review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1007/S11906-007-0088-1 |
P698 | PubMed publication ID | 18367011 |
P2093 | author name string | Jeffrey S Gilbert | |
Michael J Ryan | |||
Joey P Granger | |||
Sydney R Murphy | |||
Babbette D LaMarca | |||
P2860 | cites work | Soluble Fms-like tyrosine kinase 1 and endothelial dysfunction in the pathogenesis of preeclampsia | Q28244090 |
Cardiovascular and renal sympathetic activation by blood-borne TNF-alpha in rat: the role of central prostaglandins | Q28581223 | ||
Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy | Q35699115 | ||
Hypoxia and sFlt-1 in preeclampsia: the "chicken-and-egg" question | Q35920602 | ||
Abnormal placentation and the syndrome of preeclampsia | Q35941005 | ||
Angiogenic imbalance in the pathophysiology of preeclampsia: newer insights | Q35941009 | ||
Preeclampsia: a renal perspective | Q36120940 | ||
Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction | Q36228832 | ||
Neurovascular mechanisms of hypertension in pregnancy | Q36486193 | ||
Endothelial dysfunction in pre-eclampsia. | Q36749162 | ||
Interleukin-1beta and neurogenic control of blood pressure in normal rats and rats with chronic renal failure | Q43495878 | ||
Downregulation of neuronal nitric oxide synthase and interleukin-1beta mediates angiotensin II-dependent stimulation of sympathetic nerve activity | Q43908241 | ||
Enhanced endothelin synthesis by endothelial cells exposed to sera from pregnant rats with decreased uterine perfusion | Q46877931 | ||
Circulating angiogenic factors and the risk of preeclampsia | Q47217679 | ||
Protective effect of vascular endothelial growth factor/vascular permeability factor 165 and 121 on glomerular endothelial cell injury in the rat. | Q47349254 | ||
Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women | Q47770771 | ||
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of interleukin 6. | Q51139503 | ||
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of tumor necrosis factor-alpha. | Q51359651 | ||
GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice. | Q51569218 | ||
Transient local overexpression of human vascular endothelial growth factor (VEGF) in mouse feto-maternal interface during mid-term pregnancy lowers systemic maternal blood pressure. | Q52003145 | ||
Soluble vascular endothelial growth factor receptor-1 (sFLT-1) mediates downregulation of FLT-1 and prevents activated neutrophils from women with preeclampsia from additional migration by VEGF. | Q52936000 | ||
Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats. | Q54661322 | ||
Soluble fms-Like Tyrosine Kinase 1 Is Increased in Preeclampsia But Not in Normotensive Pregnancies with Small-for-Gestational-Age Neonates: Relationship to Circulating Placental Growth Factor | Q56619503 | ||
First Trimester Placental Growth Factor and Soluble Fms-Like Tyrosine Kinase 1 and Risk for Preeclampsia | Q56619507 | ||
Agonistic Angiotensin II Type 1 Receptor Autoantibodies in Postpartum Women With a History of Preeclampsia | Q56981931 | ||
Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1 | Q57105968 | ||
Evidence supporting that the excess of the sVEGFR-1 concentration in maternal plasma in preeclampsia has a uterine origin | Q61845423 | ||
Circulating levels of the antiangiogenic marker sFLT-1 are increased in first versus second pregnancies | Q80379702 | ||
Leptin, IL-10 and inflammatory markers (TNF-alpha, IL-6 and IL-8) in pre-eclamptic, normotensive pregnant and healthy non-pregnant women | Q80470716 | ||
Vascular endothelial growth factor165 resolves glomerular inflammation and accelerates glomerular capillary repair in rat anti-glomerular basement membrane glomerulonephritis | Q80824106 | ||
Hypertension during pregnancy: a disorder begging for pathophysiological support | Q81397976 | ||
Angiotensin II type 1 receptor agonistic antibodies reflect fundamental alterations in the uteroplacental vasculature | Q81423834 | ||
Angiotensin II hypertension is attenuated in interleukin-6 knockout mice | Q81472565 | ||
Plasma markers of angiogenesis in pregnancy induced hypertension | Q81641949 | ||
Angiogenesis in rheumatoid arthritis | Q82627687 | ||
Reduced uterine perfusion pressure (RUPP) model for studying cardiovascular-renal dysfunction in response to placental ischemia | Q82705098 | ||
Blockade of VEGF accelerates proteinuria, via decrease in nephrin expression in rat crescentic glomerulonephritis | Q83207457 | ||
P433 | issue | 6 | |
P921 | main subject | arterial hypertension | Q41861 |
pre-eclampsia | Q61335 | ||
inflammation | Q101991 | ||
pathophysiology | Q1135939 | ||
P304 | page(s) | 480-485 | |
P577 | publication date | 2007-12-01 | |
P1433 | published in | Current Hypertension Reports | Q15746362 |
P1476 | title | Inflammatory cytokines in the pathophysiology of hypertension during preeclampsia | |
P478 | volume | 9 |
Q35151065 | 17-hydroxyprogesterone caproate significantly improves clinical characteristics of preeclampsia in the reduced uterine perfusion pressure rat model |
