| scholarly article | Q13442814 |
| P50 | author | Andrew P Halestrap | Q38321371 |
| P2093 | author name string | Davidson AM | |
| P2860 | cites work | Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin | Q24338951 |
| The Ca2+-induced membrane transition in mitochondria. I. The protective mechanisms | Q28305411 | ||
| The Ca2+-induced membrane transition in mitochondria. II. Nature of the Ca2+ trigger site | Q28306067 | ||
| Stimulation of mitochondrial calcium ion efflux by thiol-specific reagents and by thyroxine. The relationship to adenosine diphosphate retention and to mitochondrial permeability | Q28317553 | ||
| Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins | Q29618460 | ||
| Linear versus circular polarization of head coils: comparison on phantoms and in the clinic | Q33929451 | ||
| Adenine nucleotide-induced contraction on the inner mitochondrial membrane. II. Effect of bongkrekic acid | Q36194514 | ||
| Adenine nucleotide-induced contraction of the inner mitochondrial membrane. I. General characterization | Q36194574 | ||
| The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism | Q38608271 | ||
| The cyclosporins | Q38616662 | ||
| Intramitochondrial phospholipase activity and the effects of Ca2+ plus N-ethylmaleimide on mitochondrial function | Q39282481 | ||
| Solute carriers involved in energy transfer of mitochondria form a homologous protein family | Q39506741 | ||
| Lipid peroxidation in mitochondria | Q39578534 | ||
| A heart mitochondrial Ca2(+)-dependent pore of possible relevance to re-perfusion-induced injury. Evidence that ADP facilitates pore interconversion between the closed and open states | Q41782125 | ||
| CALCIUM ION ACCUMULATION AND VOLUME CHANGES OF ISOLATED LIVER MITOCHONDRIA. CALCIUM ION-INDUCED SWELLING | Q41944132 | ||
| Partial inhibition by cyclosporin A of the swelling of liver mitochondria in vivo and in vitro induced by sub-micromolar [Ca2+], but not by butyrate. Evidence for two distinct swelling mechanisms | Q42140765 | ||
| Evidence for the presence of a reversible Ca2+-dependent pore activated by oxidative stress in heart mitochondria | Q42163611 | ||
| The regulation of the oxidation of fatty acids and other substrates in rat heart mitochondria by changes in the matrix volume induced by osmotic strength, valinomycin and Ca2+. | Q42164796 | ||
| Inhibition of mitochondrial-matrix inorganic pyrophosphatase by physiological [Ca2+], and its role in the hormonal regulation of mitochondrial matrix volume | Q42175976 | ||
| The transmembrane arrangement of the ADP/ATP carrier as elucidated by the lysine reagent pyridoxal 5-phosphate | Q42206202 | ||
| Inorganic pyrophosphate is located primarily in the mitochondria of the hepatocyte and increases in parallel with the decrease in light-scattering induced by gluconeogenic hormones, butyrate and ionophore A23187. | Q42502449 | ||
| Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress | Q42818406 | ||
| Regulation of the mitochondrial matrix volume in vivo and in vitro. The role of calcium | Q42853961 | ||
| Liver mitochondrial pyrophosphate concentration is increased by Ca2+ and regulates the intramitochondrial volume and adenine nucleotide content | Q42856797 | ||
| In vitro alteration of the size of the liver mitochondrial adenine nucleotide pool: correlation with respiratory functions | Q47292399 | ||
| Demonstration of the relation between the adenine nucleotide carrier and the structural changes of mitochondria as induced by adenosine 5'-diphosphate | Q47896352 | ||
| Cyclosporin A-binding protein (cyclophilin) of Neurospora crassa. One gene codes for both the cytosolic and mitochondrial forms. | Q48313697 | ||
| Increased permeability of mitochondria during Ca2+ release induced by t-butyl hydroperoxide or oxalacetate. the effect of ruthenium red. | Q51860736 | ||
| The control of Ca2+ release from heart mitochondria | Q52532670 | ||
| Rapid preparation of metabolically active mitochondria from control and hormone-treated rat liver cells. | Q53765905 | ||
| Autophagic-lysosomal and mitochondrial sequestration of [14C]sucrose. Density gradient distribution of sequestered radioactivity. | Q54439611 | ||
| In vitro toxicity assessment of cyclosporin A and its analogs in a primary rat hepatocyte culture model | Q67974612 | ||
| Beneficial effect of cyclosporine pretreatment in preventing ischemic damage to the liver in dogs | Q67995338 | ||
| Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria | Q69070569 | ||
| Effects of phospholipase A2 inhibitors on ruthenium red-induced Ca2+ release from mitochondria | Q69380469 | ||
| Involvement of the ADP/ATP carrier in calcium-induced perturbations of the mitochondrial inner membrane permeability: importance of the orientation of the nucleotide binding site | Q69837943 | ||
| Impact on energy metabolism of quantitative and functional cyclosporine-induced damage of kidney mitochondria | Q69844118 | ||
| Kinetic evidence for a heart mitochondrial pore activated by Ca2+, inorganic phosphate and oxidative stress. A potential mechanism for mitochondrial dysfunction during cellular Ca2+ overload | Q69846273 | ||
| Characterization of pyrophosphate exchange by the reconstituted adenine nucleotide translocator from mitochondria | Q70080458 | ||
| Oxygen gradients: the problem of hypoxia | Q70191695 | ||
