Steven Rosenberg

American cancer researcher

DBpedia resource is: http://dbpedia.org/resource/Steven_Rosenberg

Abstract is: Steven A. Rosenberg (born 2 August 1940) is an American cancer researcher and surgeon, chief of Surgery at the National Cancer Institute in Bethesda, Maryland and a Professor of Surgery at the Uniformed Services University of Health Sciences and the George Washington University School of Medicine and Health Sciences. He pioneered the development of immunotherapy that has resulted in the first effective immunotherapies and the development of gene therapy. He is the first researcher to successfully insert foreign genes into humans.

Born 1940-08-02 in New York City (Q60)

Steven Rosenberg is …
instance of (P31):
humanQ5

External links are
P2381Academic Tree ID6345
P3280BAnQ authority ID0000359613
P268Bibliothèque nationale de France ID12268111w
P8179Canadiana Name Authority IDncf10924921
P9984CANTIC ID981058610895006706
P11496CiNii Research ID1140000791782091008
P2163FAST ID41645
P646Freebase ID/m/0gpjyc
P227GND ID1232760110
P269IdRef ID031471501
P213ISNI0000000083590026
P11249KBR person ID14708700
P409Libraries Australia ID35939695
P244Library of Congress authority IDn79097023
P1284Munzinger person ID00000019902
P271NACSIS-CAT author IDDA00776150
P4619National Library of Brazil ID000337149
P8189National Library of Israel J9U ID987007456085805171
P5034National Library of Korea IDKAC201763705
P7699National Library of Lithuania IDLNB:CLCF;=r5
P950National Library of Spain IDXX861375
P1006Nationale Thesaurus voor Auteursnamen ID068118414
P349NDL Authority ID00474031
P691NL CR AUT IDnlk20040160833
P1015NORAF ID90093352
P1375NSK ID000307057
P1207NUKAT IDn02022629
P496ORCID iD0000-0002-8939-8910
P7293PLWABN ID9810636233905606
P3368Prabook ID1872307
P3065RERO ID (obsolete)02-A003760388
P3987SHARE Catalogue author ID101390
P11686University of Barcelona authority ID981058610895006706
P214VIAF ID315224699
P10832WorldCat Entities IDE39PBJfRFYxH6yh6qxp3wFQTHC

P512academic degreeDoctor of PhilosophyQ752297
P166award receivedKeio Medical Science PrizeQ1324940
William B. Coley AwardQ918979
Karl Landsteiner Memorial AwardQ1732108
Leopold Griffuel PrizeQ1879505
Massry PrizeQ1907790
Albany Medical Center PrizeQ2637278
National Medal of Technology and InnovationQ937629
Clarivate Citation LaureatesQ7795894
AACR Award for Lifetime Achievement in Cancer ResearchQ52413759
AACR-CRI Lloyd J. Old Award in Cancer ImmunologyQ52413917
Novartis Prize for Clinical ImmunologyQ56289445
Fellow of the AACR AcademyQ61636373
P27country of citizenshipUnited States of AmericaQ30
P1343described by sourceObálky knihQ67311526
MedvikQ99413897
P1889different fromSteven A. RosenbergQ63865665
P69educated atHarvard UniversityQ13371
Johns Hopkins UniversityQ193727
P108employerNational Cancer InstituteQ664846
George Washington UniversityQ432637
P734family nameRosenbergQ1159003
RosenbergQ1159003
RosenbergQ1159003
P101field of workoncologyQ162555
P735given name???Q17501985
???Q17501985
P1412languages spoken, written or signedEnglishQ1860
P1559name in native languageSteven Rosenberg
P106occupationsurgeonQ774306
university teacherQ1622272
immunologistQ12119633
oncologistQ16062369
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q39136403'Final common pathway' of human cancer immunotherapy: targeting random somatic mutations.
Q376148122D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system.
Q2855370331st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one
Q36943923A High-avidity WT1-reactive T-Cell Receptor Mediates Recognition of Peptide and Processed Antigen but not Naturally Occurring WT1-positive Tumor Cells
Q45892913A Phase I study of an HLA-DPB1*0401-restricted T cell receptor targeting MAGE-A3 for patients with metastatic cancers
Q90287047A Phase II Study of Tumor-infiltrating Lymphocyte Therapy for Human Papillomavirus-associated Epithelial Cancers
Q45863693A Pilot Trial of the Combination of Vemurafenib with Adoptive Cell Therapy in Patients with Metastatic Melanoma
Q56890830A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Effect of Nystatin on the Development of Oral Irritation in Patients Receiving High-Dose Intravenous Interleukin-2
Q40451831A Rapid Cell Expansion Process for Production of Engineered Autologous CAR-T Cell Therapies.
Q39621147A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer.
Q39785306A herceptin-based chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity
Q35632469A high molecular weight melanoma-associated antigen-specific chimeric antigen receptor redirects lymphocytes to target human melanomas
Q33917519A highly recurrent RPS27 5'UTR mutation in melanoma
Q69896756A large scale method of separating multiple lymphokines secreted by the murine EL-4 thymoma
Q36365851A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes
Q68892301A new approach to the therapy of cancer based on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2
Q34729692A novel chimeric antigen receptor against prostate stem cell antigen mediates tumor destruction in a humanized mouse model of pancreatic cancer.
Q39018359A novel murine T-cell receptor targeting NY-ESO-1.
Q33342339A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma
Q36299662A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer
Q36509683A pilot study of antiangiogenic therapy with bevacizumab and thalidomide in patients with metastatic renal cell carcinoma
Q67980070A pilot study of the combination of interleukin-2-based immunotherapy and radiation therapy
Q35182795A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response
Q68815180A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone
Q36430749A prospective analysis of positron emission tomography and conventional imaging for detection of stage IV metastatic melanoma in patients undergoing metastasectomy
Q72248479A prospective randomized trial evaluating colloid versus crystalloid resuscitation in the treatment of the vascular leak syndrome associated with interleukin-2 therapy
Q73665603A prospective, randomized, double-blind, placebo-controlled trial evaluating the effect of nystatin on the development of oral irritation in patients receiving high-dose intravenous interleukin-2
Q53905620A randomized double-blinded comparison of the antiemetic efficacy of ondansetron and droperidol in patients receiving high-dose interleukin-2.
Q36509678A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
Q37358371A simple and effective method to generate lentiviral vectors for ex vivo gene delivery to mature human peripheral blood lymphocytes
Q51050000A simplified method for the clinical-scale generation of central memory-like CD8+ T cells after transduction with lentiviral vectors encoding antitumor antigen T-cell receptors.
Q34512762A summary of the results of a review of 405 patients with non-Hodgkin's lymphoma at Stanford University
Q40831581A tumor-infiltrating lymphocyte from a melanoma metastasis with decreased expression of melanoma differentiation antigens recognizes MAGE-12.
Q41295186Acquired erythropoietin responsiveness of interleukin-2-dependent T lymphocytes retrovirally transduced with genes encoding chimeric erythropoietin/interleukin-2 receptors
Q33831940Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells
Q37454925Acute and long-term effects on limb function of combined modality limb sparing therapy for extremity soft tissue sarcoma
Q33299427Administration of a CD25-directed immunotoxin, LMB-2, to patients with metastatic melanoma induces a selective partial reduction in regulatory T cells in vivo
Q38576508Adoptive Cell Therapy--Tumor-Infiltrating Lymphocytes, T-Cell Receptors, and Chimeric Antigen Receptors.
Q37129943Adoptive cell therapy for patients with melanoma, using tumor-infiltrating lymphocytes genetically engineered to secrete interleukin-2.
Q24644442Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens
Q36283034Adoptive cell therapy for the treatment of patients with metastatic melanoma
Q37778694Adoptive cell therapy: genetic modification to redirect effector cell specificity.
Q34043643Adoptive cell transfer as personalized immunotherapy for human cancer
Q38146713Adoptive cell transfer for patients with metastatic melanoma: the potential and promise of cancer immunotherapy.
