Quasispecies theory and the behavior of RNA viruses

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Quasispecies theory and the behavior of RNA viruses is …
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review articleQ7318358
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P356DOI10.1371/JOURNAL.PPAT.1001005
P932PMC publication ID2908548
P698PubMed publication ID20661479
P5875ResearchGate publication ID45367084

P50authorAdam S. LauringQ56869110
Raul AndinoQ65508584
P2860cites workQuasispecies theory in the context of population geneticsQ21283965
The error thresholdQ81268912
The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virusQ22066390
Fitness and its role in evolutionary geneticsQ22122004
The causes and consequences of HIV evolutionQ22251040
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNAQ24305266
RNA virus error catastrophe: direct molecular test by using ribavirinQ24599371
Mutational robustness can facilitate adaptationQ24624037
Turning up the volume on mutational pressure: is more of a good thing always better? (A case study of HIV-1 Vif and APOBEC3)Q24645606
Cytidine deamination induced HIV-1 drug resistanceQ24657298
Increased fidelity reduces poliovirus fitness and virulence under selective pressure in miceQ24817069
Response of foot-and-mouth disease virus to increased mutagenesis: influence of viral load and fitness in loss of infectivityQ27470003
Mutagenesis versus Inhibition in the Efficiency of Extinction of Foot-and-Mouth Disease VirusQ27477453
Negative effects of chemical mutagenesis on the adaptive behavior of vesicular stomatitis virusQ27480816
Quasispecies Structure and Persistence of RNA VirusesQ27487904
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif proteinQ27860488
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcriptsQ28179446
DNA deamination mediates innate immunity to retroviral infectionQ28179534
Evolution of digital organisms at high mutation rates leads to survival of the flattestQ28207333
Transgenic mice expressing a human poliovirus receptor: a new model for poliomyelitisQ28241524
Selforganization of matter and the evolution of biological macromoleculesQ28248277
Avian influenza A (H5N1) infection in humansQ28274603
Lethal mutagenesis of HIV with mutagenic nucleoside analogsQ28369649
Selection for robustness in mutagenized RNA virusesQ28469235
Viral population estimation using pyrosequencingQ28472641
Rates of evolutionary change in viruses: patterns and determinantsQ29616174
Quasispecies diversity determines pathogenesis through cooperative interactions in a viral populationQ29616266
Rapid evolution of RNA genomesQ29616272
Emergence of a novel swine-origin influenza A (H1N1) virus in humansQ29616833
RNA virus mutations and fitness for survivalQ29619434
Replicative fitness of historical and recent HIV-1 isolates suggests HIV-1 attenuation over time.Q30351457
Signature-tagged mutagenesis: barcoding mutants for genome-wide screensQ33265184
The fittest versus the flattest: experimental confirmation of the quasispecies effect with subviral pathogens.Q33267906
Evolution at a high imposed mutation rate: adaptation obscures the load in phage T7Q33628435
G-->A hypermutation in protease and reverse transcriptase regions of human immunodeficiency virus type 1 residing in resting CD4+ T cells in vivoQ33718616
Sequence editing by Apolipoprotein B RNA-editing catalytic component [corrected] and epidemiological surveillance of transmitted HIV-1 drug resistanceQ41868619
The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagenQ43545743
Error thresholds and the constraints to RNA virus evolutionQ44997148
Engineering attenuated virus vaccines by controlling replication fidelityQ45397402
The proportion of revertant and mutant phage in a growing population, as a function of mutation and growth rate.Q52861440
Nucleotide sequence heterogeneity of an RNA phage population.Q54586350
Selection forces and constraints on retroviral sequence variation.Q55239815
HIV-1 over time: fitness loss or robustness gain?Q57259589
Lethal mutagenesis of HIV by mutagenic ribonucleoside analogsQ73340618
Human immunodeficiency virus type 1 DNA sequences genetically damaged by hypermutation are often abundant in patient peripheral blood mononuclear cells and may be generated during near-simultaneous infection and activation of CD4(+) T cellsQ33853620
Evolvability of an RNA virus is determined by its mutational neighbourhoodQ33914492
Suppression of viral infectivity through lethal defectionQ33934382
One hundred years of poliovirus pathogenesisQ33992344
Error catastrophe and antiviral strategyQ34153584
Rapid evolution of RNA virusesQ34174014
Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexityQ34190672
Epochal evolution shapes the phylodynamics of interpandemic influenza A (H3N2) in humansQ34593954
Lassa fever. Effective therapy with ribavirinQ34694588
Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymeraseQ35012405
Mutation rate and the efficacy of antimicrobial drug treatment.Q35035358
G-->A hypermutation of the human immunodeficiency virus type 1 genome: evidence for dCTP pool imbalance during reverse transcriptionQ35154921
A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelityQ35163547
Viral error catastrophe by mutagenic nucleosidesQ35919839
Ultra-deep pyrosequencing of hepatitis B virus quasispecies from nucleoside and nucleotide reverse-transcriptase inhibitor (NRTI)-treated patients and NRTI-naive patients.Q35964704
Exotic emerging viral diseases: progress and challengesQ35971398
Foot-and-mouth disease virus evolution: exploring pathways towards virus extinctionQ36008148
Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implicationsQ36008885
Action of mutagenic agents and antiviral inhibitors on foot-and-mouth disease virus.Q36008890
Adaptive value of high mutation rates of RNA viruses: separating causes from consequencesQ36248500
What is a quasispecies?Q36433880
Viruses as quasispecies: biological implicationsQ36433889
Virus fitness: concept, quantification, and application to HIV population dynamics.Q36433892
Antiviral drug resistanceQ36452096
APOBEC-mediated viral restriction: not simply editing?Q36736677
RNA virus quasispecies populations can suppress vastly superior mutant progenyQ36796348
APOBEC proteins and intrinsic resistance to HIV-1 infectionQ37140468
Massively parallel pyrosequencing in HIV researchQ37211581
Ribavirin mode of action in chronic hepatitis C: from clinical use back to molecular mechanismsQ37340946
Contingent neutrality in competing viral populationsQ39606378
Ribavirin causes error catastrophe during Hantaan virus replication.Q39698441
Mutation Frequencies at Defined Single Codon Sites in Vesicular Stomatitis Virus and Poliovirus Can Be Increased Only Slightly by Chemical MutagenesisQ40110327
Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequenceQ40391903
KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesisQ40423448
Long-term transmission of defective RNA viruses in humans and Aedes mosquitoesQ40488747
Preextinction viral RNA can interfere with infectivityQ40579254
Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV).Q40653667
Viral quasispecies.Q40828271
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectvirusQ808
genetic variationQ349856
viral quasispeciesQ104765291
biomedical investigative techniqueQ66648976
P304page(s)e1001005
P577publication date2010-07-22
P1433published inPLOS PathogensQ283209
P1476titleQuasispecies theory and the behavior of RNA viruses
P478volume6