| Action of cyclosporine on mitochondrial calcium fluxes | Q70355565 | ||
| Adenine nucleotide transport during cardiac ischemia | Q70992967 | ||
| Decrease in mitochondrial levels of adenine nucleotides and concomitant mitochondrial dysfunction in ischemic rat liver | Q71070769 | ||
| Changes in mitochondrial lipids of rat kidney during ischemia | Q71206818 | ||
| The relationship between mitochondrial membrane permeability, membrane potential, and the retention of Ca2+ by mitochondria | Q71302464 | ||
| Mechanism(s) of altered mitochondrial calcium transport in acutely ischemic canine hearts | Q72871724 | ||
| Intramitochondrial adenine nucleotides and energy-linked functions of heart mitochondria | Q72913746 | ||
| Opposite effects of bongkrekic acid and atractyloside on the adenine nucleotides induced mitochondrial volume changes and on the efflux of adenine nucleotides | Q77917205 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | mitochondrion | Q39572 |
| P304 | page(s) | 153-160 | |
| P577 | publication date | 1990-05-01 | |
| P1433 | published in | Biochemical Journal | Q864221 |
| P1476 | title | Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni | |
| P478 | volume | 268 |
| Q41841377 | 'Pore' formation is not required for the hydroperoxide-induced Ca2+ release from rat liver mitochondria |
| Q33772259 | (-)-Deprenyl inhibits vascular hyperpermeability after hemorrhagic shock |
| Q95848141 | A 20/20 view of ANT function in mitochondrial biology and necrotic cell death |
| Q37419777 | A CaPful of mechanisms regulating the mitochondrial permeability transition |
| Q64261125 | ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore |
| Q37771263 | Adenine nucleotide translocator as a regulator of mitochondrial function: implication in the pathogenesis of metabolic syndrome |
| Q28346385 | Adenine nucleotide translocator isoforms 1 and 2 are differently distributed in the mitochondrial inner membrane and have distinct affinities to cyclophilin D |
| Q40770185 | Age-related changes in the mitochondrial depolarization induced by oxidative injury in human peripheral blood leukocytes |
| Q44859595 | An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury |
| Q37679901 | Antioxidant and mitochondrial protective effects of oxidized metabolites of oltipraz |
| Q35117847 | Apoptosis and necrosis in health and disease: Role of mitochondria |
| Q36382247 | Apoptosis and necrosis in the liver: a tale of two deaths? |
| Q40874973 | Apoptosis in factor-dependent haematopoietic cells is linked to calcium-sensitive mitochondrial rearrangements and cytoskeletal modulation |
| Q28540094 | Attenuation of skeletal muscle and renal injury to the lower limb following ischemia-reperfusion using mPTP inhibitor NIM-811 |
| Q35633387 | Axonal degeneration is mediated by the mitochondrial permeability transition pore. |
| Q30311030 | Basic science of closed head injuries and spinal cord injuries |
| Q40254604 | Bcl-xL mediates RIPK3-dependent necrosis in M. tuberculosis-infected macrophages |
| Q100526035 | Bisindolylpyrrole triggers transient mitochondrial permeability transitions to cause apoptosis in a VDAC1/2 and cyclophilin D-dependent manner via the ANT-associated pore |
| Q44846041 | Brain-derived respiring mitochondria exhibit homogeneous, complete and cyclosporin-sensitive permeability transition |
| Q47656401 | CONTINUOUS INFUSION OF PHENELZINE, CYCLOSPORINE A OR THE COMBINATION: EVALUATION OF MITOCHONDRIAL BIOENERGETICS, OXIDATIVE DAMAGE AND CYTOSKELETAL DEGRADATION FOLLOWING SEVERE CONTROLLED CORTICAL IMPACT TRAUMATIC BRAIN INJURY IN RATS. |
| Q27026987 | CaMKIIdelta subtypes: localization and function |
| Q34112324 | Calcium and mitochondrial reactive oxygen species generation: how to read the facts. |
| Q38781704 | Calcium and reactive oxygen species in regulation of the mitochondrial permeability transition and of programmed cell death in yeast. |
| Q35753892 | Calcium ions and oxidative cell injury |
| Q26786470 | Calcium signaling as a mediator of cell energy demand and a trigger to cell death |
| Q41816900 | Calcium-dependent opening of a non-specific pore in the mitochondrial inner membrane is inhibited at pH values below 7. Implications for the protective effect of low pH against chemical and hypoxic cell damage |
| Q30365091 | Calcium-independent disruption of microtubule dynamics by nanosecond pulsed electric fields in U87 human glioblastoma cells. |
| Q37768703 | Cardioprotection in the clinical setting |
| Q47816919 | Carrier and channel properties of the mitochondrial transporters: physiology and pathology? |
| Q46448005 | Cd2+-induced swelling-contraction dynamics in isolated kidney cortex mitochondria: role of Ca2+ uniporter, K+ cycling, and protonmotive force |
| Q26823103 | Cell death disguised: The mitochondrial permeability transition pore as the c-subunit of the F(1)F(O) ATP synthase |
| Q33718426 | Channel formation by yeast F-ATP synthase and the role of dimerization in the mitochondrial permeability transition |
| Q30195176 | Channels in mitochondrial membranes: knowns, unknowns, and prospects for the future. |
| Q71979171 | Channel‐specific induction of the cyclosporine a‐sensitive mitochondrial permeability transition by menadione |
| Q37375152 | Characteristics and possible functions of mitochondrial Ca(2+) transport mechanisms |