Q24548019Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
Q24644774Adoptive cell transfer: a clinical path to effective cancer immunotherapy
Q24546258Adoptive immunotherapy for cancer: building on success
Q28262548Adoptive immunotherapy for cancer: harnessing the T cell response
Q68940777Adoptive immunotherapy of a newly induced sarcoma: immunologic characteristics of effector cells
Q43707846Adoptive immunotherapy of a syngeneic murine leukemia with a tumor-specific cytotoxic T cell clone and recombinant human interleukin 2: correlation with clonal IL 2 receptor expression
Q71002947Adoptive immunotherapy of established syngeneic solid tumors: role of T lymphoid subpopulations
Q69875757Adoptive immunotherapy of murine hepatic metastases with lymphokine activated killer (LAK) cells and recombinant interleukin 2 (RIL 2) can mediate the regression of both immunogenic and nonimmunogenic sarcomas and an adenocarcinoma
Q40893119Adoptive immunotherapy of renal cell carcinoma: studies from the Surgery Branch, National Cancer Institute
Q37002020Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers.
Q35269067Adoptive transfer of autologous natural killer cells leads to high levels of circulating natural killer cells but does not mediate tumor regression
Q34310912Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells
Q45812987Adoptive transfer of tumor infiltrating lymphocytes for metastatic cervical cancer
Q33261122Adoptive transfer of vaccine-induced peripheral blood mononuclear cells to patients with metastatic melanoma following lymphodepletion
Q35210008Adoptive-cell-transfer therapy for the treatment of patients with cancer
Q52082723Adoptively Transferred Tumor-Infiltrating Lymphocytes Can Cure Established Metastatic Tumor in Mice and Persist Long-Term In Vivo as Functional Memory T Lymphocytes
Q37389018Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity.
Q45893625Adoptively transferred tumor-infiltrating T cells target somatic cancer mutations in a human papillomavirus+ cancer patient with complete tumor regression
Q35257907Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics.
Q35904666Allogeneic T Cells That Express an Anti-CD19 Chimeric Antigen Receptor Induce Remissions of B-Cell Malignancies That Progress After Allogeneic Hematopoietic Stem-Cell Transplantation Without Causing Graft-Versus-Host Disease
Q34657707Altered CD8(+) T-cell responses when immunizing with multiepitope peptide vaccines
Q41003839Alternating chemotherapy and irradiation in the treatment of advanced Hodgkin's disease
Q45875006An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors.
Q34192290An antigenic peptide produced by reverse splicing and double asparagine deamidation
Q44635436An improved method for growing murine tumor-infiltrating lymphocytes with in vivo antitumor activity
Q33501570An ongoing prospective randomized comparison of interleukin-2 regimens for the treatment of metastatic renal cell cancer
Q70805193Analysis of cytokine secretion by melanoma-specific CD4+ T lymphocytes
Q41200467Analysis of expression of the melanoma-associated antigens MART-1 and gp100 in metastatic melanoma cell lines and in in situ lesions.
Q34657684Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade
Q35012297Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma
Q37356835Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma
Q27851483Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.
Q34031748Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer
Q68814698Antibody-dependent cellular cytotoxicity mediated by murine lymphocytes activated in recombinant interleukin 2
Q93037188Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens
Q41239385Antigen-specific tumor vaccines. Development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy.
Q36700826Antitumor effects in mice of the intravenous injection of attenuated Salmonella typhimurium
Q68805101Antitumor efficacy of lymphokine-activated killer cells and recombinant interleukin 2 in vivo: successful immunotherapy of established pulmonary metastases from weakly immunogenic and nonimmunogenic murine tumors of three district histological types
Q54433454Antitumor efficacy of lymphokine-activated killer cells and recombinant interleukin-2 in vivo: survival benefit and mechanisms of tumor escape in mice undergoing immunotherapy.
Q34954883Assessment of ovarian function after preparative chemotherapy and total body radiation for adoptive cell therapy
Q49266293Audiovestibular dysfunction associated with adoptive cell immunotherapy for melanoma.
Q69636948Augmentation of antitumor efficacy by the combination of recombinant tumor necrosis factor and chemotherapeutic agents in vivo
Q35382043Augmented lymphocyte expansion from solid tumors with engineered cells for costimulatory enhancement
Q64105836Author Correction: Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells
Q64112309Author Correction: RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells
Q34657638Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.
Q29620717B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
Q92060568BRAF Inhibition: Bridge or Boost to T-cell Therapy?
Q36327125Bcl-2 overexpression enhances tumor-specific T-cell survival
Q34703616Bedside to bench and back again: how animal models are guiding the development of new immunotherapies for cancer
Q41683954Biological and antitumor effects of recombinant human macrophage colony-stimulating factor in mice
Q45858725Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase.
Q42649114CARs on track in the clinic
Q72668269CD4+ T-cells from mice immunized to syngeneic sarcomas recognize distinct, non-shared tumor antigens
Q34299986CD8+ Enriched “Young” Tumor Infiltrating Lymphocytes Can Mediate Regression of Metastatic Melanoma
Q24540429CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.
Q68545128CEPP(B): an effective and well-tolerated regimen in poor-risk, aggressive non-Hodgkin's lymphoma
Q35871798CTLA-4 blockade with ipilimumab: long-term follow-up of 177 patients with metastatic melanoma
Q35190928CTLA-4 dysregulation of self/tumor-reactive CD8+ T-cell function is CD4+ T-cell dependent.
Q73900121Calcium ionophore-treated peripheral blood monocytes and dendritic cells rapidly display characteristics of activated dendritic cells
Q81925442Cancer immunotherapy
Q57152489Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer
Q39733329Cancer immunotherapy using interleukin-2 and interleukin-2-activated lymphocytes
Q24548229Cancer immunotherapy: moving beyond current vaccines
Q24676216Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
Q24679736Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
Q36637039Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
Q24654976Cancer regression in patients after transfer of genetically engineered lymphocytes
Q37570109Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes
Q35573819Cell transfer therapy for cancer: lessons from sequential treatments of a patient with metastatic melanoma
Q68698359Cellular immunotherapy of cancer
Q67881119Cellular mechanisms of the antitumor activity of recombinant IL-6 in mice
Q24530100Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells
Q41766668Characterization of Lymphocytes Infiltrating Human Breast Cancer, Specific Immune Reactivity Detected by Measuring Cytokine Secretion
Q70387548Characterization of Postsplenectomy Bacteremia among Patients with and without Lymphoma
Q36372755Characterization of T-cell receptors directed against HLA-A*01-restricted and C*07-restricted epitopes of MAGE-A3 and MAGE-A12.
Q38854579Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer.
Q36326582Characterization of genetically modified T-cell receptors that recognize the CEA:691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells
Q41554132Characterization of human tumor cell lines transduced with the cDNA encoding either tumor necrosis factor alpha (TNF-a) or interleukin-2 (IL-2).
Q41369700Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen.
Q71728277Characterization of the lysis of fresh human solid tumors by autologous lymphocytes activated in vitro with phytohemagglutinin
Q40808854Chemotherapy of the non-Hodgkin's lymphomas: the Stanford experience
Q34041792Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor
Q36079820Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serum
Q39534880Circulating Tumor DNA as an Early Indicator of Response to T-cell Transfer Immunotherapy in Metastatic Melanoma
Q36757025Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.
Q67674180Clinical and surgical (laparotomy) evaluation of patients with non-Hodgkin's lymphomas
Q36110862Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE® bioreactor
Q55638863Clinical scale zinc finger nuclease (ZFN)-driven gene-editing of PD-1 in tumor infiltrating lymphocytes (TIL) for the potential treatment of metastatic melanoma.
Q36291092Clinical trials in the non-Hodgkin's lymphomata at Stanford University experimental design and preliminary results
Q68925034Clinical trials with IL-2
Q36102927Clinical-scale lentiviral vector transduction of PBL for TCR gene therapy and potential for expression in less-differentiated cells
Q36984473Collapse of the tumor stroma is triggered by IL-12 induction of Fas.
Q53712809Combination chemotherapy and radiotherapy for Hodgkin's disease
Q69736492Combination cytokine immunotherapy with tumor necrosis factor alpha, interleukin 2, and alpha-interferon and its synergistic antitumor effects in mice
Q71659952Combination therapy with interferon-gamma and interleukin-2 for the treatment of metastatic melanoma
Q64122192Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma
Q68090211Combined effects of chemotherapy and interleukin 2 in the therapy of mice with advanced pulmonary tumors
Q47097618Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells.
Q40808905Combined modality therapy in malignant lymphomas
Q39617663Combined modality therapy of Hodgkin's disease.A report on the stanford trials
Q42622588Common expression of melanoma tumor-associated antigens recognized by human tumor infiltrating lymphocytes: analysis by human lymphocyte antigen restriction
Q34420417Comparative exome sequencing of metastatic lesions provides insights into the mutational progression of melanoma
Q68906281Comparative studies of the long-term growth of lymphocytes from tumor infiltrates, tumor-draining lymph nodes, and peripheral blood by repeated in vitro stimulation with autologous tumor
Q73062516Comparison between conventional salvage therapy and high-dose therapy with autografting for recurrent or refractory Hodgkin's disease
Q40280069Comparison of common gamma-chain cytokines, interleukin-2, interleukin-7, and interleukin-15 for the in vitro generation of human tumor-reactive T lymphocytes for adoptive cell transfer therapy
Q35563824Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells.
