Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction

scientific article

Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1152/AJPHEART.01113.2007
P698PubMed publication ID18055511

P2093author name stringJeffrey S Gilbert
Michael J Ryan
Joey P Granger
Sydney R Murphy
Mona Sedeek
Babbette B LaMarca
P2860cites workAT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestrationQ24290268
Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptorQ24320710
Eicosanoids in preeclampsiaQ28166550
Soluble endoglin contributes to the pathogenesis of preeclampsiaQ28244053
Cardiovascular and renal sympathetic activation by blood-borne TNF-alpha in rat: the role of central prostaglandinsQ28581223
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
Long term mortality of mothers and fathers after pre-eclampsia: population based cohort studyQ33947553
Summary of the NHLBI Working Group on Research on Hypertension During PregnancyQ34182166
Decreased endothelium-dependent vascular relaxation during reduction of uterine perfusion pressure in pregnant rat.Q50514586
Systemic hemodynamic and regional blood flow changes in response to chronic reductions in uterine perfusion pressure in pregnant rats.Q50952787
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of interleukin 6.Q51139503
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of tumor necrosis factor-alpha.Q51359651
Effects of reduced uterine perfusion pressure on blood pressure and metabolic factors in pregnant rats.Q51470693
The relationship between abnormal glucose tolerance and hypertensive disorders of pregnancy in healthy nulliparous women. Calcium for Preeclampsia Prevention (CPEP) Study Group.Q51567295
Lipoprotein subfraction changes in normal pregnancy: threshold effect of plasma triglyceride on appearance of small, dense low density lipoprotein.Q51574204
Hyperinsulinemia in glucose-tolerant women with preeclampsia. A controlled study.Q51581108
Sequential changes in antiangiogenic factors in early pregnancy and risk of developing preeclampsia.Q51914188
Sympathetic neural mechanisms in normal and hypertensive pregnancy in humans.Q52862288
Relation between circulating angiotensin II type 1 receptor agonistic autoantibodies and soluble fms-like tyrosine kinase 1 in the pathogenesis of preeclampsia.Q52933863
Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.Q53600812
Expression of the placental cytokines tumor necrosis factor alpha, interleukin 1beta, and interleukin 10 is increased in preeclampsia.Q53680742
Normalization of blood pressure and renal vascular resistance in SHR with a membrane-permeable superoxide dismutase mimetic: role of nitric oxide.Q54130783
Systemic hemodynamics and regional blood flow during chronic nitric oxide synthesis inhibition in pregnant rats.Q54148277
Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats.Q54661322
Soluble fms-Like Tyrosine Kinase 1 Is Increased in Preeclampsia But Not in Normotensive Pregnancies with Small-for-Gestational-Age Neonates: Relationship to Circulating Placental Growth FactorQ56619503
First Trimester Placental Growth Factor and Soluble Fms-Like Tyrosine Kinase 1 and Risk for PreeclampsiaQ56619507
Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1Q57105968
Vitamin C and vitamin E in pregnant women at risk for pre-eclampsia (VIP trial): randomised placebo-controlled trial.Q34514153
Vitamins C and E and the risks of preeclampsia and perinatal complicationsQ34518082
Insulin resistance and its potential role in pregnancy-induced hypertensionQ35146337
Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancyQ35699115
Hypoxia and sFlt-1 in preeclampsia: the "chicken-and-egg" questionQ35920602
Role of the renin-angiotensin system in the pathogenesis of preeclampsiaQ36064478
Preeclampsia: a renal perspectiveQ36120940
Circulating angiogenic factors in the pathogenesis and prediction of preeclampsiaQ36288766
Clinical and biochemical evidence of endothelial cell dysfunction in the pregnancy syndrome preeclampsiaQ37421465
Current topic: pre-eclampsia and the placentaQ37492460
Endothelin-1 triggers placental oxidative stress pathways: putative role in preeclampsiaQ40433104
Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB.Q40526010
