Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair.

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Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair. is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1000364
P932PMC publication ID2629578
P698PubMed publication ID19197357
P5875ResearchGate publication ID23983698

P50authorHélène GaillardQ57041661
Joaquin ArinoQ60503389
Alfonso Rodríguez-GilQ79458013
Cristina González-AguileraQ81720268
María L García-RubioQ43158419
José L. RevueltaQ36597850
Sebastián ChávezQ37374358
Andrés AguileraQ37382275
P2093author name stringLaia Viladevall
Antonio Marín
Javier Botet
Cristina Tous
Maria José Quintero
P2860cites workCCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylaseQ24292432
Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne SyndromeQ24292732
Cockayne syndrome group B protein enhances elongation by RNA polymerase IIQ24317053
DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex.Q24815044
Genome-wide requirements for resistance to functionally distinct DNA-damaging agentsQ24815105
Roles for Gcn5p and Ada2p in transcription and nucleotide excision repair at the Saccharomyces cerevisiae MET16 geneQ25256763
The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instabilityQ27929526
Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail lengthQ27929903
Evidence that the transcription elongation function of Rpb9 is involved in transcription-coupled DNA repair in Saccharomyces cerevisiaeQ27930103
Bur1 kinase is required for efficient transcription elongation by RNA polymerase II.Q27930313
Molecular evidence for a positive role of Spt4 in transcription elongationQ27930449
The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complexQ27930672
Characterization of the calcium-mediated response to alkaline stress in Saccharomyces cerevisiae.Q27930851
The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylationQ27930884
Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation.Q27930971
Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiaeQ27931688
A new connection of mRNP biogenesis and export with transcription-coupled repairQ27931906
Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II.Q27933085
The Paf1 complex physically and functionally associates with transcription elongation factors in vivoQ27933848
The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1.Q27934025
A Requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3' end formationQ27934649
The Saccharomyces cerevisiae RAD9, RAD17, RAD24 and MEC3 genes are required for tolerating irreparable, ultraviolet-induced DNA damageQ27935475
Histone H2B ubiquitylation is associated with elongating RNA polymerase IIQ27936299
Molecular evidence indicating that the yeast PAF complex is required for transcription elongationQ27936952
RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6.Q27937381
Methylation of histone H3 lysine-79 by Dot1p plays multiple roles in the response to UV damage in Saccharomyces cerevisiae.Q27937420
The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiaeQ27937565
A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damageQ27937572
Regulation of histone modification and cryptic transcription by the Bur1 and Paf1 complexesQ27938071
H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex.Q27939759
The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.Q27939828
The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1pQ27940017
A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signalingQ27940291
Elongation by RNA polymerase II: the short and long of itQ29614529
Histone ubiquitination: triggering gene activityQ29617523
Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivoQ29619233
The SAGA continues: expanding the cellular role of a transcriptional co-activator complexQ30438554
Spt4 modulates Rad26 requirement in transcription-coupled nucleotide excision repairQ30973998
Initiation of DNA repair mediated by a stalled RNA polymerase IIO.Q33231453
Requirement for yeast RAD26, a homolog of the human CSB gene, in elongation by RNA polymerase IIQ33551567
Transcription-coupled DNA repair in yeast transcription factor IIE (TFIIE) mutantsQ33614239
A posttranscriptional role for the yeast Paf1-RNA polymerase II complex is revealed by identification of primary targets.Q53652090
A simple in vivo assay for measuring the efficiency of gene length-dependent processes in yeast mRNA biogenesisQ82401286
The Saccharomyces cerevisiae RAD9 cell cycle checkpoint gene is required for optimal repair of UV-induced pyrimidine dimers in both G(1) and G(2)/M phases of the cell cycleQ39085968
Hpr1 is preferentially required for transcription of either long or G+C-rich DNA sequences in Saccharomyces cerevisiae.Q39528577
Ultraviolet radiation-induced ubiquitination and proteasomal degradation of the large subunit of RNA polymerase II. Implications for transcription-coupled DNA repairQ41056225
A chemical genomic screen in Saccharomyces cerevisiae reveals a role for diphthamidation of translation elongation factor 2 in inhibition of protein synthesis by sordarinQ41876397
CAF1 plays an important role in mRNA deadenylation separate from its contact to CCR4.Q42025763
Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complexQ42747908
Screening the yeast "disruptome" for mutants affecting resistance to the immunosuppressive drug, mycophenolic acidQ43997248
Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolismQ44190695
H2B ubiquitylation plays a role in nucleosome dynamics during transcription elongationQ46493188
Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrestQ46550839
DNA damage-induced Def1-RNA polymerase II interaction and Def1 requirement for polymerase ubiquitylation in vitroQ47422023
Histone acetylation, chromatin remodelling, transcription and nucleotide excision repair in S. cerevisiae: studies with two model genesQ50129981
Gcn5 promotes acetylation, eviction, and methylation of nucleosomes in transcribed coding regions.Q53577981
The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.Q33640104
Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genesQ33695799
E. coli Transcription repair coupling factor (Mfd protein) rescues arrested complexes by promoting forward translocationQ34135671
Rpb4 and Rpb9 mediate subpathways of transcription-coupled DNA repair in Saccharomyces cerevisiaeQ34207143
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
Transcription-coupled repair: a complex affairQ34421058
A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damageQ34430366
The Bur1/Bur2 complex is required for histone H2B monoubiquitination by Rad6/Bre1 and histone methylation by COMPASS.Q34470200
Mechanisms of transcription-coupled DNA repairQ34514438
Terminating the transcript: breaking up is hard to do.Q34520033
Breaking barriers to transcription elongationQ34561019
Ccr4-not complex mRNA deadenylase activity contributes to DNA damage responses in Saccharomyces cerevisiaeQ34570125
The CCR4-NOT complex plays diverse roles in mRNA metabolismQ35185687
The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways?Q35805081
Diverse roles for histone H2A modifications in DNA damage response pathways in yeastQ35844894
Yeast Rpb9 plays an important role in ubiquitylation and degradation of Rpb1 in response to UV-induced DNA damageQ35948156
SAGA unveiled.Q36011032
Bur1/Bur2 and the Ctk complex in yeast: the split personality of mammalian P-TEFbQ36487341
Ccr4 alters cell size in yeast by modulating the timing of CLN1 and CLN2 expressionQ36665844
Contending with transcriptional arrest during RNAPII transcript elongationQ36756252
Mediator complexes and eukaryotic transcription regulation: an overviewQ36942779
Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleusQ37144184
Members of the SAGA and Mediator complexes are partners of the transcription elongation factor TFIIS.Q37592638
Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regionsQ38314041
Defective Kin28, a subunit of yeast TFIIH, impairs transcription-coupled but not global genome nucleotide excision repair.Q38329870
The structure and function of RAD6 and RAD18 DNA repair genes of Saccharomyces cerevisiaeQ38778956
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P304page(s)e1000364
P577publication date2009-02-06
P1433published inPLOS GeneticsQ1893441
P1476titleGenome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair
P478volume5

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cites work (P2860)
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