Q71009588Computed tomography, lymphography, and staging laparotomy: correlations in initial staging of Hodgkin disease
Q34025234Considerations for the clinical application of chimeric antigen receptor T cells: observations from a recombinant DNA Advisory Committee Symposium held June 15, 2010
Q37354362Construction and preclinical evaluation of an anti-CD19 chimeric antigen receptor
Q43161957Continuous intravenous administration of live genetically modified salmonella typhimurium in patients with metastatic melanoma
Q33499384Correlates of response to IL-2 therapy in patients treated for metastatic renal cancer and melanoma.
Q53545190Curative intravenous adoptive immunotherapy of Meth A murine sarcoma. A histologic and immunohistochemical assessment.
Q36328394Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy
Q67666264Cytokine regulation of tumor necrosis factor-alpha and -beta (lymphotoxin)-messenger RNA expression in human peripheral blood mononuclear cells
Q35839860Cytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 gene
Q69178157Cytokines alter target cell susceptibility to lysis. II. Evaluation of tumor infiltrating lymphocytes
Q46618196Cytokines alter target cell susceptibility to lysis: I. Evaluation of non-major histocompatibility complex-restricted effectors reveals differential effects on natural and lymphokine-activated killing
Q56903260Cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma: a new cause of uveitis
Q36299657Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer
Q69735294Decrease in interleukin 2-induced vascular leakage in the lungs of mice by administration of recombinant interleukin 1 alpha in vivo
Q102074966Defining best practices for tissue procurement in immuno-oncology clinical trials: consensus statement from the Society for Immunotherapy of Cancer Surgery Committee
Q40627166Delata-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate. A prospective, randomized evaluation
Q39502796Delayed reactions to contrast media after interleukin-2 immunotherapy
Q36380718Dendritic cells retrovirally transduced with a model antigen gene are therapeutically effective against established pulmonary metastases
Q35223241Determinants of successful CD8+ T-cell adoptive immunotherapy for large established tumors in mice
Q35135031Development of a T cell receptor targeting an HLA-A*0201 restricted epitope from the cancer-testis antigen SSX2 for adoptive immunotherapy of cancer
Q45238704Development of an automated closed system for generation of human lymphokine-activated killer (LAK) cells for use in adoptive immunotherapy
Q34678708Development of human anti-murine T-cell receptor antibodies in both responding and nonresponding patients enrolled in TCR gene therapy trials
Q72111537Development of long-term cell lines and lymphoid clones reactive against murine and human tumors: a new approach to the adoptive immunotherapy of cancer
Q69994353Differences in the effects of host suppression on the adoptive immunotherapy of subcutaneous and visceral tumors
Q35638553Different adjuvanticity of incomplete freund's adjuvant derived from beef or vegetable components in melanoma patients immunized with a peptide vaccine.
Q61692954Differential Anti-MART-1/MelanA CTL Activity in Peripheral Blood of HLA-A2 Melanoma Patients in Comparison to Healthy Donors
Q71699059Differential anti-MART-1/MelanA CTL activity in peripheral blood of HLA-A2 melanoma patients in comparison to healthy donors: evidence of in vivo priming by tumor cells
Q45907700Discovery and characterization of an immunogenic neoantigen in a patient with metastatic triple negative breast cancer.
Q43933734Disseminated human malignant melanoma in congenitally immune-deficient (bg/nu/xid) mice
Q45892785Diversity of mutated antigen recognition by tumor infiltrating lymphocytes from patients with metastatic melanoma
Q37390239Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation
Q40411216Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting.
Q41958978Durable Complete Response from Metastatic Melanoma after Transfer of Autologous T Cells Recognizing 10 Mutated Tumor Antigens
Q45893979Durable complete response in a patient with metastatic melanoma following adoptive transfer of autologous T cells recognizing 10 mutated tumor antigens.
Q24596055Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
Q37618652EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss.
Q68818529Effect of anti-B16 melanoma monoclonal antibody on established murine B16 melanoma liver metastases
Q43745067Effect of combined therapy with lymphokine-activated killer cells, interleukin 2 and specific monoclonal antibody on established B16 melanoma lung metastases.
Q68805123Effect of corticosteroid on the antitumor activity of lymphokine-activated killer cells and interleukin 2 in mice
Q40663693Effect of hydration on plasma-methotrexate levels
Q68805126Effect of immunotherapy with allogeneic lymphokine-activated killer cells and recombinant interleukin 2 on established pulmonary and hepatic metastases in mice
Q36693023Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity
Q71566426Effects of high-dose methotrexate and vincristine on ovarian and testicular functions in patients undergoing postoperative adjuvant treatment of osteosarcoma
Q42066596Effects of murine tumor class I major histocompatibility complex expression on antitumor activity of tumor-infiltrating lymphocytes
Q71578923Effects of postoperative adjuvant chemotherapy and radiotherapy on ovarian function in women undergoing treatment for soft tissue sarcoma
Q44108177Efficacy of adjuvant radiation therapy in the treatment of soft tissue sarcoma of the extremity: 20-year follow-up of a randomized prospective trial
Q33851742Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions.
Q77929305Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity
Q68128494Endothelial activation during interleukin 2 immunotherapy. A possible mechanism for the vascular leak syndrome
Q55086081Engineered T cells targeting E7 mediate regression of human papillomavirus cancers in a murine model.
Q34624124Engineering improved T cell receptors using an alanine-scan guided T cell display selection system
Q46143578Engineering the immune response to "self" for effective cancer immunotherapy
Q36286122Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.
Q36286127Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability
Q57029270Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy
Q92782148Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models
Q36215613Enhanced receptor expression and in vitro effector function of a murine-human hybrid MART-1-reactive T cell receptor following a rapid expansion
Q39704543Enrichment of CD8+ cells from melanoma tumor-infiltrating lymphocyte cultures reveals tumor reactivity for use in adoptive cell therapy.
Q34567635Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4
Q34360292Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
Q50917597Eradication of a disseminated syngeneic mouse lymphoma by systemic adoptive transfer of immune lymphocytes and its dependence upon a host component(s).
Q40585962Evaluation of computed tomography in the detection of pulmonary metastases.A prospective study
Q36294815Evaluation of prime/boost regimens using recombinant poxvirus/tyrosinase vaccines for the treatment of patients with metastatic melanoma
Q35982211Evaluation of γ-retroviral vectors that mediate the inducible expression of IL-12 for clinical application
Q72873162Evidence for an orderly progression in the spread of Hodgkin's disease
Q69873472Evidence that lymphokine-activated killer cells and natural killer cells are distinct based on an analysis of congenitally immunodeficient mice
Q92580838Exome Sequencing of ABCB5 Identifies Recurrent Melanoma Mutations that Result in Increased Proliferative and Invasive Capacities
Q35179796Exome sequencing identifies GRIN2A as frequently mutated in melanoma
Q36037070Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.
Q73236549Expansion and characterization of T cells transduced with a chimeric receptor against ovarian cancer
Q44098509Expansion of human tumor infiltrating lymphocytes for use in immunotherapy trials
Q70278394Experimental and clinical studies with intraoperative radiotherapy
Q53182179Expression of MAGE-A and NY-ESO-1 in Primary and Metastatic Cancers.
Q37625469Expression of New York esophageal squamous cell carcinoma-1 in primary and metastatic melanoma.
Q36471604Expression of a "self-"antigen by human tumor cells enhances tumor antigen-specific CD4(+) T-cell function.
Q37113080Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytes
Q53735726Extended-field radiation therapy in Hodgkin's disease. A progress report.
Q72873174Extended-field radical radiotherapy in advanced Hodgkin's disease: short-term results of 2 randomized clinical trials
Q53816438Extralymphatic Hodgkin's disease. Prognosis and response to therapy.