Endoglin regulates nitric oxide-dependent vasodilatationQ40597391
Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective studyQ40802999
Glucose intolerance as a predictor of hypertension in pregnancyQ41030613
Preeclampsia: an endothelial cell disorderQ41281924
Importance of prostaglandins in hypertension during reduced uteroplacental perfusion pressureQ41284596
Nitric oxide and pregnancyQ41449537
Placental cytokines and the pathogenesis of preeclampsiaQ41452017
CD105 prevents apoptosis in hypoxic endothelial cellsQ42441203
Interleukin-1beta and neurogenic control of blood pressure in normal rats and rats with chronic renal failureQ43495878
Association of maternal endothelial dysfunction with preeclampsiaQ43553727
Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide.Q43576536
Correlation between soluble endoglin, vascular endothelial growth factor receptor-1, and adipocytokines in preeclampsiaQ43739445
High-salt diet enhances vascular reactivity in pregnant rats with normal and reduced uterine perfusion pressureQ43744797
Effect of angiotensin II synthesis blockade on the hypertensive response to chronic reductions in uterine perfusion pressure in pregnant rats.Q43744800
Vascular endothelial growth factor induces manganese-superoxide dismutase expression in endothelial cells by a Rac1-regulated NADPH oxidase-dependent mechanismQ43771298
Enhanced thromboxane synthesis during chronic reductions in uterine perfusion pressure in pregnant ratsQ44130345
Insulin, insulin-like growth factor-1, and insulin resistance in women with pregnancy-induced hypertensionQ44141451
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cellsQ44320558
Agonistic autoantibodies directed against the angiotensin II AT1 receptor in patients with preeclampsiaQ44413491
Cytochrome P-450 inhibition attenuates hypertension induced by reductions in uterine perfusion pressure in pregnant ratsQ44752496
L-arginine attenuates hypertension in pregnant rats with reduced uterine perfusion pressureQ44760481
TNF alpha concentrations and mRNA expression are increased in preeclamptic placentasQ45102738
Maternal-placental interactions of oxidative stress and antioxidants in preeclampsiaQ45112360
Tales from the crypt: beta-catenin in the development of juvenile polyps: commentary on the article by Iwamoto et al. on page 4.Q45932850
Potential role of endothelin-1 in normal and hypertensive pregnanciesQ46165905
Uteroplacental ischemia results in proteinuric hypertension and elevated sFLT-1.Q46339760
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human mesangial cells and induce interleukin-6 and plasminogen activator inhibitor-1 secretionQ46344658
Maternal and fetal modulators of lipid metabolism correlate with the development of preeclampsiaQ46359043
Circulating factors as markers and mediators of endothelial cell dysfunction in preeclampsiaQ46433836
Experimental preeclampsia produced by chronic constriction of the lower aorta: validation with longitudinal blood pressure measurements in conscious rhesus monkeysQ46540991
Increased depth of trophoblast invasion after chronic constriction of the lower aorta in rhesus monkeysQ46733986
Increased AT(1) receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsivenessQ46841539
Enhanced endothelin synthesis by endothelial cells exposed to sera from pregnant rats with decreased uterine perfusionQ46877931
Women with preeclampsia have higher plasma endothelin levels than women with normal pregnanciesQ46878600
Circulating angiogenic factors and the risk of preeclampsiaQ47217679
Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant womenQ47770771
Amniotic vascular endothelial growth factor (VEGF) and nitric oxide (NO) in women with subsequent preeclampsiaQ47907082
Insulin resistance and alterations in angiogenesis: additive insults that may lead to preeclampsiaQ47945074
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectpre-eclampsiaQ61335
arterial hypertensionQ41861
endotheliumQ111140
pathophysiologyQ1135939
P304page(s)H541-50
P577publication date2007-11-30
P1433published inAmerican Journal of Physiology Heart and Circulatory PhysiologyQ3193662
P1476titlePathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction
P478volume294

Reverse relations

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