scholarly article | Q13442814 |
P50 | author | John Ioannidis | Q6251482 |
Tommaso A. Dragani | Q39898827 | ||
P2093 | author name string | Antonella Galvan | |
P2860 | cites work | Finding the missing heritability of complex diseases | Q22122198 |
Is replication the gold standard for validating genome-wide association findings? | Q24288730 | ||
Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases | Q24289213 | ||
Exome sequencing identifies the cause of a mendelian disorder | Q24607742 | ||
New common variants affecting susceptibility to basal cell carcinoma | Q24615109 | ||
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer | Q24627043 | ||
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study | Q24644661 | ||
Genome-wide association study identifies novel breast cancer susceptibility loci | Q24645441 | ||
Common 5p15.33 and 6p21.33 variants influence lung cancer risk | Q24646182 | ||
Autosomal dominant polycystic kidney disease: the last 3 years | Q24656249 | ||
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma | Q24657797 | ||
Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland | Q28140600 | ||
Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations | Q28215462 | ||
Multiple newly identified loci associated with prostate cancer susceptibility | Q28268180 | ||
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer | Q28303909 | ||
Cigarette smoking and subsequent risk of lung cancer in men and women: analysis of a prospective cohort study | Q28386695 | ||
A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study | Q28943278 | ||
Multiple loci identified in a genome-wide association study of prostate cancer | Q28943507 | ||
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer | Q29417081 | ||
Common genetic variation and human traits | Q29614445 | ||
Integrated detection and population-genetic analysis of SNPs and copy number variation | Q29614584 | ||
Replication validity of genetic association studies | Q29615456 | ||
Genome-wide significance for dense SNP and resequencing data | Q31142964 | ||
Genomewide high-density SNP linkage analysis of non-BRCA1/2 breast cancer families identifies various candidate regions and has greater power than microsatellite studies | Q33296082 | ||
Genome-wide linkage scan for colorectal cancer susceptibility genes supports linkage to chromosome 3q. | Q33326484 | ||
A genome-wide association study of testicular germ cell tumor | Q33855633 | ||
A major lung cancer susceptibility locus maps to chromosome 6q23-25. | Q33910059 | ||
CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies | Q33910280 | ||
Localization of a susceptibility gene for familial nonmedullary thyroid carcinoma to chromosome 2q21 | Q34044355 | ||
Common familial colorectal cancer linked to chromosome 7q31: a genome-wide analysis | Q34082534 | ||
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). | Q34085748 | ||
The molecular genetics of Usher syndrome | Q34202837 | ||
A gene predisposing to familial thyroid tumors with cell oxyphilia maps to chromosome 19p13.2. | Q34388217 | ||
Papillary thyroid carcinoma associated with papillary renal neoplasia: genetic linkage analysis of a distinct heritable tumor syndrome | Q34509119 | ||
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer | Q34631785 | ||
Polygenic determinants of severe hypertriglyceridemia | Q34656651 | ||
Validating, augmenting and refining genome-wide association signals | Q34976245 | ||
Next generation disparities in human genomics: concerns and remedies | Q35008340 | ||
A genome wide linkage analysis in Swedish families with hereditary non-familial adenomatous polyposis/non-hereditary non-polyposis colorectal cancer | Q35760274 | ||
Lynch syndrome genes | Q36246487 | ||
The genetic concept of vitiligo | Q36248261 | ||
Commentary: grading the credibility of molecular evidence for complex diseases | Q36422605 | ||
Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility | Q36582802 | ||
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33. | Q36670312 | ||
A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2 | Q36690009 | ||
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations | Q36878530 | ||
Calibration of credibility of agnostic genome-wide associations | Q37117080 | ||
Genome-wide linkage scan reveals three putative breast-cancer-susceptibility loci | Q37156098 | ||
A genome wide linkage search for breast cancer susceptibility genes | Q37272982 | ||
Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042. | Q37300024 | ||
Reaching new heights: insights into the genetics of human stature | Q37308087 | ||
Genome-wide association study identifies three loci associated with melanoma risk | Q37341178 | ||
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. | Q37356243 | ||
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. | Q37369631 | ||
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. | Q37422744 | ||
Schizophrenia genetics: new insights from new approaches | Q37483078 | ||
Nicotine dependence may link the 15q25 locus to lung cancer risk. | Q37632080 | ||
An evaluation of statistical approaches to rare variant analysis in genetic association studies | Q39941009 | ||
Letter: Genetic heterogeneity recognized by Waardenburgh in 1935 | Q40623664 | ||
Linkage analysis in a large Swedish family supports the presence of a susceptibility locus for adenoma and colorectal cancer on chromosome 9q22.32-31.1. | Q43170770 | ||
Population-wide generalizability of genome-wide discovered associations | Q43725415 | ||
Prediction of Lynch syndrome in consecutive patients with colorectal cancer | Q43786046 | ||
Genome-wide linkage screen for testicular germ cell tumour susceptibility loci | Q44816258 | ||
Researching genetic versus nongenetic determinants of disease: a comparison and proposed unification | Q44932696 | ||
Frequency of hereditary non-polyposis colorectal cancer and other colorectal cancer familial forms in Spain: a multicentre, prospective, nationwide study | Q45015698 | ||
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. | Q50674084 | ||
Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish Family-Cancer Database | Q52041429 | ||
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 | Q56436562 | ||
Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer | Q56436732 | ||
Evidence for a colorectal cancer susceptibility locus on chromosome 3q21-q24 from a high-density SNP genome-wide linkage scan | Q56437172 | ||
Evidence of Linkage to Chromosome 9q22.33 in Colorectal Cancer Kindreds from the United Kingdom | Q56437189 | ||
Diet, nutrition and cancer: public, media and scientific confusion | Q56994796 | ||
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21 | Q57078703 | ||
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk | Q57092250 | ||
Common variants on chromosome 5p12 confer susceptibility to estrogen receptor–positive breast cancer | Q57251792 | ||
The emerging landscape of breast cancer susceptibility | Q57272203 | ||
Genome-wide scanning for linkage in Finnish breast cancer families | Q57274804 | ||
When the smoke clears .. | Q59071759 | ||
Mapping a New Familial Thyroid Epithelial Neoplasia Susceptibility Locus to Chromosome 8p23.1-p22 by High-Density Single-Nucleotide Polymorphism Genome-Wide Linkage Analysis | Q61785513 | ||
Genome-wide linkage scan for breast cancer susceptibility loci in Swedish hereditary non-BRCA1/2 families: suggestive linkage to 10q23.32-q25.3. | Q79435491 | ||
Merging and emerging cohorts: necessary but not sufficient | Q79579692 | ||
Current clinical selection strategies for identification of hereditary non-polyposis colorectal cancer families are inadequate: a meta-analysis | Q79786009 | ||
Linkage and association: basic concepts | Q80930851 | ||
Differential features of colorectal cancers fulfilling Amsterdam criteria without involvement of the mutator pathway | Q81390831 | ||
Polygenes, risk prediction, and targeted prevention of breast cancer | Q81523323 | ||
Genetic risk information for common diseases may indeed be already useful for prevention and early detection | Q82426328 | ||
P433 | issue | 3 | |
P921 | main subject | genome-wide association study | Q1098876 |
P304 | page(s) | 132-141 | |
P577 | publication date | 2010-01-26 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Trends in Genetics | Q2451468 |
P1476 | title | Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer | |
P478 | volume | 26 |
Q41832329 | A Comparison of Methods Sensitive to Interactions With Small Main Effects |
Q33996733 | A bayesian method for evaluating and discovering disease loci associations |
Q34235767 | A comparative analysis of methods for predicting clinical outcomes using high-dimensional genomic datasets |
Q33915049 | A compendium of genome-wide associations for cancer: critical synopsis and reappraisal |
