| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2014PLoSO...991613A |
| P356 | DOI | 10.1371/JOURNAL.PONE.0091613 |
| P932 | PMC publication ID | 4023934 |
| P698 | PubMed publication ID | 24838000 |
| P5875 | ResearchGate publication ID | 262418900 |
| P50 | author | Elisabetta Ciani | Q56550093 |
| Dominika Farley | Q57442510 | ||
| Enrico Castroflorio | Q57442523 | ||
| Alexei L. Vyssotski | Q37380988 | ||
| Yang Zhan | Q41655030 | ||
| Maurizio Giustetto | Q42175978 | ||
| Tommaso Pizzorusso | Q42175985 | ||
| P2093 | author name string | Camilla Mattucci | |
| Cornelius T Gross | |||
| Claudia Fuchs | |||
| Davide Silingardi | |||
| Elena Amendola | |||
| Eleonora Calcagno | |||
| Giuseppina Lonetti | |||
| P2860 | cites work | CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome | Q24303656 |
| S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway | Q24603083 | ||
| CDKL5 expression is modulated during neuronal development and its subcellular distribution is tightly regulated by the C-terminal tail | Q24651382 | ||
| A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development | Q24798758 | ||
| Neurotrophin signal transduction in the nervous system | Q27876223 | ||
| Novel mutations in the CDKL5 gene, predicted effects and associated phenotypes | Q28236247 | ||
| The story of Rett syndrome: from clinic to neurobiology | Q28256549 | ||
| CDKL5 influences RNA splicing activity by its association to the nuclear speckle molecular machinery | Q28257945 | ||
| Seizures and electroencephalographic findings in CDKL5 mutations: case report and review | Q28269052 | ||
| The CDKL5 disorder is an independent clinical entity associated with early-onset encephalopathy | Q28272644 | ||
| Key clinical features to identify girls with CDKL5 mutations | Q28293847 | ||
| A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome | Q28504458 | ||
| CDKL5, a protein associated with rett syndrome, regulates neuronal morphogenesis via Rac1 signaling | Q28574630 | ||
| Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice | Q28595061 | ||
| Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP | Q29547505 | ||
| Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation | Q29616327 | ||
| Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice | Q29616328 | ||
| MeCP2 mutation results in compartment-specific reductions in dendritic branching and spine density in layer 5 motor cortical neurons of YFP-H mice | Q34193020 | ||
| Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model. | Q51820369 | ||
| CDKL5/Stk9 kinase inactivation is associated with neuronal developmental disorders. | Q51923623 | ||
| Early onset seizures and Rett-like features associated with mutations in CDKL5. | Q51928093 | ||
| High throughput production of mouse monoclonal antibodies using antigen microarrays | Q61755547 | ||
| Widespread recombinase expression using FLPeR (flipper) mice | Q73266365 | ||
| Temporal aspects of contrast visual evoked potentials in the pigmented rat: effect of dark rearing | Q73348632 | ||
| Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment | Q34441265 | ||
| The relevance of individual genetic background and its role in animal models of epilepsy | Q35549275 | ||
| Dissecting MECP2 function in the central nervous system | Q36286552 | ||
| Ribosomal protein S6 phosphorylation: from protein synthesis to cell size. | Q36470315 | ||
| Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice. | Q36504423 | ||
| RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation | Q36745240 | ||
| The role of MeCP2 in the brain. | Q37896649 | ||
| A Cre/loxP-deleter transgenic line in mouse strain 129S1/SvImJ. | Q40744891 | ||
| TrkA activation in the rat visual cortex by antirat trkA IgG prevents the effect of monocular deprivation | Q43094500 | ||
| Presence of visual head tracking differentiates normal sighted from retinal degenerate mice | Q44002082 | ||
| Comparative study of brain morphology in Mecp2 mutant mouse models of Rett syndrome | Q46146028 | ||
| Dorsal telencephalon-specific expression of Cre recombinase in PAC transgenic mice. | Q47867280 | ||
| Organ growth in Rett syndrome: a postmortem examination analysis | Q48260356 | ||
