Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84.

scientific article

Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.IMMUNI.2010.01.010
P932PMC publication ID2830297
P698PubMed publication ID20153220
P5875ResearchGate publication ID41427626

P50authorRonald N. GermainQ62712996
P2093author name stringJun Cheng
Pamela L Schwartzberg
Edward K Wakeland
Hai Qi
Jennifer L Cannons
Julio Gomez-Rodriguez
Kristina T Lu
Mala Dutta
P2860cites workTec kinases regulate TCR-mediated recruitment of signaling molecules and integrin-dependent cell adhesionQ46763999
Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functionsQ47800852
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.Q50736370
SAP regulation of follicular helper CD4 T cell development and humoral immunity is independent of SLAM and Fyn kinase.Q53579591
Requirement of Rac1 and Rac2 Expression by Mature Dendritic Cells for T Cell PrimingQ58862030
The dendritic cell cytoskeleton is critical for the formation of the immunological synapseQ73400715
Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulationQ24292211
Disease-causing SAP mutants are defective in ligand binding and protein foldingQ24301833
Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activationQ24317021
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineagesQ24642180
Follicular helper T cells: lineage and locationQ24647274
Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cellsQ24796689
Structure of CD84 provides insight into SLAM family functionQ27645635
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiationQ28252247
Bcl6 mediates the development of T follicular helper cellsQ28252825
Platelet aggregation induces platelet aggregate stability via SLAM family receptor signalingQ28263181
T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cellsQ28268047
A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunityQ28507088
Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage developmentQ28584820
SAP is required for generating long-term humoral immunityQ28588045
Molecular dissection of 2B4 signaling: implications for signal transduction by SLAM-related receptorsQ34345732
NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor familyQ34574420
Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules.Q34597428
T-cell receptor signaling to integrinsQ34648944
The SLAM and SAP gene families control innate and adaptive immune responses.Q34781617
SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulationQ36228622
Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAPQ36310561
Vav1 phosphorylation is induced by beta2 integrin engagement on natural killer cells upstream of actin cytoskeleton and lipid raft reorganization.Q36371393
The cell surface receptor SLAM controls T cell and macrophage functionsQ36399495
Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells.Q36403556
Germinal-center organization and cellular dynamicsQ36459345
The role of SAP and the SLAM family in autoimmunityQ36608572
SAP-controlled T-B cell interactions underlie germinal centre formationQ37119530
Follicular helper T cells are required for systemic autoimmunityQ37234304
SLAM receptors and SAP influence lymphocyte interactions, development and functionQ37349689
Development and characterization of IL-21-producing CD4+ T cellsQ38845667
Control of T lymphocyte signaling by Ly108, a signaling lymphocytic activation molecule family receptor implicated in autoimmunityQ39981953
Improved generation of C57BL/6J mouse embryonic stem cells in a defined serum-free mediaQ40550540
Coexpression of CD58 or CD48 with intercellular adhesion molecule 1 on target cells enhances adhesion of resting NK cells.Q40681821
Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupusQ45180946
Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation.Q46006953
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcell adhesionQ187640
P304page(s)253-265
P577publication date2010-02-11
P1433published inImmunityQ6005457
P1476titleOptimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84.
P478volume32

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