile of SOD1-G93A Microglia and the Histaminergic System Is Dysregulated in Amyotrophic Lateral Sclerosis |
| Q90295077 | Histaminergic transmission slows progression of amyotrophic lateral sclerosis |
| Q40962491 | IL-10 Controls Early Microglial Phenotypes and Disease Onset in ALS Caused by Misfolded Superoxide Dismutase 1. |
| Q46245616 | Immunoglobulins G from Sera of Amyotrophic Lateral Sclerosis Patients Induce Oxidative Stress and Upregulation of Antioxidative System in BV-2 Microglial Cell Line |
| Q47153099 | In vivo genome editing improves motor function and extends survival in a mouse model of ALS. |
| Q64096028 | Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death |
| Q35274780 | Induction of COX-2-PGE2 synthesis by activation of the MAPK/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia |
| Q93346244 | Inflammation in ALS/FTD pathogenesis |
| Q40768273 | Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration. |
| Q38223011 | Innate immune activation in neurodegenerative disease |
| Q52731929 | Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis. |
| Q36934383 | Intraperitoneally administered IgG from patients with amyotrophic lateral sclerosis or from an immune-mediated goat model increase the levels of TNF-α, IL-6, and IL-10 in the spinal cord and serum of mice. |
| Q38592446 | Is membrane homeostasis the missing link between inflammation and neurodegenerative diseases? |
| Q97904894 | Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model |
| Q90391063 | LanCL1 promotes motor neuron survival and extends the lifespan of amyotrophic lateral sclerosis mice |
| Q52645967 | Limitations and Challenges in Modeling Diseases Involving Spinal Motor Neuron Degeneration in Vitro. |
| Q90219469 | Location of neonatal microglia drives small extracellular vesicles content and biological functions in vitro |
| Q64087393 | Loss of CREST leads to neuroinflammatory responses and ALS-like motor defects in mice |
| Q89947846 | Loss of angiogenin function is related to earlier ALS onset and a paradoxical increase in ALS duration |
| Q37549540 | M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b |
| Q30277241 | Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis |
| Q42708747 | Mesenchymal Stem Cells Modulate the Functional Properties of Microglia via TGF-β Secretion. |
| Q89963834 | Metabolic Regulation of Glial Phenotypes: Implications in Neuron-Glia Interactions and Neurological Disorders |
| Q41517777 | MicroRNA-125b regulates microglia activation and motor neuron death in ALS. |
| Q39454075 | Microglia and C9orf72 in neuroinflammation and ALS and frontotemporal dementia |
| Q38227727 | Microglia and inflammation: conspiracy, controversy or control? |
| Q38692790 | Microglia antioxidant systems and redox signalling |
| Q27009559 | Microglia centered pathogenesis in ALS: insights in cell interconnectivity |
| Q91786444 | Microglia in neurodegeneration |
| Q27317371 | Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke. |
| Q49789449 | Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy. |
| Q38685760 | Modulators of microglia: a patent review |
| Q33665800 | Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis |
| Q38521270 | N-Palmitoylethanolamine and Neuroinflammation: a Novel Therapeutic Strategy of Resolution |
| Q26827634 | NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair? |
| Q89013068 | NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS |
| Q91967451 | NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma |
| Q47763288 | NLRP3 Inflammasome Activation in a Transgenic Amyotrophic Lateral Sclerosis Model |
| Q98464779 | Neuroimmune System as a Driving Force for Plasticity Following CNS Injury |
| Q49808096 | Neuroinflammation in Alzheimer's Disease: Pleiotropic Roles for Cytokines and Neuronal Pentraxins |
| Q26776339 | Neuroinflammation in motor neuron disease |
| Q35529701 | Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis |
| Q60917211 | Neuropathology in intrauterine growth restricted newborn piglets is associated with glial activation and proinflammatory status in the brain |
| Q38701237 | New In Vitro Models to Study Amyotrophic Lateral Sclerosis |
| Q42284681 | Novel miR-b2122 regulates several ALS-related RNA-binding proteins. |
| Q37369313 | Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism |
| Q49231105 | Omega-3 Hastens and Omega-6 Delays the Progression of Neuropathology in a Murine Model of Familial ALS. |
| Q34920837 | Opposing roles of p38 and JNK in a Drosophila model of TDP-43 proteinopathy reveal oxidative stress and innate immunity as pathogenic components of neurodegeneration |
| Q97884465 | Oxidative Stress and Neuroinflammation Potentiate Each Other to Promote Progression of Dopamine Neurodegeneration |
| Q55347487 | PYNOD reduces microglial inflammation and consequent neurotoxicity upon lipopolysaccharides stimulation. |
| Q36841629 | Pathway Analysis Revealed Potential Diverse Health Impacts of Flavonoids that Bind Estrogen Receptors |
| Q96953340 | Peripheral and Central Nervous System Immune Response Crosstalk in Amyotrophic Lateral Sclerosis |
