Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc.

scientific article

Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1126/SCIENCE.1154315
P932PMC publication ID2409116
P698PubMed publication ID18420934
P5875ResearchGate publication ID5431645

P50authorJeffrey RavetchQ1359564
Falk NimmerjahnQ1394084
P2093author name stringJames C Paulson
David J Ashline
Robert M Anthony
Vernon N Reinhold
P2860cites workA malaria invasion receptor, the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum recognizes the terminal Neu5Ac(alpha 2-3)Gal- sequences of glycophorin AQ24643787
The antiinflammatory activity of IgG: the intravenous IgG paradoxQ24676548
A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmissionQ28286390
Siglecs and their roles in the immune systemQ28294469
Congruent strategies for carbohydrate sequencing. 1. Mining structural details by MSnQ33224229
Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptorQ33335777
Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune diseaseQ33347581
Intravenous immunoglobulin ameliorates ITP via activating Fc gamma receptors on dendritic cellsQ33371273
FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulinQ33373963
From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulinsQ33860728
Sialic acid-specific lectins: occurrence, specificity and functionQ33994838
Differential expression of five sialyltransferase genes in human tissues.Q34329973
Glycan-based interactions involving vertebrate sialic-acid-recognizing proteinsQ34623034
Influenza virus receptor specificity and cell tropism in mouse and human airway epithelial cellsQ35023814
Characterization of a Plasmodium falciparum erythrocyte-binding protein paralogous to EBA-175Q35869245
Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptorsQ36228422
Restricted reassociation of heavy and light chains from hapten-specific monoclonal antibodiesQ36370217
Immune regulation by the ST6Gal sialyltransferaseQ36475650
The impact of glycosylation on the biological function and structure of human immunoglobulins.Q36618276
Variations in oligosaccharide-protein interactions in immunoglobulin G determine the site-specific glycosylation profiles and modulate the dynamic motion of the Fc oligosaccharidesQ36849871
Glycoengineering of therapeutic glycoproteins: in vitro galactosylation and sialylation of glycoproteins with terminal N-acetylglucosamine and galactose residuesQ38298614
Specificity of S fimbriae on recombinant Escherichia coli: preferential binding to gangliosides expressing NeuGc alpha (2-3)Gal and NeuAc alpha (2-8)NeuAc.Q40267143
Divergent immunoglobulin g subclass activity through selective Fc receptor bindingQ40344836
Carbohydrate structural isomers analyzed by sequential mass spectrometryQ41863702
A comparative study of the N-linked oligosaccharide structures of human IgG subclass proteinsQ42162369
The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectinQ45158584
Large-scale expression of recombinant sialyltransferases and comparison of their kinetic properties with native enzymesQ46155748
In vitro galactosylation of human IgG at 1 kg scale using recombinant galactosyltransferaseQ46723270
Higher levels of sialylated Fc glycans in immunoglobulin G molecules can adversely impact functionality.Q51118036
Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc SialylationQ57253538
α2,3-Sialyltransferase-IV is essential for L-selectin ligand function in inflammationQ57445739
Ultrastructural localization of a macrophage-restricted sialic acid binding hemagglutinin, SER, in macrophage-hematopoietic cell clustersQ68541245
Comparative structural study of the N-linked oligosaccharides of human normal and pathological immunoglobulin GQ68983739
Lectin analysis of human immunoglobulin G N-glycan sialylationQ73334585
P433issue5874
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
P304page(s)373-376
P577publication date2008-04-01
P1433published inScienceQ192864
P1476titleRecapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc.
P478volume320