Q36178641Extrathymic generation of tumor-specific T cells from genetically engineered human hematopoietic stem cells via Notch signaling
Q68895797Extravasation of intravascular fluid mediated by the systemic administration of recombinant interleukin 2
Q41980691Extremity soft tissue sarcomas: analysis of prognostic variables in 300 cases and evaluation of tumor necrosis as a factor in stratifying higher-grade sarcomas
Q34197717FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions
Q43458837Factors predicting survival in adults with stage I and II large-cell lymphoma treated with primary radiation therapy
Q70771870Female Reproductive Potential after Treatment for Hodgkin's Disease
Q36835348Frequency of MART-1/MelanA and gp100/PMel17-specific T cells in tumor metastases and cultured tumor-infiltrating lymphocytes
Q37309027Frequent mutations in the MITF pathway in melanoma
Q51084293Functional analysis of antigen-specific T lymphocytes by serial measurement of gene expression in peripheral blood mononuclear cells and tumor specimens.
Q77436967Functional dissociation between local and systemic immune response during anti-melanoma peptide vaccination
Q36908627Functional heterogeneity of vaccine-induced CD8(+) T cells
Q37185223Gene expression profiling using nanostring digital RNA counting to identify potential target antigens for melanoma immunotherapy
Q34245416Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice
Q24623215Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
Q34354588Gene transfer into humans--immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction
Q36327157Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes
Q70030313Generation from tumor-bearing mice of lymphocytes with in vivo therapeutic efficacy
Q36924658Generation of NY-ESO-1-specific CD4+ and CD8+ T cells by a single peptide with dual MHC class I and class II specificities: a new strategy for vaccine design.
Q72111115Generation of long-term T-lymphoid cell lines with specific cytotoxic reactivity for a syngeneic murine lymphoma
Q71006725Generation of lytic and proliferative lymphoid clones to syngeneic tumor: in vitro and in vivo studies
Q36551911Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients
Q41380419Generation of tumor-specific CTLs from melanoma patients by using peripheral blood stimulated with allogeneic melanoma tumor cell lines. Fine specificity and MART-1 melanoma antigen recognition.
Q35001971Genetic engineering of murine CD8+ and CD4+ T cells for preclinical adoptive immunotherapy studies.
Q46576306Genetic inference of immune responsiveness of melanoma cancer patients to TIL therapy
Q34703587Glucocorticoids do not inhibit antitumor activity of activated CD8+ T cells
Q44933177HLA association with response and toxicity in melanoma patients treated with interleukin 2-based immunotherapy
Q72185983Helper T cells infiltrating human renal cell carcinomas have the phenotype of activated memory-like T lymphocytes
Q33452632Hematologic effects of immunotherapy with lymphokine-activated killer cells and recombinant interleukin-2 in cancer patients.
Q67700700Hematologic neoplasia in patients treated for Hodgkin's disease
Q35613477Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells
Q54240398Hemodynamic effects of the administration of tumor-infiltrating lymphocytes to cancer patients.
Q44397830Heterogeneity of lymphokine-activated killer cells induced by IL-2. Separate lymphoid subpopulations lyse tumor, allogeneic blasts, and modified syngeneic blasts
Q40978441High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy.
Q36471584High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens
Q45893237High frequency CD8+PD-1+ TCR clonotypes isolated from fresh melanomas display anti-tumor activity
Q33303162High-affinity TCRs generated by phage display provide CD4+ T cells with the ability to recognize and kill tumor cell lines.
Q95932162High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D
Q36363721High-dose interleukin-2 for the treatment of metastatic renal cell carcinoma : a retrospective analysis of response and survival in patients treated in the surgery branch at the National Cancer Institute between 1986 and 2006.
Q43518310High-dose therapy and autologous bone marrow transplantation for follicular lymphoma in first complete or partial remission: results of a phase II clinical trial
Q34657652High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation
Q46507832Highlights of the society for immunotherapy of cancer (SITC) 27th annual meeting
Q41613178Hodgkin's disease, stages I and II occurring below the diaphragm
Q35789284Human CD4+ T cells specifically recognize a shared melanoma-associated antigen encoded by the tyrosinase gene
Q34557953Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy.
Q46204344Human lymphokine-activated killer cells: further isolation and characterization of the precursor and effector cell
Q41018130Human melanoma antigens recognized by T lymphocytes
Q33624972Human melanoma metastases demonstrate nonstochastic site-specific antigen heterogeneity that correlates with T-cell infiltration
Q69613975Human tumor infiltrating lymphocytes. Analysis of lymphokine mRNA expression and relevance to cancer immunotherapy
Q36908547Hybrids of dendritic cells and tumor cells generated by electrofusion simultaneously present immunodominant epitopes from multiple human tumor-associated antigens in the context of MHC class I and class II molecules
Q34330224IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain
Q35578622IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors.
Q24621753IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells
Q34657691IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients
Q36327148IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells
Q36677310IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy
Q68456823IL-2-based immunotherapy alters circulating neutrophil Fc receptor expression and chemotaxis
Q41841133IL-4 regulates IL-2 induction of lymphokine-activated killer activity from human lymphocytes
Q69735138IL-4 regulation of murine lymphokine-activated killer activity in vitro. Effects on the IL-2-induced expansion, cytotoxicity, and phenotype of lymphokine-activated killer effectors
Q69735865IL-6/IFN-beta-2 as a circulating hormone. Induction by cytokine administration in humans
Q24546362IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells
Q39664105Identification and characterization of a tumor infiltrating CD56(+)/CD16 (-) NK cell subset with specificity for pancreatic and prostate cancer cell lines.
Q36908561Identification of BING-4 cancer antigen translated from an alternative open reading frame of a gene in the extended MHC class II region using lymphocytes from a patient with a durable complete regression following immunotherapy
Q42674567Identification of MART-1-specific T-cell receptors: T cells utilizing distinct T-cell receptor variable and joining regions recognize the same tumor epitope
Q91623677Identification of Neoantigen-Reactive Tumor-Infiltrating Lymphocytes in Primary Bladder Cancer
Q24649346Identification of a colorectal tumor-associated antigen (COA-1) recognized by CD4(+) T lymphocytes
Q36364355Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes
Q42651562Identification of a new shared HLA-A2.1 restricted epitope from the melanoma antigen tyrosinase
Q77536089Identification of a shared HLA-A*0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2)
Q41321782Identification of a tyrosinase epitope recognized by HLA-A24-restricted, tumor-infiltrating lymphocytes.
Q70341820Identification of cellular mechanisms operational in vivo during the regression of established pulmonary metastases by the systemic administration of high-dose recombinant interleukin 2
Q36713763Identification of endogenous HLA-A2-restricted reactivity against shared melanoma antigens in patients using the quantitative real-time polymerase chain reaction
Q36509702Identification of multiple antigens recognized by tumor-infiltrating lymphocytes from a single patient: tumor escape by antigen loss and loss of MHC expression
Q45893772Identification of mutation-specific tumor infiltrating lymphocytes from metastatic ovarian cancer
Q44999145Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma.
Q36363449Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes
Q41099384Identification of tumor-regression antigens in melanoma.
Q36376523Identification of tyrosinase-related protein 2 as a tumor rejection antigen for the B16 melanoma
Q41825723Identification of unique murine tumor associated antigens by tumor infiltrating lymphocytes using tumor specific secretion of interferon-gamma and tumor necrosis factor
Q98614792Identifying and Targeting Human Tumor Antigens for T Cell-Based Immunotherapy of Solid Tumors
Q57118558Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer
Q36907938Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
Q71614134Immunization against epitopes in the human melanoma antigen gp100 following patient immunization with synthetic peptides
Q36430745Immunization of HLA-A*0201 and/or HLA-DPbeta1*04 patients with metastatic melanoma using epitopes from the NY-ESO-1 antigen
Q77552569Immunization of patients with melanoma peptide vaccines: immunologic assessment using the ELISPOT assay
Q35190921Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens
Q36642248Immunization of patients with the hTERT:540-548 peptide induces peptide-reactive T lymphocytes that do not recognize tumors endogenously expressing telomerase
Q38823554Immunogenicity of somatic mutations in human gastrointestinal cancers.
Q69383998Immunohistochemical correlates of response to recombinant interleukin-2-based immunotherapy in humans
Q72991676Immunohistologic responses within dermal metastatic melanoma lesions of patients treated with a synthetic peptide vaccine
Q91311678Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer
Q89722643Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma
Q41732697Immunoselection of a human melanoma resistant to specific lysis by autologous tumor-infiltrating lymphocytes. Possible mechanisms for immunotherapeutic failures
Q34219970Immunotherapy for metastatic solid cancers
Q69906777Immunotherapy of cancer with lymphokine-activated killer cells and recombinant interleukin-2
Q68796572Immunotherapy of murine sarcomas using lymphokine activated killer cells: optimization of the schedule and route of administration of recombinant interleukin-2
Q48036736Immunotherapy: The path to win the war on cancer?
