scholarly article | Q13442814 |
P50 | author | Tobias Neff | Q41942572 |
P2093 | author name string | S A Armstrong | |
P2860 | cites work | Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains | Q21092474 |
A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells | Q22066257 | ||
Regulation of chromatin structure by site-specific histone H3 methyltransferases | Q24290115 | ||
Somatic mutations in the neurofibromatosis 1 gene in human tumors | Q24293243 | ||
The Polycomb group protein EZH2 directly controls DNA methylation | Q24299020 | ||
Role of histone H2A ubiquitination in Polycomb silencing | Q24305090 | ||
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF | Q24305335 | ||
Role of the polycomb repressive complex 2 in acute promyelocytic leukemia | Q24309258 | ||
Core transcriptional regulatory circuitry in human embryonic stem cells | Q24322016 | ||
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1 | Q24336747 | ||
Global and Hox-specific roles for the MLL1 methyltransferase | Q24529562 | ||
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor | Q40031496 | ||
Protein arginine-methyltransferase-dependent oncogenesis | Q40077054 | ||
The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling | Q40202913 | ||
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. | Q40252270 | ||
Genome-wide profiling of CpG methylation identifies novel targets of aberrant hypermethylation in myeloid leukemia | Q40267029 | ||
The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote | Q40903819 | ||
Di-methyl H4 lysine 20 targets the checkpoint protein Crb2 to sites of DNA damage | Q41915130 | ||
Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment | Q44155422 | ||
Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines | Q44317132 | ||
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation | Q44364520 | ||
5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes | Q45943296 | ||
NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis. | Q46277256 | ||
Spatial distribution of di- and tri-methyl lysine 36 of histone H3 at active genes | Q46370672 | ||
Oncogene-induced senescence as an initial barrier in lymphoma development | Q46634165 | ||
Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells | Q46678698 | ||
Gene expression profiling of pediatric acute myelogenous leukemia | Q47266175 | ||
BMI-1 is highly expressed in M0-subtype acute myeloid leukemia | Q53355262 | ||
Reprogramming the histone code | Q53574922 | ||
Histone deacetylase inhibitors in cancer therapy | Q57272462 | ||
Bmi-1over-expression plays a secondary role in chronic myeloid leukemia transformation | Q63199326 | ||
Hypomethylation of DNA from benign and malignant human colon neoplasms | Q69381419 | ||
Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5 | Q78570048 | ||
Expression of Polycomb-group (PcG) protein BMI-1 predicts prognosis in patients with acute myeloid leukemia | Q80008526 | ||
Chromatin compaction by a polycomb group protein complex | Q81067457 | ||
Bmi-1 is useful as a novel molecular marker for predicting progression of myelodysplastic syndrome and patient prognosis | Q81208548 | ||
Association between BMI-1 expression, acute graft-versus-host disease, and outcome following allogeneic stem cell transplantation from HLA-identical siblings in chronic myeloid leukemia | Q81484529 | ||
The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin | Q81691719 | ||
Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryos | Q82264671 | ||
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3 | Q24531253 | ||
The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4 | Q24536072 | ||
Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. | Q24537640 | ||
Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias | Q24559974 | ||
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin | Q24561636 | ||
DNA methylation profiling of human chromosomes 6, 20 and 22 | Q24607522 | ||
Genome-scale DNA methylation maps of pluripotent and differentiated cells | Q24621431 | ||
ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS | Q24629431 | ||
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells | Q24632506 | ||
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells | Q24655388 | ||
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs | Q24673619 | ||
Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association | Q24675122 | ||
MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein | Q24679773 | ||
Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail | Q27638012 | ||
Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains | Q27641772 | ||
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins | Q27860456 | ||
High-resolution profiling of histone methylations in the human genome | Q27860906 | ||
A bivalent chromatin structure marks key developmental genes in embryonic stem cells | Q27860977 | ||
Chromatin modifications and their function | Q27861067 | ||
COMPASS: a complex of proteins associated with a trithorax-related SET domain protein | Q27931344 | ||
Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association | Q27933908 | ||
hDOT1L links histone methylation to leukemogenesis | Q27935809 | ||
COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression | Q27938795 | ||
Genome-wide location and function of DNA binding proteins | Q28131765 | ||
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality | Q28131773 | ||
Role of histone H3 lysine 27 methylation in Polycomb-group silencing | Q28131795 | ||
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails | Q28216534 | ||
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor | Q28217975 | ||
Control of developmental regulators by Polycomb in human embryonic stem cells | Q28235841 | ||
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3 | Q28242719 | ||
Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug | Q28282479 | ||
The Eukaryotic Genome as an RNA Machine | Q28315740 | ||
Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies | Q36129533 | ||
Assembly of variant histones into chromatin | Q36280301 | ||
Cell cycle-specific reactivation of an inactive X-chromosome locus by 5-azadeoxycytidine | Q36282892 | ||
High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer | Q36423456 | ||
A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification | Q36447915 | ||
Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse | Q36835063 | ||
H3K79 methylation profiles define murine and human MLL-AF4 leukemias | Q36991857 | ||