Q36167912 | A Common Profile of Disordered Angiogenic Factor Production and the Exacerbation of Inflammation in Early Preeclampsia, Late Preeclampsia, and Intrauterine Growth Restriction |
Q34059001 | A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia. |
Q90256049 | Adenoviral transduction of EGFR into pregnancy-adapted uterine artery endothelial cells remaps growth factor induction of endothelial dysfunction |
Q33665037 | Altered matrix metalloproteinase-2 and -9 expression/activity links placental ischemia and anti-angiogenic sFlt-1 to uteroplacental and vascular remodeling and collagen deposition in hypertensive pregnancy |
Q47799852 | Angiogenic imbalance and diminished matrix metalloproteinase-2 and -9 underlie regional decreases in uteroplacental vascularization and feto-placental growth in hypertensive pregnancy |
Q56449434 | Assessment of angiogenesis modulators in pregnant women with pre-eclampsia: a case–control study |
Q36050771 | Autoantibody-mediated angiotensin receptor activation contributes to preeclampsia through tumor necrosis factor-alpha signaling |
Q34508485 | CD4(+) T Cells Play a Critical Role in Mediating Hypertension in Response to Placental Ischemia |
Q35130793 | CD4+ T-helper cells stimulated in response to placental ischemia mediate hypertension during pregnancy |
Q33799413 | Circulating and Vascular Bioactive Factors during Hypertension in Pregnancy |
Q47688833 | Continued Investigation Into 17-OHPC: Results From the Preclinical RUPP Rat Model of Preeclampsia |
Q36528002 | Control of soluble fms-like tyrosine-1 (sFlt-1) production response to placental ischemia/hypoxia: role of tumor necrosis factor-α. |
Q26830707 | Cytokines as key players in the pathophysiology of preeclampsia |
Q51000408 | Decreased homodimerization and increased TIMP-1 complexation of uteroplacental and uterine arterial matrix metalloproteinase-9 during hypertension-in-pregnancy. |
Q46725519 | Dimethyl acetals, an indirect marker of the endogenous antioxidant plasmalogen level, are reduced in blood lipids of Sudanese pre-eclamptic subjects whose background diet is high in carbohydrate |
Q36575544 | Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia |
Q35930887 | Expression Profile of MicroRNAs and mRNAs in Human Placentas From Pregnancies Complicated by Preeclampsia and Preterm Labor |
Q35986523 | Fetal programming of body composition, obesity, and metabolic function: the role of intrauterine stress and stress biology |
Q48578792 | Heme oxygenase-1 is a potent inhibitor of placental ischemia-mediated endothelin-1 production in cultured human glomerular endothelial cells |
Q34557501 | Human infectious diseases and risk of preeclampsia: an updated review of the literature |
Q36115279 | Hypertension in response to CD4(+) T cells from reduced uterine perfusion pregnant rats is associated with activation of the endothelin-1 system. |
Q35029700 | Hypertension in response to placental ischemia during pregnancy: role of B lymphocytes |
Q34025660 | Hypertension, inflammation and T lymphocytes are increased in a rat model of HELLP syndrome |
Q28239814 | Hypertensive disorders of pregnancy |
Q36879266 | Hypoxia-independent upregulation of placental hypoxia inducible factor-1α gene expression contributes to the pathogenesis of preeclampsia |
Q37603257 | IL-27 activates human trophoblasts to express IP-10 and IL-6: implications in the immunopathophysiology of preeclampsia |
Q89450390 | Identification and characterization of methylation-mediated transcriptional dysregulation dictate methylation roles in preeclampsia |
Q91945249 | Identification of High-Risk Pregnancies in a Remote Setting Using Ambulatory Blood Pressure: The MINDI Cohort |
Q64227446 | Immune imbalance is associated with the development of preeclampsia |
Q57160415 | Immunological Basis for Recurrent Fetal Loss and Pregnancy Complications |
Q35768447 | Impact of obesity on childhood kidney |
Q34760729 | Increased expression of matrix metalloproteinase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunction |
Q38720237 | Increased vascular and uteroplacental matrix metalloproteinase-1 and -7 levels and collagen type I deposition in hypertension in pregnancy: role of TNF-α. |
Q89860687 | Inflammasomes-A Molecular Link for Altered Immunoregulation and Inflammation Mediated Vascular Dysfunction in Preeclampsia |
Q37483133 | Inflammation in rat pregnancy inhibits spiral artery remodeling leading to fetal growth restriction and features of preeclampsia |
Q39198610 | Inflammation, Autoimmunity, and Hypertension: The Essential Role of Tissue Transglutaminase |
Q43980004 | Interleukin-10 reduces inflammation, endothelial dysfunction, and blood pressure in hypertensive pregnant rats |
Q34183082 | Interleukin-1β-31C/T and -511T/C polymorphisms were associated with preeclampsia in Chinese Han population |
Q90675908 | Low-Dose Aspirin May Prevent Trophoblast Dysfunction in Women With Chlamydia Pneumoniae Infection |
