| scholarly article | Q13442814 |
| P2093 | author name string | Nickolay Brustovetsky | |
| Tatiana Brustovetsky | |||
| Martin Crompton | |||
| Michela Capano | |||
| Janet M Dubinsky | |||
| Kevin J Purl | |||
| P2860 | cites work | A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Q25938984 |
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| Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration | Q30992818 | ||
| Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore | Q31942254 | ||
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| Protein aggregation and pathogenesis of Huntington's disease: mechanisms and correlations | Q34081469 | ||
| The mitochondrial potassium cycle | Q34499054 | ||
| Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni | Q38340859 | ||
| Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase | Q38559578 | ||
| The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism | Q38608271 | ||
| Assay of picomole amounts of ATP, ADP, and AMP using the luciferase enzyme system | Q39072565 | ||
| 3-Nitropropionic acid exacerbates N-methyl-D-aspartate toxicity in striatal culture by multiple mechanisms. | Q39449440 | ||
| Role of ubiquinone in the mitochondrial generation of hydrogen peroxide | Q40005741 | ||
| The mitochondrial permeability transition. | Q40462729 | ||
| Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines. | Q40721588 | ||
| Neuronal necrosis and apoptosis: two distinct events induced by exposure to glutamate or oxidative stress. | Q41308388 | ||
| Mitochondrial heterogeneity in the brain at the cellular level | Q41719646 | ||
| Mitochondrial channel activity studied by patch-clamping mitoplasts | Q42014495 | ||
| The reversible Ca2+-induced permeabilization of rat liver mitochondria | Q42067210 | ||
| Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia. | Q42438521 | ||
| Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress | Q42818406 | ||
| Regulation of the mitochondrial matrix volume in vivo and in vitro. The role of calcium | Q42853961 | ||
| Liver mitochondrial pyrophosphate concentration is increased by Ca2+ and regulates the intramitochondrial volume and adenine nucleotide content | Q42856797 | ||
| Inhibition of mitochondrial complex II induces a long-term potentiation of NMDA-mediated synaptic excitation in the striatum requiring endogenous dopamine. | Q43662825 | ||
| Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain. | Q43664667 | ||
| Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease | Q43669934 | ||
| DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria | Q43777368 | ||
| Oxidative stress in Ca(2+)-induced membrane permeability transition in brain mitochondria | Q43830043 | ||
| Modulation of cyclophilin gene expression by N-4-(hydroxyphenyl)retinamide: association with reactive oxygen species generation and apoptosis | Q43864576 | ||
| Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugation | Q43950113 | ||
| Effect of aging and acetyl-L-carnitine on energetic and cholinergic metabolism in rat brain regions | Q44190948 | ||
| The inner mitochondrial membrane contains ion-conducting channels similar to those found in bacteria. | Q44810762 | ||
| Effect of metal cations on the inhibition of adenine nucleotide translocation by acyl-CoA | Q45173595 | ||
| The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A. | Q45215970 | ||
| Metabotropic glutamate receptors and cell-type-specific vulnerability in the striatum: implication for ischemia and Huntington's disease | Q45298860 | ||
| Coenzyme Q10 and remacemide hydrochloride ameliorate motor deficits in a Huntington's disease transgenic mouse model | Q45304699 | ||
| Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease. | Q45305438 | ||
| Oxidative metabolism of nonsynaptic mitochondria isolated from rat brain hippocampus: a comparative regional study | Q48097336 | ||
| Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability | Q48198160 | ||
| Does GFAP mRNA and mitochondrial benzodiazepine receptor binding detect serotonergic neuronal degeneration in rat? | Q48211276 | ||
| Phenobarbital and 6-aminonicotinamide effect on cerebral enzymatic activities related to energy metabolism in different rat brain areas | Q48253404 | ||
| Decreases in mouse brain NAD+ and ATP induced by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP): prevention by the poly(ADP-ribose) polymerase inhibitor, benzamide | Q48363902 | ||
| The effect of age on the activity of enzymes of peroxide metabolism in rat brain | Q48369490 | ||
| Calcium-induced activation of the mitochondrial permeability transition in hippocampal neurons | Q48386508 | ||
| Mitochondria and neuronal glutamate excitotoxicity | Q48406562 | ||
| Beneficial effects of naftidrofuryl oxalate on brain regional energy metabolism after microsphere-induced cerebral embolism | Q48518049 | ||
| Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat. | Q48546984 | ||
