Variable Heavy Chain Domain Derived from a Cell-Penetrating Anti-DNA Monoclonal Antibody for the Intracellular Delivery of Biomolecules.

scientific article published on 7 April 2017

Variable Heavy Chain Domain Derived from a Cell-Penetrating Anti-DNA Monoclonal Antibody for the Intracellular Delivery of Biomolecules. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/08820139.2017.1301466
P698PubMed publication ID28388234

P2093author name stringPavithra Pravinsagar
Sae-Ran Im
Sun-Woo Im
Young-Ju Jang
P2860cites workMouse monoclonal autoantibodies penetrate mouse macrophage cells and stimulate NF-kappaB activation and TNF-alpha releaseQ47941544
A nucleic acid-hydrolyzing antibody penetrates into cells via caveolae-mediated endocytosis, localizes in the cytosol and exhibits cytotoxicityQ47994013
Suppression of MMP-9 expression in brain microvascular endothelial cells (BMVEC) using a gold nanorod (GNR)-siRNA nanoplexQ48935336
Cell-penetrating autoantibody induces caspase-mediated apoptosis through catalytic hydrolysis of DNA.Q53576539
The structural basis for DNA binding by an anti-DNA autoantibodyQ56978425
Spontaneously produced anti-DNA/DNase I autoantibodies modulate nuclear apoptosis in living cellsQ58960467
Antibody to nuclear ribonucleoprotein penetrates live human mononuclear cells through Fc receptorsQ59060502
Lupus nephritis: the central role of nucleosomes revealedQ24649566
Drug delivery and nanoparticles:applications and hazardsQ24655744
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Characterization of the histone H1-binding protein, NASP, as a cell cycle-regulated somatic proteinQ28140714
Polyreactive anti-DNA monoclonal antibodies and a derived peptide as vectors for the intracytoplasmic and intranuclear translocation of macromoleculesQ28379506
Cellular internalization mechanism and intracellular trafficking of filamentous M13 phages displaying a cell-penetrating transbody and TAT peptideQ28484366
A novel cell-penetrating peptide derived from human eosinophil cationic proteinQ28487590
Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodiesQ33518250
RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivoQ34379366
Cell penetrable humanized-VH/V(H)H that inhibit RNA dependent RNA polymerase (NS5B) of HCV.Q34474314
Anti-DNA antibodies in the pathogenesis of lupus nephritis--the emerging mechanismsQ34754486
Depletion of the histone chaperone tNASP inhibits proliferation and induces apoptosis in prostate cancer PC-3 cellsQ34999851
Generation and Characterization of Human Single-Chain Antibodies Against Polycyclic Aromatic Hydrocarbons.Q35710876
Assembly and function of RNA silencing complexesQ36011649
TransMabs: cell-penetrating antibodies, the next generationQ36065969
Search for inhibitors of endocytosis: Intended specificity and unintended consequencesQ36714567
Cell penetrating peptides: intracellular pathways and pharmaceutical perspectivesQ36795351
Drug delivery of siRNA therapeutics: potentials and limits of nanosystems.Q37221348
Antibody fragments: hope and hypeQ37679663
Targeting antibodies to the cytoplasmQ37811739
Nanobody; an old concept and new vehicle for immunotargetingQ37829737
Enhancement of oxidative cleavage of DNA by the binding sites of two anti-double-stranded DNA antibodiesQ38360367
Heavy chain dominance in the binding of DNA by a lupus mouse monoclonal autoantibodyQ38362185
Cell- and nuclear-penetrating anti-dsDNA autoantibodies have multiple arginines in CDR3 of VH and increase cellular level of pERK and Bcl-2 in mesangial cellsQ38851547
Downregulation of tNASP inhibits proliferation through regulating cell cycle-related proteins and inactive ERK/MAPK signal pathway in renal cell carcinoma cellsQ38911026
siRNA nanoparticles: the future of RNAi therapeutics for oncology?Q38938368
A cell-penetrating bispecific antibody for therapeutic regulation of intracellular targets.Q39302577
Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imagingQ39325717
A single-chain fragment against prostate specific membrane antigen as a tool to build theranostic reagents for prostate cancer.Q44430715
Stable suppression of tumorigenicity by virus-mediated RNA interferenceQ45730805
Effect of human anti-DNA antibodies on proximal renal tubular epithelial cell cytokine expression: implications on tubulointerstitial inflammation in lupus nephritis.Q46726702
P433issue5
P304page(s)500-517
P577publication date2017-04-07
P1433published inImmunological InvestigationsQ15754982
P1476titleVariable Heavy Chain Domain Derived from a Cell-Penetrating Anti-DNA Monoclonal Antibody for the Intracellular Delivery of Biomolecules.
P478volume46