| Q39635492 | A Comparison Study of Fixed and Mixed Effect Models for Gene Level Association Studies of Complex Traits |
| Q34177014 | A LASSO-based approach to analyzing rare variants in genetic association studies. |
| Q90484214 | A Rare Variant Nonparametric Linkage Method for Nuclear and Extended Pedigrees with Application to Late-Onset Alzheimer Disease via WGS Data |
| Q37221064 | A biologically informed method for detecting rare variant associations |
| Q34180858 | A comprehensive evaluation of collapsing methods using simulated and real data: excellent annotation of functionality and large sample sizes required |
| Q33983655 | A data-driven method for identifying rare variants with heterogeneous trait effects |
| Q34366963 | A fast and noise-resilient approach to detect rare-variant associations with deep sequencing data for complex disorders. |
| Q34961926 | A flexible approach for the analysis of rare variants allowing for a mixture of effects on binary or quantitative traits |
| Q34100213 | A flexible likelihood framework for detecting associations with secondary phenotypes in genetic studies using selected samples: application to sequence data |
| Q30746271 | A generalized genetic random field method for the genetic association analysis of sequencing data |
| Q64087111 | A generalized model for combining dependent SNP-level summary statistics and its extensions to statistics of other levels |
| Q24625579 | A genome-wide association study of Cloninger's temperament scales: implications for the evolutionary genetics of personality |
| Q37031565 | A geometric framework for evaluating rare variant tests of association |
| Q35117929 | A kernel machine method for detecting effects of interaction between multidimensional variable sets: an imaging genetics application |
| Q34853471 | A linkage disequilibrium-based approach to selecting disease-associated rare variants |
| Q31141263 | A new statistical framework for genetic pleiotropic analysis of high dimensional phenotype data |
| Q33815362 | A new testing strategy to identify rare variants with either risk or protective effect on disease |
| Q47133696 | A non-threshold region-specific method for detecting rare variants in complex diseases. |
| Q35739392 | A novel approach for the simultaneous analysis of common and rare variants in complex traits |
| Q30000847 | A novel genome-information content-based statistic for genome-wide association analysis designed for next-generation sequencing data |
| Q34936804 | A novel support vector machine-based approach for rare variant detection |
| Q34177313 | A pathway-based association analysis model using common and rare variants. |
| Q36152921 | A permutation procedure to correct for confounders in case-control studies, including tests of rare variation |
| Q42263943 | A rapid method for combined analysis of common and rare variants at the level of a region, gene, or pathway |
| Q36379034 | A rare-variant test for high-dimensional data |
| Q35489723 | A review of study designs and statistical methods for genomic epidemiology studies using next generation sequencing |
| Q35072985 | A robust model-free approach for rare variants association studies incorporating gene-gene and gene-environmental interactions |
| Q30502197 | A scan statistic to extract causal gene clusters from case-control genome-wide rare CNV data |
| Q90955290 | A simple and accurate method to determine genomewide significance for association tests in sequencing studies |
| Q35266375 | A statistical approach for rare-variant association testing in affected sibships |
| Q34255618 | A unified framework for detecting rare variant quantitative trait associations in pedigree and unrelated individuals via sequence data |
| Q30578001 | A unified method for detecting secondary trait associations with rare variants: application to sequence data |
| Q37088008 | A unified mixed-effects model for rare-variant association in sequencing studies |
| Q30599570 | A variance component based multi-marker association test using family and unrelated data. |
| Q30578631 | A variational Bayes discrete mixture test for rare variant association |
| Q34176514 | A weighted accumulation test for associating rare genetic variation with quantitative phenotypes |
| Q91785379 | A weighted burden test using logistic regression for integrated analysis of sequence variants, copy number variants and polygenic risk score |
| Q34207166 | ARIEL and AMELIA: testing for an accumulation of rare variants using next-generation sequencing data |
| Q42639822 | Adaptive combination of Bayes factors as a powerful method for the joint analysis of rare and common variants |
| Q30881935 | Adaptive combination of P-values for family-based association testing with sequence data |
| Q34406366 | Adaptive ridge regression for rare variant detection |
