review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0065-2776(05)87004-X |
P8608 | Fatcat ID | release_zxc6x3aoyzaupjdeamrb3w3mim |
P698 | PubMed publication ID | 16102573 |
P2093 | author name string | Kathryn Haskins | |
P2860 | cites work | Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes. | Q24679680 |
Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library | Q24804498 | ||
Integrins: bidirectional, allosteric signaling machines | Q27860700 | ||
Integrins: versatility, modulation, and signaling in cell adhesion | Q27860844 | ||
Interleukin-17 family and IL-17 receptors | Q28185677 | ||
Phenotypic analysis of antigen-specific T lymphocytes | Q28290058 | ||
Preferential production of interferon-gamma by CD4+ T cells expressing the homing receptor integrin alpha4/beta7 | Q28367021 | ||
Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes | Q28583729 | ||
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells | Q28585061 | ||
Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein | Q28589562 | ||
A diabetes-associated T-cell autoantigen maps to a telomeric locus on mouse chromosome 6. | Q30453976 | ||
Identification of MHC class II-restricted peptide ligands, including a glutamic acid decarboxylase 65 sequence, that stimulate diabetogenic T cells from transgenic BDC2.5 nonobese diabetic mice | Q30644510 | ||
Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library. | Q30763625 | ||
T cell response to preproinsulin I and II in the nonobese diabetic mouse | Q30844663 | ||
Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones | Q30872028 | ||
Tracking autoimmune T cells in diabetes | Q30982114 | ||
Autoantibodies and CD4 T cells target a beta cell retroviral envelope protein in non-obese diabetic mice | Q31029592 | ||
Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase | Q31131014 | ||
Increased islet antigen presentation leads to type-1 diabetes in mice with autoimmune susceptibility | Q47867708 | ||
T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes | Q47872045 | ||
Single-cell analysis of the murine chemokines MIP-1alpha, MIP-1beta, RANTES and ATAC/lymphotactin by flow cytometry. | Q52952880 | ||
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. | Q55066037 | ||
Identification of a -Cell-Specific HLA Class I Restricted Epitope in Type 1 Diabetes | Q58328327 | ||
Progression of autoimmune diabetes driven by avidity maturation of a T-cell population | Q58328335 | ||
T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins | Q59072743 | ||
Following a diabetogenic T cell from genesis through pathogenesis | Q70488192 | ||
Bone marrow abnormalities in the non-obese diabetic mouse | Q70608733 | ||
Organ-specific disease provoked by systemic autoimmunity | Q71838378 | ||
T helper cell subsets in insulin-dependent diabetes | Q72265872 | ||
An islet-homing NOD CD8+ cytotoxic T cell clone recognizes GAD65 and causes insulitis | Q73174046 | ||
Subsets of macrophages and dendritic cells in nonobese diabetic mouse pancreatic inflammatory infiltrates: correlation with the development of diabetes | Q73397999 | ||
GAD-about BDC2.5: Peptides that stimulate BDC2.5 T cells and inhibit IDDM | Q73407927 | ||
Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions | Q73567384 | ||
A glutamic acid decarboxylase 65-specific Th2 cell clone immunoregulates autoimmune diabetes in nonobese diabetic mice | Q73896300 | ||
Biochemical characterization of a beta cell membrane fraction antigenic for autoreactive T cell clones | Q73958439 | ||
Genetic control of diabetes progression | Q74045636 | ||
Nondepleting anti-CD4 has an immediate action on diabetogenic effector cells, halting their destruction of pancreatic beta cells | Q74108273 | ||
Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes | Q77192908 | ||
Islet cell membrane antigens activate diabetogenic CD4+ T-cells in the BB/Wor rat | Q77759108 | ||
Cellular and molecular changes accompanying the progression from insulitis to diabetes | Q77952302 | ||
Cellular immune response to phogrin in the NOD mouse: cloned T-cells cause destruction of islet transplants | Q78060357 | ||
Low expression of insulin in the thymus of non-obese diabetic mice | Q78631903 | ||
Diabetes incidence is unaltered in glutamate decarboxylase 65-specific TCR retrogenic nonobese diabetic mice: generation by retroviral-mediated stem cell gene transfer | Q80475644 | ||
Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes | Q46512140 | ||
Detection and characterization of T cells specific for BDC2.5 T cell-stimulating peptides. | Q47564253 | ||
Ex Vivo Analysis of Thymic CD4 T Cells in Nonobese Diabetic Mice with Tetramers Generated from I-Ag7/Class II-Associated Invariant Chain Peptide Precursors | Q47581749 | ||
Chemokines and T lymphocytes: more than an attraction | Q47713299 | ||
Comparison of a T cell clone and of T cells from a TCR transgenic mouse: TCR transgenic T cells specific for self-antigen are atypical | Q31839049 | ||
Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23) | Q33592891 | ||
Regional specialization in the mucosal immune system: primed cells do not always home along the same track | Q33650461 | ||
Lymphocyte trafficking and regional immunity. | Q33653665 | ||