| Reduced activity of the pyruvate dehydrogenase complex but not cytochrome c oxidase is associated with neuronal loss in the striatum following short-term forebrain ischemia | Q48580834 | ||
| Influence of intermittent hypoxia and pyrimidinic nucleosides on cerebral enzymatic activities related to energy transduction | Q48637560 | ||
| The activities of some energy-metabolising enzymes in nonsynaptic (free) and synaptic mitochondria derived from selected brain regions | Q48673801 | ||
| Structural and functional aspects of the respiratory chain of synaptic and nonsynaptic mitochondria derived from selected brain regions | Q48765883 | ||
| On the regulation of K+ uniport in intact mitochondria by adenine nucleotides and nucleotide analogs. | Q50785794 | ||
| Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function? | Q52123671 | ||
| The permeability transition in heart mitochondria is regulated synergistically by ADP and cyclosporin A. | Q54060908 | ||
| The presence of two classes of high-affinity cyclosporin A binding sites in mitochondria. Evidence that the minor component is involved in the opening of an inner-membrane Ca(2+)-dependent pore. | Q54085821 | ||
| Changes induced by aging and drug treatment on cerebral enzymatic antioxidant system | Q60722292 | ||
| Prominence of direct entorhinal-CA1 pathway activation in sensorimotor and cognitive tasks revealed by 2-DG functional mapping in nonhuman primate | Q62168601 | ||
| Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state | Q66944710 | ||
| Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress | Q67493487 | ||
| Regional changes in the cellular level of adenine nucleotides in ischemic rat brain subjected to single embolization | Q68393935 | ||
| Temporal evolution of regional energy metabolism following focal cerebral ischemia in the rat | Q68437185 | ||
| Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria | Q69070569 | ||
| Involvement of the ADP/ATP carrier in calcium-induced perturbations of the mitochondrial inner membrane permeability: importance of the orientation of the nucleotide binding site | Q69837943 | ||
| Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria | Q70080329 | ||
| Mitochondrial ADP/ATP carrier can be reversibly converted into a large channel by Ca2+ | Q71186017 | ||
| Enzymatic profile of mitochondria isolated from selected brain regions of young adult and one-year-old rats | Q71214917 | ||
| Regional energy balance in rat brain after transient forebrain ischemia | Q71689939 | ||
| Evidence for the Involvement of a Membrane-Associated Cyclosporin-A-Binding Protein in the Ca2+-Activated Inner Membrane Pore of Heart Mitochondria | Q71845731 | ||
| Selective Inhibition of the Tricarboxylic Acid Cycle of GABAergic Neurons with 3‐Nitropropionic Acid In Vivo | Q71978455 | ||
| Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid | Q72098398 | ||
| Influence of divalent cations on the reconstituted ADP, ATP exchange | Q72864621 | ||
| Dual responses of CNS mitochondria to elevated calcium | Q73338084 | ||
| Proton selective substate of the mitochondrial permeability transition pore: regulation by the redox state of the electron transport chain | Q77333095 | ||
| Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization | Q95810356 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | mitochondrion | Q39572 |
| striatum | Q1319792 | ||
| P304 | page(s) | 4858-4867 | |
| P577 | publication date | 2003-06-15 | |
| P1433 | published in | Journal of Neuroscience | Q1709864 |
| P1476 | title | Increased susceptibility of striatal mitochondria to calcium-induced permeability transition | |
| P478 | volume | 23 |
| Q33539988 | A mathematical model of mitochondrial swelling |
| Q30577415 | Axon degeneration and PGC-1α-mediated protection in a zebrafish model of α-synuclein toxicity |
| Q38700215 | Beyond muscles: The untapped potential of creatine |
| Q55514851 | Brain Energy and Oxygen Metabolism: Emerging Role in Normal Function and Disease. |
| Q36019780 | Brief mitochondrial inhibition causes lasting changes in motor behavior and corticostriatal synaptic physiology in the Fischer 344 rat. |
| Q35893954 | Ca(2+) handling in isolated brain mitochondria and cultured neurons derived from the YAC128 mouse model of Huntington's disease |
| Q36935277 | Calcium-induced precipitate formation in brain mitochondria: composition, calcium capacity, and retention |
| Q37237452 | Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration |
| Q50088379 | Cause or compensation?-Altered neuronal Ca2+ handling in Huntington's disease. |
| Q33862724 | Circulating levels of sirtuin 4, a potential marker of oxidative metabolism, related to coronary artery disease in obese patients suffering from NAFLD, with normal or slightly increased liver enzymes. |
| Q42788385 | Concentration dependent effect of calcium on brain mitochondrial bioenergetics and oxidative stress parameters |