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Q36768842Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis.
Q36352180Sialylation determines the nephritogenicity of IgG3 cryoglobulins
Q58004245Sialylation levels of anti-proteinase 3 antibodies are associated with the activity of granulomatosis with polyangiitis (Wegener's)
Q36266469Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity
Q57253368Sialylation of anti-histone immunoglobulin G autoantibodies determines their capabilities to participate in the clearance of late apoptotic cells
Q96136750Sialylation of immunoglobulin E is a determinant of allergic pathogenicity
Q33399238Sialylation-independent mechanism involved in the amelioration of murine immune thrombocytopenia using intravenous gammaglobulin.
Q35959088Sialyltransferase and Neuraminidase Levels/Ratios and Sialic Acid Levels in Peripheral Blood B Cells Correlate with Measures of Disease Activity in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Pilot Study
Q58612152Site-selective chemoenzymatic glycoengineering of Fab and Fc glycans of a therapeutic antibody
Q37117619Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
Q53081892Site-specific immobilization of endoglycosidases for streamlined chemoenzymatic glycan remodeling of antibodies.
Q47286747Solid-Phase Enzymatic Remodeling Produces High Yields of Single Glycoform Antibodies
Q38066111Standard and etiology-directed evidence-based therapies in myocarditis: state of the art and future perspectives
Q27684721Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins
Q38615376Structural analysis of Fc/FcγR complexes: a blueprint for antibody design.
Q36624176Structural characterization of GASDALIE Fc bound to the activating Fc receptor FcγRIIIa
Q38257861Structural documentation of glycan epitopes: sequential mass spectrometry and spectral matching
Q42364603Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health
Q50193260Sweet SIGNs: IgG glycosylation leads the way in IVIG-mediated resolution of inflammation
Q38239288Sweet and sour: the role of glycosylation for the anti-inflammatory activity of immunoglobulin G.
Q38851112Sweet but dangerous - the role of immunoglobulin G glycosylation in autoimmunity and inflammation.
Q33414406Sweetened antibodies against humoral autoimmunity: sialylated antibodies are required for IVIg-mediated therapy
Q37123859T cell-independent B cell activation induces immunosuppressive sialylated IgG antibodies.
Q52338988TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation.
Q38207937Targeting B cells and autoantibodies in the therapy of autoimmune diseases
Q52370705Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues.
Q39531026Teaching tolerance: New approaches to enzyme replacement therapy for Pompe disease
Q37206320The Association Between Glycosylation of Immunoglobulin G and Hypertension: A Multiple Ethnic Cross-Sectional Study
Q88669457The Glycoscience of Immunity
Q90460486The Impact of Immunoglobulin G1 Fc Sialylation on Backbone Amide H/D Exchange
Q59360845The Potential Role of Fc-Receptor Functions in the Development of a Universal Influenza Vaccine
Q39088502The Role and Function of Fcγ Receptors on Myeloid Cells
Q35116966The Role of Th17 in Neuroimmune Disorders: A Target for CAM Therapy. Part III
Q47576940The Unexpected Impact of Vaccines on Secondary Bacterial Infections Following Influenza
Q38066414The advantage of specific intravenous immunoglobulin (sIVIG) on regular IVIG: experience of the last decade
Q38117686The carbohydrate switch between pathogenic and immunosuppressive antigen-specific antibodies
Q37638949The challenge and promise of glycomics
Q36213158The criticality of high-resolution N-linked carbohydrate assays and detailed characterization of antibody effector function in the context of biosimilar development
Q38182645The expanding role of therapeutic antibodies
Q35014233The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis
Q90027632The history of IgG glycosylation and where we are now
Q101166851The immune roadmap for understanding multi-system inflammatory syndrome in children: opportunities and challenges
Q42116482The immunoglobulin G1 N-glycan composition affects binding to each low affinity Fc γ receptor
Q36670313The impact of microcarrier culture optimization on the glycosylation profile of a monoclonal antibody
Q37664865The other side of immunoglobulin G: suppressor of inflammation
Q36906422The regulatory power of glycans and their binding partners in immunity
Q37995919The role of sialic acid as a modulator of the anti-inflammatory activity of IgG.
Q24321677The structure of human α-2,6-sialyltransferase reveals the binding mode of complex glycans
Q47410418The sweet spot for biologics: recent advances in characterization of biotherapeutic glycoproteins.
Q54217589Therapeutic Administration of Broadly Neutralizing FI6 Antibody Reveals Lack of Interaction Between Human IgG1 and Pig Fc Receptors.
Q39729881Therapeutic effect of IVIG on inflammatory arthritis in mice is dependent on the Fc portion and independent of sialylation or basophils.
Q37807782Therapeutic use of immunoglobulins
Q34792884To B or not to B: B cells and the Th2-type immune response to helminths
Q47785877Tool for Rapid Analysis of Glycopeptide by Permethylation via One-Pot Site Mapping and Glycan Analysis.
Q42687289Total synthesis of the 2,6-sialylated immunoglobulin G glycopeptide fragment in homogeneous form.
Q36742409Toward a platform for comprehensive glycan sequencing
Q35123102Towards controlling the glycoform: a model framework linking extracellular metabolites to antibody glycosylation
Q26991899Translating basic mechanisms of IgG effector activity into next generation cancer therapies
Q37557375Treatment of chronic inflammatory demyelinating polyneuropathy: from molecular bases to practical considerations.
Q53816522Treatment of inclusion body myositis: is low-dose intravenous immunoglobulin the solution?
Q26822442Treatment of spinal cord injury with intravenous immunoglobulin G: preliminary evidence and future perspectives
Q56924750Treatment options in myocarditis and inflammatory cardiomyopathy : Focus on i. v. immunoglobulins
Q35063963Treatment response in Kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G
Q57640701Treatment with Low Doses of Polyclonal Immunoglobulin Improves B Cell Function During Immune Reconstitution in a Murine Model
Q37456938Tregitope peptides: the active pharmaceutical ingredient of IVIG?
Q26853072Tregitope update: mechanism of action parallels IVIg
Q38125248Trichinella spiralis immunomodulation: an interactive multifactorial process
Q51361920Two N-terminally truncated variants of human β-galactoside α2,6 sialyltransferase I with distinct properties for in vitro protein glycosylation.
Q38232105Type I and type II Fc receptors regulate innate and adaptive immunity
Q42571075Ultrasensitive impedimetric lectin biosensors with efficient antifouling properties applied in glycoprofiling of human serum samples
Q89901292Understanding the role of antibody glycosylation through the lens of severe viral and bacterial diseases
Q36253487Unusual transglycosylation activity of Flavobacterium meningosepticum endoglycosidases enables convergent chemoenzymatic synthesis of core fucosylated complex N-glycopeptides
Q45910300Use of immunoglobulins in the prevention of GvHD in a xenogeneic NOD/SCID/γc- mouse model.
Q91694478Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a recombinant IgG1 Fc hexamer
Q39067348Will sialylation change intravenous immunoglobulin therapy in the future?
Q38055447With or without sugar? (A)glycosylation of therapeutic antibodies
Q85397964[Glycosylation-dependent effector function of IgG antibodies]
Q45964401[Optimizing therapy in patients with severe autoimmune blistering skin diseases].
Q38615353bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression.

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