Q96639706Impact of Cysteine Residues on MHC Binding Predictions and Recognition by Tumor-Reactive T Cells
Q84559560Impact of a recombinant fowlpox vaccine on the efficacy of adoptive cell therapy with tumor infiltrating lymphocytes in a patient with metastatic melanoma
Q67315674Impact of salvage treatment on initial relapses in patients with Hodgkin disease, stages I-III
Q45767602Improved gene transfer into human lymphocytes using retroviruses with the gibbon ape leukemia virus envelope
Q71527769Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues
Q34757266Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment
Q72858702In search of an effective antiemetic: a nusring staff participates in marijuana research
Q41719598In vitro and in vivo antitumor properties of a T-cell clone generated from murine tumor-infiltrating lymphocytes
Q70327210In vitro differentiation of T-cells capable of mediating the regression of established syngeneic tumors in mice
Q72133294In vitro growth of cytotoxic human lymphocytes. II. Use of T cell growth factor (TCGF) to clone human T cells
Q70545916In vitro growth of cytotoxic human lymphocytes. III. The preparation of lectin-free T cell growth factor (TCGF) and an analysis of its activity
Q53576503In vitro growth of murine T cells. V. The isolation and growth of lymphoid cells infiltrating syngeneic solid tumors.
Q70161150In vitro growth of murine T cells. VI. Accelerated skin graft rejection caused by adoptively transferred cells expanded in T cell growth factor
Q43774102In vitro sensitization and expansion with viable tumor cells and interleukin 2 in the generation of specific therapeutic effector cells
Q68888616In vivo administration of interferon alpha and interleukin 2 induces proliferation of lymphoid cells in the organs of mice
Q43603587In vivo administration of purified Jurkat-derived interleukin 2 in mice
Q40821886In vivo administration of purified human interleukin 2. I. Half-life and immunologic effects of the Jurkat cell line-derived interleukin 2.
Q40815147In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2.
Q70169536In vivo administration of purified human interleukin-2 to patients with cancer: development of interleukin-2 receptor positive cells and circulating soluble interleukin-2 receptors following interleukin-2 administration
Q68017292In vivo administration of recombinant macrophage colony-stimulating factor induces macrophage-mediated antibody-dependent cytotoxicity of tumor cells
Q71887324In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes
Q44233004In vivo antitumor activity of tumor-infiltrating lymphocytes expanded in recombinant interleukin-2.
Q69205653In vivo induction of IL-6 by administration of exogenous cytokines and detection of de novo serum levels of IL-6 in tumor-bearing mice
Q70176041In vivo proliferation of adoptively transferred tumor-infiltrating lymphocytes in mice
Q34943798Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma
Q36144729Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen.
Q33282703Inability to mediate prolonged reduction of regulatory T Cells after transfer of autologous CD25-depleted PBMC and interleukin-2 after lymphodepleting chemotherapy
Q35594089Increased intensity lymphodepletion and adoptive immunotherapy--how far can we go?
Q35638571Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells
Q73202067Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression
Q59400469Individual cultures of melanoma tumor infiltrating lymphocytes possess distinct patterns of reactivity with mutated antigens identified by whole exome sequencing of autologous tumors
Q36509692Induction of CD4+ Th1 lymphocytes that recognize known and novel class II MHC restricted epitopes from the melanoma antigen gp100 by stimulation with recombinant protein
Q43560580Induction of antibody-dependent cellular cytotoxicity in vivo by IFN-alpha and its antitumor efficacy against established B16 melanoma liver metastases when combined with specific anti-B16 monoclonal antibody
Q45040842Induction of endogenous cytokine-mRNA in circulating peripheral blood mononuclear cells by IL-2 administration to cancer patients.
Q72989651Induction of melanoma reactive T cells by stimulator cells expressing melanoma epitope-major histocompatibility complex class I fusion proteins
Q44700343Initial relapse in previously treated Hodgkin's disease—II retrograde transdiaphragmatic extension
Q43712789Initial relapses in previously treated Hodgkin's disease. I. Results of second treatment
Q39650015Intercurrent death after Hodgkin disease therapy in radiotherapy and adjuvant MOPP trials
Q68099918Interleukin 2 and psoriasis
Q68090217Interleukin 2 expanded tumor-infiltrating lymphocytes in human renal cell cancer: isolation, characterization, and antitumor activity
Q36355725Interleukin 4 promotes the growth of tumor-infiltrating lymphocytes cytotoxic for human autologous melanoma
Q77914278Interleukin-2 based immunotherapy for metastatic renal cell carcinoma with the kidney in place
Q41392239Interleukin-2-transduced lymphocytes grow in an autocrine fashion and remain responsive to antigen.
Q36327129Intralymphatic dendritic cell vaccination induces tumor antigen-specific, skin-homing T lymphocytes
Q36259372Intrapatient dose escalation of anti-CTLA-4 antibody in patients with metastatic melanoma
Q40803152Intraperitoneal administration of interleukin-2 in patients with cancer
Q55485579Intratumoral LAK cell and interleukin-2 therapy of human gliomas.
Q34827147In vitro generated anti-tumor T lymphocytes exhibit distinct subsets mimicking in vivo antigen-experienced cells.
Q34720087Ipilimumab (anti-CTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis
Q34982519Irradiation enhances human T-cell function by upregulating CD70 expression on antigen-presenting cells in vitro
Q37100031Isolation and Characterization of an HLA-DPB1*04: 01-restricted MAGE-A3 T-Cell Receptor for Cancer Immunotherapy
Q45797575Isolation of T cell receptors specifically reactive with mutated tumor associated antigens
Q38797183Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 Expression.
Q36165605Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes
Q38714331LIGHT Elevation Enhances Immune Eradication of Colon Cancer Metastases
Q74130857Lack of retroperitoneal lymphadenopathy predicts survival of patients with metastatic renal cell carcinoma
Q37373008Lack of specific gamma-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation
Q40242985Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer
Q44715013Large scale production of human lymphokine activated killer cells for use in adoptive immunotherapy
Q34657644Large-scale depletion of CD25+ regulatory T cells from patient leukapheresis samples
Q33688441Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes
Q36057563Levels of peripheral CD4(+)FoxP3(+) regulatory T cells are negatively associated with clinical response to adoptive immunotherapy of human cancer.
Q39779492Limb-sparing surgery for soft tissue sarcomas: wound related morbidity in patients undergoing wide local excision.
Q45888653Liver resection for metastatic melanoma with postoperative tumor-infiltrating lymphocyte therapy.
Q50061565Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice.
Q40095482Long-Duration Complete Remissions of Diffuse Large B Cell Lymphoma after Anti-CD19 Chimeric Antigen Receptor T Cell Therapy
Q100457008Long-Term Follow-Up of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy
Q40785085Long-term outcome in 87 patients with low-grade soft-tissue sarcoma
Q44681853Long-term survival of adoptively transferred tumor-infiltrating lymphocytes in mice.
Q37129939Loss of S100 antigenicity in metastatic melanoma
Q72085643Lymphoblastic lymphoma in adults: results of a pilot protocol
Q70090680Lymphokine-activated killer (LAK) cell phenomenon. IV. Lysis by LAK cell clones of fresh human tumor cells from autologous and multiple allogeneic tumors
Q45111534Lymphokine-activated killer (LAK) cells. Analysis of factors relevant to the immunotherapy of human cancer
Q54474925Lymphokine-activated killer cells: lysis of fresh syngeneic natural killer-resistant murine tumor cells by lymphocytes cultured in interleukin 2.
Q50034163Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels.
Q72098225Lysis of fresh and cultured autologous tumor by human lymphocytes cultured in T-cell growth factor
Q70282589Lysis of fresh human solid tumors by autologous lymphocytes activated in vitro with lectins
Q54486584Lysis of fresh natural killer-resistant tumor cells by lectin-activated syngeneic and allogeneic murine splenocytes.
Q70663523Lysis of human solid tumors by autologous cells sensitized in vitro to alloantigens
Q36361920Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor gamma chain
Q36796813MAGE-A is More Highly Expressed Than NY-ESO-1 in a Systematic Immunohistochemical Analysis of 3668 Cases
Q73336748MHC class I-restricted recognition of a melanoma antigen by a human CD4+ tumor infiltrating lymphocyte
Q34050163MHC-I-restricted melanoma antigen specific TCR-engineered human CD4+ T cells exhibit multifunctional effector and helper responses, in vitro
Q53735871MOPP chemotherapy for advanced Hodgkin's disease. Prognostic factors in 81 patients.