| Q37610877 | Characterization of functionally distinct mitochondrial subpopulations |
| Q28554706 | Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson's Disease |
| Q58454367 | Chemical Modification of Arginines by 2,3-Butanedione and Phenylglyoxal Causes Closure of the Mitochondrial Permeability Transition Pore |
| Q34212159 | Chronic ethanol consumption enhances sensitivity to Ca(2+)-mediated opening of the mitochondrial permeability transition pore and increases cyclophilin D in liver |
| Q42064418 | Ciclosporin does not attenuate intracranial hypertension in rats with acute hyperammonaemia |
| Q39040000 | Ciclosporin to Protect Renal function In Cardiac Surgery (CiPRICS): a study protocol for a double-blind, randomised, placebo-controlled, proof-of-concept study |
| Q48864569 | Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore |
| Q28261309 | Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases |
| Q53973311 | Conditions allowing different states of ATP- and GDP-induced permeability in mitochondria from different strains of Saccharomyces cerevisiae. |
| Q42222947 | Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats |
| Q43485162 | Copper sensitizes the mitochondrial permeability transition to carboxytractyloside and oleate |
| Q37196065 | Crosstalk signaling between mitochondrial Ca2+ and ROS. |
| Q37297666 | Cyclophilin A as a New Therapeutic Target for Hepatitis C Virus-induced Hepatocellular Carcinoma |
| Q35086991 | Cyclophilin D and the mitochondrial permeability transition in kidney proximal tubules after hypoxic and ischemic injury |
| Q24598637 | Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice |
| Q39923466 | Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis |
| Q37660604 | Cyclophilin D in mitochondrial pathophysiology |
| Q37114413 | Cyclophilin D is expressed predominantly in mitochondria of gamma-aminobutyric acidergic interneurons |
| Q37158908 | Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells |
| Q60954151 | Cyclophilin D, Somehow a Master Regulator of Mitochondrial Function |
| Q36251975 | Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy |
| Q34152722 | Cyclophilin D-sensitive mitochondrial permeability transition in adult human brain and liver mitochondria |
| Q28572316 | Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis |
| Q33815808 | Cyclophilins and their possible role in the stress response |
| Q36024824 | Cyclosporin A and cardioprotection: from investigative tool to therapeutic agent. |
| Q48098658 | Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons |
| Q43676695 | Cyclosporin A induces the opening of a potassium-selective channel in higher plant mitochondria |
| Q53543594 | Cyclosporin A inhibits programmed cell death and cytochrome c release induced by fusicoccin in sycamore cells. |
| Q48436702 | Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. |
| Q35044717 | Cyclosporine A regulate oxidative stress-induced apoptosis in cardiomyocytes: mechanisms via ROS generation, iNOS and Hsp70 |
| Q42138238 | Cytochrome c release from isolated rat liver mitochondria can occur independently of outer-membrane rupture: possible role of contact sites |
| Q34307101 | Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice |
| Q34264428 | Delocalized lipophilic cations selectively target the mitochondria of carcinoma cells |
| Q40676646 | Delta 9-tetrahydrocannabinol disrupts mitochondrial function and cell energetics |
| Q45028100 | Diazoxide-mediated preconditioning against apoptosis involves activation of cAMP-response element-binding protein (CREB) and NFkappaB. |
| Q48198160 | Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability |
| Q41869861 | Differential effects of zidovudine and zidovudine triphosphate on mitochondrial permeability transition and oxidative phosphorylation |
| Q28569445 | Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition |
| Q74744617 | Dose-related inversion of cinnarizine and flunarizine effects on mitochondrial permeability transition |
| Q73338084 | Dual responses of CNS mitochondria to elevated calcium |
| Q53914925 | Effect of noise exposure on rat cardiac peripheral benzodiazepine receptors. |
| Q40421777 | Effects of organophosphorus compounds on ATP production and mitochondrial integrity in cultured cells |
| Q45743761 | Effects of the membrane potential upon the Ca2+ - and cumene hydroperoxide-induced permeabilization of the inner mitochondrial membrane |
| Q38550517 | Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart |
| Q35781096 | Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock |
| Q71845731 | Evidence for the Involvement of a Membrane-Associated Cyclosporin-A-Binding Protein in the Ca2+-Activated Inner Membrane Pore of Heart Mitochondria |
| Q42127417 | Evidence for the existence of [3H]-trimetazidine binding sites involved in the regulation of the mitochondrial permeability transition pore |
| Q36701743 | Extent of mitochondrial hexokinase II dissociation during ischemia correlates with mitochondrial cytochrome c release, reactive oxygen species production, and infarct size on reperfusion |
| Q53957729 | Fatty acid-induced uncoupling of oxidative phosphorylation is partly due to opening of the mitochondrial permeability transition pore. |
