scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.3390/PH3061936 |
P8608 | Fatcat ID | release_32w2updsz5aingz556x4g7dvui |
P932 | PMC publication ID | 4033960 |
P698 | PubMed publication ID | 27713335 |
P5875 | ResearchGate publication ID | 45267402 |
P2093 | author name string | Shirley ShiDu Yan | |
Heng Du | |||
P2860 | cites work | RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction | Q24315809 |
Possible role of amyloid-beta, adenine nucleotide translocase and cyclophilin-D interaction in mitochondrial dysfunction of Alzheimer's disease | Q24642355 | ||
Increased susceptibility of striatal mitochondria to calcium-induced permeability transition | Q28183063 | ||
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death | Q28242641 | ||
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death | Q28242653 | ||
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia | Q28585666 | ||
The amyloid beta protein induces oxidative damage of mitochondrial DNA. | Q53220699 | ||
Inhibition of Alzheimer's amyloid-beta peptide-induced reduction of mitochondrial membrane potential and neurotoxicity by gelsolin. | Q53267839 | ||
The cell cycle inhibitor p57(Kip2) promotes cell death via the mitochondrial apoptotic pathway. | Q53556908 | ||
Opening of the mitochondrial permeability transition pore by uncoupling or inorganic phosphate in the presence of Ca2+ is dependent on mitochondrial-generated reactive oxygen species. | Q53992783 | ||
Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice | Q58028291 | ||
A pore way to die | Q59048320 | ||
Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice | Q60796700 | ||
Chaotropic agents and increased matrix volume enhance binding of mitochondrial cyclophilin to the inner mitochondrial membrane and sensitize the mitochondrial permeability transition to [Ca2+] | Q71185931 | ||
[Comparative study between the therapeutic effects of surgical myocardial revascularization and coronary angioplasty in equivalent ischemic situations: analysis through myocardial scintigraphy with 99mTc-Sestamibi] | Q81094268 | ||
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease | Q28854335 | ||
Alzheimer's disease is a synaptic failure | Q29547670 | ||
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses | Q29615239 | ||
Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro | Q30306800 | ||
Biochemical analysis of cybrids expressing mitochondrial DNA from Contursi kindred Parkinson's subjects | Q30307412 | ||
Mitochondrial DNA--related mitochondrial dysfunction in neurodegenerative diseases | Q30308782 | ||
Amyloid beta-peptide disrupts mitochondrial membrane lipid and protein structure: protective role of tauroursodeoxycholate. | Q30327817 | ||
Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease | Q30489145 | ||
A connection between the mitochondrial permeability transition pore, autophagy, and cerebral amyloidogenesis. | Q33332678 | ||
Mitochondrial Ca2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDs | Q33354062 | ||
Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide | Q34032925 | ||
Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity | Q34548519 | ||
Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis | Q34627577 | ||
Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis | Q35762075 | ||
Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model | Q35831042 | ||
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae | Q36856671 | ||
Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease | Q37013705 | ||
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins | Q37039531 | ||
Inhibition of mitochondrial permeability transition pore opening by ischemic preconditioning is probably mediated by reduction of oxidative stress rather than mitochondrial protein phosphorylation. | Q37069429 | ||
{beta}-Amyloid impairs AMPA receptor trafficking and function by reducing Ca2+/calmodulin-dependent protein kinase II synaptic distribution | Q37155459 | ||
The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice | Q37261104 | ||
Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease | Q37261203 | ||
Mitochondria, mitochondrial DNA and Alzheimer's disease. What comes first? | Q37294059 | ||
Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease | Q37321251 | ||
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease | Q37463481 | ||
Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons. | Q37478112 | ||
Calcium elevation in mitochondria is the main Ca2+ requirement for mitochondrial permeability transition pore (mPTP) opening. | Q39839664 | ||
PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death | Q39873016 | ||
PINK1 mutants associated with recessive Parkinson's disease are defective in inhibiting mitochondrial release of cytochrome c. | Q40091994 | ||
Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress. | Q40162080 | ||