Q34584127 | A fast algorithm for learning epistatic genomic relationships |
Q28943309 | A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum |
Q34548834 | A pri-miR-218variant and risk of cervical carcinoma in Chinese women |
Q37768765 | A systems-biology approach to modular genetic complexity |
Q36984352 | A weighted U statistic for association analyses considering genetic heterogeneity |
Q33727999 | ACN9 and alcohol dependence: family-based association analysis in multiplex alcohol dependence families |
Q34163470 | Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibility |
Q35799313 | Analyzing heterogeneous complexity in complementary and alternative medicine research: a systems biology solution via parsimony phylogenetics |
Q34268264 | Artificial neural networks modeling gene-environment interaction |
Q57763078 | Association of lung adenocarcinoma clinical stage with gene expression pattern in noninvolved lung tissue |
Q83467037 | Association study by genetic clustering detects multiple inflammatory response loci in non-inbred mice |
Q48323081 | Behavior genetics and postgenomics |
Q36746480 | Binomial Mixture Model Based Association Testing to Account for Genetic Heterogeneity for GWAS. |
Q84444139 | CCL2 -2518 A/G single nucleotide polymorphism as a risk factor for breast cancer |
Q28389946 | Cancer evolution and individual susceptibility |
Q42411337 | Cancer heterogeneity: origins and implications for genetic association studies |
Q26853446 | Child Development and Molecular Genetics: 14 Years Later |
Q90460653 | Clonal Evolution of TP53 c.375+1G>A Mutation in Pre- and Post- Neo-Adjuvant Chemotherapy (NACT) Tumor Samples in High-Grade Serous Ovarian Cancer (HGSOC) |
Q34632989 | Colorectal adenomas and cancer link to chromosome 13q22.1-13q31.3 in a large family with excess colorectal cancer |
Q54569106 | Common genetic variants at 1q22 and 10q23 and gastric cancer susceptibility in a Korean population. |
Q46722386 | Complex genetic control of lung tumorigenesis in resistant mice strains. |
Q39797690 | Congenic mapping and allele-specific alteration analysis of Stmm1 locus conferring resistance to early-stage chemically induced skin papillomas |
Q28742717 | Database of genetic studies of bipolar disorder |
Q38001652 | Deciphering the complexities of human diseases and disorders by coupling induced-pluripotent stem cells and systems genetics |
Q36031435 | Discovering causal interactions using Bayesian network scoring and information gain |
Q35431483 | Does Radioiodine Therapy in Patients with Differentiated Thyroid Cancer Increase the Frequency of Another Malignant Neoplasm? |
Q34767345 | Estimating single nucleotide polymorphism associations using pedigree data: applications to breast cancer |
Q26852716 | Etiologic field effect: reappraisal of the field effect concept in cancer predisposition and progression |
Q35625062 | Evaluating de novo locus-disease discoveries in GWAS using the signal-to-noise ratio |
Q30912379 | Evaluation of a two-stage framework for prediction using big genomic data |
Q98303264 | Expanding cancer predisposition genes with ultra-rare cancer-exclusive human variations |
Q28389772 | Extensive genomic variability of knops blood group polymorphisms is associated with sickle cell disease in Africa |
Q39214172 | Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes. |
Q47657039 | Functional variants in the low-density lipoprotein receptor gene are associated with clear cell renal cell carcinoma susceptibility. |
Q37281843 | Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer |
Q36710655 | Genetic variants and their interactions in disease risk prediction - machine learning and network perspectives |
Q35076098 | Genome wide association studies in presence of misclassified binary responses |
Q36480665 | Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review |
Q92528590 | Genomic Regions Associated with IgE Levels against Culicoides spp. Antigens in Three Horse Breeds |
Q37996736 | Host–pathogen interactions revealed by human genome-wide surveys |
Q41953629 | Identification of Stmm3 locus conferring resistance to late-stage chemically induced skin papillomas on mouse chromosome 4 by congenic mapping and allele-specific alteration analysis |
Q92740717 | Identification of genetic polymorphisms modulating nausea and vomiting in two series of opioid-treated cancer patients |