| Q27004110 | From ATP to PTP and Back: A Dual Function for the Mitochondrial ATP Synthase |
| Q28280396 | From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state |
| Q34807984 | Functional and pharmacological characteristics of permeability transition in isolated human heart mitochondria. |
| Q41138584 | Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin |
| Q91785525 | Gallic acid protects rat liver mitochondria ex vivo from bisphenol A induced oxidative stress mediated damages |
| Q36216023 | Genetic ablation of calcium-independent phospholipase A(2)γ (iPLA(2)γ) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release |
| Q46085120 | Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice |
| Q36259123 | Genetic dissection of the permeability transition pore |
| Q44957415 | Glutamate interacts with VDAC and modulates opening of the mitochondrial permeability transition pore |
| Q35619935 | Glutathione preconditioning ameliorates mitochondria dysfunction during warm pulmonary ischemia-reperfusion injury |
| Q41774727 | Glycine preconditioning to ameliorate pulmonary ischemia reperfusion injury in rats |
| Q34766031 | Green tea polyphenols stimulate mitochondrial biogenesis and improve renal function after chronic cyclosporin a treatment in rats |
| Q33529841 | Hepatic stimulator substance mitigates hepatic cell injury through suppression of the mitochondrial permeability transition |
| Q48107838 | High cyclophilin D content of synaptic mitochondria results in increased vulnerability to permeability transition. |
| Q27684278 | High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules |
| Q35666094 | Human coronavirus-induced neuronal programmed cell death is cyclophilin d dependent and potentially caspase dispensable |
| Q41098425 | Human papillomavirus (HPV) 16 E6 sensitizes cells to atractyloside-induced apoptosis: role of p53, ICE-like proteases and the mitochondrial permeability transition |
| Q57881630 | Hypothyroidism renders liver mitochondria resistant to the opening of membrane permeability transition pore |
| Q36748823 | Identification and comparative analysis of the peptidyl-prolyl cis/trans isomerase repertoires of H. sapiens, D. melanogaster, C. elegans, S. cerevisiae and Sz. pombe |
| Q33942032 | Identification of a ryanodine receptor in rat heart mitochondria |
| Q33972218 | Identifying the components of the elusive mitochondrial permeability transition pore |
| Q42976462 | Impact of adenosine nucleotide translocase (ANT) proline isomerization on Ca2+-induced cysteine relative mobility/mitochondrial permeability transition pore |
| Q44587600 | In Saccharomyces cerevisiae, cations control the fate of the energy derived from oxidative metabolism through the opening and closing of the yeast mitochondrial unselective channel |
| Q42808298 | In brain mitochondria the branched-chain fatty acid phytanic acid impairs energy transduction and sensitizes for permeability transition |
| Q44559473 | In vivo application of mitochondrial pore inhibitors blocks the induction of apoptosis in axotomized neonatal facial motoneurons |
| Q41364300 | In vivo opening of the mitochondrial permeability transition pore in a rat model of ventricular fibrillation and closed-chest resuscitation |
| Q77936668 | In vivo prevention of adriamycin cardiotoxicity by cyclosporin A or FK506 |
| Q78106692 | In vivo prevention of cyclophosphamide-induced Ca2+ dependent damage of rat heart and liver mitochondria by cyclosporin A |
| Q46939197 | Increased mitochondrial calcium coexists with decreased reperfusion injury in postconditioned (but not preconditioned) hearts |
| Q28183063 | Increased susceptibility of striatal mitochondria to calcium-induced permeability transition |
| Q58454372 | Induction of the mitochondrial permeability transition by N-ethylmaleimide depends on secondary oxidation of critical thiol groups. Potentiation by copper-ortho-phenanthroline without dimerization of the adenine nucleotide translocase |
| Q93137353 | Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD |
| Q73849006 | Inhibitory effect of dipyridamole and its derivatives on lipid peroxidation in mitochondria |
| Q35672374 | Interplay between mitochondria and cellular calcium signalling |
| Q46823572 | Intra-mitochondrial degradation of Tim23 curtails the survival of cells rescued from apoptosis by caspase inhibitors |
| Q37160450 | Intralipid, a clinically safe compound, protects the heart against ischemia-reperfusion injury more efficiently than cyclosporine-A. |
| Q44918596 | Intrinsic differences in brain and spinal cord mitochondria: Implication for therapeutic interventions. |
| Q91973112 | Investigating the Mitochondrial Permeability Transition Pore in Disease Phenotypes and Drug Screening |
| Q24644090 | Investigation of Debio 025, a cyclophilin inhibitor, in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy |
| Q57956360 | Involvement of Cyclophilin D in the Activation of A mitochondrial Pore by Ca2+ and Oxidant Stress |
| Q37575814 | Involvement of the mitochondrial permeability transition pore in chronic ethanol-mediated liver injury in mice |
| Q44401253 | Ischaemic preconditioning inhibits opening of mitochondrial permeability transition pores in the reperfused rat heart |
| Q44515300 | Ischemic pre-conditioning preserves brain mitochondrial functions during the middle cerebral artery occlusion in rat. |