Q68786760Manipulation of oxygen radical-scavenging capacity in mice alters host sensitivity to tumor necrosis factor toxicity but does not interfere with its antitumor efficacy
Q36286117Measuring tissue-based biomarkers by immunochromatography coupled with reverse-phase lysate microarray
Q70502480Mechanism of action of Cyclosporin A: inhibition of lymphokine secretion studied with antigen-stimulated T cell hybridomas
Q37930429Mechanisms of immunologic antitumor therapy: lessons from the laboratory and clinical applications
Q39671316Mechanistic aspects of successful immunotherapy of established pulmonary metastases by the systemic administration of high-dose recombinant interleukin-2.
Q41483867Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes
Q46577867Melanoma-associated B cells are distinct from peripheral blood-derived B cells, and may serve as a source of tumor-targeting antibodies
Q36366680Melanoma-specific CD4+ T cells recognize nonmutated HLA-DR-restricted tyrosinase epitopes
Q64990433Melanoma: Why is sentinel lymph node biopsy 'standard of care' for melanoma?
Q36430680Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy
Q61124550Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients
Q45048055Metabolic and renal effects of interleukin-2 immunotherapy for metastatic cancer.
Q37528784Metastasectomy Following Immunotherapy with Adoptive Cell Transfer for Patients with Advanced Melanoma.
Q93817055Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8 T cells via TLR4 signaling
Q35901034Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling.
Q34823783Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy
Q36127769Minimally invasive liver resection to obtain tumor-infiltrating lymphocytes for adoptive cell therapy in patients with metastatic melanoma
Q30621114Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
Q36908551Mobilization of dendritic cell precursors in patients with cancer by flt3 ligand allows the generation of higher yields of cultured dendritic cells
Q50925934Modulating the differentiation status of ex vivo-cultured anti-tumor T cells using cytokine cocktails.
Q34936175Modulation by IL-2 of CD70 and CD27 expression on CD8+ T cells: importance for the therapeutic effectiveness of cell transfer immunotherapy
Q70404768Modulation of murine tumor major histocompatibility antigens by cytokines in vivo and in vitro
Q36696205Multiple HLA class II-restricted melanocyte differentiation antigens are recognized by tumor-infiltrating lymphocytes from a patient with melanoma
Q34139613Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells.
Q47872727Murine Autoantibodies to a Cryptic Membrane Antigen: Possible Explanation for Neuraminidase-Induced Increase in Cell Immunogenicity2
Q46075479Murine lymphokine-activated killer (LAK) cells: phenotypic characterization of the precursor and effector cells
Q34729631Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.
Q35382936Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma
Q34682013Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma
Q37385138Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma
Q36029045Mutational inactivation of STAG2 causes aneuploidy in human cancer
Q34388520Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes
Q55056515Myeloid cells obtained from the blood but not from the tumor can suppress T-cell proliferation in patients with melanoma.
Q39641278NIH conference. New approaches to the immunotherapy of cancer using interleukin-2.
Q64958969NY-ESO-1 expression in synovial sarcoma and other mesenchymal tumors: significance for NY-ESO-1-based targeted therapy and differential diagnosis.
Q64898281NY-ESO-1 may be a potential target for lung cancer immunotherapy.
Q91328734Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers
Q35996395New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer
Q41002229No Initial Therapy for Stage III and IV Non-Hodgkin's Lymphomas of Favorable Histologic Types
Q56899941No correlation between clinical response to CTLA-4 blockade and presence of NY-ESO-1 antibody in patients with metastatic melanoma
Q54113062Non-Hodgkin's lymphomas. 3. Preliminary results of radiotherapy and a proposal for new clinical trials.
Q54576741Non-Hodgkin's lymphomas. IV. Clinicopathologic correlation in 405 cases.
Q44971100Non-Hodgkin's lymphomas.V. Results of radiotherapy
Q24648492Normal tissue depresses while tumor tissue enhances human T cell responses in vivo to a novel self/tumor melanoma antigen, OA1
Q35745453Novel CD4-Based Bispecific Chimeric Antigen Receptor Designed for Enhanced Anti-HIV Potency and Absence of HIV Entry Receptor Activity
Q34581746Novel somatic mutations in heterotrimeric G proteins in melanoma
Q34194434Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer
Q40983022Occurrence of Non-Hodgkin's Lymphoma after Therapy for Hodgkin's Disease
Q37275309Ocular and systemic autoimmunity after successful tumor-infiltrating lymphocyte immunotherapy for recurrent, metastatic melanoma
Q88407814Outcomes of Adoptive Cell Transfer With Tumor-infiltrating Lymphocytes for Metastatic Melanoma Patients With and Without Brain Metastases
Q38734913Overview of interleukin-2 as an immunotherapeutic agent
Q37726682PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors
Q33940443Pancreatic cancer: Hurdles in the engineering of CAR-based immunotherapies
Q36311681Paraneoplastic granulocytosis in metastatic melanoma
Q35063407Parathyroid hormone-related protein and hypercalcemia in patients with metastatic melanoma: case report and review
Q36344582Partial reduction of human FOXP3+ CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration
Q43500461Pathologic findings associated with interleukin-2-based immunotherapy for cancer: a postmortem study of 19 patients
Q41734221Patterns of relapse and response to retreatment in patients with metastatic melanoma or renal cell carcinoma who responded to interleukin-2-based immunotherapy
Q52491491Penetration of recombinant interleukin-2 across the blood-cerebrospinal fluid barrier.
Q35044333Persistence of CTL clones targeting melanocyte differentiation antigens was insufficient to mediate significant melanoma regression in humans
Q33210267Persistence of multiple tumor-specific T-cell clones is associated with complete tumor regression in a melanoma patient receiving adoptive cell transfer therapy
Q35568556Personalized cell transfer immunotherapy for B-cell malignancies and solid cancers
Q45896373Personalized immunotherapy for non-small cell lung cancer through identification of tumor-specific mutations by next generation sequencing and adoptive transfer of tumor infiltrating lymphocytes that recognize neoantigens
Q40865041Phase 1 study in patients with metastatic melanoma of immunization with dendritic cells presenting epitopes derived from the melanoma-associated antigens MART-1 and gp100.
Q56899396Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma
Q72718104Phase I study of human leukocyte interferon in patients with advanced cancer
Q33340438Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma
Q37107516Phenotype and function of T cells infiltrating visceral metastases from gastrointestinal cancers and melanoma: implications for adoptive cell transfer therapy
Q34648472Phenotypic and functional maturation of tumor antigen-reactive CD8+ T lymphocytes in patients undergoing multiple course peptide vaccination
Q44710348Phenotypic characterization of murine tumor-infiltrating T lymphocytes
Q92436994Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor-transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma
Q55154464Prednisone in MOPP chemotherapy for Hodgkin's disease
Q58714103Preinfusion polyfunctional anti-CD19 chimeric antigen receptor T cells are associated with clinical outcomes in NHL
Q36327106Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors
Q84600405Prevention of interleukin-2 withdrawal-induced apoptosis in lymphocytes retrovirally cotransduced with genes encoding an antitumor T-cell receptor and an antiapoptotic protein
Q34657676Primary human T lymphocytes engineered with a codon-optimized IL-15 gene resist cytokine withdrawal-induced apoptosis and persist long-term in the absence of exogenous cytokine
Q36327142Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines
Q50510003Production of recombinant MART-1 proteins and specific antiMART-1 polyclonal and monoclonal antibodies: use in the characterization of the human melanoma antigen MART-1.
Q70333123Prognostic factors in pathologic stage III Hodgkin's disease
Q36286133Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade
Q42259606Prospective evaluation of doxorubicin-induced cardiomyopathy resulting from postsurgical adjuvant treatment of patients with soft tissue sarcomas
Q38792012Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients
Q36456711Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness.
Q42223110Prospective study of cardiomyopathy induced by adjuvant doxorubicin therapy in patients with soft-tissue sarcomas
Q34507561Prospects for gene-engineered T cell immunotherapy for solid cancers.
Q41619271Quality of life assessment of patients in extremity sarcoma clinical trials.
Q40964694Quantitation of T-cell receptor frequencies by competitive PCR: generation and evaluation of novel TCR subfamily and clone specific competitors
Q41174063RANTES secretion by gene-modified tumor cells results in loss of tumorigenicity in vivo: role of immune cell subpopulations
Q48251012RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells
Q37065838Randomized selection design trial evaluating CD8+-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma.
