Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodies

scientific article

Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodies is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/GKP1145
P932PMC publication ID2836572
P698PubMed publication ID20007602
P5875ResearchGate publication ID40685359

P50authorYong-Sung KimQ40568330
P2093author name stringJeong-Sun Kim
Ji-Young Jang
Myung-Hee Kwon
Woo-Ram Lee
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Polyreactive anti-DNA monoclonal antibodies and a derived peptide as vectors for the intracytoplasmic and intranuclear translocation of macromoleculesQ28379506
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Illuminating the silence: understanding the structure and function of small RNAsQ29622905
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Picomolar affinity fibronectin domains engineered utilizing loop length diversity, recursive mutagenesis, and loop shufflingQ33349284
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Fusion with an RNA binding domain to confer target RNA specificity to an RNase: design and engineering of Tat-RNase H that specifically recognizes and cleaves HIV-1 RNA in vitroQ34595695
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Sequence-specific binding of single-stranded RNA: is there a code for recognition?Q35128019
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Approaches for the sequence-specific knockdown of mRNA.Q35597089
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Destroying RNA as a therapeutic approachQ36447193
Creating a ribonuclease T-tat that preferentially recognizes and hydrolyzes HIV-1 TAR RNA in vitro and in vivoQ36457182
Enhancing and confirming the specificity of RNAi experimentsQ36575386
Generation of sequence-specific, high affinity anti-DNA antibodies.Q38302516
A novel agonistic antibody to human death receptor 4 induces apoptotic cell death in various tumor cells without cytotoxicity in hepatocytesQ39819752
Recombinant immunoproapoptotic proteins with furin site can translocate and kill HER2-positive cancer cellsQ40033581
Nuclear localizing anti-DNA antibodies enter cells via caveoli and modulate expression of caveolin and p53.Q40435519
Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells.Q40456753
Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines.Q40616262
Effects of solutes on solubilization and refolding of proteins from inclusion bodies with high hydrostatic pressureQ41961798
Structural modeling of sequence specificity by an autoantibody against single-stranded DNA.Q42798676
Generation of humanized anti-DNA hydrolyzing catalytic antibodies by complementarity determining region graftingQ46298474
A nucleic acid-hydrolyzing antibody penetrates into cells via caveolae-mediated endocytosis, localizes in the cytosol and exhibits cytotoxicityQ47994013
A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells.Q53565727
A Comprehensive Model for the Cellular Uptake of Cationic Cell-penetrating PeptidesQ57374314
Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificityQ64388542
Mechanisms of cellular penetration and nuclear localization of an anti-double strand DNA autoantibodyQ64389359
Ribonuclease inhibitor from human placenta. Purification and propertiesQ67012561
DNA and heparin alter the internalization process of anti-DNA monoclonal antibodies according to patterns typical of both the charged molecule and the antibodyQ74136670
Anti-DNA autoantibodies reveal toxicity to tumor cell linesQ77209155
Making cell-permeable antibodies (Transbody) through fusion of protein transduction domains (PTD) with single chain variable fragment (scFv) antibodies: potential advantages over antibodies expressed within the intracellular environment (Intrabody)Q81638299
Cell-penetrating anti-native DNA antibodies trigger apoptosis through both the neglect and programmed pathwaysQ82038431
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectgene silencingQ1431332
antibodyQ79460
P304page(s)1596-1609
P577publication date2009-12-09
P1433published inNucleic Acids ResearchQ135122
P1476titleGene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodies
P478volume38

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cites work (P2860)
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Q50743140Variable Heavy Chain Domain Derived from a Cell-Penetrating Anti-DNA Monoclonal Antibody for the Intracellular Delivery of Biomolecules.

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