Human melanoma metastases demonstrate nonstochastic site-specific antigen heterogeneity that correlates with T-cell infiltration

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Human melanoma metastases demonstrate nonstochastic site-specific antigen heterogeneity that correlates with T-cell infiltration is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/1078-0432.CCR-13-2690
P932PMC publication ID4024351
P698PubMed publication ID24647571

P50authorSteven RosenbergQ2347448
Edmund K. BartlettQ40584715
Seth M SteinbergQ92007107
Francesco MarincolaQ107723823
P2093author name stringArmando C Filie
Donald E White
John R Wunderlich
Udai S Kammula
Andrea Abati
Patricia A Fetsch
Daniel J Stephens
P2860cites workCD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.Q24540429
Exome sequencing identifies recurrent somatic RAC1 mutations in melanomaQ24607661
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MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanomaQ24685652
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Signaling and transcriptional regulation in the neural crest-derived melanocyte lineage: interactions between KIT and MITFQ28143787
The distribution of secondary growths in cancer of the breast. 1889Q29614314
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicityQ29620119
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Heterogeneous expression of immunotherapy candidate proteins gp100, MART-1, and tyrosinase in human melanoma cell lines and in human melanocytic lesionsQ41097918
Human tumor antigens recognized by T cellsQ41196996
Analysis of expression of the melanoma-associated antigens MART-1 and gp100 in metastatic melanoma cell lines and in in situ lesions.Q41200467
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Potent selection of antigen loss variants of B16 melanoma following inflammatory killing of melanocytes in vivoQ45309151
Melanoma-associated antigen recognized by T cells (MART-1): the advent of a preferred immunocytochemical antibody for the diagnosis of metastatic malignant melanoma with fine-needle aspirationQ48252479
Expression of gp100, MART-1, tyrosinase, and S100 in paraffin-embedded primary melanomas and locoregional, lymph node, and visceral metastases: implications for diagnosis and immunotherapy. A study conducted by the EORTC Melanoma Cooperative GroupQ49042094
Metastasis results from preexisting variant cells within a malignant tumorQ67602509
A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude miceQ70935075
Horizontal gene transfer in glycosyl hydrolases inferred from codon usage in Escherichia coli and Bacillus subtilisQ72991207
Heterogeneous expression of melanoma-associated antigens and HLA-A2 in metastatic melanoma in vivoQ74185524
Tyrosinase immunoreactivity in fine-needle aspiration samples of metastatic malignant melanomaQ74246345
Comparison of immunohistochemical staining of the novel antibody melan-A with S100 protein and HMB-45 in malignant melanoma and melanoma variantsQ74447038
Melanoma antigen expression in serial fine-needle aspiration samples in patients with metastatic malignant melanoma participating in immunotherapy clinical trials: a preliminary lookQ77364702
Distinct role for CD8 T cells toward cutaneous tumors and visceral metastasesQ80241859
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)2607-2616
P577publication date2014-03-19
P1433published inClinical Cancer ResearchQ332253
P1476titleHuman melanoma metastases demonstrate nonstochastic site-specific antigen heterogeneity that correlates with T-cell infiltration
P478volume20

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cites work (P2860)
Q47614555Cell death and immunity in cancer: From danger signals to mimicry of pathogen defense responses.
Q36863359Identification of an Immunogenic Subset of Metastatic Uveal Melanoma
Q39281286Immunological metagene signatures derived from immunogenic cancer cell death associate with improved survival of patients with lung, breast or ovarian malignancies: A large-scale meta-analysis
Q33880126Location, location, location: The relationship of anatomic site, antigen expression, and T-cell infiltration in human melanoma metastases
Q38802594Melanoma Immunotherapy in Mice Using Genetically Engineered Pluripotent Stem Cells
Q41405130Melanoma cells homing to the brain: an in vitro model
Q35044333Persistence of CTL clones targeting melanocyte differentiation antigens was insufficient to mediate significant melanoma regression in humans

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