| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2010PLoSO...512606R |
| P356 | DOI | 10.1371/JOURNAL.PONE.0012606 |
| P932 | PMC publication ID | 2935374 |
| P698 | PubMed publication ID | 20830300 |
| P5875 | ResearchGate publication ID | 46192326 |
| P2093 | author name string | Darrell W Brann | |
| Fang Yang | |||
| Dong Han | |||
| Quan-Guang Zhang | |||
| Cai-feng Zhou | |||
| Li-cai Yang | |||
| Rui-min Wang | |||
| Limor Raz | |||
| Priya Gulati | |||
| P2860 | cites work | Targeted inhibition of the small GTPase protects against ischemia/reperfusion liver injury in mice | Q64379991 |
| Peroxynitrite diminishes myogenic tone in cerebral arteries: role of nitrotyrosine and F-actin | Q79240361 | ||
| The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology | Q27860991 | ||
| Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidase | Q28609613 | ||
| Rational design and characterization of a Rac GTPase-specific small molecule inhibitor | Q29616494 | ||
| Developments of a water-maze procedure for studying spatial learning in the rat | Q29617561 | ||
| Spatial deficits in a virtual water maze in amnesic participants with hippocampal damage | Q33474435 | ||
| Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus | Q33580146 | ||
| Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation | Q33595388 | ||
| Temporal profile of neuronal damage in a model of transient forebrain ischemia | Q34278838 | ||
| Reperfusion damage following focal ischemia: pathophysiology and therapeutic windows. | Q34740902 | ||
| Current molecular models for NADPH oxidase regulation by Rac GTPase | Q34915029 | ||
| Glucose and NADPH oxidase drive neuronal superoxide formation in stroke. | Q35006967 | ||
| Tamoxifen neuroprotection in cerebral ischemia involves attenuation of kinase activation and superoxide production and potentiation of mitochondrial superoxide dismutase | Q36372549 | ||
| Mitochondria: a target for neuroprotective interventions in cerebral ischemia-reperfusion | Q36393655 | ||
| Role of the small GTPase Rac in p22phox-dependent NADPH oxidases | Q36855140 | ||
| Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation | Q37091609 | ||
| Rac1 is a critical mediator of endothelium-derived neurotrophic activity | Q37157708 | ||
| Depleting Rac1 in mouse rod photoreceptors protects them from photo-oxidative stress without affecting their structure or function | Q37199959 | ||
| Role of Rac1 GTPase in JNK signaling and delayed neuronal cell death following global cerebral ischemia | Q37241059 | ||
| Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion | Q37322537 | ||
| A new model of bilateral hemispheric ischemia in the unanesthetized rat | Q39259932 | ||
| Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine | Q39428776 | ||
| Apocynin improves outcome in experimental stroke with a narrow dose range | Q42403010 | ||
| c-Jun N-terminal kinase activation in hippocampal CA1 region was involved in ischemic injury | Q43575933 | ||
| Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice. | Q43726340 | ||
| NADPH oxidase immunoreactivity in the mouse brain | Q44602831 | ||
| Neuronal expression of the NADPH oxidase NOX4, and its regulation in mouse experimental brain ischemia | Q46414453 | ||
| NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke | Q46966136 | ||
| Reactive oxygen species plasmatic levels in ischemic stroke | Q48223426 | ||
| Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation. | Q48291254 | ||
| Akt inhibits MLK3/JNK3 signaling by inactivating Rac1: a protective mechanism against ischemic brain injury. | Q48475438 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cerebral infarction | Q1209150 |
| cognitive dysfunction | Q57859955 | ||
| P304 | page(s) | e12606 | |
| P577 | publication date | 2010-09-07 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat | |
| P478 | volume | 5 |
| Q46957674 | 15-Deoxy-∆12,14-PGJ 2, by activating peroxisome proliferator-activated receptor-gamma, suppresses p22phox transcription to protect brain endothelial cells against hypoxia-induced apoptosis |
| Q48317071 | 4-hydroxy-3-methoxy-acetophenone-mediated long-lasting memory recovery, hippocampal neuroprotection, and reduction of glial cell activation after transient global cerebral ischemia in rats. |
| Q48225751 | A Case-Control Study of the Genetic Variability in Reactive Oxygen Species-Metabolizing Enzymes in Melanoma Risk. |
| Q46256199 | A Mini-Review of the NADPH oxidases in Vascular Dementia: Correlation with NOXs and Risk Factors for VaD. |
| Q42156654 | A non-ionotropic activity of NMDA receptors contributes to glycine-induced neuroprotection in cerebral ischemia-reperfusion injury |
| Q27314528 | Acetylation of the pro-apoptotic factor, p53 in the hippocampus following cerebral ischemia and modulation by estrogen |
| Q35846785 | Astroglial NF-κB mediates oxidative stress by regulation of NADPH oxidase in a model of retinal ischemia reperfusion injury. |
| Q46575226 | Atorvastatin improves renal organic anion transporter 3 and renal function in gentamicin-induced nephrotoxicity in rats. |
| Q42729199 | Blockage of NOX2/MAPK/NF-κB Pathway Protects Photoreceptors against Glucose Deprivation-Induced Cell Death |
| Q26751153 | Cerebral Small Vessel Disease: Targeting Oxidative Stress as a Novel Therapeutic Strategy? |
| Q34224919 | Critical role of NADPH oxidase in neuronal oxidative damage and microglia activation following traumatic brain injury |
| Q26771363 | Detrimental or beneficial: the role of TRPM2 in ischemia/reperfusion injury |