| Q43713944 | Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis |
| Q73168250 | Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria |
| Q30309593 | Lithium inhibits aluminum-induced apoptosis in rabbit hippocampus, by preventing cytochrome c translocation, Bcl-2 decrease, Bax elevation and caspase-3 activation |
| Q42426530 | Long-chain ceramide is a potent inhibitor of the mitochondrial permeability transition pore |
| Q53902212 | Long-chain fatty acids promote opening of the reconstituted mitochondrial permeability transition pore. |
| Q44300116 | Matrix volume measurements challenge the existence of diazoxide/glibencamide-sensitive KATP channels in rat mitochondria |
| Q48336425 | Mechanisms of neuronal damage in brain hypoxia/ischemia: focus on the role of mitochondrial calcium accumulation |
| Q43628696 | Methylmercury and H(2)O(2) provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis |
| Q37922118 | Microparticles: a critical component in the nexus between inflammation, immunity, and thrombosis |
| Q38952396 | Milestones and recent discoveries on cell death mediated by mitochondria and their interactions with biologically active amines |
| Q36827897 | Mitochondria and cardioprotection |
| Q37439453 | Mitochondria and reperfusion injury of the heart--a holey death but not beyond salvation |
| Q58611546 | Mitochondria as a therapeutic target for common pathologies |
| Q34264465 | Mitochondria as target for antiischemic drugs |
| Q43028145 | Mitochondria from the salt-tolerant yeast Debaryomyces hansenii (halophilic organelles?). |
| Q34478951 | Mitochondria in Ca2+ signaling and apoptosis |
| Q61443749 | Mitochondria-targeted cyclosporin A delivery system to treat myocardial ischemia reperfusion injury of rats |
| Q38920740 | Mitochondrial Ca2+ and regulation of the permeability transition pore |
| Q42747745 | Mitochondrial Ca2+ influx and efflux rates in guinea pig cardiac mitochondria: low and high affinity effects of cyclosporine A |
| Q38786513 | Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State. |
| Q47980436 | Mitochondrial bioenergetics decay in aging: beneficial effect of melatonin |
| Q35625774 | Mitochondrial biogenesis and function in Arabidopsis |
| Q34478937 | Mitochondrial calcium signaling driven by the IP3 receptor |
| Q34621961 | Mitochondrial carriers and pores: key regulators of the mitochondrial apoptotic program? |
| Q39238972 | Mitochondrial complex I inhibitors, acetogenins, induce HepG2 cell death through the induction of the complete apoptotic mitochondrial pathway. |
| Q48329711 | Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells. |
| Q36366491 | Mitochondrial control of nuclear apoptosis. |
| Q89480053 | Mitochondrial dysfunction and neurodegenerative proteinopathies: mechanisms and prospects for therapeutic intervention |
| Q37864604 | Mitochondrial dysfunction and nicotinamide dinucleotide catabolism as mechanisms of cell death and promising targets for neuroprotection |
| Q49886209 | Mitochondrial dysfunction in diabetic kidney disease |
| Q42596013 | Mitochondrial effects with ceramide-induced cardiac apoptosis are different from those of palmitate |
| Q63190269 | Mitochondrial formation of hydrogen peroxide is causally linked to the antimycin A-mediated prevention of tert -butylhydroperoxide-induced U937 cell death |
| Q53945860 | Mitochondrial function as a determinant of recovery or death in cell response to injury. |
| Q35553668 | Mitochondrial function: the heart of myocardial preservation |
| Q43803434 | Mitochondrial injury by disulfiram: two different mechanisms of the mitochondrial permeability transition. |
| Q68211975 | Mitochondrial inner membrane permeability changes induced by octadecadienoic acid hydroperoxide. Role of mitochondrial GSH pool |
| Q34083604 | Mitochondrial intermembrane junctional complexes and their role in cell death |
| Q37621278 | Mitochondrial involvement in cardiac apoptosis during ischemia and reperfusion: can we close the box? |
| Q38737214 | Mitochondrial involvement in myocyte death and heart failure |
| Q36358060 | Mitochondrial medicine: pharmacological targeting of mitochondria in disease |
| Q33836193 | Mitochondrial membrane potential and the permeability transition in excitotoxicity |
| Q41977320 | Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion |
| Q48973665 | Mitochondrial oxidative stress induced by Ca2+ and monoamines: different behaviour of liver and brain mitochondria in undergoing permeability transition |
| Q47796571 | Mitochondrial permeability transition as induced by cross-linking of the adenine nucleotide translocase |
| Q35968596 | Mitochondrial permeability transition in CNS trauma: cause or effect of neuronal cell death? |
| Q28218571 | Mitochondrial permeability transition in acute neurodegeneration |
| Q39220742 | Mitochondrial permeability transition in cardiac ischemia-reperfusion: whether cyclophilin D is a viable target for cardioprotection? |
| Q34395582 | Mitochondrial permeability transition in the crustacean Artemia franciscana: absence of a calcium-regulated pore in the face of profound calcium storage |
| Q48203904 | Mitochondrial permeability transition induced DNA-fragmentation in the rat hippocampus following hypoglycemia. |