| Q41898785 | Adaptive tests for association analysis of rare variants |
| Q34176630 | Addition of multiple rare SNPs to known common variants improves the association between disease and gene in the Genetic Analysis Workshop 17 data |
| Q30846312 | Adjusting family relatedness in data-driven burden test of rare variants |
| Q34277798 | Adrenergic alpha-1 pathway is associated with hypertension among Nigerians in a pathway-focused analysis |
| Q52370685 | Advances in the Genetics of Hypertension: The Effect of Rare Variants. |
| Q41053010 | An application and empirical comparison of statistical analysis methods for associating rare variants to a complex phenotype. |
| Q38840930 | An efficient and flexible test for rare variant effects |
| Q42004381 | An evaluation of different meta-analysis approaches in the presence of allelic heterogeneity |
| Q64890398 | An integrative association method for omics data based on a modified Fisher's method with application to childhood asthma. |
| Q34071259 | Analysis and optimal design for association studies using next-generation sequencing with case-control pools |
| Q30879467 | Analysis of Genetic Analysis Workshop 18 data with gene-based penalized regression |
| Q42796366 | Analysis of rare variant population structure in Europeans explains differential stratification of gene-based tests. |
| Q34672061 | Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls |
| Q36599271 | Annual Research Review: Discovery science strategies in studies of the pathophysiology of child and adolescent psychiatric disorders--promises and limitations |
| Q34177274 | Application of collapsing methods for continuous traits to the Genetic Analysis Workshop 17 exome sequence data |
| Q34175859 | Are quantitative trait-dependent sampling designs cost-effective for analysis of rare and common variants? |
| Q37986775 | Assessing gene-gene interactions in pharmacogenomics |
| Q33841844 | Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression |
| Q33933525 | Assessing the contribution family data can make to case-control studies of rare variants |
| Q34614279 | Assessing the impact of differential genotyping errors on rare variant tests of association |
| Q34175210 | Assessing the impact of missing genotype data in rare variant association analysis |
| Q35546078 | Assessing the impact of non-differential genotyping errors on rare variant tests of association |
| Q39870473 | Assessing the impact of population stratification on association studies of rare variation |
| Q30426205 | Assessment of rare BRCA1 and BRCA2 variants of unknown significance using hierarchical modeling |
| Q36365189 | Associating Multivariate Quantitative Phenotypes with Genetic Variants in Family Samples with a Novel Kernel Machine Regression Method |
| Q35148971 | Association testing of clustered rare causal variants in case-control studies. |
| Q30714713 | BETASEQ: a powerful novel method to control type-I error inflation in partially sequenced data for rare variant association testing |
| Q24618859 | Basic statistical analysis in genetic case-control studies |
| Q35435860 | Bayesian analysis of rare variants in genetic association studies |
| Q51095276 | Bayesian latent variable collapsing model for detecting rare variant interaction effect in twin study. |
| Q36605794 | Beyond Rare-Variant Association Testing: Pinpointing Rare Causal Variants in Case-Control Sequencing Study |
| Q33679037 | Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer |
| Q57822917 | Blindly Using Wald's Test Can Miss Rare Disease-Causal Variants in Case-Control Association Studies |
| Q37509918 | Blocking approach for identification of rare variants in family-based association studies |
| Q37218511 | Boosting the Power of the Sequence Kernel Association Test by Properly Estimating Its Null Distribution |
| Q45158099 | Brief report: high-throughput sequencing of IL23R reveals a low-frequency, nonsynonymous single-nucleotide polymorphism that is associated with ankylosing spondylitis in a Han Chinese population |
| Q33724778 | CCRaVAT and QuTie-enabling analysis of rare variants in large-scale case control and quantitative trait association studies |
| Q35854930 | Case-only exome sequencing and complex disease susceptibility gene discovery: study design considerations |
| Q26853446 | Child development and molecular genetics: 14 years later |
| Q27014915 | Clinical review: Genome-wide association studies of skeletal phenotypes: what we have learned and where we are headed |
| Q34176676 | Collapsing-based and kernel-based single-gene analyses applied to Genetic Analysis Workshop 17 mini-exome data |
| Q57426309 | Common and rare genetic markers of lipid variation in subjects with type 2 diabetes from the ACCORD clinical trial |