| Q39169261 | Diabetic aggravation of stroke and animal models. |
| Q34727327 | Differential Tiam1/Rac1 activation in hippocampal and cortical neurons mediates differential spine shrinkage in response to oxygen/glucose deprivation. |
| Q47094875 | Differential regulation of the Rac1 GTPase-activating protein (GAP) BCR during oxygen/glucose deprivation in hippocampal and cortical neurons |
| Q91864300 | Effects of CXCR7-neutralizing antibody on neurogenesis in the hippocampal dentate gyrus and cognitive function in the chronic phase of cerebral ischemia |
| Q37280921 | Electroacupuncture Ameliorates Learning and Memory via Activation of the CREB Signaling Pathway in the Hippocampus to Attenuate Apoptosis after Cerebral Hypoperfusion |
| Q26861119 | Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement |
| Q48106808 | Genistein attenuates ischemic oxidative damage and behavioral deficits via eNOS/Nrf2/HO-1 signaling |
| Q30539131 | Hypersensitivity of the hippocampal CA3 region to stress-induced neurodegeneration and amyloidogenesis in a rat model of surgical menopause |
| Q27937783 | Identification of Dck1 and Lmo1 as upstream regulators of the small GTPase Rho5 in Saccharomyces cerevisiae |
| Q58610285 | Identification of novel regulatory partners of the glutamate transporter GLT-1 |
| Q48403770 | Influence of acupuncture on cognitive function and markers of oxidative DNA damage in patients with vascular dementia. |
| Q41814054 | Inhibiting NADPH oxidase protects against long-term memory impairment induced by neonatal sevoflurane exposure in mice. |
| Q33916216 | Intermittent hypoxia-induced cognitive deficits are mediated by NADPH oxidase activity in a murine model of sleep apnea |
| Q34625542 | Long-term post-stroke changes include myelin loss, specific deficits in sensory and motor behaviors and complex cognitive impairment detected using active place avoidance |
| Q84272616 | Mechanisms regulating superoxide generation in experimental models of phenylketonuria: an essential role of NADPH oxidase |
| Q35142700 | Minocycline upregulates cyclic AMP response element binding protein and brain-derived neurotrophic factor in the hippocampus of cerebral ischemia rats and improves behavioral deficits |
| Q26820813 | Modulation of actin dynamics by Rac1 to target cognitive function |
| Q37589114 | NADPH oxidase in brain injury and neurodegenerative disorders |
| Q34802636 | NADPH oxidase-2: linking glucose, acidosis, and excitotoxicity in stroke |
| Q84781338 | NADPH oxidase-dependent oxidative stress and mitochondrial damage in hippocampus of D-galactose-induced aging rats |
| Q38012354 | NADPH oxidases as therapeutic targets in ischemic stroke. |
| Q47727115 | Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke. |
| Q48092764 | Neuroprotective Effect and Mechanism of Action of Tetramethylpyrazine Nitrone for Ischemic Stroke Therapy |
| Q41653809 | Neuroprotective and Functional Improvement Effects of Methylene Blue in Global Cerebral Ischemia |
| Q27339265 | Non-muscle myosin II regulates neuronal actin dynamics by interacting with guanine nucleotide exchange factors |
| Q35882885 | Oestrogen signalling and neuroprotection in cerebral ischaemia |
| Q38192646 | Oxidative stress-mediated effects of angiotensin II in the cardiovascular system |
| Q64080455 | Proinsulin C-Peptide Enhances Cell Survival and Protects against Simvastatin-Induced Myotoxicity in L6 Rat Myoblasts |
| Q37644408 | Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia |
| Q42609911 | Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation. |
| Q33677789 | Recombinant Slit2 Reduces Surgical Brain Injury Induced Blood Brain Barrier Disruption via Robo4 Dependent Rac1 Activation in a Rodent Model. |
| Q27027490 | Rho family GTPases: key players in neuronal development, neuronal survival, and neurodegeneration |
| Q37599366 | Rotenone induces neurotoxicity through Rac1-dependent activation of NADPH oxidase in SHSY-5Y cells |
| Q48466663 | Senegenin Inhibits Hypoxia/Reoxygenation-Induced Neuronal Apoptosis by Upregulating RhoGDIα. |
| Q90104763 | Suppression of Cerebral Ischemia/Reperfusion Injury by Efficient Release of Encapsulated Ifenprodil From Liposomes Under Weakly Acidic pH Conditions |
| Q42080051 | TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1. |
| Q38009736 | Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors |
| Q46522841 | Tetramethylpyrazine Protects Against Oxygen-Glucose Deprivation-Induced Brain Microvascular Endothelial Cells Injury via Rho/Rho-kinase Signaling Pathway |
| Q38176761 | The E. coli CNF1 as a pioneering therapy for the central nervous system diseases |
| Q34345666 | The Rac1 inhibitor NSC23766 suppresses CREB signaling by targeting NMDA receptor function. |
| Q60923965 | The Role of NADPH Oxidases and Oxidative Stress in Neurodegenerative Disorders |
| Q26795415 | The Role of Oxidative Damage in the Pathogenesis and Progression of Alzheimer's Disease and Vascular Dementia |
| Q48347207 | The Ubiquitin E3 Ligase TRAF6 Exacerbates Ischemic Stroke by Ubiquitinating and Activating Rac1. |
| Q41819831 | Treatment with Actovegin improves spatial learning and memory in rats following transient forebrain ischaemia |
| Q36745089 | Treatment with Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke, but not brain injury in mice |
| Q38032754 | Vascular cognitive impairment and Alzheimer's disease: role of cerebral hypoperfusion and oxidative stress |
| Q36702523 | Which NADPH oxidase isoform is relevant for ischemic stroke? The case for nox 2. |
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