| P50 | author | John Lunec | Q90706188 |
| P2093 | author name string | Junfeng Liu | |
| | Yan Zhao | |
| | Bernard T Golding | |
| | Shafiq Ahmed | |
| | David R Newell | |
| | Roger J Griffin | |
| | Xiaohong Lu | |
| | Ian R Hardcastle | |
| | Christopher R Coxon | |
| | Andrey Zaytzev | |
| | Anna F Watson | |
| | Claire Hutton | |
| | Stephen Ojo | |
| | Tim J Blackburn | |
| P2860 | cites work | Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain | Q24314763 |
| | Mdm2 promotes the rapid degradation of p53 | Q24322597 |
| | MDMX: a novel p53-binding protein with some functional properties of MDM2 | Q24561971 |
| | Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization | Q27670558 |
| | Structure-based design of novel inhibitors of the MDM2-p53 interaction | Q27678657 |
| | Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development | Q27684199 |
| | Deconstruction of a Nutlin: Dissecting the Binding Determinants of a Potent Protein–Protein Interaction Inhibitor | Q27684203 |
| | Regulation of p53 stability by Mdm2 | Q27860744 |
| | Overview of the CCP4 suite and current developments | Q27860782 |
| | p53, the cellular gatekeeper for growth and division | Q27860990 |
| | Features and development of Coot | Q27861079 |
| | MDM2 interacts with MDMX through their RING finger domains | Q28142437 |
| | Amplification of a gene encoding a p53-associated protein in human sarcomas | Q28270924 |
| | The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation | Q28280958 |
| | On the mechanism of action of SJ-172550 in inhibiting the interaction of MDM4 and p53 | Q28484086 |
| | Microwave-Assisted Paal−Knorr Reaction. A Rapid Approach to Substituted Pyrroles and Furans | Q29035611 |
| | Live or let die: the cell's response to p53 | Q29547663 |
| | New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays | Q29615588 |
| | Regulating the p53 pathway: in vitro hypotheses, in vivo veritas | Q29615658 |
| | Small-molecule inhibitors of the MDM2-p53 protein-protein interaction based on an isoindolinone scaffold | Q33260048 |
| | Identification and characterization of the first small molecule inhibitor of MDMX | Q33524716 |
| | Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo | Q34480082 |
| | Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects | Q34623003 |
| | Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor | Q34979439 |
| | MDMX: from bench to bedside | Q36717697 |
| | MDM4 is a key therapeutic target in cutaneous melanoma | Q37096987 |
| | Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors | Q37249642 |
| | Mdm2 and MdmX inhibitors for the treatment of cancer: a patent review (2011-present). | Q38078456 |
| | Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties | Q39459414 |
| | Mdm2 association with p53 targets its ubiquitination | Q42824389 |
| | Novel ester and acid derivatives of the 1,5-diarylpyrrole scaffold as anti-inflammatory and analgesic agents. Synthesis and in vitro and in vivo biological evaluation | Q43230959 |
| | Analysis of chemical shift changes reveals the binding modes of isoindolinone inhibitors of the MDM2-p53 interaction | Q46286595 |
| | 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings. | Q46583972 |
| | Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery. | Q47440423 |
| | Tetrapropylammonium Perruthenate, Pr4N+RuO4 -, TPAP: A Catalytic Oxidant for Organic Synthesis | Q56016533 |
| | Discovery, synthesis, and biological evaluation of orally active pyrrolidone derivatives as novel inhibitors of p53-MDM2 protein-protein interaction | Q87418864 |
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | protein-protein interaction | Q896177 |
| P304 | page(s) | 1297-1304 | |
| P577 | publication date | 2013-07-29 | |
| P1433 | published in | MedChemComm | Q3303881 |
| P1476 | title | Diaryl- and triaryl-pyrrole derivatives: inhibitors of the MDM2-p53 and MDMX-p53 protein-protein interactions†Electronic supplementary information (ESI) available: Experimental details for compound synthesis, analytical data for all compounds and in | |
| P478 | volume | 4 | |