| Q37114413 | Cyclophilin D is expressed predominantly in mitochondria of gamma-aminobutyric acidergic interneurons |
| Q57021971 | Deletion of mitochondrial calcium uniporter incompletely inhibits calcium uptake and induction of the permeability transition pore in brain mitochondria |
| Q39273647 | Development or disease: duality of the mitochondrial permeability transition pore |
| Q46255661 | Experimental autoimmune encephalomyelitis from a tissue energy perspective. |
| Q30450114 | Fluorescence response of human HER2+ cancer- and MCF-12F normal cells to 200MHz ultrasound microbeam stimulation: a preliminary study of membrane permeability variation |
| Q27684278 | High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules |
| Q35664881 | Impaired import: how huntingtin harms |
| Q36297458 | Increased Expression of Osteopontin in the Degenerating Striatum of Rats Treated with Mitochondrial Toxin 3-Nitropropionic Acid: A Light and Electron Microscopy Study |
| Q46191238 | Increased expression and intramitochondrial translocation of cyclophilin-D associates with increased vulnerability of the permeability transition pore to stress-induced opening during compensated ventricular hypertrophy |
| Q41993741 | Isolation of mitochondria from the CNS. |
| Q28208193 | Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice |
| Q64387394 | Metabolic Reprogramming in Astrocytes Distinguishes Region-Specific Neuronal Susceptibility in Huntington Mice |
| Q28394301 | Metabolism in HD: still a relevant mechanism? |
| Q64074984 | Mitochondrial Dysfunction in Huntington's Disease; Interplay Between HSF1, p53 and PGC-1α Transcription Factors |
| Q60949053 | Mitochondrial Metabolism in Major Neurological Diseases |
| Q48284335 | Mitochondrial Perturbation in Alzheimer's Disease and Diabetes |
| Q37747170 | Mitochondrial bioenergetics and dynamics in Huntington's disease: tripartite synapses and selective striatal degeneration |
| Q38170006 | Mitochondrial dysfunction and NAD(+) metabolism alterations in the pathophysiology of acute brain injury |
| Q37672741 | Mitochondrial medicine for neurodegenerative diseases |
| Q35799121 | Mitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease |
| Q37427280 | Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease. |
| Q27023850 | Mitochondrial permeability transition pore is a potential drug target for neurodegeneration |
| Q57170869 | Mitochondrial permeability transition pore: a potential drug target for neurodegeneration |
| Q45307199 | Mitochondrial sensitivity and altered calcium handling underlie enhanced NMDA-induced apoptosis in YAC128 model of Huntington's disease. |
| Q53588721 | Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death. |
| Q39891449 | Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux |
| Q37308357 | Mutant huntingtin and mitochondrial dysfunction |
| Q35282959 | NLRP3 inflammasome contributes to inflammation after intracerebral hemorrhage. |
| Q91972707 | Neurodegenerative Diseases - Is Metabolic Deficiency the Root Cause? |
| Q36571516 | Optical and pharmacological tools to investigate the role of mitochondria during oxidative stress and neurodegeneration. |
| Q39035184 | Oxidative metabolism and Ca2+ handling in striatal mitochondria from YAC128 mice, a model of Huntington's disease |
| Q37237423 | Probing the molecular mechanisms of neuronal degeneration: importance of mitochondrial dysfunction and calcineurin activation. |
| Q34556735 | Protective effect of metformin on gentamicin-induced vestibulotoxicity in rat primary cell culture. |
| Q35891839 | Protective roles of CNS mitochondria |
| Q42019992 | Role of cyclophilin D-dependent mitochondrial permeability transition in glutamate-induced calcium deregulation and excitotoxic neuronal death |
| Q37557789 | Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease |
| Q36597920 | Selective neuronal degeneration in Huntington's disease |
| Q41967848 | The challenge in translating basic research discoveries to treatment of Huntington disease |
| Q28072937 | The chicken or the egg: mitochondrial dysfunction as a cause or consequence of toxicity in Huntington's disease |
| Q36476846 | The functional and neuroprotective actions of Neu2000, a dual-acting pharmacological agent, in the treatment of acute spinal cord injury |
| Q37765841 | The interrelationship between mitochondrial dysfunction and transcriptional dysregulation in Huntington disease |
| Q35219902 | The striatum is highly susceptible to mitochondrial oxidative phosphorylation dysfunctions |
| Q33664175 | Unlocking the Door to Neuronal Woes in Alzheimer's Disease: Aβ and Mitochondrial Permeability Transition Pore |
| Q93140140 | Voluntary exercise normalizes the proteomic landscape in muscle and brain and improves the phenotype of progeroid mice |
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