Coenzyme Q10 protects SHSY5Y neuronal cells from beta amyloid toxicity and oxygen-glucose deprivation by inhibiting the opening of the mitochondrial permeability transition pore | Q40250514 | ||
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression | Q40301497 | ||
The mitochondrial phosphate carrier interacts with cyclophilin D and may play a key role in the permeability transition | Q40421507 | ||
Induction of cytochrome c-mediated apoptosis by amyloid beta 25-35 requires functional mitochondria | Q40744342 | ||
Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury | Q41601375 | ||
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease | Q41945324 | ||
Role of cyclophilin D-dependent mitochondrial permeability transition in glutamate-induced calcium deregulation and excitotoxic neuronal death | Q42019992 | ||
Beta-amyloid enhances intracellular calcium rises mediated by repeated activation of intracellular calcium stores and nicotinic receptors in acutely dissociated rat basal forebrain neurons | Q42520656 | ||
In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP. | Q42920869 | ||
Intrathecal cyclosporin prolongs survival of late-stage ALS mice | Q43543805 | ||
Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities | Q43858152 | ||
Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A. | Q44049211 | ||
Effect of amyloid beta-peptide on permeability transition pore: a comparative study. | Q44059809 | ||
Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses. | Q44066992 | ||
Effect of beta-amyloid peptide fragment 25-35 on nonselective permeability of mitochondria | Q44085981 | ||
Amyloid beta-peptide promotes permeability transition pore in brain mitochondria | Q44093453 | ||
Amyloid beta peptide induces cytochrome C release from isolated mitochondria | Q44190608 | ||
Disulfonic stilbenes prevent beta-amyloid (25-35) neuronal toxicity in rat cortical cultures | Q44369857 | ||
Ca(2+) binding to c-state of adenine nucleotide translocase (ANT)-surrounding cardiolipins enhances (ANT)-Cys(56) relative mobility: a computational-based mitochondrial permeability transition study | Q44532678 | ||
Free Radical Reactions of Methionine in Peptides: Mechanisms Relevant to β-Amyloid Oxidation and Alzheimer's Disease | Q44643195 | ||
Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against beta-amyloid peptide toxicity. | Q44720684 | ||
FK506 and a nonimmunosuppressant derivative reduce axonal and myelin damage in experimental autoimmune encephalomyelitis: neuroimmunophilin ligand-mediated neuroprotection in a model of multiple sclerosis | Q44973931 | ||
Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis | Q44979511 | ||
The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway. | Q45022345 | ||
ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction | Q45234437 | ||
Neuroprotective effect of cyclosporine and FK506 against 3-nitropropionic acid induced cognitive dysfunction and glutathione redox in rat: possible role of nitric oxide | Q46050636 | ||
Age-related calcium changes, oxyradical damage, caspase activation and nuclear condensation in hippocampal neurons in response to glutamate and beta-amyloid | Q46512988 | ||
Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice | Q46737335 | ||
Synaptic mitochondria are more susceptible to Ca2+overload than nonsynaptic mitochondria | Q46975941 | ||
Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease | Q47714762 | ||
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease | Q47754186 | ||
Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease | Q48069116 | ||
Evidence of oxidative stress-induced BNIP3 expression in amyloid beta neurotoxicity | Q48287665 | ||
Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons. | Q48398341 | ||
Role of oxidative stress on beta-amyloid neurotoxicity elicited during impairment of energy metabolism in the hippocampus: protection by antioxidants | Q48576311 | ||
Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease | Q48865828 | ||
Downregulation of amyloid precursor protein (APP) expression following post-traumatic cyclosporin-A administration | Q49090806 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Alzheimer's disease | Q11081 |
P304 | page(s) | 1936-1948 | |
P577 | publication date | 2010-06-14 | |
P1433 | published in | Pharmaceuticals | Q15750667 |
P1476 | title | Unlocking the Door to Neuronal Woes in Alzheimer's Disease: Aβ and Mitochondrial Permeability Transition Pore | |
P478 | volume | 3 |
Q42316680 | Asiaticoside ameliorates β-amyloid-induced learning and memory deficits in rats by inhibiting mitochondrial apoptosis and reducing inflammatory factors |
Q35807409 | Mitochondria as a therapeutic target for aging and neurodegenerative diseases |
Q48284335 | Mitochondrial Perturbation in Alzheimer's Disease and Diabetes |
Search more.