| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Richard F Loeser | Q88623051 |
| P2093 | author name string | A Shane Anderson | |
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| Association between age and knee structural change: a cross sectional MRI based study. | Q35555369 | ||
| Aging or osteoarthritis: which is the problem? | Q35578043 | ||
| Cell death in cartilage. | Q35617281 | ||
| Symptoms and radiographic osteoarthritis: not as discordant as they are made out to be? | Q35638385 | ||
| A framework for the in vivo pathomechanics of osteoarthritis at the knee | Q35750609 | ||
| Increasing age at symptom onset is associated with worse radiological damage at presentation in patients with early inflammatory polyarthritis | Q35759949 | ||
| The importance of subchondral bone in the progression of osteoarthritis | Q35767161 | ||
| Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration | Q35768757 | ||
| Mechanisms of cellular senescence in human and mouse cells. | Q35770883 | ||
| Apoptosis in osteoarthritis | Q35839791 | ||
| Mitochondrial redox control of matrix metalloproteinases | Q35860310 | ||
| Osteoarthritis: epidemiology | Q36399049 | ||
| Calcium crystal deposition and osteoarthritis | Q36485431 | ||
| Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis. | Q36725162 | ||
| Systematic review of the prevalence of radiographic primary hip osteoarthritis | Q37082883 | ||
| Defining incident radiographic hip osteoarthritis for epidemiologic studies in women | Q37183520 | ||
| Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized. | Q37207072 | ||
| Meniscal tear in knees without surgery and the development of radiographic osteoarthritis among middle-aged and elderly persons: The Multicenter Osteoarthritis Study | Q37378387 | ||
| An update on the epidemiology of calcium pyrophosphate dihydrate crystal deposition disease | Q37461880 | ||
| Age-related changes in the composition, the molecular stoichiometry and the stability of proteoglycan aggregates extracted from human articular cartilage | Q38361031 | ||
| Clinical aspects of calcium pyrophosphate dihydrate crystal deposition | Q39270878 | ||
| Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association | Q39513001 | ||
| Prevalence of symptomatic knee, hand, and hip osteoarthritis in Greece. The ESORDIG study | Q39777234 | ||
| Prevalence of radiographic knee osteoarthritis and its association with knee pain in the elderly of Japanese population-based cohorts: the ROAD study | Q39883407 | ||
| Chondrocyte apoptosis in development, aging and disease | Q40847480 | ||
| Chondrocyte apoptosis increases with age in the articular cartilage of adult animals | Q41047463 | ||
| Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage | Q42989445 | ||
| Telomere erosion and senescence in human articular cartilage chondrocytes. | Q43562778 | ||
| The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study | Q43781035 | ||
| Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis | Q43873300 | ||
| Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1. | Q44159746 | ||
| Induction of advanced glycation end products and alterations of the tensile properties of articular cartilage | Q44250392 | ||
| Synovial fluid features and their relations to osteoarthritis severity: new findings from sequential studies | Q44264962 | ||
| Increased oxidative stress with aging reduces chondrocyte survival: correlation with intracellular glutathione levels | Q44692192 | ||
| The effect of body weight on progression of knee osteoarthritis is dependent on alignment | Q44739854 | ||
| Accumulation of advanced glycation end products as a molecular mechanism for aging as a risk factor in osteoarthritis | Q44839345 | ||
| The cell density of human femoral head cartilage. | Q45153923 | ||
| Prevalence of knee symptoms and radiographic and symptomatic knee osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project | Q46142236 | ||
| The risk of osteoarthritis with running and aging: a 5-year longitudinal study. | Q46254839 | ||
| Identification of mesenchymal progenitor cells in normal and osteoarthritic human articular cartilage | Q47596861 | ||
| Bone marrow edema and its relation to progression of knee osteoarthritis. | Q52009435 | ||
| The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: the Framingham Study. | Q52868496 | ||
| Catabolic stress induces features of chondrocyte senescence through overexpression of caveolin 1: possible involvement of caveolin 1-induced down-regulation of articular chondrocytes in the pathogenesis of osteoarthritis. | Q54615793 | ||
| Erosive osteoarthritis | Q56288813 | ||
| Cruciate ligament integrity in osteoarthritis of the knee | Q57244865 | ||
| Osteoarthritis: Is it a disease of cartilage or of bone? | Q57244874 | ||