Reverse relations

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Q26777408Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications
Q30410029Rethinking approaches to improve the utilization of nucleic acid amplification tests for detection and characterization of influenza A in diagnostic and reference laboratories
Q28304041Rethinking quasispecies theory: From fittest type to cooperative consortia
Q38680546Reverse spillover of avian viral vaccine strains from domesticated poultry to wild birds
Q37713899Ribavirin-resistant variants of foot-and-mouth disease virus: the effect of restricted quasispecies diversity on viral virulence
Q36433974Sabin Vaccine Reversion in the Field: a Comprehensive Analysis of Sabin-Like Poliovirus Isolates in Nigeria
Q59133574Seasonal Genetic Drift of Human Influenza A Virus Quasispecies Revealed by Deep Sequencing
Q30384346Selective Bottlenecks Shape Evolutionary Pathways Taken during Mammalian Adaptation of a 1918-like Avian Influenza Virus
Q42377402Sequence-specific detection of different strains of LCMV in a single sample using tentacle probes
Q30431535Sequencing viral genomes from a single isolated plaque
Q43977684Single-Cell Virology: On-Chip Investigation of Viral Infection Dynamics
Q28483749Stochastic simulations suggest that HIV-1 survives close to its error threshold
Q56395758Strategy for efficient generation of numerous full-length cDNA clones of classical swine fever virus for haplotyping
Q92253559Stronger together: Multi-genome transmission of measles virus
Q58097211Structural and Nonstructural Genes Contribute to the Genetic Diversity of RNA Viruses
Q92290844Studying Evolutionary Adaptation of MERS-CoV
Q38949462Superinfection exclusion and the long-term survival of honey bees in Varroa-infested colonies
Q39701112Synthetic lethals in HIV: ways to avoid drug resistance : Running title: Preventing HIV resistance.
Q30423620Systematic identification of H274Y compensatory mutations in influenza A virus neuraminidase by high-throughput screening
Q37519849Systemic spread and propagation of a plant-pathogenic virus in European honeybees, Apis mellifera.
Q38047645Targeting the host or the virus: current and novel concepts for antiviral approaches against influenza virus infection
Q38894946The 5' untranslated region of a novel infectious molecular clone of the dicistrovirus cricket paralysis virus modulates infection
Q94545219The Current and Future State of Vaccines, Antivirals and Gene Therapies Against Emerging Coronaviruses
Q99605071The Genetic Diversification of a Single Bluetongue Virus Strain Using an In Vitro Model of Alternating-Host Transmission
Q98171290The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity
Q36868812The defective RNAs of Closteroviridae
Q37999021The double-edged sword: How evolution can make or break a live-attenuated virus vaccine
Q91941877The effect of genetic complementation on the fitness and diversity of viruses spreading as collective infectious units
Q36963496The emergence of drug resistant HIV variants and novel anti-retroviral therapy
Q92540850The evolution and characterization of influenza A(H7N9) virus under the selective pressure of peramivir
Q40097825The high frequency of non-aspartic acid residues at HA222 in influenza A(H1N1) 2009 pandemic viruses is associated with mortality during the upsurge of 2015: a molecular and epidemiological study from central India
Q91583736The honeybee (Apis mellifera) developmental state shapes the genetic composition of the deformed wing virus-A quasispecies during serial transmission
Q21559478The origin of novel avian influenza A (H7N9) and mutation dynamics for its human-to-human transmissible capacity
Q33781351The pepper virome: natural co-infection of diverse viruses and their quasispecies