| Q39568317 | Mitochondrial permeability transition pore (MPTP) desensitization increases sea urchin spermatozoa fertilization rate. |
| Q41619720 | Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability |
| Q35120719 | Mitochondrial permeability transition: a common pathway to necrosis and apoptosis |
| Q73693534 | Mitochondrial protonophoric activity induced by a thyromimetic fatty acid analogue |
| Q33913079 | Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release |
| Q47848301 | Mitochondrial swelling and oxygen consumption during respiratory state 4 induced by phospholipase A2 isoforms isolated from the South American rattlesnake (Crotalus durissus terrificus) venom |
| Q34277591 | Mitofusins and the mitochondrial permeability transition: the potential downside of mitochondrial fusion |
| Q44392110 | Modeling the transmembrane arrangement of the uncoupling protein UCP1 and topological considerations of the nucleotide-binding site |
| Q50127791 | Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore. II. The minimal requirements for pore induction underscore a key role for transmembrane electrical potential, matrix pH, and matrix Ca2+ |
| Q38244750 | Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury |
| Q38204222 | Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition |
| Q95848133 | Molecular nature and regulation of the mitochondrial permeability transition pore(s), drug target(s) in cardioprotection |
| Q90204047 | Mortalin (HSPA9) facilitates BRAF-mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability |
| Q37103238 | N-Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore |
| Q36972843 | NIM811 (N-methyl-4-isoleucine cyclosporine), a mitochondrial permeability transition inhibitor, attenuates cholestatic liver injury but not fibrosis in mice |
| Q47291176 | NIM811, a mitochondrial permeability transition inhibitor, prevents mitochondrial depolarization in small-for-size rat liver grafts |
| Q87906376 | Neuronal Cell Death |
| Q60302116 | Neuroprotective Effects of Cyclosporine in a Porcine Pre-Clinical Trial of Focal Traumatic Brain Injury |
| Q39753504 | Neuroprotective effects of Tacrolimus (FK-506) and Cyclosporin (CsA) in oxidative injury |
| Q33588472 | Not all mitochondrial carrier proteins support permeability transition pore formation: no involvement of uncoupling protein 1. |
| Q44068280 | Novel mechanism of Vitamin E protection against cyclosporine A cytotoxicity in cultured rat hepatocytes |
| Q42828732 | On the interactions of Ca2+ and cyclosporin A with a mitochondrial inner membrane pore: a study using cobaltammine complex inhibitors of the Ca2+ uniporter |
| Q40719289 | On the involvement of a mitochondrial pore in reperfusion injury |
| Q57881658 | On the mechanism by which 6-ketocholestanol protects mitochondria against uncoupling-induced Ca2+ efflux |
| Q46161413 | On the mechanism of the failure of mitochondrial function in isolated guinea-pig myocytes subjected to a Ca2+ overload |
| Q61192773 | On the properties of calcium-induced permeability transition in neonatal heart mitochondria |
| Q57881648 | On the protection by inorganic phosphate of calcium-induced membrane permeability transition |
| Q30414295 | Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle |
| Q53894867 | Oxidative stress and adenine nucleotide control of mitochondrial permeability transition. |
| Q46751286 | Oxidative stress damage in the protozoan parasite Trypanosoma cruzi is inhibited by Cyclosporin A. |
| Q36474703 | Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy |
| Q41683038 | Partial contribution of mitochondrial permeability transition to t-butyl hydroperoxide-induced cell death |
| Q42140765 | Partial inhibition by cyclosporin A of the swelling of liver mitochondria in vivo and in vitro induced by sub-micromolar [Ca2+], but not by butyrate. Evidence for two distinct swelling mechanisms |
| Q62632583 | Periodate-oxidized ATP stimulates the permeability transition of rat liver mitochondria |
| Q43552483 | Peripheral-type benzodiazepine receptor ligands: mitochondrial permeability transition induction in rat cardiac tissue. |
| Q41456668 | Permeability transition pore of the inner mitochondrial membrane can operate in two open states with different selectivities |
| Q43621652 | Peroxynitrite promotes mitochondrial permeability transition-dependent rapid U937 cell necrosis: survivors proliferate with kinetics superimposable on those of untreated cells |
| Q58454377 | Perspectives on the mitochondrial permeability transition |
| Q39674331 | Pharmacologic Targeting or Genetic Deletion of Mitochondrial Cyclophilin D Protects from NSAID-Induced Small Intestinal Ulceration in Mice |
| Q91860378 | Pharmacology of mitochondrial permeability transition pore inhibitors |
| Q28594159 | Phosphate is essential for inhibition of the mitochondrial permeability transition pore by cyclosporin A and by cyclophilin D ablation |
| Q36429969 | Phosphate is not an absolute requirement for the inhibitory effects of cyclosporin A or cyclophilin D deletion on mitochondrial permeability transition |
| Q38094017 | Physiologic functions of cyclophilin D and the mitochondrial permeability transition pore. |
| Q36193286 | Physiological and pathological roles of the mitochondrial permeability transition pore in the heart |
| Q42363155 | Physiological roles of the mitochondrial permeability transition pore |
