review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.2174/187152910790780096 |
P8608 | Fatcat ID | release_6dnd4hyka5cnpalzr6fn3iepay |
P932 | PMC publication ID | 2855626 |
P698 | PubMed publication ID | 20041838 |
P5875 | ResearchGate publication ID | 40818831 |
P2093 | author name string | Raouf A Khalil | |
Stephanie J Sheppard | |||
P2860 | cites work | Antihypertensive drug therapy for mild to moderate hypertension during pregnancy | Q24246376 |
Maternal obesity and diabetes as risk factors for adverse pregnancy outcomes: differences among 4 racial/ethnic groups | Q24544895 | ||
Cigarette smoke exposure and angiogenic factors in pregnancy and preeclampsia | Q24654029 | ||
The placental problem: linking abnormal cytotrophoblast differentiation to the maternal symptoms of preeclampsia | Q24795491 | ||
Antioxidant therapy to prevent preeclampsia | Q28171421 | ||
Aspirin for the prevention of preeclampsia in women with abnormal uterine artery Doppler: a meta-analysis | Q28191497 | ||
Aspirin for prevention of preeclampsia in women with historical risk factors: a systematic review | Q28196410 | ||
Soluble endoglin contributes to the pathogenesis of preeclampsia | Q28244053 | ||
Aortic adaptation to pregnancy: elevated expression of matrix metalloproteinases-2 and -3 in rat gestation | Q28574980 | ||
Impaired angiogenesis in SHR is associated with decreased KDR and MT1-MMP expression | Q28582505 | ||
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia | Q29615916 | ||
Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptor | Q30747560 | ||
Endothelin and nitric oxide mediate reduced myogenic reactivity of small renal arteries from pregnant rats | Q31731441 | ||
[Ca(2+)](i) signaling in renal arterial smooth muscle cells of pregnant rat is enhanced during inhibition of NOS. | Q31732247 | ||
Role of endothelin B receptors in enhancing endothelium-dependent nitric oxide-mediated vascular relaxation during high salt diet | Q32071788 | ||
Molecular mechanisms of preeclampsia | Q33344105 | ||
The genetic aspects of pre-eclampsia: achievements and limitations | Q33345506 | ||
Human genetic selection on the MTHFR 677C>T polymorphism | Q33387977 | ||
Prolonged blockade of nitric oxide synthesis in gravid rats produces sustained hypertension, proteinuria, thrombocytopenia, and intrauterine growth retardation | Q33490821 | ||
Endothelial cell responses to hypoxic stress | Q33535019 | ||
Inhibition of inducible nitric oxide synthase and superoxide production reduces matrix metalloproteinase-9 activity and restores coronary vasomotor function in rat cardiac allografts | Q45008785 | ||
Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta | Q45061635 | ||
Changes in endothelium-derived hyperpolarizing factor in hypertension and ageing: response to chronic treatment with renin-angiotensin system inhibitors | Q45102837 | ||
Effects of vasoactive agents on intracellular calcium and force in myometrial and subcutaneous resistance arteries isolated from preeclamptic, pregnant, and nonpregnant woman | Q45254319 | ||
Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo. | Q45256231 | ||
Pregnancy outcome and fibrinolytic, endothelial and coagulation markers in women undergoing uterine artery Doppler screening at 23 weeks | Q46334260 | ||
Comparison of intramuscular magnesium sulfate with low dose intravenous magnesium sulfate regimen for treatment of eclampsia | Q46334541 | ||
Babies, pre-eclamptic mothers and grandparents: a three-generation phenotyping study | Q46339871 | ||
Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions? | Q46342132 | ||
Discovery of a spontaneous genetic mouse model of preeclampsia | Q46351794 | ||
Angiogenin and vascular endothelial growth factor in pregnancies complicated by preeclampsia | Q46440312 | ||
Increased phospholipase A2 and thromboxane but not prostacyclin production by placental trophoblast cells from normal and preeclamptic pregnancies cultured under hypoxia condition | Q46454719 | ||
Angiotensin-converting enzyme inhibitors reveal non-NO-, non-prostacycline-mediated endothelium-dependent relaxation in internal thoracic artery of hypertensive patients | Q46590537 | ||
Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats | Q46697023 | ||