| Early environmental enrichment moderates the behavioral and synaptic phenotype of MeCP2 null mice | Q48299153 | ||
| EEG gamma frequency and sleep-wake scoring in mice: comparing two types of supervised classifiers | Q48324515 | ||
| The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression | Q48667829 | ||
| Evidence for both neuronal cell autonomous and nonautonomous effects of methyl-CpG-binding protein 2 in the cerebral cortex of female mice with Mecp2 mutation | Q48789131 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | CDKL5 deficiency disorder | Q40739448 |
| P304 | page(s) | e91613 | |
| P577 | publication date | 2014-05-16 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Mapping pathological phenotypes in a mouse model of CDKL5 disorder | |
| P478 | volume | 9 |
| Q28079929 | A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons. |
| Q64039595 | AMPA receptor dysregulation and therapeutic interventions in a mouse model of CDKL5 Deficiency Disorder |
| Q92761256 | Altered NMDAR signaling underlies autistic-like features in mouse models of CDKL5 deficiency disorder |
| Q35915948 | CDKL5 and Shootin1 Interact and Concur in Regulating Neuronal Polarization |
| Q38946519 | CDKL5 deficiency entails sleep apneas in mice |
| Q39827058 | CDKL5 knockout leads to altered inhibitory transmission in the cerebellum of adult mice. |
| Q41109322 | CDKL5 localizes at the centrosome and midbody and is required for faithful cell division |
| Q36055559 | Characterisation of CDKL5 Transcript Isoforms in Human and Mouse |
| Q62084107 | Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics |
| Q30390885 | Comprehensive behavioral analysis of RNG105 (Caprin1) heterozygous mice: Reduced social interaction and attenuated response to novelty |
| Q53828453 | Comprehensive behavioral analysis of the Cdkl5 knockout mice revealed significant enhancement in anxiety- and fear-related behaviors and impairment in both acquisition and long-term retention of spatial reference memory. |
| Q59303931 | Expression pattern of cdkl5 during zebrafish early development: implications for use as model for atypical Rett syndrome |
| Q64078571 | Functional and Structural Impairments in the Perirhinal Cortex of a Mouse Model of CDKL5 Deficiency Disorder Are Rescued by a TrkB Agonist |
| Q48599692 | HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder |
| Q55436457 | Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder. |
| Q89460115 | Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons |
| Q39103694 | Lack of Cdkl5 Disrupts the Organization of Excitatory and Inhibitory Synapses and Parvalbumin Interneurons in the Primary Visual Cortex. |
| Q34097099 | Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling. |
| Q48183034 | Loss of CDKL5 in Glutamatergic Neurons Disrupts Hippocampal Microcircuitry and Leads to Memory Impairment in Mice. |
| Q47661198 | Mice lacking cyclin-dependent kinase-like 5 manifest autistic and ADHD-like behaviors |
| Q92782695 | Microtubules: A Key to Understand and Correct Neuronal Defects in CDKL5 Deficiency Disorder? |
| Q91678331 | Molecular and Synaptic Bases of CDKL5 Disorder |
| Q33752190 | Molecular and genetic insights into an infantile epileptic encephalopathy - CDKL5 disorder |
| Q57029718 | Neuron-Type Specific Loss of CDKL5 Leads to Alterations in mTOR Signaling and Synaptic Markers |
| Q92144190 | Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation |
| Q27308052 | Pathogenesis and new candidate treatments for infantile spasms and early life epileptic encephalopathies: A view from preclinical studies |
| Q92919056 | Reigning in Excitatory Signaling in CDKL5 Deficiency |
| Q26770762 | Ribosomal Protein S6 Phosphorylation in the Nervous System: From Regulation to Function |
| Q33762246 | Searching for biomarkers of CDKL5 disorder: early-onset visual impairment in CDKL5 mutant mice |
| Q92160931 | Site-specific abnormalities in the visual system of a mouse model of CDKL5 deficiency disorder |
| Q35080413 | Synaptic synthesis, dephosphorylation, and degradation: a novel paradigm for an activity-dependent neuronal control of CDKL5 |
| Q89596064 | The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo |
| Q55416149 | Utilizing Animal Models of Infantile Spasms. |
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