Selection of CD8+PD-1+ lymphocytes in fresh human melanomas enriches for tumor-reactive T cells

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Selection of CD8+PD-1+ lymphocytes in fresh human melanomas enriches for tumor-reactive T cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1097/CJI.0B013E3181FAD2B0
P932PMC publication ID2980947
P698PubMed publication ID20948441

P50authorSteven RosenbergQ2347448
Ken-Ichi HanadaQ71142559
P2093author name stringJames C Yang
John R Wunderlich
Takashi Inozume
Qiong J Wang
Mojgan Ahmadzadeh
P2860cites workGM-CSF/IL-3/IL-5 receptor common beta chain (CD131) expression as a biomarker of antigen-stimulated CD8+ T cellsQ36580172
Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunityQ36693023
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Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinomaQ39888328
Generating renal cancer-reactive T cells using dendritic cells (DCs) to present autologous tumor.Q40362192
Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer.Q54287306
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell deathQ24293504
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanismsQ24534904
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Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activationQ24675931
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancerQ24685406
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasionQ28131654
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptorQ28144319
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient miceQ28201627
Restoring function in exhausted CD8 T cells during chronic viral infectionQ28289222
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progressionQ29618956
Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impairedQ34080914
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunctionQ34570127
Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapyQ34823783
Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificitiesQ35850673
Adoptive cell therapy for the treatment of patients with metastatic melanomaQ36283034
Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patientsQ36551911
P433issue9
P304page(s)956-964
P577publication date2010-11-01
P1433published inJournal of ImmunotherapyQ15763946
P1476titleSelection of CD8+PD-1+ lymphocytes in fresh human melanomas enriches for tumor-reactive T cells
P478volume33