| scholarly article | Q13442814 |
| P2093 | author name string | Atul Kapila | |
| K Dane Wittrup | |||
| Benjamin J Hackel | |||
| P2860 | cites work | The three-dimensional structure of the tenth type III module of fibronectin: an insight into RGD-mediated interactions | Q24294355 |
| In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity | Q24563455 | ||
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| Antigen selection from an HIV-1 immune antibody library displayed on yeast yields many novel antibodies compared to selection from the same library displayed on phage. | Q33269999 | ||
| Evolution of an interloop disulfide bond in high-affinity antibody mimics based on fibronectin type III domain and selected by yeast surface display: molecular convergence with single-domain camelid and shark antibodies | Q33279876 | ||
| Isolating and engineering human antibodies using yeast surface display | Q33280948 | ||
| An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues | Q36791806 | ||
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| CDR3 length in antigen-specific immune receptors | Q41875752 | ||
| Exploring the potential of the monobody scaffold: effects of loop elongation on the stability of a fibronectin type III domain | Q44324864 | ||
| Protein folding stability can determine the efficiency of escape from endoplasmic reticulum quality control | Q47792459 | ||
| Modeling DNA mutation and recombination for directed evolution experiments | Q56901668 | ||
| Fine affinity discrimination by yeast surface display and flow cytometry | Q56901936 | ||
| Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency | Q56902099 | ||
| Rapid method for measuring ScFv thermal stability by yeast surface display | Q73215314 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1238-1252 | |
| P577 | publication date | 2008-06-24 | |
| P1433 | published in | Journal of Molecular Biology | Q925779 |
| P1476 | title | Picomolar affinity fibronectin domains engineered utilizing loop length diversity, recursive mutagenesis, and loop shuffling | |
| P478 | volume | 381 |
| Q35954982 | A 45-Amino-Acid Scaffold Mined from the PDB for High-Affinity Ligand Engineering |
| Q27667402 | A De Novo Protein Binding Pair By Computational Design and Directed Evolution |
| Q36293727 | A Gradient of Sitewise Diversity Promotes Evolutionary Fitness for Binder Discovery in a Three-Helix Bundle Protein Scaffold. |
| Q58101920 | A Novel Engineered Small Protein for Positron Emission Tomography Imaging of Human Programmed Death Ligand-1 : Validation in Mouse Models and Human Cancer Tissues |
| Q28072407 | A current perspective on applications of macrocyclic-peptide-based high-affinity ligands |
| Q27660385 | A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain |
| Q35762691 | A switchable yeast display/secretion system |
| Q33743756 | Adnectins: engineered target-binding protein therapeutics |
| Q38726211 | Affinity Maturation of a Cyclic Peptide Handle for Therapeutic Antibodies Using Deep Mutational Scanning |
| Q36254467 | An enhanced approach for engineering thermally stable proteins using yeast display |
| Q36926959 | Antibody-mediated neutralization of perfringolysin o for intracellular protein delivery |
| Q26823830 | Applications of Yeast Surface Display for Protein Engineering |
| Q47831558 | Arginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs. |
| Q88500183 | Artificial Anti-Tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to Each of the Murine FcγR Types |
| Q28083126 | Artificial affinity proteins as ligands of immunoglobulins |
| Q33970172 | Bacterial display in combinatorial protein engineering. |
| Q52372665 | Beyond antibody engineering: directed evolution of alternative binding scaffolds and enzymes using yeast surface display. |
| Q38364462 | Beyond peptides and mAbs--current status and future perspectives for biotherapeutics with novel constructs |
| Q36595042 | Binding efficiency of protein-protein complexes |
| Q31082210 | Bispecific engineered antibody domains (nanoantibodies) that interact noncompetitively with an HIV-1 neutralizing epitope and FcRn |
| Q37998496 | Candidate antibody-based therapeutics against HIV-1. |
| Q26849777 | Cells and cell lysates: a direct approach for engineering antibodies against membrane proteins using yeast surface display |
| Q41481730 | Characterization of monobody scaffold interactions with ligand via force spectroscopy and steered molecular dynamics. |
| Q37367962 | Circumventing the stability-function trade-off in an engineered FN3 domain |
| Q27678929 | Computational Design of a Protein-Based Enzyme Inhibitor |
| Q35624791 | Computational design of protein antigens that interact with the CDR H3 loop of HIV broadly neutralizing antibody 2F5. |
| Q88812075 | Constrained Combinatorial Libraries of Gp2 Proteins Enhance Discovery of PD-L1 Binders |
| Q34575951 | Convergent potency of internalized gelonin immunotoxins across varied cell lines, antigens, and targeting moieties |
| Q34535080 | Design Principles for SuCESsFul Biosensors: Specific Fluorophore/Analyte Binding and Minimization of Fluorophore/Scaffold Interactions |
| Q36254454 | Designed hydrophilic and charge mutations of the fibronectin domain: towards tailored protein biodistribution |
| Q90113232 | Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain |
| Q37274437 | Development of GFP-based biosensors possessing the binding properties of antibodies |
| Q36296227 | Directed Evolution of Protein Thermal Stability Using Yeast Surface Display. |