Dissecting the role of CD4+ T cells in autoimmune diabetes through the use of TCR transgenic mice | Q33713280 | ||
IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes | Q33938806 | ||
Nanoscale organization of multiple GPI-anchored proteins in living cell membranes. | Q33976149 | ||
Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitus | Q34025467 | ||
MIP-1alpha, MIP-1beta, RANTES, and ATAC/lymphotactin function together with IFN-gamma as type 1 cytokines | Q34028418 | ||
It's insulin | Q34065086 | ||
Lymphocyte traffic control by chemokines | Q34139610 | ||
Alternative splicing controls myotonic dystrophy protein kinase structure, enzymatic activity, and subcellular localization | Q34219488 | ||
Characterization of the myotonic dystrophy region predicts multiple protein isoform-encoding mRNAs | Q34231532 | ||
T-cell receptor transgenic mice in the study of autoimmune diseases | Q34301532 | ||
Pancreatic islet-specific T-cell clones from nonobese diabetic mice | Q34313103 | ||
The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. | Q34452348 | ||
Expanding complexity in myotonic dystrophy | Q34485468 | ||
Cytokines and autoimmunity | Q34572227 | ||
Tracking T cells with tetramers: new tales from new tools | Q34632077 | ||
Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention. | Q34768674 | ||
Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood | Q34830048 | ||
T-cell activation: a multidimensional signaling network. | Q34858190 | ||
Autoreactive T cells in endocrine/organ-specific autoimmunity: why has progress been so slow? | Q35034684 | ||
MHC multimers: expanding the clinical toolkit. | Q35065291 | ||
Antigen-induced T1D in NOD mice | Q35130073 | ||
A comprehensive guide to antibody and T-cell responses in type 1 diabetes. | Q35583448 | ||
Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes | Q35602903 | ||
Interleukin-17: the missing link between T-cell accumulation and effector cell actions in rheumatoid arthritis? | Q35675887 | ||
T-cell receptor transgenic (TCR-Tg) mice from two diabetogenic CD4+ islet-antigen-specific T-cell clones | Q35677342 | ||
T-cell receptor-transgenic NOD mice: a reductionist approach to understand autoimmune diabetes | Q35677353 | ||
Integrins and T cell-mediated immunity | Q35698435 | ||
Beta cell apoptosis in T cell-mediated autoimmune diabetes | Q35905815 | ||
Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity | Q35919777 | ||
T cell receptor restriction of diabetogenic autoimmune NOD T cells | Q36049067 | ||
The clinical and biological relationship between Type II diabetes mellitus and Alzheimer's disease | Q36173253 | ||
T cell receptor V gene usage of islet beta cell-reactive T cells is not restricted in non-obese diabetic mice | Q36230116 | ||
Ly-6C regulates endothelial adhesion and homing of CD8(+) T cells by activating integrin-dependent adhesion pathways | Q36242077 | ||
Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells. | Q36353954 | ||
CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells. | Q36366075 | ||
Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes | Q36367942 | ||
In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha. | Q36368009 | ||
Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells. | Q36370525 | ||
A mechanism for the major histocompatibility complex-linked resistance to autoimmunity | Q36380664 | ||
Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice | Q36380895 | ||
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes | Q36400199 | ||
Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement | Q36526326 | ||
The identification of CD4+ T cell epitopes with dedicated synthetic peptide libraries | Q36586011 | ||
Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice | Q36678330 | ||
Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice | Q36736666 | ||
Intranasal administration of insulin peptide B: 9-23 protects NOD mice from diabetes | Q36796917 | ||
Peripheral T cell clones from NOD mice specific for GAD65 peptides: lack of islet responsiveness or diabetogenicity | Q36820923 | ||
T Cell Receptor Gene Polymorphisms Associated with Anti-Insulin, Autoimmune T Cells in Diabetes-Prone NOD Mice | Q36870393 | ||
Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes | Q37114100 | ||
Insulitis in transgenic mice expressing tumor necrosis factor beta (lymphotoxin) in the pancreas | Q37263532 | ||
GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice. | Q37376906 | ||
Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice | Q37384851 | ||
IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus | Q37518209 | ||
Islet-specific T-cell clones from nonobese diabetic mice express heterogeneous T-cell receptors. | Q37548447 | ||
The insulin secretory granule | Q38255435 | ||
HLA-DQ8-associated T cell responses to the diabetes autoantigen phogrin (IA-2 beta) in human prediabetes | Q40581535 | ||
Ly6C induces clustering of LFA-1 (CD11a/CD18) and is involved in subtype-specific adhesion of CD8 T cells | Q40675952 | ||
MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity | Q40790715 | ||