| Q36123997 | Phenotype-dependent alteration of pathways and networks reveals a pure synergistic mechanism for compounds treating mouse cerebral ischemia |
| Q94450925 | Potential of activated microglia as a source of dysregulated extracellular microRNAs contributing to neurodegeneration in amyotrophic lateral sclerosis |
| Q38841488 | Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification. |
| Q35978121 | Prevention of the degeneration of human dopaminergic neurons in an astrocyte co-culture system allowing endogenous drug metabolism |
| Q34669342 | Randomized phase 2 trial of NP001-a novel immune regulator: Safety and early efficacy in ALS. |
| Q41871282 | Receptor for Advanced Glycation End Products and its Inflammatory Ligands are Upregulated in Amyotrophic Lateral Sclerosis. |
| Q36955096 | Reduction of cytosolic phospholipase A2α upregulation delays the onset of symptoms in SOD1G93A mouse model of amyotrophic lateral sclerosis |
| Q91835943 | Reduction of ephrin-A5 aggravates disease progression in amyotrophic lateral sclerosis |
| Q92553022 | Regional differences in the inflammatory and heat shock response in glia: implications for ALS |
| Q38505120 | Regulation of the Neurodegenerative Process Associated to Parkinson's Disease by CD4+ T-cells |
| Q57162410 | Repeated Intrathecal Mesenchymal Stem Cells for Amyotrophic Lateral Sclerosis |
| Q30355125 | Report on the 3rd Ottawa International Conference on Neuromuscular Biology, Disease and Therapy - September 24-26, 2015, Ottawa, Canada. |
| Q36734551 | Reverse engineering human neurodegenerative disease using pluripotent stem cell technology |
| Q47404070 | Review: Impact of Helicobacter pylori on Alzheimer's disease: What do we know so far? |
| Q89589416 | Role of Nuclear factor kappa B (NF-κB) Signalling in Neurodegenerative Diseases: An Mechanistic Approach |
| Q37133751 | SCISSOR-Spinal Cord Injury Study on Small molecule-derived Rho inhibition: a clinical study protocol |
| Q48384156 | Selective induction of P-glycoprotein at the CNS barriers during symptomatic stage of an ALS animal model |
| Q49026083 | Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis |
| Q36483870 | Signaling pathways regulating neuron-glia interaction and their implications in Alzheimer's disease |
| Q92069599 | Small-Molecule Lysophosphatidic Acid Receptor 5 (LPAR5) Antagonists: Versatile Pharmacological Tools to Regulate Inflammatory Signaling in BV-2 Microglia Cells |
| Q34463760 | Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration |
| Q89581381 | TNF receptor-associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation |
| Q40409465 | Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis. |
| Q27340206 | Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice. |
| Q45931909 | The Cholinergic System Modulates Memory and Hippocampal Plasticity via Its Interactions with Non-Neuronal Cells. |
| Q41107984 | The Dual Role of Microglia in ALS: Mechanisms and Therapeutic Approaches |
| Q41447335 | The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases. |
| Q94561279 | The Peripheral Immune System and Amyotrophic Lateral Sclerosis |
| Q36284525 | The Regulatory Machinery of Neurodegeneration in In Vitro Models of Amyotrophic Lateral Sclerosis |
| Q61448143 | The Relevancy of Data Regarding the Metabolism of Iron to Our Understanding of Deregulated Mechanisms in ALS; Hypotheses and Pitfalls |
| Q64235442 | The Specific Inhibition of SOD1 Selectively Promotes Apoptosis of Cancer Cells via Regulation of the ROS Signaling Network |
| Q89645812 | The clinical trial landscape in amyotrophic lateral sclerosis-Past, present, and future |
| Q83600762 | The deletion of mutant SOD1 via CRISPR/Cas9/sgRNA prolongs survival in an amyotrophic lateral sclerosis mouse model |
| Q38636765 | The established and emerging roles of astrocytes and microglia in amyotrophic lateral sclerosis and frontotemporal dementia |
| Q58608310 | The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex |
| Q38955367 | The non-cell-autonomous component of ALS: new in vitro models and future challenges. |
| Q40080281 | The role of the immunoproteasome in interferon-γ-mediated microglial activation |
| Q89460412 | The α7 nicotinic acetylcholine receptor positive allosteric modulator prevents lipopolysaccharide-induced allodynia, hyperalgesia and TNF-α in the hippocampus in mice |
| Q39271545 | Therapeutic Strategies Under Development Targeting Inflammatory Mechanisms in Amyotrophic Lateral Sclerosis |
| Q41573357 | Toll-Like Receptor-4 Inhibitor TAK-242 Attenuates Motor Dysfunction and Spinal Cord Pathology in an Amyotrophic Lateral Sclerosis Mouse Model |
| Q90042596 | Transcriptome analysis of the effect of C-C chemokine receptor 5 deficiency on cell response to Toxoplasma gondii in brain cells |
| Q36394283 | Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS. |
| Q47951993 | Traumatic Brain Injury Results in Cellular, Structural and Functional Changes Resembling Motor Neuron Disease. |
| Q30671325 | Ubiquilin-2 drives NF-κB activity and cytosolic TDP-43 aggregation in neuronal cells. |
| Q33586011 | Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration. |
Search more.