| Q39539986 | Platinum(II) chloride indenyl complexes: electrochemical and biological evaluation |
| Q38306338 | Possible involvement of the adenine nucleotide translocase in the activation of the permeability transition pore induced by cadmium |
| Q46648121 | Possible mechanism for formation and regulation of the palmitate-induced cyclosporin A-insensitive mitochondrial pore |
| Q31123008 | Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria |
| Q73571778 | Prednisolone and azathioprine worsen the cyclosporine A-induced oxidative phosphorylation decrease of kidney mitochondria |
| Q37237423 | Probing the molecular mechanisms of neuronal degeneration: importance of mitochondrial dysfunction and calcineurin activation. |
| Q88723805 | Programmed necrosis in cardiomyocytes: mitochondria, death receptors and beyond |
| Q50095703 | Programmed necrosis in heart disease: Molecular mechanisms and clinical implications |
| Q46953928 | Prooxidant-induced Ca2+ release from liver mitochondria. Specific versus nonspecific pathways |
| Q35842069 | Properties of Ca(2+) transport in mitochondria of Drosophila melanogaster |
| Q28246454 | Properties of a cyclosporin-insensitive permeability transition pore in yeast mitochondria |
| Q44530084 | Protection provided by cyclosporin A against excitotoxic neuronal death is genotype dependent |
| Q39154358 | Protective effects of piperine against copper-ascorbate induced toxic injury to goat cardiac mitochondria in vitro |
| Q28583648 | Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin |
| Q48136811 | Purinergic receptor-stimulated IP3-mediated Ca2+ release enhances neuroprotection by increasing astrocyte mitochondrial metabolism during aging. |
| Q42796649 | Pyrophosphate metabolism in the perfused heart and isolated heart mitochondria and its role in regulation of mitochondrial function by calcium |
| Q39965236 | Quantification of active mitochondrial permeability transition pores using GNX-4975 inhibitor titrations provides insights into molecular identity |
| Q91590333 | ROS-related mitochondrial dysfunction in skeletal muscle of an ALS mouse model during the disease progression |
| Q40272184 | Re-evaluation of the distinction between type I and type II cells: the necessary role of the mitochondria in both the extrinsic and intrinsic signaling pathways upon Fas receptor activation |
| Q90355066 | Real-time local oxygen measurements for high resolution cellular imaging |
| Q35813196 | Rebamipide suppresses diclofenac-induced intestinal permeability via mitochondrial protection in mice |
| Q40615810 | Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane |
| Q44353042 | Reciprocal effects between spermine and Mg2+ on their movements across the mitochondrial membrane |
| Q38551862 | Reconstituted adenine nucleotide translocase forms a channel for small molecules comparable to the mitochondrial permeability transition pore |
| Q42120347 | Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel |
| Q52123671 | Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function? |
| Q37240968 | Regulation and pharmacology of the mitochondrial permeability transition pore |
| Q31859419 | Regulation of cyclosporin A sensitive mitochondrial permeability transition by the redox state of pyridine nucleotides |
| Q41786008 | Regulation of mitochondrial permeability transition pore by PINK1. |
| Q33851480 | Regulation of necrotic cell death: p53, PARP1 and cyclophilin D-overlapping pathways of regulated necrosis? |
| Q73103519 | Regulation of tumor necrosis factor cytotoxicity by calcineurin |
| Q74760844 | Reoxygenation-induced mitochondrial damage is caused by the Ca2+-dependent mitochondrial inner membrane permeability transition |
| Q50537973 | Reversible inhibition of hydrogen peroxide elimination by calcium in brain mitochondria. |
| Q43077004 | Role of arachidonic acid, lipoxygenase, and mitochondrial depolarization in reperfusion arrhythmias |
| Q24534680 | Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore |
| Q28307050 | Roles of cyclophilins in cancers and other organ systems |
| Q28372846 | Rotenone and pyruvate prevent the tert-butylhydroperoxide-induced necrosis of U937 cells and allow them to proliferate |
| Q44438019 | S-15176 inhibits mitochondrial permeability transition via a mechanism independent of its antioxidant properties |
| Q44049211 | Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A. |
| Q24658163 | Selective degradation of mitochondria by mitophagy |
| Q58454399 | Selective inhibition of the mitochondrial permeability transition pore at the oxidation-reduction sensitive dithiol by monobromobimane |
| Q60216938 | Spermine binding to liver mitochondria deenergized by ruthenium red plus either FCCP or antimycin A |
| Q33437998 | Stimulation of glutamate receptors in cultured hippocampal neurons causes Ca2+-dependent mitochondrial contraction |
| Q44305130 | Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: evidence for differentially sensitive populations in the cortex and hippocampus |
| Q48530059 | Synaptic Mitochondria Sustain More Damage than Non-Synaptic Mitochondria after Traumatic Brain Injury and Are Protected by Cyclosporine A. |
| Q37388699 | TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions. |