Evidence that inward rectifier K+ channels mediate relaxation by the PGI2 receptor agonist cicaprost via a cyclic AMP-independent mechanism | Q46719781 | ||
Insulin-like factor 3 levels in amniotic fluid of human male fetuses. | Q46726063 | ||
Effect of L-arginine therapy on the glomerular injury of preeclampsia: a randomized controlled trial | Q46777480 | ||
Angiotensin II infusion alters vascular function in mouse resistance vessels: roles of O and endothelium | Q46844588 | ||
Women with preeclampsia have higher plasma endothelin levels than women with normal pregnancies | Q46878600 | ||
Endothelium-derived hyperpolarizing factor in preeclampsia: heterogeneous contribution, mechanisms, and morphological prerequisites | Q46886600 | ||
The positive inotropic effect of angiotensin II: role of endothelin-1 and reactive oxygen species | Q46966458 | ||
Plasma- and urine concentrations of nitrite/nitrate and cyclic Guanosinemonophosphate in intrauterine growth restricted and preeclamptic pregnancies | Q46987465 | ||
Ultrasonographic measurement of thymus size in IUGR fetuses: a marker of the fetal immunoendocrine response to malnutrition | Q47191079 | ||
The levels of leptin, adiponectin, and resistin in normal weight, overweight, and obese pregnant women with and without preeclampsia | Q47369214 | ||
Placental trophoblast-derived factors diminish endothelial barrier function | Q47650864 | ||
Characterization of endothelium- dependent relaxation in guinea pig basilar artery - effect of hypoxia and role of cytochrome P450 mono-oxygenase. | Q47694967 | ||
Endothelial dysfunction in preeclampsia | Q47879591 | ||
Decreased endothelium-dependent vascular relaxation during reduction of uterine perfusion pressure in pregnant rat. | Q50514586 | ||
Systemic hemodynamic and regional blood flow changes in response to chronic reductions in uterine perfusion pressure in pregnant rats. | Q50952787 | ||
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of interleukin 6. | Q51139503 | ||
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of tumor necrosis factor-alpha. | Q51359651 | ||
Plasma nitric oxide, endothelin-1, arginase and superoxide dismutase in pre-eclamptic women. | Q51436935 | ||
Hypocalcemia and pregnancy-induced hypertension produced by low-calcium diet. | Q51594970 | ||
A novel mouse model for preeclampsia by transferring activated th1 cells into normal pregnant mice. | Q51816934 | ||
Alteration of serum soluble endoglin levels after the onset of preeclampsia is more pronounced in women with early-onset. | Q51865183 | ||
Environmental lead level and pregnancy-induced hypertension. | Q51965294 | ||
Endothelial function in myometrial resistance arteries of normal pregnant women perfused with syncytiotrophoblast microvillous membranes. | Q52055001 | ||
Modulation of angiotensin II receptor expression during development and regression of hypoxic pulmonary hypertension. | Q52170561 | ||
The effect of placental syncytiotrophoblast microvillous membranes from normal and pre-eclamptic women on the growth of endothelial cells in vitro. | Q52515281 | ||
Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. | Q53600812 | ||
[The role of calcium in the regulation of normal vascular tone and in arterial hypertension] | Q53919958 | ||
Maternal plasma vascular endothelial growth factor concentrations in normal and hypertensive pregnancies and their relationship to peripheral vascular resistance. | Q54021736 | ||
Increased levels of pregnancy-associated plasma protein-A2 in the serum of pre-eclamptic patients. | Q54515085 | ||
Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction. | Q54594222 | ||
Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats. | Q54661322 | ||
Soluble fms-like Tyrosine Kinase 1 | Q56619509 | ||
Fine mapping and SNP analysis of positional candidates at the preeclampsia susceptibility locus (PREG1) on chromosome 2 | Q57670256 | ||
L-Arginine Supplementation in Patients with Gestational Hypertension: A Pilot Study | Q60690363 | ||
Soluble Flt-1 as a diagnostic marker of pre-eclampsia | Q62504254 | ||
Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia | Q33679047 | ||
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor | Q33848380 | ||
Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies | Q33930498 | ||
Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP. | Q33940517 | ||
Placental growth factor is a potent vasodilator of rat and human resistance arteries. | Q34052025 | ||
Recurrence of pre-eclampsia across generations: exploring fetal and maternal genetic components in a population based cohort | Q34081523 | ||
Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia | Q34110398 | ||
Protein kinase C isoforms as specific targets for modulation of vascular smooth muscle function in hypertension | Q34293890 | ||
Angiotensin and cytoskeletal proteins: role in vascular remodeling | Q34492824 | ||
World Health Organization randomized trial of calcium supplementation among low calcium intake pregnant women | Q34565461 | ||
Maternal vitamin D deficiency increases the risk of preeclampsia | Q34579840 | ||
Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia | Q34656275 | ||
Digibind attenuates cytokine TNFalpha-induced endothelial inflammatory response: potential benefit role of digibind in preeclampsia | Q34707051 | ||
Hyperglycemia and adverse pregnancy outcomes | Q34777029 | ||
1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system | Q34793842 | ||
Nutrient involvement in preeclampsia | Q35121229 | ||
The genetics of pre-eclampsia: a feto-placental or maternal problem? | Q35177399 | ||
Enhanced expression of Ang-(1-7) during pregnancy | Q35845564 | ||
Uric acid as a pathogenic factor in preeclampsia. | Q35868968 | ||
Angiotensin II and vascular inflammation. | Q36140047 | ||
Preeclampsia: recent insights | Q36288757 | ||
Could antioxidant supplementation prevent pre-eclampsia? | Q36325124 | ||
Fetal programming of hypertension | Q36341270 | ||
Brief overview of maternal triglycerides as a risk factor for pre-eclampsia. | Q36428553 | ||
Calcium supplementation during pregnancy and lactation: effects on the mother and the fetus | Q36437354 | ||
Neurovascular mechanisms of hypertension in pregnancy | Q36486193 | ||
Intrauterine growth restriction: fetal programming of hypertension and kidney disease | Q36569856 | ||
Alternative complement pathway activation fragment Bb in early pregnancy as a predictor of preeclampsia | Q36618406 | ||
Evidence of placental translation inhibition and endoplasmic reticulum stress in the etiology of human intrauterine growth restriction. | Q36778250 | ||
Gestational diabetes, pregnancy hypertension, and late vascular disease | Q36862954 | ||
Diet during pregnancy and risk of preeclampsia or gestational hypertension | Q36867915 | ||
The glomerular injury of preeclampsia | Q36883342 | ||
Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency. | Q36948563 | ||
Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction | Q37022723 | ||
Severe preeclampsia-related changes in gene expression at the maternal-fetal interface include sialic acid-binding immunoglobulin-like lectin-6 and pappalysin-2. | Q37072792 | ||
Recent progress toward the understanding of the pathophysiology of hypertension during preeclampsia | Q37079628 | ||
Endoglin in angiogenesis and vascular diseases | Q37088038 | ||
Inflammatory cytokines in the pathophysiology of hypertension during preeclampsia | Q37119326 | ||
Altered global gene expression in first trimester placentas of women destined to develop preeclampsia | Q37155561 | ||
Increased sFlt-1 to PlGF ratio in women who subsequently develop preeclampsia | Q37221219 | ||
Searching for genetic factors underlying pre-eclampsia: recent progress and persistent challenges. | Q37293822 | ||
Obesity, gestational diabetes and pregnancy outcome | Q37300560 | ||
Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant rats | Q37436219 | ||
Role of reactive oxygen species in hypertension produced by reduced uterine perfusion in pregnant rats | Q37449704 | ||
Human-specific expression of Siglec-6 in the placenta | Q38300677 | ||
Transcriptional stimulation of the eNOS gene by the stable prostacyclin analogue beraprost is mediated through cAMP-responsive element in vascular endothelial cells: close link between PGI2 signal and NO pathways | Q38351435 | ||
The impact of maternal obesity on maternal and fetal health | Q40007232 | ||
Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells | Q40418046 | ||
Paradoxical Elevation in Adiponectin Concentrations in Women With Preeclampsia | Q40559156 | ||
Effects of placental proteases on maternal and fetal blood pressure in normal pregnancy and preeclampsia | Q41092408 | ||
Mechanisms of smooth muscle contraction | Q41169589 | ||
Resistance artery smooth muscle function in pregnancy and preeclampsia | Q42516324 | ||
Nitric oxide synthase activity in placentae from women with pre-eclampsia | Q42520050 | ||
Alterations in the renin-angiotensin system in a rat model of human preeclampsia | Q43218182 | ||
Stabilization of hypoxia-inducible factor-1{alpha} by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells. | Q43413808 | ||
Association of maternal endothelial dysfunction with preeclampsia | Q43553727 | ||
Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide. | Q43576536 | ||
Regulation of prostacyclin synthesis by angiotensin II and TNF-alpha in vascular smooth muscle | Q43577316 | ||
Elevated levels of S-nitrosoalbumin in preeclampsia plasma | Q43633772 | ||
High intake of energy, sucrose, and polyunsaturated fatty acids is associated with increased risk of preeclampsia | Q43717221 | ||
The role of endothelium-derived hyperpolarizing factor in the regulation of the uterine circulation in pregnant rats | Q43745798 | ||
Longitudinal study of platelet size changes in gestation and predictive power of elevated MPV in development of pre-eclampsia | Q43872581 | ||
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats | Q43888051 | ||
Differential mechanisms of endothelium-dependent vasodilator responses in human myometrial small arteries in normal pregnancy and pre-eclampsia | Q44048792 | ||
Folic acid supplementation in early second trimester and the risk of preeclampsia | Q44054579 | ||
Enhanced thromboxane synthesis during chronic reductions in uterine perfusion pressure in pregnant rats | Q44130345 | ||
Enhanced [Ca2+]i in renal arterial smooth muscle cells of pregnant rats with reduced uterine perfusion pressure | Q44185600 | ||
Reduced function of endothelial prostacyclin in human omental resistance arteries in pre-eclampsia | Q44218040 | ||
Association between 894G>T endothelial nitric oxide synthase gene polymorphisms and metabolic syndrome | Q44401791 | ||
Pulmonary vascular endothelial growth factor and nitric oxide interaction during total cardiopulmonary bypass in neonatal pigs | Q44456864 | ||
Tumor necrosis factor alpha in the bovine oviduct during the estrous cycle: messenger RNA expression and effect on secretion of prostaglandins, endothelin-1, and angiotensin II. | Q44475138 | ||
Pre-eclampsia (EPH-gestosis)-induced decrease of MMP-s content in the umbilical cord artery | Q44555376 | ||
The M235T variant of the angiotensinogen gene is related to development of self-reported hypertension during pregnancy: the Prospect-EPIC cohort study | Q44632633 | ||
Reduced endothelial NO-cGMP-mediated vascular relaxation and hypertension in IL-6-infused pregnant rats | Q44715072 | ||
Low socioeconomic status is a risk factor for preeclampsia: the Generation R Study | Q44750267 | ||
Placental lipid peroxides and thromboxane are increased and prostacyclin is decreased in women with preeclampsia | Q44897228 | ||
The imbalance between thromboxane and prostacyclin in preeclampsia is associated with an imbalance between lipid peroxides and vitamin E in maternal blood | Q44929427 | ||
Recombinant vascular endothelial growth factor 121 attenuates hypertension and improves kidney damage in a rat model of preeclampsia | Q64377002 | ||
Pre-eclampsia and trisomy 13 | Q67592481 | ||
Plasma endothelin levels in preeclampsia: elevation and correlation with uric acid levels and renal impairment | Q68053902 | ||
Pre-eclampsia and trisomy 13: a possible association | Q69904752 | ||
Protein kinase C in uterine and systemic arteries during ovarian cycle and pregnancy | Q70116950 | ||
Chronic hypoxia selectively augments endothelium-dependent pulmonary arterial vasodilation | Q71465109 | ||
Ca(2+)-insensitive vascular protein kinase C during pregnancy and NOS inhibition | Q73087551 | ||