Q37694496 | Lower Serum Vitamin D Metabolite Levels in Relation to Circulating Cytokines/Chemokines and Metabolic Hormones in Pregnant Women with Hypertensive Disorders |
Q34495512 | Maternal serum levels of TNF-alpha and IL-6 long after delivery in preeclamptic and normotensive pregnant women |
Q46342648 | Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia |
Q35099504 | Mesenchymal stem cells ameliorate Th1-induced pre-eclampsia-like symptoms in mice via the suppression of TNF-α expression |
Q36002112 | Moderate Exercise Attenuates Lipopolysaccharide-Induced Inflammation and Associated Maternal and Fetal Morbidities in Pregnant Rats |
Q33349894 | Molecular and vascular targets in the pathogenesis and management of the hypertension associated with preeclampsia |
Q58911048 | Molecular mechanisms of preeclampsia |
Q38017497 | Pathogenesis of pre-eclampsia: marinobufagenin and angiogenic imbalance as biomarkers of the syndrome |
Q39423454 | Pathophysiology and Current Clinical Management of Preeclampsia |
Q35208938 | Placental expression of miR-517a/b and miR-517c contributes to trophoblast dysfunction and preeclampsia |
Q36225249 | Placental secretion of interleukin-1 and interleukin-1 receptor antagonist in preeclampsia: effect of magnesium sulfate |
Q33694254 | Polymorphisms in inflammatory genes are associated with term small for gestational age and preeclampsia |
Q41046727 | Preeclampsia/Eclampsia candidate genes show altered methylation in maternal leukocytes of preeclamptic women at the time of delivery |
Q37057315 | Pregnancy Complications and Later Development of Hypertension |
Q40019506 | Prenatal nutrition: a critical window of opportunity for mother and child |
Q35071152 | Prenatal stress and developmental programming of human health and disease risk: concepts and integration of empirical findings |
Q35864583 | Prevention of Defective Placentation and Pregnancy Loss by Blocking Innate Immune Pathways in a Syngeneic Model of Placental Insufficiency |
Q36748065 | Protein Kinase C Inhibitors as Modulators of Vascular Function and their Application in Vascular Disease |
Q99724694 | Racial Differences in the Biochemical Effects of Stress in Pregnancy |
Q33666742 | Recombinant vascular endothelial growth factor 121 infusion lowers blood pressure and improves renal function in rats with placentalischemia-induced hypertension |
Q34429164 | Regulation of sFlt-1 and VEGF secretion by adenosine under hypoxic conditions in rat placental villous explants |
Q42356968 | Restoring placental growth factor-soluble fms-like tyrosine kinase-1 balance reverses vascular hyper-reactivity and hypertension in pregnancy |
Q33793455 | Risk factors and mediators of the vascular dysfunction associated with hypertension in pregnancy |
Q35324147 | Single administration of ultra-low-dose lipopolysaccharide in rat early pregnancy induces TLR4 activation in the placenta contributing to preeclampsia |
Q52594781 | The Endothelin System: A Critical Player in the Pathophysiology of Preeclampsia. |
Q37729072 | The Endothelin Type A Receptor as a Potential Therapeutic Target in Preeclampsia |
Q57922114 | The association between urinary tract infection during pregnancy and preeclampsia: A meta-analysis |
Q35132440 | The genetics of pre-eclampsia and other hypertensive disorders of pregnancy |
Q37672033 | The immunomodulatory roles of macrophages at the maternal-fetal interface |
Q34267611 | The possible role of extravillous trophoblast-derived exosomes on the uterine spiral arterial remodeling under both normal and pathological conditions |
Q46308477 | The relationship between circulating tissue transglutaminase, soluble fms-like tyrosine kinase-1, soluble endoglin and vascular endothelial growth factor in pre-eclampsia |
Q57787116 | The relationship between inflammatory factor expression and blood pressure and urinary protein in the placenta of gestational hypertension rats |
Q45164219 | The significance of -786T > C polymorphism of endothelial NO synthase (eNOS) gene in severe preeclampsia. |
Q36309225 | Timing of ischemic insult alters fetal growth trajectory, maternal angiogenic balance, and markers of renal oxidative stress in the pregnant rat. |
Q33737470 | Tissue transglutaminase contributes to the pathogenesis of preeclampsia and stabilizes placental angiotensin receptor type 1 by ubiquitination-preventing isopeptide modification |
Q35161111 | Unravelling the theories of pre-eclampsia: are the protective pathways the new paradigm? |
Q33781354 | Vascular and cellular calcium in normal and hypertensive pregnancy |
Q42510484 | Visceral adipose tissue activated macrophage content and inflammatory adipokine secretion is higher in pre-eclampsia than in healthy pregnancys. |
Q34533258 | Vitamin D Supplementation Suppresses Hypoxia-Stimulated Placental Cytokine Secretion, Hypertension and CD4(+) T Cell Stimulation in Response to Placental Ischemia |
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