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia | Q37023597 | ||
Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation | Q37449132 | ||
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia | Q38294261 | ||
Large-scale CpG methylation analysis identifies novel candidate genes and reveals methylation hotspots in acute lymphoblastic leukemia | Q38303652 | ||
The retinoblastoma binding protein RBP2 is an H3K4 demethylase | Q38304373 | ||
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells | Q39840959 | ||
Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia. | Q39975102 | ||
H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment | Q39989822 | ||
Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae | Q28343956 | ||
Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation | Q28505166 | ||
Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex | Q28505248 | ||
NSD1 is essential for early post-implantation development and has a catalytically active SET domain | Q28593118 | ||
Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation | Q28593817 | ||
MLL targets SET domain methyltransferase activity to Hox gene promoters | Q28609771 | ||
PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin | Q28647369 | ||
A chromatin landmark and transcription initiation at most promoters in human cells | Q29547180 | ||
Polycomb complexes repress developmental regulators in murine embryonic stem cells | Q29547274 | ||
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome | Q29547359 | ||
Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation | Q29614333 | ||
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins | Q29614507 | ||
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions | Q29614512 | ||
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly | Q29614718 | ||
Dot1p modulates silencing in yeast by methylation of the nucleosome core | Q29614855 | ||
Histone methyltransferase activity of a Drosophila Polycomb group repressor complex | Q29615394 | ||
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease | Q29617086 | ||
DNA methylation landscapes: provocative insights from epigenomics | Q29617144 | ||
The epigenetic progenitor origin of human cancer | Q29617486 | ||
ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation | Q29618299 | ||
ATP-dependent nucleosome remodeling | Q29618979 | ||
Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression | Q29619380 | ||
Epigenetic stem cell signature in cancer | Q29622897 | ||
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer | Q29622925 | ||
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase | Q33272939 | ||
An integrative genomic and epigenomic approach for the study of transcriptional regulation | Q33325492 | ||
Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase | Q34139275 | ||
Dot1a-AF9 complex mediates histone H3 Lys-79 hypermethylation and repression of ENaCalpha in an aldosterone-sensitive manner | Q34462951 | ||
Evidence for an instructive mechanism of de novo methylation in cancer cells. | Q34489258 | ||
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells | Q34619655 | ||
Trithorax-group protein ASH1 methylates histone H3 lysine 36. | Q34633633 | ||
DNA methylation in health, disease, and cancer | Q34653521 | ||
Epigenetics: a historical overview | Q34713017 | ||
DNA hypomethylation leads to elevated mutation rates | Q34752442 | ||
MicroRNAs in normal and malignant hematopoiesis | Q34785149 | ||
Demethylating agents in myeloid malignancies | Q34847863 | ||
Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay | Q35720707 | ||
Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications | Q35734509 | ||
Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis | Q35901787 | ||
P433 | issue | 7 | |
P921 | main subject | leukemia | Q29496 |
P304 | page(s) | 1243-1251 | |
P577 | publication date | 2009-03-26 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Leukemia | Q6534498 |
P1476 | title | Chromatin maps, histone modifications and leukemia | |
P478 | volume | 23 |
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Q37797467 | DNA Methylation Profiling in Acute Myeloid Leukemia: From Recent Technological Advances to Biological and Clinical Insights |
Q34133706 | DNA methylation of cancer genome. |
Q41861253 | Epigenetic landscape of acute myelogenous leukemia--moving toward personalized medicine |
Q37691486 | Epigenetic mechanisms regulating normal and malignant haematopoiesis: new therapeutic targets for clinical medicine. |
Q37858877 | Gene expression profiling in MDS and AML: potential and future avenues. |
Q37967246 | Genomics of AML: Clinical Applications of Next-Generation Sequencing |
Q47744404 | H3K27 Methylation Dynamics during CD4 T Cell Activation: Regulation of JAK/STAT and IL12RB2 Expression by JMJD3. |
Q34312209 | Leukemia gene atlas--a public platform for integrative exploration of genome-wide molecular data |
Q57272449 | MLL-aberrant leukemia: complete cytogenetic remission following treatment with a histone deacetylase inhibitor (HDACi) |
Q64093595 | Mechanism of Action for HDAC Inhibitors-Insights from Omics Approaches |
Q37962015 | Modulation of gene expression in ovarian cancer by active and repressive histone marks |
Q36443062 | Molecular genetics of AML |
Q82480890 | Myelodysplastic syndromes: lost between two states? |
Q39569092 | NF-Y recruits Ash2L to impart H3K4 trimethylation on CCAAT promoters |
Q38655657 | Nuclear Phosphatidylinositol Signaling: Focus on Phosphatidylinositol Phosphate Kinases and Phospholipases C. |
Q37116118 | Promoter H3K4 methylation dynamically reinforces activation-induced pathways in human CD4 T cells |
Q38023080 | Roles of thioredoxin binding protein (TXNIP) in oxidative stress, apoptosis and cancer |
Q38908846 | Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL. |
Q36430024 | Sequencing histone-modifying enzymes identifies UTX mutations in acute lymphoblastic leukemia |
Q24635185 | Sequencing technologies and genome sequencing |
Q56986793 | Synergistic induction of PI-PLCβ1 signaling by azacitidine and valproic acid in high-risk myelodysplastic syndromes |
Q37226478 | Synthetic genetic targeting of genome instability in cancer. |
Q42909185 | Systematic Identification of Methyllysine-Driven Interactions for Histone and Nonhistone Targets |
Q48223617 | The protective role of DOT1L in UV-induced melanomagenesis |
Q24653972 | Whole-genome cancer analysis as an approach to deeper understanding of tumour biology |