| Q41787336 | Tacrolimus and sirolimus decrease oxidative phosphorylation of isolated rat kidney mitochondria |
| Q38234720 | Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease |
| Q28083205 | Targeting Mitochondria and Reactive Oxygen Species-Driven Pathogenesis in Diabetic Nephropathy |
| Q37862534 | Targeting the mitochondrial permeability transition: cardiac ischemia-reperfusion versus carcinogenesis |
| Q36695966 | The Immunosuppressant FK506 Inhibits Amino Acid Import in Saccharomyces cerevisiae |
| Q37136752 | The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis: A COMPARATIVE STUDY WITH THE PROTEASOME INHIBITOR BORTEZOMIB |
| Q38945146 | The Mitochondrial Permeability Transition Pore and ATP Synthase. |
| Q36146320 | The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology. |
| Q26772318 | The Permeability Transition in Plant Mitochondria: The Missing Link |
| Q74028489 | The anti-oxidant ebselen antagonizes the release of the apoptogenic factor cytochrome c induced by Fe2+/citrate in rat liver mitochondria |
| Q48603348 | The endocannabinoid 2-arachidonoylglicerol decreases calcium induced cytochrome c release from liver mitochondria. |
| Q38518265 | The importance of hypoxia and extra physiologic oxygen shock/stress for collection and processing of stem and progenitor cells to understand true physiology/pathology of these cells ex vivo. |
| Q36744211 | The mitochondrial K(ATP) channel--fact or fiction? |
| Q44175602 | The mitochondrial megachannel is the permeability transition pore |
| Q73407306 | The mitochondrial membrane permeability transition induced by inorganic phosphate or inorganic arsenate. A comparative study |
| Q28280478 | The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy |
| Q36775895 | The mitochondrial permeability transition in neurologic disease |
| Q36733673 | The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis |
| Q29614183 | The mitochondrial permeability transition pore and its role in cell death |
| Q38274962 | The mitochondrial permeability transition pore and its role in myocardial ischemia reperfusion injury. |
| Q29397664 | The mitochondrial permeability transition pore may comprise VDAC molecules |
| Q38245433 | The mitochondrial permeability transition: a current perspective on its identity and role in ischaemia/reperfusion injury. |
| Q77314788 | The mitochondrial permeability transition: from biochemical curiosity to pathophysiological mechanism |
| Q40421507 | The mitochondrial phosphate carrier interacts with cyclophilin D and may play a key role in the permeability transition |
| Q37195017 | The molecular composition of the mitochondrial permeability transition pore |
| Q41852932 | The neuroprotective effects of Coccomyxa gloeobotrydiformis on the ischemic stroke in a rat model |
| Q54073607 | The nonspecific inner membrane pore of liver mitochondria: modulation of cyclosporin sensitivity by ADP at carboxyatractyloside-sensitive and insensitive sites. |
| Q30473178 | The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism. |
| Q38003544 | The permeability transition pore as a Ca(2+) release channel: new answers to an old question |
| Q41456661 | The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal |
| Q34648839 | The permeability transition pore complex: another view. |
| Q36799163 | The permeability transition pore in cell death |
| Q53961431 | The permeability transition pore opening in intact mitochondria and submitochondrial particles. |
| Q54085821 | The presence of two classes of high-affinity cyclosporin A binding sites in mitochondria. Evidence that the minor component is involved in the opening of an inner-membrane Ca(2+)-dependent pore. |
| Q52714916 | The release of cytochrome c and the regulation of the programmed cell death progress in the endosperm of winter wheat (Triticum aestivum L.) under waterlogging. |
| Q42167900 | The role of cyclophilin D in learning and memory |
| Q38804933 | The role of glycine in regulated cell death |
| Q34581118 | The role of mitochondria in protection of the heart by preconditioning. |
| Q28237910 | The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore |
| Q55406381 | The source of cell-free mitochondrial DNA in trauma and potential therapeutic strategies. |
| Q41140036 | Transient induction of the mitochondrial permeability transition by uncoupler plus a Ca2+-specific chelator |
| Q57881687 | Triphenyltin as inductor of mitochondrial membrane permeability transition |
| Q34239873 | Two close, too close: sarcoplasmic reticulum-mitochondrial crosstalk and cardiomyocyte fate |
| Q43908015 | VDAC and peripheral channelling complexes in health and disease. |
| Q38867968 | VDAC regulates AAC-mediated apoptosis and cytochrome c release in yeast |
| Q34658211 | What is the mitochondrial permeability transition pore? |
| Q36099938 | What makes the mitochondria a killer? Can we condition them to be less destructive? |
| Q36855831 | cDNA cloning of rat mitochondrial cyclophilin. |
| Q44620607 | l-Deprenyl as an inhibitor of menadione-induced permeability transition in liver mitochondria |
| Q24301260 | s-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin |
| Q43728413 | tert-Butylhydroperoxide induces peroxynitrite-dependent mitochondrial permeability transition leading PC12 cells to necrosis |
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