Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy

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Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1097/CJI.0B013E31818403D5
P932PMC publication ID2614999
P698PubMed publication ID18779745

P50authorSteven RosenbergQ2347448
P2093author name stringPaul F Robbins
Khoi Q Tran
John R Wunderlich
Mark E Dudley
Michelle M Langhan
Juhua Zhou
Thomas E Shelton
Katherine H Durflinger
P2860cites workTransition of late-stage effector T cells to CD27+ CD28+ tumor-reactive effector memory T cells in humans after adoptive cell transfer therapyQ36908563
Phase I study of adoptive T-cell therapy using antigen-specific CD8+ T cells for the treatment of patients with metastatic melanoma.Q40465923
Biology and adoptive cell therapy of Epstein-Barr virus-associated lymphoproliferative disorders in recipients of marrow allografts.Q41561745
The use of anti-CD3 and anti-CD28 monoclonal antibodies to clone and expand human antigen-specific T cellsQ41736991
Characterization of Lymphocytes Infiltrating Human Breast Cancer, Specific Immune Reactivity Detected by Measuring Cytokine SecretionQ41766668
Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell HelpQ42642562
Treatment of nasopharyngeal carcinoma with Epstein-Barr virus--specific T lymphocytesQ45551744
Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients.Q45754081
Cancer/testis antigen expression and specific cytotoxic T lymphocyte responses in non small cell lung cancer.Q54574332
Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary reportQ68100559
Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2Q72052802
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cellsQ24530100
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanomaQ24548019
Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimensQ24644442
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A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanomaQ33342339
Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cellsQ33831940
Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell MemoryQ34190038
Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy.Q34314036
Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cellsQ34415738
High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival updateQ34507305
Allogeneic cytotoxic T-cell therapy for EBV-positive posttransplantation lymphoproliferative disease: results of a phase 2 multicenter clinical trialQ34623991
Modulation by IL-2 of CD70 and CD27 expression on CD8+ T cells: importance for the therapeutic effectiveness of cell transfer immunotherapyQ34936175
Persistence of tumor infiltrating lymphocytes in adoptive immunotherapy correlates with telomere length.Q36294809
Survival, persistence, and progressive differentiation of adoptively transferred tumor-reactive T cells associated with tumor regressionQ36327111
Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patientsQ36551911
Chemotherapy for metastatic melanoma: time for a change?Q36698282
P433issue8
P304page(s)742-751
P577publication date2008-10-01
P1433published inJournal of ImmunotherapyQ15763946
P1476titleMinimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy
P478volume31

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