Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy study

scientific article

Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy study is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/CVR/CVP396
P932PMC publication ID2836261
P698PubMed publication ID20008827
P5875ResearchGate publication ID40686549

P50authorGeorge K. RaddaQ5543683
Damian J. TylerQ42108873
Ferdia A GallagherQ57192026
Pawel SwietachQ63385875
P2093author name stringKieran Clarke
Phillip Lee
Marie A Schroeder
Helen J Atherton
P2860cites workIncrease in signal-to-noise ratio of > 10,000 times in liquid-state NMRQ24683340
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Observation of tissue metabolites using 31P nuclear magnetic resonanceQ34210039
Dynamic Nuclear Polarization of [1-13C]pyruvic acid at 4.6 teslaQ34927729
Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR.Q36288856
Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusionQ36702426
Regulation of tumor pH and the role of carbonic anhydrase 9.Q36784373
In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonanceQ36835334
Inhibition of carbohydrate oxidation during the first minute of reperfusion after brief ischemia: NMR detection of hyperpolarized 13CO2 and H13CO3-.Q37228743
Intracellular pH regulation in heart.Q37337546
Myocardial ischemia--metabolic pathways and implications of increased glycolysisQ37572588
Studies of acidosis in the ischaemic heart by phosphorus nuclear magnetic resonanceQ39302252
Regulation of intracellular pH in eukaryotic cellsQ39485522
Methods of measuring intracellular pH in the heartQ40517094
Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.Q42062389
Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI.Q42169319
Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte.Q46142288
Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonateQ46570233
Activity of phosphorylase in total global ischaemia in the rat heart A phosphorus-31 nuclear-magnetic-resonance studyQ46590642
Insulin resistance, abnormal energy metabolism and increased ischemic damage in the chronically infarcted rat heart.Q51499918
Pyruvate dehydrogenase activity and malonyl CoA levels in normal and ischemic swine myocardium: effects of dichloroacetate.Q53987970
31P NMR measurements of myocardial pH invivoQ64004806
Intracellular pH and inorganic phosphate content of heart in vivo: a 31P-NMR studyQ68445152
Glucose and palmitate oxidation in isolated working rat hearts reperfused after a period of transient global ischemiaQ68697945
Heart Muscle Viability following Hypoxia: Protective Effect of AcidosisQ69528714
The rates of fast reactions of carbon dioxide and bicarbonate in human erythrocytes measured by carbon-13 NMRQ70330700
Is lactate-induced myocardial ischaemic injury mediated by decreased pH or increased intracellular lactate?Q71514766
Effects of ischemia and reperfusion on pyruvate dehydrogenase activity in isolated rat heartsQ71800191
Carbonic anhydrase and cardiac pH regulationQ71977984
Pyruvate dehydrogenase influences postischemic heart functionQ72642260
Mechanisms of pHi recovery after global ischemia in the perfused heartQ72966295
Out-of-equilibrium pH transients in the guinea-pig ventricular myocyteQ74517057
THE PH-ACTIVITY CURVE OF BOVINE CARBONIC ANHYDRASE AND ITS RELATIONSHIP TO THE INHIBITION OF THE ENZYME BY ANIONSQ78384294
Carbonic anhydrase inhibition prevents and reverts cardiomyocyte hypertrophyQ79379610
P433issue1
P921main subjectspectroscopyQ483666
P304page(s)82-91
P577publication date2009-12-15
P1433published inCardiovascular ResearchQ4642329
P1476titleMeasuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy study
P478volume86

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