| Q34177600 | Comparative study of statistical methods for detecting association with rare variants in exome-resequencing data |
| Q36226036 | Comparing family-based rare variant association tests for dichotomous phenotypes |
| Q34176408 | Comparison of collapsing methods for the statistical analysis of rare variants |
| Q34177548 | Comparison of genetic association strategies in the presence of rare alleles |
| Q36386480 | Comparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits. |
| Q34176182 | Comparison of statistical approaches to rare variant analysis for quantitative traits. |
| Q34388775 | Comparison of statistical tests for association between rare variants and binary traits |
| Q38769458 | Comparison of statistical tests for disease association with rare variants |
| Q27024342 | Computational and statistical approaches to analyzing variants identified by exome sequencing |
| Q42786144 | Confounded by sequencing depth in association studies of rare alleles |
| Q35081395 | Critical assessment of coalescent simulators in modeling recombination hotspots in genomic sequences |
| Q33749328 | Data quality control in genetic case-control association studies. |
| Q58910969 | Design and Statistical Analysis of Pooled Next Generation Sequencing for Rare Variants |
| Q99631535 | Detecting X-linked common and rare variant effects in family-based sequencing studies |
| Q34176764 | Detecting functional rare variants by collapsing and incorporating functional annotation in Genetic Analysis Workshop 17 mini-exome data |
| Q35044206 | Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS). |
| Q42109315 | Detecting rare variant effects using extreme phenotype sampling in sequencing association studies |
| Q35697719 | Detecting the Genomic Signature of Divergent Selection in Presence of Gene Flow |
| Q42054812 | Differential confounding of rare and common variants in spatially structured populations |
| Q34177573 | Digging into the extremes: a useful approach for the analysis of rare variants with continuous traits? |
| Q38843404 | Discovery of rare variants for complex phenotypes. |
| Q34471680 | Dynamic Bayesian testing of sets of variants in complex diseases |
| Q98665271 | Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale |
| Q59353367 | EPHA2 sequence variants are associated with susceptibility to Kaposi's sarcoma-associated herpesvirus infection and Kaposi's sarcoma prevalence in HIV-infected patients |
| Q34176552 | Effect of population stratification analysis on false-positive rates for common and rare variants |
| Q33739535 | Effect of rare variants in ADRB2 on risk of severe exacerbations and symptom control during longacting β agonist treatment in a multiethnic asthma population: a genetic study |
| Q30828110 | Effective filtering strategies to improve data quality from population-based whole exome sequencing studies. |
| Q36769471 | Efficient identification of rare variants in large populations: deep re-sequencing the CRP locus in the CARDIA study. |
| Q36358480 | Estimating genetic effects and quantifying missing heritability explained by identified rare-variant associations |
| Q34177291 | Evaluating methods for combining rare variant data in pathway-based tests of genetic association |
| Q34176920 | Evaluating methods for the analysis of rare variants in sequence data |
| Q51370010 | Evaluating rare variants under two-stage design. |
| Q30879655 | Evaluating the concordance between sequencing, imputation and microarray genotype calls in the GAW18 data. |
| Q37689468 | Evaluating the impact of genotype errors on rare variant tests of association |
| Q34176817 | Evaluation of pooled association tests for rare variant identification. |
| Q36193507 | Examining the overlap between genome-wide rare variant association signals and linkage peaks in rheumatoid arthritis |
| Q37650437 | Exome chip analyses in adult attention deficit hyperactivity disorder. |
| Q27027055 | Exome sequencing and complex disease: practical aspects of rare variant association studies |
| Q29615382 | Exome sequencing as a tool for Mendelian disease gene discovery |
| Q30377611 | Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload. |
| Q30452653 | Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis |
| Q47137829 | Exome-wide study of ankylosing spondylitis demonstrates additional shared genetic background with inflammatory bowel disease |
| Q35182914 | FFBSKAT: fast family-based sequence kernel association test |
| Q30882617 | False discovery rates for rare variants from sequenced data |
| Q61809677 | Family-based association tests for rare variants with censored traits |
| Q30587122 | Family-based association tests for sequence data, and comparisons with population-based association tests |
| Q30418221 | Fine-scale patterns of population stratification confound rare variant association tests |