Q34536176Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer
Q36027584Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma
Q100758899Rapid Identification and Evaluation of Neoantigen-reactive T-Cell Receptors From Single Cells
Q34519488Rapid production of clinical-grade gammaretroviral vectors in expanded surface roller bottles using a "modified" step-filtration process for clearance of packaging cells
Q37197945Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression
Q74463509Recognition of an antigenic peptide derived from tyrosinase-related protein-2 by CTL in the context of HLA-A31 and -A33
Q34657661Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR.
Q36321176Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma
Q90688967Recognition of human gastrointestinal cancer neoantigens by circulating PD-1+ lymphocytes
Q71804817Recognition of multiple epitopes in the human melanoma antigen gp100 by peripheral blood lymphocytes stimulated in vitro with synthetic peptides
Q72133139Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression
Q35535509Recognition of shared melanoma antigens by human tumor-infiltrating lymphocytes
Q73475194Recognition of shared melanoma antigens in association with major HLA-A alleles by tumor infiltrating T lymphocytes from 123 patients with melanoma
Q36752428Recognition of tyrosinase by tumor-infiltrating lymphocytes from a patient responding to immunotherapy
Q36484723Recombinant fowlpox viruses encoding the anchor-modified gp100 melanoma antigen can generate antitumor immune responses in patients with metastatic melanoma
Q69909342Recombinant interleukin 2 stimulates in vivo proliferation of adoptively transferred lymphokine-activated killer (LAK) cells
Q37112088Recurrent inactivating RASA2 mutations in melanoma
Q33418729Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer
Q67856845Relapse after response to interleukin-2-based immunotherapy: patterns of progression and response to retreatment
Q33927506Relationship of p53 overexpression on cancers and recognition by anti-p53 T cell receptor-transduced T cells
Q24540135Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells
Q35749986Replication-competent retroviruses in gene-modified T cells used in clinical trials: is it time to revise the testing requirements?
Q45790670Results of clinical trials with the administration of interleukin 2 and adoptive immunotherapy with activated cells in patients with cancer
Q43963971Retroviral transduction of human dendritic cells with a tumor-associated antigen gene.
Q36294795Risk of bowel perforation in patients receiving interleukin-2 after therapy with anti-CTLA 4 monoclonal antibody
Q68251706Risk of second cancers after treatment for Hodgkin's disease
Q37683228Routine Computer Tomography Imaging for the Detection of Recurrences in High-Risk Melanoma Patients
Q34582536Safety and efficacy of high-dose interleukin-2 therapy in patients with brain metastases
Q34307987Selection of CD8+PD-1+ lymphocytes in fresh human melanomas enriches for tumor-reactive T cells
Q45785742Selection of circulating PD-1+ lymphocytes from cancer patients enriches for tumor-reactive and mutation-specific lymphocytes.
Q34657700Selective elimination of human regulatory T lymphocytes in vitro with the recombinant immunotoxin LMB-2.
Q36327137Selective growth, in vitro and in vivo, of individual T cell clones from tumor-infiltrating lymphocytes obtained from patients with melanoma
Q54401823Separation and functional studies of the human lymphokine-activated killer cell.
Q68163347Separation and growth of human CD4+ and CD8+ tumor-infiltrating lymphocytes and peripheral blood mononuclear cells by direct positive panning on covalently attached monoclonal antibody-coated flasks
Q40641929Serum interleukin-6 levels in metastatic renal cell carcinoma before treatment with interleukin-2 correlates with paraneoplastic syndromes but not patient survival
Q54649386Shared human melanoma antigens. Recognition by tumor-infiltrating lymphocytes in HLA-A2.1-transfected melanomas.
Q35860034Simplified method of the growth of human tumor infiltrating lymphocytes in gas-permeable flasks to numbers needed for patient treatment
Q36938866Simultaneous targeting of tumor antigens and the tumor vasculature using T lymphocyte transfer synergize to induce regression of established tumors in mice.
Q36713758Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions
Q93104450Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy
Q37236693Single-pass, closed-system rapid expansion of lymphocyte cultures for adoptive cell therapy
Q56902369Skin reactions in a subset of patients with stage IV melanoma treated with anti-cytotoxic T-lymphocyte antigen 4 monoclonal antibody as a single agent
Q70580238Soft tissue sarcoma: functional outcome after wide local excision and radiation therapy
Q34051230Somatic mutation of GRIN2A in malignant melanoma results in loss of tumor suppressor activity via aberrant NMDAR complex formation
Q28397328Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin
Q55423983Specific increase in T cell potency via structure-based design of a T cell receptor for adoptive immunotherapy.
Q34383054Specific increase in potency via structure-based design of a TCR.
Q42619352Specific release of cytokines by lymphocytes infiltrating human melanomas in response to shared melanoma antigens.
Q67987672Specific release of granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-alpha, and IFN-gamma by human tumor-infiltrating lymphocytes after autologous tumor stimulation
Q37043492Stable, Nonviral Expression of Mutated Tumor Neoantigen-specific T-cell Receptors Using the Sleeping Beauty Transposon/Transposase System.
Q53809960Staging laparotomies in unselected previously untreated patients with non-Hodgkin's lymphomas
Q69594250Staging laparotomy and splenectomy in Hodgkin's disease: analysis of indications and patterns of involvement in 285 consecutive, unselected patients
Q40864307Status of activation of circulating vaccine-elicited CD8+ T cells
Q104281851Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer
Q40649080Stimulation of tumor-reactive T lymphocytes using mixtures of synthetic peptides derived from tumor-associated antigens with diverse MHC binding affinities
Q27680213Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity
Q44849269Studies of effects of recombinant human tumor necrosis factor on autochthonous tumor and transplanted normal tissue in mice.
Q69727000Studies on the anti-tumor efficacy of systemically administered recombinant tumor necrosis factor against several murine tumors in vivo
Q45893718Study and characterization of mutated antigen specific T cells isolated from fresh tumor and peripheral lymphocytes in cancer patients
Q42933679Successful treatment of melanoma brain metastases with adoptive cell therapy.
Q71596799Surgical Staging of Abdominal Involvement in Unselected Patients with Hodgkin's Disease
Q34954990Surgical management of melanoma brain metastases in patients treated with immunotherapy.
Q36327111Survival, persistence, and progressive differentiation of adoptively transferred tumor-reactive T cells associated with tumor regression
Q54254954Synergistic antitumor effects of combination immunotherapy with recombinant interleukin-2 and a recombinant hybrid alpha-interferon in the treatment of established murine hepatic metastases.
Q68094889Synergistic antitumor effects of immunotherapy with recombinant interleukin-2 and recombinant tumor necrosis factor-alpha
Q40824218Systemic administration of interleukin-2 in humans
Q70228761Systemic administration of recombinant human interleukin-2 in mice
Q48466552Systemic administration of recombinant interleukin 2 stimulates in vivo lymphoid cell proliferation in tissues
Q69376234Systemic induction of cells mediating antibody-dependent cellular cytotoxicity following administration of interleukin 2
Q46576941T cell receptor affinity and avidity defines antitumor response and autoimmunity in T cell immunotherapy
Q69381218T cell responses to Mls determinants are restricted by cross-reactive MHC determinants
Q33202641T cells associated with tumor regression recognize frameshifted products of the CDKN2A tumor suppressor gene locus and a mutated HLA class I gene product
Q40186710T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
Q34621730T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.
Q92592749T-Cell Receptor Gene Therapy for Human Papillomavirus-Associated Epithelial Cancers: A First-in-Human, Phase I/II Study
Q30832820T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer.
Q88938409T-cell Responses to TP53 "Hotspot" Mutations and Unique Neoantigens Expressed by Human Ovarian Cancers
Q36799229T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy
Q36449599T-cell receptor gene therapy of established tumors in a murine melanoma model
Q41452804T-cell receptor repertoire in tumor-infiltrating lymphocytes. Analysis of melanoma-specific long-term lines
Q42848657T-cell therapy against cancer mutations
Q36924688TGF-beta 1 attenuates the acquisition and expression of effector function by tumor antigen-specific human memory CD8 T cells
Q36057454TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients.
