Cell penetrable humanized-VH/V(H)H that inhibit RNA dependent RNA polymerase (NS5B) of HCV.

scientific article

Cell penetrable humanized-VH/V(H)H that inhibit RNA dependent RNA polymerase (NS5B) of HCV. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...749254T
P356DOI10.1371/JOURNAL.PONE.0049254
P932PMC publication ID3493538
P698PubMed publication ID23145135
P5875ResearchGate publication ID233397264

P50authorKiattawee ChoowongkomonQ56881876
Wanpen ChaicumpaQ60976993
P2093author name stringPotjanee Srimanote
Jeeraphong Thanongsaksrikul
Santi Maneewatch
Kunan Bangphoomi
Kanyarat Thueng-in
Ornnuthchar Poungpair
P2860cites workProspects for personalizing antiviral therapy for hepatitis C virus with pharmacogeneticsQ42731526
Detection of hepatitis C virus (HCV) RNA in the liver of healthy, anti-HCV antibody-positive, serum HCV RNA-negative patients with normal alanine aminotransferase levelsQ43000433
A nonisotopic assay method for hepatitis C virus NS5B polymeraseQ43036582
Modulation of hepatitis C virus RNA-dependent RNA polymerase activity by structure-based site-directed mutagenesisQ44081160
'Camelising' human antibody fragments: NMR studies on VH domains.Q54639929
Covalent immobilization of DNA onto polystyrene microwells: The molecules are only bound at the 5′ endQ67855297
Proteome and immunome of the venom of the Thai cobra, Naja kaouthiaQ80016957
Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerasesQ21256431
Properties, production, and applications of camelid single-domain antibody fragmentsQ24676749
PROCHECK: a program to check the stereochemical quality of protein structuresQ26778411
De novo initiation of RNA synthesis by hepatitis C virus nonstructural protein 5B polymeraseQ27469633
Template requirements for RNA synthesis by a recombinant hepatitis C virus RNA-dependent RNA polymeraseQ27469758
Robust hepatitis C virus infection in vitroQ27470013
Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activityQ27480890
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virusQ27486092
Development of Intergenotypic Chimeric Replicons To Determine the Broad-Spectrum Antiviral Activities of Hepatitis C Virus Polymerase InhibitorsQ27487022
Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active siteQ27619818
Production of infectious hepatitis C virus in tissue culture from a cloned viral genomeQ27860899
Naturally occurring antibodies devoid of light chainsQ28269589
Human monoclonal ScFv neutralize lethal Thai cobra, Naja kaouthia, neurotoxinQ33402028
A V H H that neutralizes the zinc metalloproteinase activity of botulinum neurotoxin type AQ33525766
Interactions of protein antigens with antibodiesQ33594252
Antiviral stilbene 1,2-diamines prevent initiation of hepatitis C virus RNA replication at the outset of infectionQ33853582
Botulinum neurotoxins and botulism: a novel therapeutic approachQ34070659
Humanized-single domain antibodies (VH/VHH) that bound specifically to Naja kaouthia phospholipase A2 and neutralized the enzymatic activityQ34360982
Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitorsQ34399887
Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chainsQ34662422
Optimal therapy of hepatitis C.Q34984079
Characterization of resistance to the nonnucleoside NS5B inhibitor filibuvir in hepatitis C virus-infected patientsQ35806182
Nomenclature and functions of RNA-directed RNA polymerasesQ36394550
The essential role of C-terminal residues in regulating the activity of hepatitis C virus RNA-dependent RNA polymerase.Q38361069
A human single chain transbody specific to matrix protein (M1) interferes with the replication of influenza A virusQ39691105
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)e49254
P577publication date2012-11-08
P1433published inPLOS OneQ564954
P1476titleCell penetrable humanized-VH/V(H)H that inhibit RNA dependent RNA polymerase (NS5B) of HCV.
P478volume7

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