| Q34068202 | Flexible and robust methods for rare-variant testing of quantitative traits in trios and nuclear families |
| Q89900879 | From exomes to genomes: challenges and solutions in population-based genetic association studies |
| Q34180342 | Functional linear models for association analysis of quantitative traits |
| Q33891719 | GWAS to Sequencing: Divergence in Study Design and Analysis |
| Q36071282 | Gene Level Meta-Analysis of Quantitative Traits by Functional Linear Models |
| Q36494293 | Gene-Based Association Analysis for Censored Traits Via Fixed Effect Functional Regressions |
| Q90014595 | Gene-based association analysis of survival traits via functional regression-based mixed effect cox models for related samples |
| Q31126299 | Gene-set association tests for next-generation sequencing data |
| Q40090917 | Generalization of Rare Variant Association Tests for Longitudinal Family Studies |
| Q34307663 | Generalized functional linear models for gene-based case-control association studies |
| Q40893703 | Genetic Epidemiology and Public Health: The Evolution From Theory to Technology |
| Q36591396 | Genetic association of cyclic AMP signaling genes with bipolar disorder |
| Q38689422 | Genetic association studies in cardiovascular diseases: Do we have enough power? |
| Q49608512 | Genetic modifiers of Mendelian disease: Huntington's disease and the trinucleotide repeat disorders. |
| Q34284362 | Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans. |
| Q24289409 | Genetics of the connectome |
| Q34138007 | Genome-wide approaches to schizophrenia |
| Q41820122 | Genome-wide association analysis of imputed rare variants: application to seven common complex diseases |
| Q47098257 | Genomic determinants of long-term cardiometabolic complications in childhood acute lymphoblastic leukemia survivors |
| Q36117265 | Genotype distribution-based inference of collective effects in genome-wide association studies: insights to age-related macular degeneration disease mechanism. |
| Q36807689 | Group association test using a hidden Markov model |
| Q51737309 | GxGrare: gene-gene interaction analysis method for rare variants from high-throughput sequencing data. |
| Q33976828 | Haplotype kernel association test as a powerful method to identify chromosomal regions harboring uncommon causal variants. |
| Q36441989 | Haplotype-based methods for detecting uncommon causal variants with common SNPs |
| Q34437899 | Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population |
| Q30869613 | Hierarchical Bayesian model for rare variant association analysis integrating genotype uncertainty in human sequence data |
| Q39537322 | Hierarchical generalized linear models for multiple groups of rare and common variants: jointly estimating group and individual-variant effects |
| Q34175946 | Identification of functional rare variants in genome-wide association studies using stability selection based on random collapsing |
| Q41890953 | Identification of grouped rare and common variants via penalized logistic regression |
| Q34414016 | Identification of rare variants in Alzheimer's disease |
| Q64234952 | Identifying individual risk rare variants using protein structure guided local tests (POINT) |
| Q36226155 | Identifying rare and common variants with Bayesian variable selection |
| Q34175438 | Identifying rare disease variants in the Genetic Analysis Workshop 17 simulated data: a comparison of several statistical approaches |
| Q41672988 | Illustrating, Quantifying, and Correcting for Bias in Post-hoc Analysis of Gene-Based Rare Variant Tests of Association |
| Q34176294 | Improved power by collapsing rare and common variants based on a data-adaptive forward selection strategy |
| Q52562215 | Improved score statistics for meta-analysis in single-variant and gene-level association studies. |
| Q38705442 | Improving power for rare-variant tests by integrating external controls |
| Q38274665 | Imputation of rare variants in next-generation association studies |
| Q24618492 | In search of low-frequency and rare variants affecting complex traits |
| Q36069265 | Incorporating Functional Information in Tests of Excess De Novo Mutational Load. |
| Q34212963 | Incorporating gene-environment interaction in testing for association with rare genetic variants |
| Q37606065 | Incorporating model uncertainty in detecting rare variants: the Bayesian risk index |
| Q40132047 | Influence of common and rare genetic variation on warfarin dose among African-Americans and European-Americans using the exome array |
| Q38163845 | Inherited genetic susceptibility to multiple myeloma |
| Q26799138 | Insights into blood lipids from rare variant discovery |
| Q35746734 | Integrating Rare-Variant Testing, Function Prediction, and Gene Network in Composite Resequencing-Based Genome-Wide Association Studies (CR-GWAS). |