| Prevalence of Symptomatic Hand Osteoarthritis and Its Impact on Functional Status among the Elderly: The Framingham Study | Q57244884 | ||
| The Role of Knee Alignment in Disease Progression and Functional Decline in Knee Osteoarthritis | Q57244900 | ||
| The incidence and natural history of knee osteoarthritis in the elderly, the framingham osteoarthritis study | Q57244926 | ||
| Incidence of symptomatic hand, hip, and knee osteoarthritis among patients in a health maintenance organization | Q57244927 | ||
| Association of Bone Marrow Lesions with Knee Structures and Risk Factors for Bone Marrow Lesions in the Knees of Clinically Healthy, Community-Based Adults | Q57265745 | ||
| Growth factor responsiveness of human articular chondrocytes in aging and development | Q58913113 | ||
| Replicative aging of human articular chondrocytes during ex vivo expansion | Q59348652 | ||
| Intracellular determinants of cell aging. | Q64993190 | ||
| Aging, long-distance running, and the development of musculoskeletal disability. A controlled study | Q68948147 | ||
| Human osteoarthritic chondrocytes possess an increased number of insulin-like growth factor 1 binding sites but are unresponsive to its stimulation. Possible role of IGF-1-binding proteins | Q71613980 | ||
| Age-related changes in cartilage proteoglycans: quantitative electron microscopic studies | Q72699504 | ||
| Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease | Q73028069 | ||
| Age-related changes in human anterior cruciate ligament (ACL) collagen fibrils | Q73467830 | ||
| Detection of superoxide and NADPH oxidase in porcine articular chondrocytes | Q73695200 | ||
| Articular chondrocytes from aging rats respond poorly to insulin-like growth factor-1: an altered signaling pathway | Q73897652 | ||
| Age-related decline in chondrocyte response to insulin-like growth factor-I: the role of growth factor binding proteins | Q73900827 | ||
| Evidence linking chondrocyte lipid peroxidation to cartilage matrix protein degradation. Possible role in cartilage aging and the pathogenesis of osteoarthritis | Q73924378 | ||
| Autocrine stimulation by insulin-like growth factor 1 and insulin-like growth factor 2 mediates chondrocyte survival in vitro | Q74023967 | ||
| Aggrecan turnover in human articular cartilage: use of aspartic acid racemization as a marker of molecular age | Q74186098 | ||
| Effect of collagen turnover on the accumulation of advanced glycation end products | Q74281392 | ||
| Joint injury in young adults and risk for subsequent knee and hip osteoarthritis | Q74295933 | ||
| Modifiers of change in physical functioning in older adults with knee pain: the Observational Arthritis Study in Seniors (OASIS) | Q74361358 | ||
| Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13 | Q74714921 | ||
| P433 | issue | 1 | |
| P921 | main subject | osteoarthritis | Q62736 |
| P304 | page(s) | 15-26 | |
| P577 | publication date | 2010-02-01 | |
| P1433 | published in | Best Practice & Research: Clinical Rheumatology | Q4896784 |
| P1476 | title | Why is osteoarthritis an age-related disease? | |
| P478 | volume | 24 |
| Q99605408 | 3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants |
| Q47251009 | A Bayesian Approach to Age-at-Death Estimation from Osteoarthritis of the Shoulder in Modern North Americans |
| Q58920360 | A Study of Changes in Morphology of Osteoarthritic Articular Cartilage Using Computerized Image Analysis |
| Q57550118 | A theory of planned behavior-based intervention to improve quality of life in patients with knee/hip osteoarthritis: a randomized controlled trial |
| Q47237217 | Accessibility of online self-management support websites for people with osteoarthritis: A text content analysis |
| Q64258524 | Activation of mTORC1 in subchondral bone preosteoblasts promotes osteoarthritis by stimulating bone sclerosis and secretion of CXCL12 |
| Q49996841 | Activation of the cannabinoid receptor 1 by ACEA suppresses senescence in human primary chondrocytes through sirt1 activation |
| Q46830048 | Advanced glycation end products-induced chondrocyte apoptosis through mitochondrial dysfunction in cultured rabbit chondrocyte |
| Q40834670 | Age-independent effects of hyaluronan amide derivative and growth hormone on human osteoarthritic chondrocytes |
| Q38235496 | Ageing and osteoarthritis: a circadian rhythm connection. |
| Q42319037 | Aging Promotes Sirtuin 3-Dependent Cartilage Superoxide Dismutase 2 Acetylation and Osteoarthritis |
| Q33976707 | Aging and oxidative stress reduce the response of human articular chondrocytes to insulin-like growth factor 1 and osteogenic protein 1. |
| Q34199776 | Aging, cellular senescence, and cancer |
| Q36242690 | Aging-related inflammation in osteoarthritis |
| Q36722913 | Ankle rotation changes and its influences in knee osteoarthritis |
| Q35634979 | Applications of proteomics to osteoarthritis, a musculoskeletal disease characterized by aging |
