| scholarly article | Q13442814 |
| P50 | author | Fabrice Chimienti | Q57023843 |
| Frans Schuit | Q37064484 | ||
| P2093 | author name string | Katleen Lemaire | |
| P2860 | cites work | Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells | Q24292494 |
| Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules | Q24301974 | ||
| In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion | Q24303979 | ||
| The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes | Q24675521 | ||
| Structure of the zinc transporter YiiP | Q27647503 | ||
| Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression | Q27865298 | ||
| The SLC39 family of metal ion transporters | Q28204280 | ||
| Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants | Q28249275 | ||
| A genome-wide association study identifies novel risk loci for type 2 diabetes | Q28287727 | ||
| Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands | Q28507906 | ||
| Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis? | Q28566179 | ||
| The role of assembly in insulin's biosynthesis | Q28609745 | ||
| A variant in CDKAL1 influences insulin response and risk of type 2 diabetes | Q29614878 | ||
| Maternal and child undernutrition: global and regional exposures and health consequences | Q29615511 | ||
| Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function | Q30500111 | ||
| Use of national food balance data to estimate the adequacy of zinc in national food supplies: methodology and regional estimates | Q31016589 | ||
| Zinc as a paracrine effector in pancreatic islet cell death | Q31399262 | ||
| Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function | Q33296991 | ||
| The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies | Q33337217 | ||
| SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress. | Q33459222 | ||
| A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway | Q33677437 | ||
| Gene duplication and the uniqueness of vertebrate genomes circa 1970-1999. | Q33794254 | ||
| Zinc in relation to diabetes and oxidative disease | Q33913098 | ||
| miR-183-96-182 cluster is overexpressed in prostate tissue and regulates zinc homeostasis in prostate cells | Q34064071 | ||
| Role of zinc in insulin biosynthesis. Some possible zinc-insulin interactions in the pancreatic B-cell | Q34275166 | ||
| The pH of the secretory pathway: measurement, determinants, and regulation | Q34340217 | ||
| Zinc-ligand interactions modulate assembly and stability of the insulin hexamer -- a review | Q34450433 | ||
| Zinc requirements and the risks and benefits of zinc supplementation | Q34516608 | ||
| Insulin within islets is a physiologic glucagon release inhibitor | Q34623723 | ||
| Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis | Q34631381 | ||
| Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function | Q34680127 | ||
| The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study | Q46715719 | ||
| Familial hyperproinsulinemia due to a proposed defect in conversion of proinsulin to insulin. | Q51641281 | ||
| Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion. | Q53499112 | ||
| Amino Acid Sequences of Insulins | Q54038397 | ||
| Structural lability of zinc-containing secretion granules of pancreatic ?-cells after exposure to hydrogen sulphide | Q54080697 | ||
| Hyperzincuria in insulin treated diabetes mellitus—its relation to glucose homeostasis and insulin administration | Q58170028 | ||
| Abnormal development of preimplantation rat eggs after three days of maternal dietary zinc deficiency | Q59077377 | ||
| +647 A/C and +1245 MT1A polymorphisms in the susceptibility of diabetes mellitus and cardiovascular complications | Q60691156 | ||
| Interplay of nutrients and hormones in the regulation of glucagon release | Q69866355 | ||
| Hyperzincuria in individuals with insulin-dependent diabetes mellitus: concurrent zinc status and the effect of high-dose zinc supplementation | Q72883113 | ||
| Identification and purification of functional human beta-cells by a new specific zinc-fluorescent probe | Q73644478 | ||
| Zinc effects on hyperglycemia and hypoleptinemia in streptozotocin-induced diabetic mice | Q73727072 | ||
| Interaction between insulin and zinc in the islets of Langerhans | Q74561931 | ||
| Zinc, not insulin, regulates the rat alpha-cell response to hypoglycemia in vivo | Q79818781 | ||
| No REST for healthy beta cells | Q81312924 | ||
| Downregulation of ZnT8 expression in pancreatic β-cells of diabetic mice | Q82566962 | ||
| Crystalline insulin | Q83904163 | ||
| Effect of zinc on early graft failure following intraportal islet transplantation in rat recipients | Q85017048 | ||
| [Some aspects of zinc metabolism in diabetics] | Q93794585 | ||
| Glucose regulates free cytosolic Zn²⁺ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cells | Q35110905 | ||
| Noninvasive MRI of β-cell function using a Zn2+-responsive contrast agent. | Q35546868 | ||
| Apoptosis in the normal and inflamed airway epithelium: role of zinc in epithelial protection and procaspase-3 regulation | Q35557620 | ||
| Plasticity of the beta cell insulin secretory competence: preparing the pancreatic beta cell for the next meal | Q35794504 | ||
| Regulation of zinc-responsive Slc39a5 (Zip5) translation is mediated by conserved elements in the 3'-untranslated region | Q35823533 | ||
| The neurobiology of zinc in health and disease | Q36126098 | ||
| Mechanism and regulation of cellular zinc transport | Q36876009 | ||
| A common nonsynonymous single nucleotide polymorphism in the SLC30A8 gene determines ZnT8 autoantibody specificity in type 1 diabetes | Q36906356 | ||
| Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice. | Q37329685 | ||