Plasma nitric oxide metabolites and lipid peroxide levels in preeclamptic pregnant women before and after delivery | Q73258662 | ||
Selective overexpression of the hypoxia-inducible transcription factor, HIF-2alpha, in placentas from women with preeclampsia | Q73399793 | ||
Pregnancy-associated reduction in vascular protein kinase C activity rebounds during inhibition of NO synthesis | Q73426782 | ||
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor | Q73815485 | ||
Matrix metalloproteinase-2 is elevated in the plasma of women with preeclampsia | Q74226798 | ||
Increased nitric oxide synthase activity and expression in the human uterine artery during pregnancy | Q74253964 | ||
Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant rats | Q74518978 | ||
Nitric oxide production with preeclampsia | Q74601245 | ||
Circulating levels of immunoreactive cytokines in women with preeclampsia | Q77384781 | ||
Peripheral blood mononuclear cells stimulate progesterone production by luteal cells derived from pregnant and non-pregnant women: possible involvement of interleukin-4 and interleukin-10 in corpus luteum function and differentiation | Q77519168 | ||
Tumor necrosis factor-alpha-induced hypertension in pregnant rats results in decreased renal neuronal nitric oxide synthase expression | Q77684136 | ||
Endothelin mediates renal vasodilation and hyperfiltration during pregnancy in chronically instrumented conscious rats | Q77755765 | ||
Differential expression of renal nitric oxide synthase isoforms during pregnancy in rats | Q77945719 | ||
Plasma and 24-h NO(x) and cGMP during normal pregnancy and preeclampsia in women on a reduced NO(x) diet | Q78009520 | ||
Purification and characterization of a complex from placental syncytiotrophoblast microvillous membranes which inhibits the proliferation of human umbilical vein endothelial cells | Q78018453 | ||
Nitric oxide activity in the peripheral vasculature during normotensive and preeclamptic pregnancy | Q78117582 | ||
Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs | Q78396702 | ||
Angiotensin-(1-7) in normal and preeclamptic pregnancy | Q78568866 | ||
Racial disparity in hypertensive disorders of pregnancy in New York State: a 10-year longitudinal population-based study | Q79397360 | ||
Evaluation of physiological alterations of the placenta through analysis of cell-free messenger ribonucleic acid concentrations of angiogenic factors | Q80425329 | ||
Serum levels of interleukin-6, interleukin-1beta and human chorionic gonadotropin in pre-eclamptic and normal pregnancy | Q80454204 | ||
Pre-eclampsia: clinical manifestations and molecular mechanisms | Q80482285 | ||
Recent patents on Rho signaling pathway as therapeutic target for cardiovascular diseases | Q80551190 | ||
The immunohistochemical evaluation of VEGF in placenta biopsies of pregnancies complicated by preeclampsia | Q80821578 | ||
Relationship between increased blood lead and pregnancy hypertension in women without occupational lead exposure in Tehran, Iran | Q80991877 | ||
Hypoxia is responsible for soluble vascular endothelial growth factor receptor-1 (VEGFR-1) but not for soluble endoglin induction in villous trophoblast | Q81086992 | ||
Generation of reactive oxygen species by neutrophils and endothelial cell injury in normal and preeclamptic pregnancies | Q81236313 | ||
Screening test for preeclampsia through assessment of uteroplacental blood flow and biochemical markers of oxidative stress and endothelial dysfunction | Q81305565 | ||
Tumor necrosis factor-alpha in the placenta is not elevated in pre-eclamptic patients despite its elevation in peripheral blood | Q81432957 | ||
Dietary fiber, potassium, magnesium and calcium in relation to the risk of preeclampsia | Q81878607 | ||
Calcium supplementation for the prevention of pre-eclampsia | Q82283234 | ||
P433 | issue | 1 | |
P921 | main subject | hypertension | Q95566669 |
P304 | page(s) | 33-52 | |
P577 | publication date | 2010-03-01 | |
P1433 | published in | Cardiovascular & hematological disorders drug targets | Q26867051 |
P1476 | title | Risk factors and mediators of the vascular dysfunction associated with hypertension in pregnancy | |
P478 | volume | 10 |
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