Identification of protein kinase inhibitors with a selective negative effect on the viability of Epstein-Barr virus infected B cell lines

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Identification of protein kinase inhibitors with a selective negative effect on the viability of Epstein-Barr virus infected B cell lines is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...995688M
P356DOI10.1371/JOURNAL.PONE.0095688
P932PMC publication ID3997413
P698PubMed publication ID24759913
P5875ResearchGate publication ID261838642

P50authorZoltán VargaQ60678028
P2093author name stringGyörgy Kéri
George Mosialos
László Őrfi
Zoltán Őrfi
Frigyes Waczek
Vassilis Mavromatidis
P2860cites workTargeting Src family kinases in anti-cancer therapies: turning promise into triumphQ27025646
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EBV LMP2A provides a surrogate pre-B cell receptor signal through constitutive activation of the ERK/MAPK pathwayQ33739672
Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latencyQ33784647
Epstein-Barr virus in Burkitt's lymphoma: a role for latent membrane protein 2AQ33794029
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Src family kinase inhibitor PP2 efficiently inhibits cervical cancer cell proliferation through down-regulating phospho-Src-Y416 and phospho-EGFR-Y1173Q53291157
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An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinkingQ35000168
Reducing the complexity of the transforming Epstein-Barr virus genome to 64 kilobase pairs.Q35832104
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Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activationQ36564433
Epstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytesQ36646940
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The signaling pathways of Epstein-Barr virus-encoded latent membrane protein 2A (LMP2A) in latency and cancer.Q37350748
Off-target effects of MEK inhibitorsQ37385007
Simvastatin induces apoptosis of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas.Q37415623
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Transcriptional cross-regulation of RUNX1 by RUNX3 in human B cells.Q38331064
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Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemiaQ39725899
Establishment in continuous culture of a new type of lymphocyte from a “burkitt-like” malignant lymphoma (line d.g.-75)Q40039870
Cutting edge: constitutive B cell receptor signaling is critical for basal growth of B lymphomaQ40284461
Activation of a ras-MAPK-dependent pathway by Epstein-Barr virus latent membrane protein 1 is essential for cellular transformationQ41068635
Expression of p56lck in B-cell neoplasiasQ41095204
Identification of MEK1 as a novel target for the treatment of neuropathic painQ42267806
Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signalsQ44664210
Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinasesQ45783522
A-770041, a novel and selective small-molecule inhibitor of Lck, prevents heart allograft rejectionQ46598536
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectEpstein–Barr virusQ6900
P304page(s)e95688
P577publication date2014-04-23
P1433published inPLOS OneQ564954
P1476titleIdentification of protein kinase inhibitors with a selective negative effect on the viability of Epstein-Barr virus infected B cell lines
P478volume9

Reverse relations

Q92128486Human DNA Virus Exploitation of the MAPK-ERK Cascadecites workP2860