Regulatory and effector CD4 T cells in nonobese diabetic mice recognize overlapping determinants on glutamic acid decarboxylase and use distinct V beta genes | Q40826705 | ||
Induction of diabetes in nonobese diabetic mice by Th2 T cell clones from a TCR transgenic mouse | Q40895338 | ||
CD8 cytotoxic T-cell clone rapidly transfers autoimmune diabetes in very young NOD and MHC class I-compatible scid mice | Q41090515 | ||
Adhesion molecules in autoimmune disease | Q41133422 | ||
HLA-DR-restricted T cell lines from newly diagnosed type 1 diabetic patients specific for insulinoma and normal islet beta cell proteins: lack of reactivity to glutamic acid decarboxylase | Q41291890 | ||
Autoreactive T-cell clones from the nonobese diabetic mouse | Q41333085 | ||
T-cell epitope analysis on the autoantigen phogrin (IA-2beta) in the nonobese diabetic mouse | Q43687826 | ||
Paralytic autoimmune myositis develops in nonobese diabetic mice made Th1 cytokine-deficient by expression of an IFN-gamma receptor beta-chain transgene | Q44040421 | ||
Spontaneous peripheral T-cell responses to the IA-2beta (phogrin) autoantigen in young nonobese diabetic mice | Q44207015 | ||
Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone | Q44534362 | ||
Autoimmune diabetes and the circle of tolerance | Q44745115 | ||
GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes | Q44903844 | ||
T cells with multiple fine specificities are used by non-obese diabetic (NOD) mice in the response to GAD(524-543). | Q46506956 | ||
P304 | page(s) | 123-162 | |
P577 | publication date | 2005-01-01 | |
P1433 | published in | Advances in Immunology | Q15752932 |
P1476 | title | Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse | |
P478 | volume | 87 |
Q39210341 | A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis |
Q51350685 | An insulin-IAPP hybrid peptide is an endogenous antigen for CD4 T cells in the non-obese diabetic mouse. |
Q34508281 | An update on the use of NOD mice to study autoimmune (Type 1) diabetes |
Q37655229 | Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus |
Q37358987 | Autoimmune diabetes mellitus--much progress, but many challenges |
Q36954468 | B Cell in Autoimmune Diseases |
Q37613441 | CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes |
Q24605199 | Chromogranin A is an autoantigen in type 1 diabetes |
Q37274444 | Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic mice. |
Q30481754 | Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules |
Q36410759 | Diabetogenic T-cell clones recognize an altered peptide of chromogranin A. |
Q45174166 | Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse |
Q37597035 | Exosomes released by islet-derived mesenchymal stem cells trigger autoimmune responses in NOD mice |
Q92535485 | Hybrid insulin peptides are neo-epitopes for CD4 T cells in autoimmune diabetes |
Q33367125 | IL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanisms |
Q33712227 | Insulin as a key autoantigen in the development of type 1 diabetes |
Q35180093 | Islet amyloid polypeptide is a target antigen for diabetogenic CD4+ T cells |
Q35091388 | Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity |
Q38691482 | Mechanisms of autoimmunity in the non-obese diabetic mouse: effector/regulatory cell equilibrium during peak inflammation |
Q38660197 | Mechanisms of diabetic autoimmunity: I--the inductive interface between islets and the immune system at onset of inflammation |
Q59829524 | Modulation of diabetes in NOD mice by GAD65-specific monoclonal antibodies is epitope specific and accompanied by anti-idiotypic antibodies |
Q36047584 | Modulation of redox balance leaves murine diabetogenic TH1 T cells "LAG-3-ing" behind. |
Q37018598 | Novel autoantigens for diabetogenic CD4 T cells in autoimmune diabetes |
Q36945852 | Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion |
Q81553727 | Pathogenicity of T helper 2 T-cell clones from T-cell receptor transgenic non-obese diabetic mice is determined by tumour necrosis factor-alpha |
Q90601639 | Peptide mimotopes alter T cell function in cancer and autoimmunity |
Q35902878 | Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: Vβ13 as a therapeutic target and biomarker |
Q33331089 | Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells |
Q58233277 | Recent insights into CD4+T-cell specificity and function in Type 1 diabetes |
Q48293644 | Simultaneous Recognition of Allogeneic MHC and Cognate Autoantigen by Autoreactive T Cells in Transplant Rejection. |
Q41782901 | Status of autoimmune diabetes 20-year after generation of BDC2.5-TCR transgenic non-obese diabetic mouse |
Q37545537 | T Cell Repertoire Diversity Is Decreased in Type 1 Diabetes Patients |
Q47093542 | T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes |
Q37389695 | T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event |
Q36971881 | T cells interact with T cells via CD40-CD154 to promote autoimmunity in type 1 diabetes |
Q37758077 | The anti-insulin trimolecular complex in type 1 diabetes. |
Q34831727 | Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes |
Q34227916 | ZnT8-reactive T cells are weakly pathogenic in NOD mice but can participate in diabetes under inflammatory conditions |
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