Q47070107 | Identification of seven genes essential for male fertility through a genome-wide association study of non-obstructive azoospermia and RNA interference-mediated large-scale functional screening in Drosophila |
Q64113992 | Identifying Multi-Omics Causers and Causal Pathways for Complex Traits |
Q42723558 | Integrative genomic analysis for the discovery of biomarkers in prostate cancer. |
Q38966664 | Interaction Landscape of Inherited Polymorphisms with Somatic Events in Cancer. |
Q35196550 | LEAP: biomarker inference through learning and evaluating association patterns |
Q35857072 | Learning Predictive Interactions Using Information Gain and Bayesian Network Scoring |
Q34237589 | Low-pass genome-wide sequencing and variant inference using identity-by-descent in an isolated human population |
Q85397309 | MYH rs3219476 and rs3219472 polymorphisms and risk of cholangiocarcinoma |
Q42398020 | Major milestones in translational oncology. |
Q34573232 | Making sense of intratumor genetic heterogeneity: altered frequency of androgen receptor CAG repeat length variants in breast cancer tissues. |
Q46663786 | Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer |
Q26774610 | Multiple primary colorectal cancer: Individual or familial predisposition? |
Q30421894 | No boundaries: genomes, organisms, and ecological interactions responsible for divergence and reproductive isolation |
Q59137957 | Pathway-based subnetworks enable cross-disease biomarker discovery |
Q33750178 | Phenotypic complexity, measurement bias, and poor phenotypic resolution contribute to the missing heritability problem in genetic association studies |
Q51035956 | Polymorphisms in the kinesin-like factor 1 B gene and risk of epithelial ovarian cancer in Eastern Chinese women. |
Q46256009 | Polymorphisms of the Interleukin 6 gene contribute to cervical cancer susceptibility in Eastern Chinese women |
Q28397236 | Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project |
Q37269846 | Population growth inflates the per-individual number of deleterious mutations and reduces their mean effect |
Q34989679 | Potentially functional polymorphisms in the CASP7 gene contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population |
Q38044219 | Profiling of Ileal Carcinoids |
Q37012718 | Rapid dissemination of RET-transgene-driven melanoma in the presence of non-obese diabetic alleles: Critical roles of Dectin-1 and Nitric-oxide synthase type 2. |
Q85033778 | Recent progress in genetic variants associated with cancer and their implications in diagnostics development |
Q30346987 | Regularized Machine Learning in the Genetic Prediction of Complex Traits |
Q33787026 | Replication of genome-wide discovered breast cancer risk loci in the Cypriot population |
Q99208455 | Set-based genetic association and interaction tests for survival outcomes based on weighted V statistics |
Q34775103 | Special considerations in prognostic research in cancer involving genetic polymorphisms |
Q51643106 | The Restricted Partition Method |
Q36317944 | The Ser326Cys polymorphism of hOGG1 is associated with intrahepatic cholangiocarcinoma susceptibility in a Chinese population |
Q34007629 | The blood exposome and its role in discovering causes of disease |
Q36925187 | The genetics of breast cancer: risk factors for disease |
Q34279459 | The hunt for gene effects pertinent to behavioral traits and psychiatric disorders: From mouse to human |
Q34182007 | The population genetics of chronic kidney disease: insights from the MYH9–APOL1 locus |
Q34791981 | The use of genomic information to optimize cancer chemotherapy |
Q35067663 | To control false positives in gene-gene interaction analysis: two novel conditional entropy-based approaches |
Q34537807 | Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence |
Q35312645 | Unraveling heterogeneous susceptibility and the evolution of breast cancer using a systems biology approach |
Q36253844 | Using haplotype analysis to elucidate significant associations between genes and Hodgkin lymphoma |
Q38638960 | Verification of Three-Phase Dependency Analysis Bayesian Network Learning Method for Maize Carotenoid Gene Mining. |
Q46543455 | What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations |
Q36412250 | XRCC1 Arg194Trp and Arg399Gln polymorphisms and risk of extrahepatic cholangiocarcinoma: a hospital-based case-control study in China |
Q64992147 | [Recent progress in genetic variants associated with cancer and their implications in diagnostics development]. |
Search more.