| Q36106356 | Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease |
| Q30408390 | Introduction to deep sequencing and its application to drug addiction research with a focus on rare variants |
| Q30277784 | Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer |
| Q47572697 | Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa |
| Q34175931 | Joint association analysis of bivariate quantitative and qualitative traits |
| Q35116305 | Joint association testing of common and rare genetic variants using hierarchical modeling |
| Q36749914 | Joint prediction of multiple quantitative traits using a Bayesian multivariate antedependence model. |
| Q30932501 | Kullback-Leibler distance methods for detecting disease association with rare variants from sequencing data |
| Q53648320 | Leveraging population information in family-based rare variant association analyses of quantitative traits. |
| Q62772008 | Linear mixed models for association analysis of quantitative traits with next-generation sequencing data |
| Q36210698 | Localization of association signal from risk and protective variants in sequencing studies |
| Q39177303 | Longitudinal SNP-set association analysis of quantitative phenotypes |
| Q33677747 | Longitudinal data analysis for rare variants detection with penalized quadratic inference function |
| Q53245195 | Mendelian genes for Parkinson's disease contribute to the sporadic forms of the disease. |
| Q40816303 | Meta-analysis for Discovering Rare-Variant Associations: Statistical Methods and Software Programs |
| Q38105261 | Meta-analysis methods for genome-wide association studies and beyond |
| Q36677259 | Meta-analysis of Complex Diseases at Gene Level with Generalized Functional Linear Models |
| Q37083452 | Meta-analysis of gene-level associations for rare variants based on single-variant statistics |
| Q37610893 | Meta-analysis of gene-level tests for rare variant association |
| Q38779856 | Meta-analysis of quantitative pleiotropic traits for next-generation sequencing with multivariate functional linear models |
| Q34147889 | Meta-analysis of sequencing studies with heterogeneous genetic associations |
| Q63352621 | Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci |
| Q38219242 | Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits |
| Q34175418 | Methods for adjusting population structure and familial relatedness in association test for collective effect of multiple rare variants on quantitative traits |
| Q42585226 | Methods for association analysis and meta-analysis of rare variants in families |
| Q30841933 | Methods for collapsing multiple rare variants in whole-genome sequence data |
| Q29614586 | Missing heritability and strategies for finding the underlying causes of complex disease |
| Q96171658 | Multi-trait analysis of rare-variant association summary statistics using MTAR |
| Q38723253 | Multiancestry Study of Gene-Lifestyle Interactions for Cardiovascular Traits in 610 475 Individuals From 124 Cohorts: Design and Rationale |
| Q30376535 | Mutations Causing Complex Disease May under Certain Circumstances Be Protective in an Epidemiological Sense. |
| Q36594014 | Novel Genetic Loci Associated With Retinal Microvascular Diameter |
| Q34177241 | Novel tree-based method to generate markers from rare variant data |
| Q28731717 | Old lessons learned anew: family-based methods for detecting genes responsible for quantitative and qualitative traits in the Genetic Analysis Workshop 17 mini-exome sequence data |
| Q36600267 | On Efficient and Accurate Calculation of Significance P-Values for Sequence Kernel Association Testing of Variant Set. |
| Q36600244 | On Sample Size and Power Calculation for Variant Set-Based Association Tests |
| Q44928161 | On rare-variant analysis in population-based designs: decomposing the likelihood to two informative components. |
| Q34149953 | On the Aggregation of Multimarker Information for Marker-Set and Sequencing Data Analysis: Genotype Collapsing vs. Similarity Collapsing. |
| Q48345656 | On the substructure controls in rare variant analysis: Principal components or variance components? |
| Q31065241 | Optimal tests for rare variant effects in sequencing association studies |
| Q36152947 | Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies |
| Q30537560 | Optimum designs for next-generation sequencing to discover rare variants for common complex disease |
| Q39084727 | PERCH: A Unified Framework for Disease Gene Prioritization |
| Q48251025 | PLD3 in non-familial Alzheimer's disease |
| Q37376150 | Pathway-based approaches for sequencing-based genome-wide association studies. |
| Q30857114 | Performance of statistical methods on CHARGE targeted sequencing data |
