Studies on Taxol® Biosynthesis. Preparation and Tritium Labeling of Biosynthetic intermediates by Deoxygenation of a Taxadiene Tetra-acetate Obtained from Japanese Yew.

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Studies on Taxol® Biosynthesis. Preparation and Tritium Labeling of Biosynthetic intermediates by Deoxygenation of a Taxadiene Tetra-acetate Obtained from Japanese Yew. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JLCR.1529
P932PMC publication ID2835351
P698PubMed publication ID20221307
P5875ResearchGate publication ID41895989

P2093author name stringRodney Croteau
Robert M Williams
Christopher D Rithner
Tohru Horiguchi
P2860cites workTaxol biosynthesis: taxane 13 alpha-hydroxylase is a cytochrome P450-dependent monooxygenaseQ24555092
Intramolecular proton transfer in the cyclization of geranylgeranyl diphosphate to the taxadiene precursor of taxol catalyzed by recombinant taxadiene synthaseQ28141590
Mechanism of taxadiene synthase, a diterpene cyclase that catalyzes the first step of taxol biosynthesis in Pacific yewQ28276543
Cytochrome P450-catalyzed hydroxylation of taxa-4(5),11(12)-diene to taxa-4(20),11(12)-dien-5alpha-ol: the first oxygenation step in taxol biosynthesisQ28289878
Purification and characterization of taxa-4(5),11(12)-diene synthase from Pacific yew (Taxus brevifolia) that catalyzes the first committed step of taxol biosynthesisQ28290316
Cyclization of geranylgeranyl diphosphate to taxa-4(5),11(12)-diene is the committed step of taxol biosynthesis in Pacific yewQ28300152
Molecular cloning of a taxa-4(20),11(12)-dien-5alpha-ol-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coliQ30837740
Cytochrome P450 oxygenases of Taxol biosynthesisQ30985560
Taxol biosynthetic genesQ31004828
Partial purification and characterization of acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase that catalyzes the first acylation step of taxol biosynthesisQ33857714
Induction of the sexual stage of Pestalotiopsis microspora, a taxol-producing fungusQ33912775
Molecular cloning of a cytochrome P450 taxane 10 beta-hydroxylase cDNA from Taxus and functional expression in yeastQ34085514
Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifoliaQ34235776
Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific yew.Q34334768
Administering cultured Taxus cells with early precursors reveals bifurcations in the taxoid biosynthetic pathwayQ36015856
Taxol biosynthesis: an updateQ38556559
Stable transformation and long-term maintenance of transgenic Taxus cell suspension culturesQ40164254
Clinical overview of the taxanes.Q41606989
Studies on taxol biosynthesis. Preparation of taxa-4(20),11(12)-dien-5 alpha-acetoxy-10 beta-ol by deoxygenation of a taxadiene tetraacetate obtained from Japanese yew.Q44050595
P433issue9
P304page(s)325-328
P577publication date2008-08-01
P1433published inJournal of Labelled Compounds and RadiopharmaceuticalsQ3186923
P1476titleStudies on Taxol® Biosynthesis. Preparation and Tritium Labeling of Biosynthetic intermediates by Deoxygenation of a Taxadiene Tetra-acetate Obtained from Japanese Yew.
P478volume51

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cites work (P2860)
Q35850515Identification of the Key Fields and Their Key Technical Points of Oncology by Patent Analysis
Q35215703Natural products synthesis: enabling tools to penetrate Nature's secrets of biogenesis and biomechanism
Q36027443The early stages of taxol biosynthesis: an interim report on the synthesis and identification of early pathway metabolites

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