An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors.

scientific article published on 28 October 2017

An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YMTHE.2017.10.018
P932PMC publication ID5835023
P698PubMed publication ID29174843

P50authorSteven RosenbergQ2347448
Yong-Chen LuQ42199992
P2093author name stringSatyajit Ray
Paul F Robbins
Peter C Fitzgerald
Yong F Li
Zhili Zheng
Jared J Gartner
Todd D Prickett
Eric Tran
Valery Bliskovsky
Zulmarie Franco
P2860cites workHigh-throughput pairing of T cell receptor α and β sequencesQ85935018
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Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsQ30621114
T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer.Q30832820
Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions.Q33851742
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Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.Q36286122
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Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patientsQ36551911
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Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytesQ37113080
Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expressionQ37197945
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Incorporation of transmembrane hydrophobic mutations in the TCR enhance its surface expression and T cell functional avidity.Q39356556
Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cellsQ41916556
A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 daysQ42244370
Tumor and Microenvironment Evolution during Immunotherapy with NivolumabQ45070125
Lethal graft-versus-host disease in mouse models of T cell receptor gene therapyQ45858516
Mechanisms regulating T-cell infiltration and activity in solid tumorsQ50089395
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer.Q50906889
Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancerQ57152489
Expression of two T cell receptor alpha chains: dual receptor T cellsQ61268447
4-1BB ligand-mediated costimulation of human T cells induces CD4 and CD8 T cell expansion, cytokine production, and the development of cytolytic effector functionQ78057869
P433issue2
P921main subjectRNA sequencingQ2542347
single-cell RNA-seqQ18409577
P304page(s)379-389
P577publication date2017-10-28
P1433published inMolecular TherapyQ15762400
P1476titleAn Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors
P478volume26

Reverse relations

cites work (P2860)
Q92963159Best practices for bioinformatic characterization of neoantigens for clinical utility
Q93167902CAR T cell therapy: newer approaches to counter resistance and cost
Q90576547Developing neoantigen-targeted T cell-based treatments for solid tumors
Q55011828Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells.
Q57029270Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy
Q64884539Functional genomics: paving the way for more successful cancer immunotherapy.
Q92509274Identification of drug-specific public TCR driving severe cutaneous adverse reactions
Q89456690Next-generation sequencing technologies accelerate advances in T-cell therapy for cancer
Q93104450Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy

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