| An update on mutations of the SLC39A4 gene in acrodermatitis enteropathica | Q37445718 | ||
| Mammalian zinc transporters: nutritional and physiologic regulation | Q37463198 | ||
| A Bovine Pancreatic Enzyme Catalyzing the Conversion of Proinsulin to Insulin | Q37478677 | ||
| Zinc and diabetes--clinical links and molecular mechanisms | Q37482583 | ||
| Role of oxidative stress in development of complications in diabetes | Q37681089 | ||
| Zinc and redox signaling: perturbations associated with cardiovascular disease and diabetes mellitus | Q37766871 | ||
| Zinc restriction during different periods of life: influence in renal and cardiovascular diseases | Q37809284 | ||
| The "magic numbers" of metallothionein | Q37853420 | ||
| A role for zinc in pancreatic islet β-cell cross-talk with the α-cell during hypoglycaemia | Q37913519 | ||
| Regulation of glucagon secretion by zinc: lessons from the β cell-specific Znt8 knockout mouse model. | Q37913522 | ||
| Species variation in the amino acid sequence of insulin | Q38707401 | ||
| Potential antioxidant effects of zinc and chromium supplementation in people with type 2 diabetes mellitus | Q38874725 | ||
| Demonstration and characterization of the heterodimerization of ZnT5 and ZnT6 in the early secretory pathway. | Q39798819 | ||
| Glucagon physiology and pathophysiology in the light of new advances | Q39832294 | ||
| Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic alpha-cells. | Q40416559 | ||
| Recombinant-DNA-derived insulin analogues as potentially useful therapeutic agents | Q40533579 | ||
| Zinc and manganese contents of micro-dissected pancreatic islets of some rodents. A microchemical study in adult and newborn guinea pigs, rats, Chinese hamsters and spiny mice | Q40824779 | ||
| Expression of neuronal traits in pancreatic beta cells. Implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer. | Q41133907 | ||
| Video image analysis of labile zinc in viable pancreatic islet cells using a specific fluorescent probe for zinc | Q41457439 | ||
| Molecular and cellular regulation of prohormone processing | Q41757608 | ||
| Differences in the nature of the interaction of insulin and proinsulin with zinc | Q41867469 | ||
| Intracellular transport of proinsulin in pancreatic beta-cells. Structural maturation probed by disulfide accessibility | Q41932562 | ||
| The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer | Q41961853 | ||
| Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells | Q42459267 | ||
| Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets | Q42466949 | ||
| Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic beta-cells by promoting insulin gene transcription | Q42473751 | ||
| Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion. | Q43083300 | ||
| Cognitive loss in zinc transporter-3 knock-out mice: a phenocopy for the synaptic and memory deficits of Alzheimer's disease? | Q43174632 | ||
| Insulin aggregation in aqueous media and its effect on alpha-chymotrypsin-mediated proteolytic degradation | Q43610509 | ||
| Dietary zinc supplementation attenuates hyperglycemia in db/db mice | Q43614128 | ||
| Role of cellular zinc in programmed cell death: temporal relationship between zinc depletion, activation of caspases, and cleavage of Sp family transcription factors. | Q43620589 | ||
| Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells. | Q44364388 | ||
| Guinea pig insulin. I. Purification and physical properties | Q46263712 | ||
| Kiss-and-run exocytosis and fusion pores of secretory vesicles in human beta-cells. | Q46364689 | ||
| P433 | issue | 3 | |
| P304 | page(s) | 202-211 | |
| P577 | publication date | 2012-06-01 | |
| P1433 | published in | Journal of Diabetes Investigation | Q28207066 |
| P1476 | title | Zinc transporters and their role in the pancreatic β-cell | |
| P478 | volume | 3 |
| Q49566480 | A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells |
| Q89550590 | C-Terminal Domain of the Human Zinc Transporter hZnT8 Is Structurally Indistinguishable from Its Disease Risk Variant (R325W) |
| Q42504848 | Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells |
| Q36427543 | Disease, Models, Variants and Altered Pathways-Journeying RGD Through the Magnifying Glass |
| Q90574039 | Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress |
| Q33671124 | Exploring the Association Between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and Nickel |
| Q64101205 | Genetic, Functional, and Immunological Study of ZnT8 in Diabetes |
| Q89882659 | Insights into pancreatic islet cell dysfunction from type 2 diabetes mellitus genetics |
| Q38817211 | Islet Autoantibodies |
| Q35854587 | Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging |
| Q47710542 | SLC30A family expression in the pancreatic islets of humans and mice: cellular localization in the β-cells. |
| Q27704194 | Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin |
| Q30547080 | The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance |
| Q41689708 | The dynamic plasticity of insulin production in β-cells. |
| Q27333587 | The physiological effects of deleting the mouse SLC30A8 gene encoding zinc transporter-8 are influenced by gender and genetic background |
| Q48284705 | Ultrastructure of endocrine pancreatic granules during pancreatic differentiation in the grass snake, Natrix natrix L. (Lepidosauria, Serpentes). |
| Q37673300 | Zinc Status Biomarkers and Cardiometabolic Risk Factors in Metabolic Syndrome: A Case Control Study |
| Q55435824 | Zinc Transport Gets Its Zing Back: Double-Knockout of ZnT7 and ZnT8 Reveals the Importance of Zinc Transporters to Insulin Secretion. |
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