| Q37600573 | Pharmacogenetics: implications of race and ethnicity on defining genetic profiles for personalized medicine |
| Q28647065 | Pleiotropy analysis of quantitative traits at gene level by multivariate functional linear models |
| Q41886407 | Population-based and family-based designs to analyze rare variants in complex diseases |
| Q44112220 | Population-based case-control association studies |
| Q47304007 | Power Analysis for Genetic Association Test (PAGEANT) provides insights to challenges for rare variant association studies |
| Q37646569 | Power of family-based association designs to detect rare variants in large pedigrees using imputed genotypes |
| Q53473853 | Prioritization and burden analysis of rare variants in 208 candidate genes suggest they do not play a major role in CAKUT. |
| Q36226064 | Prioritization of family member sequencing for the detection of rare variants |
| Q34033294 | Prioritizing disease-linked variants, genes, and pathways with an interactive whole-genome analysis pipeline |
| Q38560298 | Prioritizing rare variants with conditional likelihood ratios |
| Q28601645 | Progress in methods for rare variant association |
| Q36495652 | Quantitative trait locus analysis for next-generation sequencing with the functional linear models. |
| Q35863128 | Rapid and robust resampling-based multiple-testing correction with application in a genome-wide expression quantitative trait loci study |
| Q33833360 | Rare LPL gene variants attenuate triglyceride reduction and HDL cholesterol increase in response to fenofibric acid therapy in individuals with mixed dyslipidemia |
| Q37806780 | Rare Variant Association Analysis Methods for Complex Traits |
| Q92685359 | Rare and Low-Frequency Variants in RNF213 Confer Susceptibility to Moyamoya Syndrome Associated with Hyperthyroidism |
| Q28607764 | Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF |
| Q37484322 | Rare variant association testing by adaptive combination of P-values |
| Q30617836 | Rare variant association testing for next-generation sequencing data via hierarchical clustering |
| Q40983057 | Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project |
| Q34176144 | Rare variant collapsing in conjunction with mean log p-value and gradient boosting approaches applied to Genetic Analysis Workshop 17 data |
| Q34175953 | Rare variant density across the genome and across populations |
| Q40133735 | Rare variant testing across methods and thresholds using the multi-kernel sequence kernel association test (MK-SKAT). |
| Q42369215 | Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis |
| Q36524770 | Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis |
| Q31094385 | Rare-Variant Kernel Machine Test for Longitudinal Data from Population and Family Samples |
| Q26852733 | Rare-variant association analysis: study designs and statistical tests |
| Q33954046 | Rare-variant association testing for sequencing data with the sequence kernel association test |
| Q90663950 | Rare-variant collapsing analyses for complex traits: guidelines and applications |
| Q30721849 | Rare-variant extensions of the transmission disequilibrium test: application to autism exome sequence data |
| Q34169930 | Reconsidering association testing methods using single-variant test statistics as alternatives to pooling tests for sequence data with rare variants |
| Q30976711 | Region-Based Association Test for Familial Data under Functional Linear Models |
| Q31120147 | Region-based association analysis of human quantitative traits in related individuals |
| Q36392512 | Region-based association tests for sequencing data on survival traits |
| Q34086452 | Regression and data mining methods for analyses of multiple rare variants in the Genetic Analysis Workshop 17 mini-exome data |
| Q34381743 | Replication strategies for rare variant complex trait association studies via next-generation sequencing |
| Q53392505 | Reproducible simulations of realistic samples for next-generation sequencing studies using Variant Simulation Tools. |
| Q87405700 | Robust and powerful tests for rare variants using Fisher's method to combine evidence of association from two or more complementary tests |
| Q37018622 | SBERIA: set-based gene-environment interaction test for rare and common variants in complex diseases |
| Q34255847 | SEQCHIP: a powerful method to integrate sequence and genotype data for the detection of rare variant associations |
| Q38697963 | SEQSpark: A Complete Analysis Tool for Large-Scale Rare Variant Association Studies Using Whole-Genome and Exome Sequence Data |
| Q30661200 | Secondary analysis of publicly available data reveals superoxide and oxygen radical pathways are enriched for associations between type 2 diabetes and low-frequency variants |
| Q37076975 | Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants |
