Loss of phosphatase and tensin homolog expression correlates with clinicopathological features of non-small cell lung cancer patients and its impact on survival: A systematic review and meta-analysis

scientific article

Loss of phosphatase and tensin homolog expression correlates with clinicopathological features of non-small cell lung cancer patients and its impact on survival: A systematic review and meta-analysis is …
instance of (P31):
meta-analysisQ815382
scholarly articleQ13442814

External links are
P356DOI10.1111/1759-7714.12425
P932PMC publication ID5415467
P698PubMed publication ID28263037

P2093author name stringJian Li
Feng Lin
Lunxu Liu
Yongsheng Zhao
Renyan Zheng
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Operating characteristics of a rank correlation test for publication biasQ27860653
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statementQ27860749
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
Practical methods for incorporating summary time-to-event data into meta-analysisQ28131754
PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathwayQ28139300
Loss of PTEN facilitates HIF-1-mediated gene expressionQ28145476
PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer modelQ28202775
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancersQ28306997
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTENQ28513537
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathwayQ28588309
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathwayQ33599964
A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.Q33929512
Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX studyQ33969308
PTEN and Ki67 expression is associated with clinicopathologic features of non-small cell lung cancerQ34606601
Prognostic value of the expression of phosphatase and tensin homolog and CD44 in elderly patients with refractory acute myeloid leukemiaQ35803001
Prognostic Significance of mTOR and PTEN in Patients with Esophageal Squamous Cell CarcinomaQ36013408
Combinations of laminin 5 with PTEN, p-EGFR and p-Akt define a group of distinct molecular subsets indicative of poor prognosis in patients with non-small cell lung cancerQ36285667
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesisQ36384467
High-expression of DJ-1 and loss of PTEN associated with tumor metastasis and correlated with poor prognosis of gastric carcinomaQ37249335
PTEN: a new guardian of the genome.Q37270432
Worldwide Overview of the Current Status of Lung Cancer Diagnosis and TreatmentQ38063540
PTEN.Q38218236
Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesisQ40679766
Concurrent deletion of 16q23 and PTEN is an independent prognostic feature in prostate cancerQ40903462
Loss of PTEN expression is associated with aggressive behavior and poor prognosis in Middle Eastern triple-negative breast cancer.Q40931689
High levels of phosphatase and tensin homolog expression predict favorable prognosis in patients with non-small cell lung cancerQ41593058
Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer.Q43222717
Increased tissue factor expression is associated with reduced survival in non-small cell lung cancer and with mutations of TP53 and PTEN.Q43297266
Prognostic value of matrix metalloproteinase-7 expression in patients with non-small cell lung cancerQ43578829
PTEN and PIK3CA expression is associated with prolonged survival after gefitinib treatment in EGFR-mutated lung cancer patients.Q44846498
Phosphorylated Akt overexpression and loss of PTEN expression in non-small cell lung cancer confers poor prognosisQ47680928
Alteration of the E-cadherin/β-catenin complex predicts poor response to epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) treatmentQ51072877
Expression of FAK and PTEN in bronchioloalveolar carcinoma and lung adenocarcinomaQ51799708
Immunohistochemical characterization of the mTOR pathway in stage-I non-small-cell lung carcinomaQ53220076
Histologic-type specific role of cell cycle regulators in non-small cell lung carcinomaQ53376865
Expression and clinical evidence of miR-494 and PTEN in non-small cell lung cancerQ53550499
Loss of phosphatase and tensin homolog protein expression is an independent poor prognostic marker in lung adenocarcinoma.Q54483370
Expression patterns of USP22 and potential targets BMI-1, PTEN, p-AKT in non-small-cell lung cancerQ54502976
Expression of the Mammalian Target of Rapamycin Pathway Markers in Lung Adenocarcinoma and Squamous Cell CarcinomaQ54533454
mTOR and PTEN expression in non-small cell lung cancer: analysis by real-time fluorescence quantitative polymerase chain reaction and immunohistochemistryQ54546623
PTEN and phosphorylated AKT expression and prognosis in early- and late-stage non-small cell lung cancerQ79889036
Expression of PTEN and FHIT is involved in regulating the balance between apoptosis and proliferation in lung carcinomasQ79911245
The prognostic value of osteopontin expression in non-small cell lung cancer: a meta-analysisQ87851600
P433issue3
P304page(s)203-213
P577publication date2017-03-06
P1433published inThoracic CancerQ26842004
P1476titleLoss of phosphatase and tensin homolog expression correlates with clinicopathological features of non-small cell lung cancer patients and its impact on survival: A systematic review and meta-analysis
P478volume8

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cites work (P2860)
Q58122535Identification of Candidate Biomarkers Correlated With the Pathogenesis and Prognosis of Non-small Cell Lung Cancer via Integrated Bioinformatics Analysis
Q58788315Pectolinarigenin inhibits non‑small cell lung cancer progression by regulating the PTEN/PI3K/AKT signaling pathway
Q47620321The Smad4/PTEN Expression Pattern Predicts Clinical Outcomes in Colorectal Adenocarcinoma

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