An integrative genomic and epigenomic approach for the study of transcriptional regulation

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An integrative genomic and epigenomic approach for the study of transcriptional regulation is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2008PLoSO...3.1882F
P356DOI10.1371/JOURNAL.PONE.0001882
P932PMC publication ID2266992
P698PubMed publication ID18365023
P5875ResearchGate publication ID5487476

P50authorElisabeth PaiettaQ69071275
Peter H. WiernikQ100309276
Reid F ThompsonQ41312233
John GreallyQ42667137
P2093author name stringRoland D Green
Ari Melnick
Kenny Ye
Mark Reimers
Maria E Figueroa
Yushan Li
Jakob Fridriksson
Rebecca R Selzer
P2860cites workAberrant methylation and impaired expression of the p15(INK4b) cell cycle regulatory gene in chronic myelomonocytic leukemia (CMML).Q54773230
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Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasiaQ57240085
Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemiaQ78125085
Large-scale CpG methylation analysis identifies novel candidate genes and reveals methylation hotspots in acute lymphoblastic leukemiaQ38303652
Interactive exploration of microarray gene expression patterns in a reduced dimensional spaceQ39860879
hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start siteQ40185373
DNA methylation immediately adjacent to active histone marking does not silence transcription.Q40187418
Genome-wide profiling of CpG methylation identifies novel targets of aberrant hypermethylation in myeloid leukemiaQ40267029
Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin stateQ40296469
Triple analysis of the cancer epigenome: an integrated microarray system for assessing gene expression, DNA methylation, and histone acetylationQ40650614
Mapping global histone acetylation patterns to gene expressionQ44928696
CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomasQ45009128
Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomasQ46610612
Prognostically useful gene-expression profiles in acute myeloid leukemia.Q51999490
DNA methylation patterns and epigenetic memoryQ22065780
Translating the Histone CodeQ22065840
Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?Q22251049
Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometryQ24536837
Cluster analysis and display of genome-wide expression patternsQ24644463
The human genome browser at UCSCQ24672361
Comparative isoschizomer profiling of cytosine methylation: the HELP assayQ24685607
Quality assessment of microarrays: visualization of spatial artifacts and quantitation of regional biasesQ24815050
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphomaQ27824784
Worms gang up on bacteriaQ27860588
Molecular classification of cancer: class discovery and class prediction by gene expression monitoringQ27861072
Genomic maps and comparative analysis of histone modifications in human and mouseQ29614418
Methylation of histone H3 Lys 4 in coding regions of active genesQ29614680
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinomaQ29615026
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancerQ29615066
Gene silencing in cancer in association with promoter hypermethylationQ29617274
Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter bindingQ30308636
Correspondence analysis applied to microarray dataQ30659762
MADE4: an R package for multivariate analysis of gene expression dataQ30986013
Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencingQ33285707
Analysis of chromosome breakpoints in neuroblastoma at sub-kilobase resolution using fine-tiling oligonucleotide array CGH.Q34439696
DNA methylation changes in leukaemiaQ34792998
High-throughput screening of chromatin immunoprecipitates using CpG-island microarraysQ35671786
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemiaQ38294261
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)e1882
P577publication date2008-03-26
P1433published inPLOS OneQ564954
P1476titleAn integrative genomic and epigenomic approach for the study of transcriptional regulation
P478volume3

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