Q34987357The plant host can affect the encapsidation of brome mosaic virus (BMV) RNA: BMV virions are surprisingly heterogeneous
Q34569574The reverse genetics applied to fish RNA viruses
Q42177302The shape-shifting quasispecies of RNA: one sequence, many functional folds
Q44843501The synergistic effect of nsP2-L618, nsP3-R117, and E2-K187 on the large plaque phenotype of chikungunya virus
Q35224851Time-calibrated phylogenomics of the classical swine fever viruses: genome-wide bayesian coalescent approach
Q57094050Time-calibrated phylogenomics of the porcine epidemic diarrhea virus: genome-wide insights into the spatio-temporal dynamics
Q37136609Towards multiscale modeling of influenza infection
Q40056648Tracing hepatitis B virus (HBV) genotype B5 (formerly B6) evolutionary history in the circumpolar Arctic through phylogeographic modelling
Q35760795Tracking Dengue Virus Intra-host Genetic Diversity during Human-to-Mosquito Transmission
Q48094480Trans-heteroclinic bifurcation: a novel type of catastrophic shift.
Q24615269Transgenerational inheritance of an acquired small RNA-based antiviral response in C. elegans
Q37360076Transstadial Transmission and Long-term Association of Crimean-Congo Hemorrhagic Fever Virus in Ticks Shapes Genome Plasticity
Q42315538TumorNext: A comprehensive tumor profiling assay that incorporates high resolution copy number analysis and germline status to improve testing accuracy
Q40711295Ultra Deep Sequencing of a Baculovirus Population Reveals Widespread Genomic Variations
Q34583054Ultra-deep mutant spectrum profiling: improving sequencing accuracy using overlapping read pairs
Q30421453Universal amplification, next-generation sequencing, and assembly of HIV-1 genomes
Q42215545Use of host-like peptide motifs in viral proteins is a prevalent strategy in host-virus interactions
Q52316681Variability Studies of Two Prunus-Infecting Fabaviruses with the Aid of High-Throughput Sequencing.
Q35422196ViQuaS: an improved reconstruction pipeline for viral quasispecies spectra generated by next-generation sequencing
Q64078035Viral RNA-dependent RNA polymerase mutants display an altered mutation spectrum resulting in attenuation in both mosquito and vertebrate hosts
Q36179597Viral population dynamics and virulence thresholds
Q86320171Viral quasispecies
Q35984339Viral quasispecies complexity measures.
Q27013917Viral quasispecies evolution
Q34525444Viral quasispecies inference from 454 pyrosequencing
Q55492199Viral quasispecies reconstruction via tensor factorization with successive read removal.
Q57285695Viroid research and its significance for RNA technology and basic biochemistry
Q36602464Viruliferous rate of small brown planthopper is a good indicator of rice stripe disease epidemics
Q42196285Virus-derived gene expression and RNA interference vector for grapevine
Q89754975West Nile Virus fidelity modulates the capacity for host cycling and adaptation
Q89457145Wide spectrum and high frequency of genomic structural variation, including transposable elements, in large double-stranded DNA viruses
Q27319869Widespread recombination, reassortment, and transmission of unbalanced compound viral genotypes in natural arenavirus infections
Q54256631Within-Host Evolution of Human Influenza Virus.
Q55370272Within-Host Recombination in the Foot-and-Mouth Disease Virus Genome.
Q35047735Within-host nucleotide diversity of virus populations: insights from next-generation sequencing
Q55500682Within-patient mutation frequencies reveal fitness costs of CpG dinucleotides and drastic amino acid changes in HIV.
Q33911231[KIL-d] Protein Element Confers Antiviral Activity via Catastrophic Viral Mutagenesis

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