Tissue transglutaminase contributes to the pathogenesis of preeclampsia and stabilizes placental angiotensin receptor type 1 by ubiquitination-preventing isopeptide modification

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Tissue transglutaminase contributes to the pathogenesis of preeclampsia and stabilizes placental angiotensin receptor type 1 by ubiquitination-preventing isopeptide modification is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/HYPERTENSIONAHA.113.02361
P932PMC publication ID4052572
P698PubMed publication ID24191290
P5875ResearchGate publication ID258282754

P50authorBaha SibaiQ100559638
P2093author name stringWei Wang
Yang Xia
Chen Liu
Rodney E Kellems
Jianping Jin
Nicholas Parchim
Roxanna A Irani
Sean C Blackwell
P2860cites workSerotonylation of vascular proteins important to contractionQ21562428
Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminaseQ24548047
Soluble endoglin contributes to the pathogenesis of preeclampsiaQ28244053
Protein transamidation by transglutaminase 2 in cells: a disputed Ca2+-dependent action of a multifunctional proteinQ28247511
Involvement of tissue transglutaminase in endothelin 1-induced hypertrophy in cultured neonatal rat cardiomyocytesQ28576560
Gh: a GTP-binding protein with transglutaminase activity and receptor signaling functionQ28578829
Factor XIIIA transglutaminase crosslinks AT1 receptor dimers of monocytes at the onset of atherosclerosisQ28589061
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells.Q30441613
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
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Transglutaminase 2: a molecular Swiss army knifeQ35693361
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant miceQ35701236
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Recent progress toward the understanding of the pathophysiology of hypertension during preeclampsiaQ37079628
Inflammatory cytokines in the pathophysiology of hypertension during preeclampsiaQ37119326
Cellular localization of AT1 receptor mRNA and protein in normal placenta and its reduced expression in intrauterine growth restriction. Angiotensin II stimulates the release of vasorelaxantsQ37377636
Transglutaminase-mediated intramolecular cross-linking of membrane-bound alpha-synuclein promotes amyloid formation in Lewy bodies.Q37447970
The role of hypoxia and hypoxia-inducible factor-1alpha in preeclampsia pathogenesisQ38049205
Differential signaling by the thromboxane receptor isoforms via the novel GTP-binding protein, Gh.Q38325669
TNF-alpha modulates expression of the tissue transglutaminase gene in liver cellsQ38339721
Increased tissue transglutaminase expression in human atherosclerotic coronary arteriesQ39928833
Tissue transglutaminase expression and activity in placenta.Q40341880
Oxytocin receptor couples to the 80 kDa Gh alpha family protein in human myometrium.Q42160198
Modulation of the in situ activity of tissue transglutaminase by calcium and GTP.Q42449902
ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome that commit to degradationQ42600957
Changes in the metabolic footprint of placental explant-conditioned culture medium identifies metabolic disturbances related to hypoxia and pre-eclampsia.Q43272404
Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamineQ43873037
Therapeutic effects of cystamine in a murine model of Huntington's disease.Q44185981
Tissue transglutaminase catalyzes the formation of alpha-synuclein crosslinks in Parkinson's diseaseQ44786885
Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activationQ45069619
Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregationQ45077697
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of interleukin 6.Q51139503
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of tumor necrosis factor-alpha.Q51359651
Developmental regulation of tissue transglutaminase during human placentation and expression in neoplastic trophoblast.Q52197515
A role for tissue transglutaminase in stabilization of membrane-cytoskeletal particles shed from the human placenta.Q53541406
Prevalence of agonistic autoantibodies against the angiotensin II type 1 receptor and soluble fms-like tyrosine kinase 1 in a gestational age-matched case study.Q54782424
Differential expression of angiotensin II type 1 and type 2 receptors at the maternal–fetal interface: potential roles in early placental developmentQ61866802
The binding of divalent metal ions to platelet factor XIII modulates its proteolysis by trypsin and thrombin.Q64917428
Expression induced by interleukin-6 of tissue-type transglutaminase in human hepatoblastoma HepG2 cellsQ72214769
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
Effect of cystamine on blood pressure and vascular characteristics in spontaneously hypertensive ratsQ84583188
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectpre-eclampsiaQ61335
pathogenesisQ372016
protein ubiquitinationQ3547638
P304page(s)353-361
P577publication date2013-11-04
P1433published inHypertensionQ5958695
P1476titleTissue transglutaminase contributes to the pathogenesis of preeclampsia and stabilizes placental angiotensin receptor type 1 by ubiquitination-preventing isopeptide modification
P478volume63

Reverse relations

cites work (P2860)
Q89006965Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology
Q107324240Autoantibodies against ACE2 and angiotensin type-1 receptors increase severity of COVID-19
Q36339273Blockade of CD40 ligand for intercellular communication reduces hypertension, placental oxidative stress, and AT1-AA in response to adoptive transfer of CD4+ T lymphocytes from RUPP rats
Q34473794Cystamine preparations exhibit anticoagulant activity
Q36836373Elevated Transglutaminase Activity Triggers Angiotensin Receptor Activating Autoantibody Production and Pathophysiology of Preeclampsia
Q39198610Inflammation, Autoimmunity, and Hypertension: The Essential Role of Tissue Transglutaminase
Q36599656Involvement of transglutaminase 2 and voltage-gated potassium channels in cystamine vasodilatation in rat mesenteric small arteries.
Q36584747Preeclampsia and Pregnancy-Related Hypertensive Disorders
Q39166559Protein Phosphotyrosine Phosphatase 1B (PTP1B) in Calpain-dependent Feedback Regulation of Vascular Endothelial Growth Factor Receptor (VEGFR2) in Endothelial Cells: IMPLICATIONS IN VEGF-DEPENDENT ANGIOGENESIS AND DIABETIC WOUND HEALING.
Q55259961Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension.
Q46308477The relationship between circulating tissue transglutaminase, soluble fms-like tyrosine kinase-1, soluble endoglin and vascular endothelial growth factor in pre-eclampsia
Q64233038Tissue Transglutaminase-Mediated AT1 Receptor Sensitization Underlies Pro-inflammatory Cytokine LIGHT-Induced Hypertension
Q41521275Transglutaminase 2 in human diseases
Q37240779Transglutaminase is a Critical Link Between Inflammation and Hypertension

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