| Q89581647 | Sequence Analysis of Drug Target Genes with Suicidal Behavior in Bipolar Disorder Patients |
| Q35982039 | Sequence Kernel Association Analysis of Rare Variant Set Based on the Marginal Regression Model for Binary Traits |
| Q36494204 | Sequence Kernel Association Test of Multiple Continuous Phenotypes |
| Q36812083 | Sequence kernel association test for quantitative traits in family samples |
| Q34154446 | Sequence kernel association test for survival traits. |
| Q36148111 | Set-based tests for genetic association in longitudinal studies |
| Q36161327 | Simultaneous Analysis of Common and Rare Variants in Complex Traits: Application to SNPs (SCARVAsnp) |
| Q47661071 | Single Marker Family-Based Association Analysis Conditional on Parental Information |
| Q34085632 | Small sample properties of rare variant analysis methods |
| Q37856462 | Statistical analysis of genetic interactions |
| Q35752081 | Statistical analysis of rare sequence variants: an overview of collapsing methods |
| Q37799723 | Statistical analysis strategies for association studies involving rare variants |
| Q34163502 | Statistical guidance for experimental design and data analysis of mutation detection in rare monogenic mendelian diseases by exome sequencing |
| Q28081028 | Strategies for Imputing and Analyzing Rare Variants in Association Studies |
| Q35542036 | Study designs for identification of rare disease variants in complex diseases: the utility of family-based designs |
| Q37784094 | Synthetic associations in the context of genome-wide association scan signals |
| Q33858791 | Targeted resequencing and systematic in vivo functional testing identifies rare variants in MEIS1 as significant contributors to restless legs syndrome |
| Q36522128 | Test for rare variants by environment interactions in sequencing association studies |
| Q51415298 | Testing cross-phenotype effects of rare variants in longitudinal studies of complex traits. |
| Q30645712 | Testing for rare variant associations in the presence of missing data |
| Q30841941 | Testing genetic association with rare and common variants in family data |
| Q37820686 | The effect of next-generation sequencing technology on complex trait research |
| Q40998328 | The effect of phenotypic outliers and non-normality on rare-variant association testing |
| Q38006632 | The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare variants |
| Q34154481 | The empirical power of rare variant association methods: results from sanger sequencing in 1,998 individuals |
| Q37667627 | The future of genomics for developmentalists |
| Q52145849 | The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis. |
| Q60046260 | The impact of a fine-scale population stratification on rare variant association test results |
| Q33613854 | The impact of rare and low-frequency genetic variants in common disease |
| Q35676416 | The influence of genetics on response to treatment with ranibizumab (Lucentis) for age-related macular degeneration: the Lucentis Genotype Study (an American Ophthalmological Society thesis). |
| Q33354240 | The next generation of complex lung genetic studies |
| Q38137080 | The role and challenges of exome sequencing in studies of human diseases |
| Q30909399 | The role of rare variants in systolic blood pressure: analysis of ExomeChip data in HyperGEN African Americans |
| Q42369086 | To Identify Associations with Rare Variants, Just WHaIT: Weighted Haplotype and Imputation-Based Tests |
| Q33960019 | Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia |
| Q47966894 | Two-phase stratified sampling designs for regional sequencing |
| Q34175504 | Two-stage analyses of sequence variants in association with quantitative traits |
| Q34177177 | Two-stage study designs combining genome-wide association studies, tag single-nucleotide polymorphisms, and exome sequencing: accuracy of genetic effect estimates |
| Q34175677 | Use of Bayesian networks to dissect the complexity of genetic disease: application to the Genetic Analysis Workshop 17 simulated data |
| Q30813514 | Variant association tools for quality control and analysis of large-scale sequence and genotyping array data |
| Q47198423 | Weighted functional linear regression models for gene-based association analysis. |
| Q34151873 | Weighted selective collapsing strategy for detecting rare and common variants in genetic association study |
| Q30879612 | Whole genome sequence analysis of the simulated systolic blood pressure in Genetic Analysis Workshop 18 family data: long-term average and collapsing methods |
| Q45812682 | Whole genome sequencing of extreme phenotypes identifies variants in CD101 and UBE2V1 associated with increased risk of sexually acquired HIV-1. |
| Q34497678 | Whole-genome sequencing of the world's oldest people |