Q36154471Targeting of HPV-16+ Epithelial Cancer Cells by TCR Gene Engineered T Cells Directed against E6
Q68451405Technical aspects of lymphokine-activated killer cell production
Q45892658Tetramer based approach for efficient identification and isolation of neo-antigen specific CD8 T cells from peripheral blood (PBL) of patients with metastatic cancers
Q33577629The GYMSSA trial: a prospective randomized trial comparing gastrectomy, metastasectomy plus systemic therapy versus systemic therapy alone
Q43445412The Persistence of Human Peripheral Lymphocytes, Tumor Infiltrating Lymphocytes, and Colon Adenocarcinomas in Immunodeficient Mice
Q36923906The Waardenburg syndrome type 4 gene, SOX10, is a novel tumor-associated antigen identified in a patient with a dramatic response to immunotherapy
Q69892964The anti-tumor efficacy of lymphokine-activated killer cells and recombinant interleukin 2 in vivo
Q69880385The anti-tumor efficacy of lymphokine-activated killer cells and recombinant interleukin 2 in vivo: direct correlation between reduction of established metastases and cytolytic activity of lymphokine-activated killer cells
Q69934702The concept, evolution and preliminary results of the current Stanford clinical trials for Hodgkin's disease
Q41279485The current status and future applications of interleukin 2- and adoptive immunotherapy in cancer treatment
Q45873266The development of gene therapy for the treatment of cancer
Q69490209The effect of various cytokines on the in vitro induction of antibody-dependent cellular cytotoxicity in murine cells. Enhancement of IL-2-induced antibody-dependent cellular cytotoxicity activity by IL-1 and tumor necrosis factor-alpha
Q45242251The evolution and summary results of the Stanford randomized clinical trials of the management of Hodgkin's disease: 1962-1984.
Q70984165The fate of interleukin-2 after in vivo administration
Q33490318The hematologic toxicity of interleukin-2 in patients with metastatic melanoma and renal cell carcinoma
Q72079058The in vivo distribution of autologous human and murine lymphoid cells grown in T cell growth factor (TCGF): implications for the adoptive immunotherapy of tumors
Q36867815The intronic region of an incompletely spliced gp100 gene transcript encodes an epitope recognized by melanoma-reactive tumor-infiltrating lymphocytes
Q70281536The management of stage I--II Hodgkin's disease with irradiation alone or combined modality therapy: the Stanford experience
Q70817025The natural history of initially untreated low-grade non-Hodgkin's lymphomas
Q43430836The potential benefits of therapeutic splenectomy for patients with Hodgkin's disease and non-Hodgkin's lymphomas
Q33987699The shedding of CD62L (L-selectin) regulates the acquisition of lytic activity in human tumor reactive T lymphocytes
Q50940546The stoichiometric production of IL-2 and IFN-γ mRNA defines memory T cells that can self-renew after adoptive transfer in humans.
Q71002948The systemic administration of purified interleukin 2 enhances the ability of sensitized murine lymphocytes to cure a disseminated syngeneic lymphoma
Q33486169The treatment of advanced stage favorable histology non-Hodgkin's lymphoma: a preliminary report of a randomized trial comparing single agent chemotherapy, combination chemotherapy, and whole body irradiation.
Q71009949The treatment of malignant histiocytosis
Q72313142The use of interleukin-6 to generate tumor-infiltrating lymphocytes with enhanced in vivo antitumor activity
Q47807208The use of melanosomal proteins in the immunotherapy of melanoma
Q36291063The value of sequential bone marrow biopsy and laparotomy and splenectomy in a series of 127 consecutive untreated patients with non-Hodgkin's lymphoma
Q44784874Third-line chemotherapy for resistant Hodgkin's disease with lomustine, etoposide, and methotrexate.
Q37768258Thoracic metastasectomy for adoptive immunotherapy of melanoma: a single-institution experience
Q33413012Thrombotic microangiopathy in metastatic melanoma patients treated with adoptive cell therapy and total body irradiation
Q71189347Thyroid dysfunction in 281 patients with metastatic melanoma or renal carcinoma treated with interleukin-2 alone
Q36253608Toll-like receptors in tumor immunotherapy
Q45754160Toward cell transfer immunotherapy against patient-specific mutations in gastrointestinal cancers
Q69872338Toxicity of recombinant human interleukin-2 in rats following intravenous infusion
Q34795354Transduction of an HLA-DP4-restricted NY-ESO-1-specific TCR into primary human CD4+ lymphocytes
Q34669675Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions
Q36908563Transition of late-stage effector T cells to CD27+ CD28+ tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy
Q35353365Treating cancer with genetically engineered T cells
Q45870820Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II-Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3.
Q39487510Treatment of advanced Hodgkin's disease with B-CAVE following MOPP failure
Q39490709Treatment of advanced Hodgkin's disease with adriamycin, bleomycin, vinblastine, and imidazole carboxamide (ABVD) after failure of MOPP therapy
Q67478803Treatment of advanced non-Hodgkin's lymphomas with favorable histologies: preliminary results of a prospective trial
Q37129949Treatment of metastatic melanoma using interleukin-2 alone or in conjunction with vaccines
Q33440852Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: a single-centre, two-stage, single-arm, phase 2 study
Q69017552Treatment of refractory non-Hodgkin's lymphomas of unfavorable histology with teniposide, cytarabine, and cisplatin
Q33503368Trends in the safety of high dose bolus interleukin-2 administration in patients with metastatic cancer
Q39655893Tumor Infiltrating Lymphocyte Therapy for Metastatic Melanoma: Analysis of Tumors Resected for TIL
Q34080914Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
Q45287769Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8+ T cells in patients with melanoma
Q36371632Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.
Q34657668Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: a phase I/II study
Q39647119Tumor- and Neoantigen-Reactive T-cell Receptors Can Be Identified Based on Their Frequency in Fresh Tumor
Q91009823Tumor-infiltrating human CD4+ regulatory T cells display a distinct TCR repertoire and exhibit tumor and neoantigen reactivity
Q72884570Tumor-infiltrating lymphocytes derived from select B-cell lymphomas secrete granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha in response to autologous tumor stimulation
Q73373378Tumor-infiltrating lymphocytes from human ovarian cancer patients recognize autologous tumor in an MHC class II-restricted fashion
Q35613148Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma
Q37590119Tumor-reactive CD8+ T cells in metastatic gastrointestinal cancer refractory to chemotherapy.
Q84107453Tumor-specific CD4+ melanoma tumor-infiltrating lymphocytes
Q34109953Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts
Q69738303Tumor-specific cytolysis by lymphocytes infiltrating human melanomas
Q40898515Tumorigenicity and immunogenicity of murine tumor cells expressing an MHC class II molecule with a covalently bound antigenic peptide
Q92523541Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers
Q43695332Unique murine tumor-associated antigens identified by tumor infiltrating lymphocytes
Q45892768Unique neoantigens expressed by melanomas and common epithelial cancers presented by multiple HLA alleles can be efficiently identified utilizing peptide prediction algorithms
Q45871736Upregulation of tumor necrosis factor-alpha production by retrovirally transduced human tumor-infiltrating lymphocytes using trans-retinoic acid
Q45892880Use of CD137 up-regulation to identify T cell receptors specifically reactive with mutated tumor associated antigens from tumor infiltrating lymphocytes
Q36905613Use of HLA peptidomics and whole exome sequencing to identify human immunogenic neo-antigens.
Q71608052Use of interleukin-7, interleukin-2, and interferon-gamma to propagate CD4+ T cells in culture with maintained antigen specificity
Q43702722Use of recombinant poxviruses to stimulate anti-melanoma T cell reactivity
Q44712586Use of soluble recombinant TNF receptor to improve detection of TNF secretion in cultures of tumor infiltrating lymphocytes
Q34703600Use of standard criteria for assessment of cancer vaccines.
Q34082215Use of the piggyBac transposon to create stable packaging cell lines for the production of clinical-grade self-inactivating γ-retroviral vectors
Q68100559Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report
Q36365832Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen
Q71659964Vitiligo in patients with melanoma: normal tissue antigens can be targets for cancer immunotherapy
Q37104104Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma
Q34188859gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
Q100443984mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer

Q1324940Keio Medical Science PrizewinnerP1346
Q63865665Steven A. Rosenbergdifferent fromP1889

The articles in Wikimedia projects and languages

Arabic (ar / Q13955)ستيفن روزنبرغwikipedia
Egyptian Arabic (arz / Q29919)ستيفن روزنبرجwikipedia
      Steven A. Rosenbergwikipedia
      Steven Rosenbergwikipedia
Persian (fa / Q9168)استیون روزنبرگwikipedia
      סטיבן רוזנברגwikipedia
      Steven Rosenbergwikipedia
      スティーヴン・ローゼンバーグwikipedia
      Steven Rosenbergwikipedia
      Розенберг, Стивенwikipedia

Search more.