The essential N terminus of the Pta1 scaffold protein is required for snoRNA transcription termination and Ssu72 function but is dispensable for pre-mRNA 3'-end processing.

scientific article

The essential N terminus of the Pta1 scaffold protein is required for snoRNA transcription termination and Ssu72 function but is dispensable for pre-mRNA 3'-end processing. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.01514-08
P932PMC publication ID2663318
P698PubMed publication ID19188448

P50authorBadri Nath SinghQ51682867
P2093author name stringClaire Moore
Michael Hampsey
Mohamed A Ghazy
Xiaoyuan He
P2860cites workFunctional organization of the yeast proteome by systematic analysis of protein complexesQ24292209
BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.Q24302667
Symplekin and multiple other polyadenylation factors participate in 3'-end maturation of histone mRNAsQ24537115
Complex protein interactions within the human polyadenylation machinery identify a novel componentQ24554306
Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeastQ27930053
Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursorQ27930178
Nuclear mRNA surveillance in THO/sub2 mutants is triggered by inefficient polyadenylationQ27931769
Coupling termination of transcription to messenger RNA maturation in yeast.Q52529973
A transcription-independent role for TFIIB in gene looping.Q53530055
Regulation of yeast mRNA 3' end processing by phosphorylation.Q53658895
Purification of the Saccharomyces cerevisiae cleavage/polyadenylation factor I. Separation into two components that are required for both cleavage and polyadenylation of mRNA 3' endsQ71742752
Growth-related changes in phosphorylation of yeast RNA polymerase IIQ74192542
PTA1, an essential gene of Saccharomyces cerevisiae affecting pre-tRNA processingQ27932158
Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I.Q27933038
Fip1 regulates the activity of Poly(A) polymerase through multiple interactionsQ27933118
Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription terminationQ27933119
Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-endsQ27933144
Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA.Q27933903
Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear exportQ27934522
A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factorQ27935985
Ssu72 Is an RNA polymerase II CTD phosphataseQ27936648
RNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcriptsQ27936766
A role for SSU72 in balancing RNA polymerase II transcription elongation and terminationQ27937178
Pti1p and Ref2p found in association with the mRNA 3' end formation complex direct snoRNA maturationQ27937796
Novel interactions of Saccharomyces cerevisiae type 1 protein phosphatase identified by single-step affinity purification and mass spectrometry.Q27937983
Functional interactions between the transcription and mRNA 3′ end processing machineries mediated by Ssu72 and Sub1Q27939095
Ssu72 protein mediates both poly(A)-coupled and poly(A)-independent termination of RNA polymerase II transcriptionQ27939641
Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeastQ28131604
5-Fluoroorotic acid as a selective agent in yeast molecular geneticsQ28131614
Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formationQ28258510
Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonucleaseQ28275724
The essential WD repeat protein Swd2 has dual functions in RNA polymerase II transcription termination and lysine 4 methylation of histone H3Q28776149
A unified theory of gene expressionQ29615022
A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombeQ31025627
Alternative polyadenylation: a twist on mRNA 3' end formationQ34013917
Symplekin and xGLD-2 are required for CPEB-mediated cytoplasmic polyadenylationQ34369092
The role of the Brr5/Ysh1 C-terminal domain and its homolog Syc1 in mRNA 3'-end processing in Saccharomyces cerevisiaeQ34411087
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
Eukaryotic mRNA 3' processing: a common means to different endsQ36303654
Protein factors in pre-mRNA 3'-end processing.Q37044967
A role for ubiquitin in the spliceosome assembly pathwayQ37332858
Regulation of poly(A) site choice of several yeast mRNAsQ39725288
A role for the CPF 3'-end processing machinery in RNAP II-dependent gene loopingQ40648979
Termination and pausing of RNA polymerase II downstream of yeast polyadenylation sitesQ41863936
Inactivation of the pre-mRNA cleavage and polyadenylation factor Pfs2 in fission yeast causes lethal cell cycle defectsQ41904654
Sumoylation modulates the assembly and activity of the pre-mRNA 3' processing complexQ42823824
Heat-inducible degron: a method for constructing temperature-sensitive mutants.Q45930863
The Glc7 phosphatase subunit of the cleavage and polyadenylation factor is essential for transcription termination on snoRNA genes.Q47068298
Nuclear polyadenylation factors recognize cytoplasmic polyadenylation elementsQ49106842
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectCleavage polyadenylation factor subunit PTI1 YGR156WQ27550290
Cleavage polyadenylation factor subunit CFT2 YLR115WQ27551166
Cleavage polyadenylation factor subunit YSH1 YLR277CQ27551287
RNA polymerase II subunit A C-terminal domain phosphatase YNL222WQ27551720
Cleavage polyadenylation factor subunit FIP1 YJR093CQ27552150
RNA-processing protein PTA1 YAL043CQ27552794
P304page(s)2296-2307
P577publication date2009-02-02
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleThe essential N terminus of the Pta1 scaffold protein is required for snoRNA transcription termination and Ssu72 function but is dispensable for pre-mRNA 3'-end processing
P478volume29

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