| Q40708305 | Are daily physical activities risk factors for knee osteoarthritis? |
| Q99609481 | Arthritis and the role of endogenous glucocorticoids |
| Q92627063 | Arthroscopic Hip Joint Assessment can Impact the Indications for PAO Surgery |
| Q98205102 | Aspiration-assisted bioprinting of the osteochondral interface |
| Q40450881 | Assessment of cartilage contact pressure and loading in the hip joint during split posture. |
| Q30941103 | Association between serum vitamin D status and health-related quality of life (HRQOL) in an older Korean population with radiographic knee osteoarthritis: data from the Korean national health and nutrition examination survey (2010-2011) |
| Q34225355 | Biological aspects of early osteoarthritis |
| Q35764129 | Biomechanical considerations in the pathogenesis of osteoarthritis of the knee |
| Q38335744 | Cardiovascular disease and osteoarthritis: common pathways and patient outcomes |
| Q47375322 | Cartilage oligomeric protein, matrix metalloproteinase-3, and Coll2-1 as serum biomarkers in knee osteoarthritis: a cross-sectional study. |
| Q36263521 | Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway. |
| Q38214929 | Cell senescence: role in aging and age-related diseases |
| Q36903367 | Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis |
| Q35783681 | Changes in Chondrogenic Progenitor Populations Associated with Aging and Osteoarthritis |
| Q94602078 | Chronic pain and use of analgesics in the elderly: a nationwide population-based study |
| Q112744418 | Circular RNA mmu_circ_0001598 Contributes to IL-1β-Induced Osteoarthritis Progression by Regulating miR-127-3p |
| Q64082701 | Clinical characteristics and disability in patients with knee osteoarthritis: real world experience from Bulgaria |
| Q51317607 | Clinical profile of Filipino patients with osteoarthritis seen at two arthritis clinics. |
| Q38684546 | Comparative Pathology of Aging Great Apes: Bonobos, Chimpanzees, Gorillas, and Orangutans |
| Q41636832 | Development of a Tool to Predict Outcome of Autologous Chondrocyte Implantation. |
| Q37404463 | Development of physical disability in older adults |
| Q36485716 | Diseases concomitant with asthma in middle-aged and elderly subjects in Korea: a population-based study |
| Q47737748 | Distribution of osteoarthritis in a Norwegian population-based cohort: associations to risk factor profiles and health-related quality of life. |
| Q93128806 | Do psychological factors or radiographic severity play a role in the age of onset in symptomatic developmental dysplasia of hip and femoroacetabular impingement syndrome? |
| Q36426155 | ECM production of primary human and bovine chondrocytes in hybrid PEG hydrogels containing type I collagen and hyaluronic acid |
| Q92702792 | Effect of Aerobic Physical Activity on Health-Related Quality of Life in Middle Aged Women with Osteoarthritis: Korea National Health and Nutrition Examination Survey (2016-2017) |
| Q50271141 | Effect of advanced oxidation protein products on articular cartilage and synovium in a rabbit osteoarthritis model. |
| Q58863988 | Effect of aerobic training on plasma cytokines and soluble receptors in elderly women with knee osteoarthritis, in response to acute exercise |
| Q37652063 | Effect of aging on stem cells. |
| Q39011053 | Estimating the Burden of Osteoarthritis to Plan for the Future |
| Q61447879 | Evaluation of the prevalence of musculoskeletal symptoms, presumptive diagnosis, medical care use, and sick leave among female school meal service workers |
| Q34255848 | Evidence of changes to skeletal muscle contractile properties during the initiation of disease in the ageing guinea pig model of osteoarthritis |
| Q37194398 | Exercise for people with hip or knee osteoarthritis: a comparison of land-based and aquatic interventions |
| Q92970208 | Facet joint degeneration in adolescent idiopathic scoliosis |
| Q38827962 | Five common clinical presentations in the elderly: An anatomical review |
| Q61800197 | Frailty Questionnaire Is Not a Strong Prognostic Factor for Functional Outcomes in Hip or Knee Arthroplasty Patients |
| Q89422616 | Functionality in Middle-Aged and Older Overweight and Obese Individuals with Knee Osteoarthritis |
| Q37666649 | Future directions in painful knee osteoarthritis: harnessing complexity in a heterogeneous population |
| Q38996102 | Health Care Provider Mobility Counseling Provision to Older Adults: A Rural/Urban Comparison |
| Q44733827 | Hip abductor muscle volume in women with lateral hip pain: a case-controlled study |
| Q38941307 | Hip fractures in the elderly-: A Clinical Anatomy Review |
| Q64990098 | Identify CRNDE and LINC00152 as the key lncRNAs in age-related degeneration of articular cartilage through comprehensive and integrative analysis. |