| Q30009044 | Directed Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase |
| Q35092308 | Directed evolution of a yeast-displayed HIV-1 SOSIP gp140 spike protein toward improved expression and affinity for conformational antibodies |
| Q38857819 | Directed evolution of anti-HER2 DARPins by SNAP display reveals stability/function trade-offs in the selection process |
| Q37724050 | Efficient affinity maturation of antibody variable domains requires co-selection of compensatory mutations to maintain thermodynamic stability |
| Q34289289 | Engineered Fc based antibody domains and fragments as novel scaffolds |
| Q26766715 | Engineered IgG1-Fc--one fragment to bind them all |
| Q35044156 | Engineered antibody variable and constant domains as therapeutic candidates |
| Q33447473 | Engineered cystine knot peptides that bind alphavbeta3, alphavbeta5, and alpha5beta1 integrins with low-nanomolar affinity |
| Q33661948 | Engineering an antibody with picomolar affinity to DOTA chelates of multiple radionuclides for pretargeted radioimmunotherapy and imaging |
| Q90707091 | Engineering of a novel subnanomolar affinity fibronectin III domain binder targeting human programmed death-ligand 1 |
| Q34097126 | Epidermal growth factor receptor downregulation by small heterodimeric binding proteins |
| Q34317754 | Expression, purification, and characterization of engineered antibody CH2 and VH domains. |
| Q64882409 | Fab is the most efficient format to express functional antibodies by yeast surface display. |
| Q42090622 | Fast photochemical oxidation of proteins (FPOP) maps the epitope of EGFR binding to adnectin |
| Q55257427 | Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding. |
| Q34273084 | Foundations for the design and implementation of synthetic genetic circuits |
| Q33518250 | Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodies |
| Q38773272 | Geometry and expression enhance enrichment of functional yeast-displayed ligands via cell panning |
| Q35780298 | High-Throughput Ligand Discovery Reveals a Sitewise Gradient of Diversity in Broadly Evolved Hydrophilic Fibronectin Domains |
| Q33429603 | Highly avid magnetic bead capture: an efficient selection method for de novo protein engineering utilizing yeast surface display |
| Q33959016 | Human monoclonal antibody fragments binding to insulin-like growth factors I and II with picomolar affinity |
| Q39167522 | In vitro-engineered non-antibody protein therapeutics |
| Q35692461 | Isolation and Characterization of a Monobody with a Fibronectin Domain III Scaffold That Specifically Binds EphA2. |
| Q30010192 | Isolation of monobodies that bind specifically to the SH3 domain of the Fyn tyrosine protein kinase |
| Q26827731 | Microbial enzymes: tools for biotechnological processes |
| Q27670485 | Molecular Basis of a Million-Fold Affinity Maturation Process in a Protein–Protein Interaction |
| Q90130270 | Monobodies as enabling tools for structural and mechanistic biology |
| Q35881238 | N-terminal residues of an HIV-1 gp41 membrane-proximal external region antigen influence broadly neutralizing 2F5-like antibodies |
| Q37227583 | N-terminal truncation of an isolated human IgG1 CH2 domain significantly increases its stability and aggregation resistance |
| Q35553193 | Nanoparticle PEGylation for imaging and therapy |
| Q33732694 | NextGen protein design |
| Q99560991 | Noncompetitive allosteric antagonism of death receptor 5 by a synthetic affibody ligand |
| Q34340960 | Optimization of ordered plasmid assembly by gap repair in Saccharomyces cerevisiae |
| Q33714885 | PCRless library mutagenesis via oligonucleotide recombination in yeast |
| Q34471346 | Peptide aptamers: development and applications |
| Q34215858 | Protein selection using yeast surface display |
| Q33920753 | ScaffoldSeq: Software for characterization of directed evolution populations |
| Q35160784 | Selection of high-affinity Centyrin FN3 domains from a simple library diversified at a combination of strand and loop positions |
| Q33931475 | Shortened engineered human antibody CH2 domains: increased stability and binding to the human neonatal Fc receptor |
| Q33602122 | Stability and CDR composition biases enrich binder functionality landscapes |
| Q34348335 | Strategies to control the binding mode of de novo designed protein interactions |
| Q35799445 | Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step |
| Q64968393 | Synthetic 10FN3-based mono- and bivalent inhibitors of MDM2/X function. |
| Q27676439 | Teaching an Old Scaffold New Tricks: Monobodies Constructed Using Alternative Surfaces of the FN3 Scaffold |
| Q33523422 | The full amino acid repertoire is superior to serine/tyrosine for selection of high affinity immunoglobulin G binders from the fibronectin scaffold |
| Q34474034 | The influence of adnectin binding on the extracellular domain of epidermal growth factor receptor |
| Q36316025 | Titratable Avidity Reduction Enhances Affinity Discrimination in Mammalian Cellular Selections of Yeast-Displayed Ligands |
| Q61814870 | Toxin Neutralization Using Alternative Binding Proteins |
| Q30375870 | Ultrasound Molecular Imaging of the Breast Cancer Neovasculature using Engineered Fibronectin Scaffold Ligands: A Novel Class of Targeted Contrast Ultrasound Agent |
| Q92235384 | Validation and Stabilization of a Prophage Lysin of Clostridium perfringens by Using Yeast Surface Display and Coevolutionary Models |
| Q34317747 | Yeast display of engineered antibody domains |
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