| Q55351260 | Impact of Osteoarthritis on Household Catastrophic Health Expenditures in Korea. |
| Q44437119 | Impact of race and diagnostic label on older adults' emotions, illness beliefs, and willingness to help a family member with osteoarthritis |
| Q34279222 | Implementation of the simplified stochastic model of ageing for longitudinal osteoarthritis data assessment |
| Q39237159 | Improving access to better care for people with knee and/or hip pain: service evaluation of allied health professional-led primary care |
| Q39677387 | In sickness and in death: Assessing frailty in human skeletal remains |
| Q41829080 | In vivo optical imaging of early osteoarthritis using an antibody specific to damaged arthritic cartilage |
| Q37608903 | Inflammation in osteoarthritis |
| Q34983879 | Inhibitory effect of metformin and pyridoxamine in the formation of early, intermediate and advanced glycation end-products |
| Q35754521 | Interleukin-7 levels in synovial fluid increase with age and MMP-1 levels decrease with progression of osteoarthritis |
| Q37668812 | Lectin-like, oxidized low-density lipoprotein receptor-1-deficient mice show resistance to age-related knee osteoarthritis |
| Q35855720 | Lithium Chloride Dependent Glycogen Synthase Kinase 3 Inactivation Links Oxidative DNA Damage, Hypertrophy and Senescence in Human Articular Chondrocytes and Reproduces Chondrocyte Phenotype of Obese Osteoarthritis Patients. |
| Q28387689 | Low dose native type II collagen prevents pain in a rat osteoarthritis model |
| Q48092853 | Multi-echo GRE imaging of knee cartilage. |
| Q91994891 | NF-κB Signaling Pathways in Osteoarthritic Cartilage Destruction |
| Q46338170 | Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice |
| Q37230596 | Painful prosthesis: approaching the patient with persistent pain following total hip and knee arthroplasty |
| Q37274985 | Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes |
| Q34599955 | Periarticular osteophytes as an appendicular joint stress marker (JSM): analysis in a contemporary Japanese skeletal collection |
| Q34636799 | Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities |
| Q36403388 | Predicting Knee Osteoarthritis |
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| Q41190969 | Prevalence and pattern of radiographic intervertebral disc degeneration in Vietnamese: a population-based study. |
| Q55410839 | Proximal fibular osteotomy to treat medial compartment knee osteoarthritis: Preoperational factors for short-term prognosis. |
| Q37720056 | Reduced miR‑26a and miR‑26b expression contributes to the pathogenesis of osteoarthritis via the promotion of p65 translocation |
| Q34599321 | Regulation and Role of TGFβ Signaling Pathway in Aging and Osteoarthritis Joints |
| Q28540913 | Resveratrol protects chondrocytes from apoptosis via altering the ultrastructural and biomechanical properties: an AFM study |
| Q92562240 | Sarcopenia in osteoarthritis and rheumatoid arthritis: The association with self-reported fatigue, physical function and obesity |
| Q35933890 | Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health |
| Q43806702 | Socioeconomic burden of total joint arthroplasty for symptomatic hip and knee osteoarthritis in the Italian population: a 5-year analysis based on hospitalization records. |
| Q38571894 | Stem cells in degenerative orthopaedic pathologies: effects of aging on therapeutic potential. |
| Q21195248 | Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes |
| Q58734897 | Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage |
| Q61446184 | Synovial fluid monocyte/macrophage subsets and their correlation to patient-reported outcomes in osteoarthritic patients: a cohort study |
| Q47215480 | Tabetri™ (Tabebuia avellanedae Ethanol Extract) Ameliorates Osteoarthritis Symptoms Induced by Monoiodoacetate through Its Anti-Inflammatory and Chondroprotective Activities. |
| Q42556528 | Telomerase Activity in Articular Chondrocytes Is Lost after Puberty |
| Q55449322 | The Effect of Self-Management Educational Program on Pain Intensity in Elderly Patients with Knee Osteoarthritis: A Randomized Clinical Trial. |
| Q90446137 | The Role of Inflammation in the Pathogenesis of Osteoarthritis |
| Q35646408 | The Role of PPARγ in Advanced Glycation End Products-Induced Inflammatory Response in Human Chondrocytes |
| Q54959971 | The Value of Phenotypes in Knee Osteoarthritis Research. |
| Q99623803 | The association between walking speed from short- and standard-distance tests with the risk of all-cause mortality among adults with radiographic knee osteoarthritis: data from three large United States cohort studies |
| Q38852796 | The brain-joint axis in osteoarthritis: nerves, circadian clocks and beyond |
| Q27331315 | The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity. |
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