Molecular and vascular targets in the pathogenesis and management of the hypertension associated with preeclampsia

scientific article

Molecular and vascular targets in the pathogenesis and management of the hypertension associated with preeclampsia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2174/187152510792481234
P932PMC publication ID2951603
P698PubMed publication ID20923405
P5875ResearchGate publication ID47348880

P2093author name stringRaouf A Khalil
Ossama M Reslan
P2860cites workPrevalence and Trends in Obesity Among US Adults, 1999-2000Q22253005
Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cellsQ24337230
Maternal obesity and diabetes as risk factors for adverse pregnancy outcomes: differences among 4 racial/ethnic groupsQ24544895
VEGF inhibition and renal thrombotic microangiopathyQ24632792
Correlation between oral sex and a low incidence of preeclampsia: a role for soluble HLA in seminal fluid?Q28137967
Eicosanoids in preeclampsiaQ28166550
Primary, secondary, and tertiary prevention of pre-eclampsiaQ28176253
Seminal 'priming' for protection from pre-eclampsia-a unifying hypothesisQ28191647
Low-molecular-weight heparin for the prevention of obstetric complications in women with thrombophiliasQ28193116
Thrombophilia and severe preeclampsia: time to screen and treat in future pregnancies?Q28193351
Aspirin for prevention of preeclampsia in women with historical risk factors: a systematic reviewQ28196410
Human placental vascular development: vasculogenic and angiogenic (branching and nonbranching) transformation is regulated by vascular endothelial growth factor-A, angiopoietin-1, and angiopoietin-2Q28221171
Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnanciesQ28222709
Soluble endoglin contributes to the pathogenesis of preeclampsiaQ28244053
Hypertension produced by placental ischemia in pregnant rats is associated with increased soluble endoglin expressionQ28573546
Aortic adaptation to pregnancy: elevated expression of matrix metalloproteinases-2 and -3 in rat gestationQ28574980
Immunosuppression improves blood pressure and endothelial function in a rat model of pregnancy-induced hypertensionQ28582225
Impaired angiogenesis in SHR is associated with decreased KDR and MT1-MMP expressionQ28582505
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor proteinQ29615931
How matrix metalloproteinases regulate cell behaviorQ29620360
Trial of Calcium to Prevent PreeclampsiaQ73485563
Increased nitric oxide synthase activity and expression in the human uterine artery during pregnancyQ74253964
Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant ratsQ74518978
Nitric oxide production with preeclampsiaQ74601245
Is preeclampsia an infectious disease?Q77153770
Circulating levels of immunoreactive cytokines in women with preeclampsiaQ77384781
Activation of leukocytes during the uteroplacental passage in preeclampsiaQ77513220
Peripheral blood mononuclear cells stimulate progesterone production by luteal cells derived from pregnant and non-pregnant women: possible involvement of interleukin-4 and interleukin-10 in corpus luteum function and differentiationQ77519168
Tumor necrosis factor-alpha-induced hypertension in pregnant rats results in decreased renal neuronal nitric oxide synthase expressionQ77684136
Surgically obtained sperm, and risk of gestational hypertension and pre-eclampsiaQ77731627
Endothelin mediates renal vasodilation and hyperfiltration during pregnancy in chronically instrumented conscious ratsQ77755765
Microalbuminuria after pregnancy complicated by pre-eclampsiaQ77799245
Plasma and 24-h NO(x) and cGMP during normal pregnancy and preeclampsia in women on a reduced NO(x) dietQ78009520
Stimulated mechanisms of Ca2+ entry into vascular smooth muscle during NO synthesis inhibition in pregnant ratsQ78020557
Nutritional interventions for the prevention of maternal morbidityQ78171557
Trial of prophylactic administration of TXA2 synthetase inhibitor, ozagrel hydrochloride, for preeclampsiaQ78220660
Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigsQ78396702
Expression of estrogen receptor-alpha, estrogen receptor-beta and placental endothelial and inducible NO synthase in intrauterine growth-restricted and normal placentalsQ79255453
Vascular matrix metalloproteinase-9 mediates the inhibition of myogenic reactivity in small arteries isolated from rats after short-term administration of relaxinQ79278420
Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1.Q37447371
Accuracy of serum uric acid as a predictive test for maternal complications in pre-eclampsia: bivariate meta-analysis and decision analysisQ37525274
Control of hypertension in pregnancyQ37628832
Levels of antibodies against cytomegalovirus and Chlamydophila pneumoniae are increased in early onset pre-eclampsiaQ37868905
Human-specific expression of Siglec-6 in the placentaQ38300677
Evidence for Declining Extracellular Calcium Uptake and Protein Kinase C Activity in Uterine Arterial Smooth Muscle during Gestation in Gilts1Q38330292
Effect of a low calcium intake on the vascular sensitivity to angiotensin II in normotensive pregnant ratsQ38331357
Transcriptional stimulation of the eNOS gene by the stable prostacyclin analogue beraprost is mediated through cAMP-responsive element in vascular endothelial cells: close link between PGI2 signal and NO pathwaysQ38351435
Study of plasma adrenomedullin level in normal pregnancy and preclampsia.Q39446260
Decreased fractional urinary calcium excretion and serum 1,25-dihydroxyvitamin D and IGF-I levels in preeclampsiaQ79664842
Renal angiotensin-II receptors expression changes in a model of preeclampsiaQ80238082
Mesangial AT1/B2 receptor heterodimers contribute to angiotensin II hyperresponsiveness in experimental hypertensionQ80361560
Serum levels of interleukin-6, interleukin-1beta and human chorionic gonadotropin in pre-eclamptic and normal pregnancyQ80454204
Prepregnancy diabetes and risk of placental vascular diseaseQ80515997
Recent patents on Rho signaling pathway as therapeutic target for cardiovascular diseasesQ80551190
Circulating angiogenic factors in singleton vs multiple-gestation pregnanciesQ80564650
ADAM12s in maternal serum as a potential marker of pre-eclampsiaQ80673251
Adhesion molecules changes at 20 gestation weeks in pregnancies complicated by preeclampsiaQ80812036
Serum visfatin levels in late pregnancy and pre-eclampsiaQ80999389
Leptin, soluble leptin receptor and leptin gene polymorphism in relation to preeclampsia riskQ81009011
Effects of age, gender, ethnicity, diurnal variation and exercise on circulating levels of matrix metalloproteinases (MMP)-2 and -9, and their inhibitors, tissue inhibitors of matrix metalloproteinases (TIMP)-1 and -2Q81194988
Generation of reactive oxygen species by neutrophils and endothelial cell injury in normal and preeclamptic pregnanciesQ81236313
Tumor necrosis factor-alpha in the placenta is not elevated in pre-eclamptic patients despite its elevation in peripheral bloodQ81432957
Pre-eclampsiaQ81446389
Circulating concentrations of sFlt1 (soluble fms-like tyrosine kinase 1) in fetal and maternal serum during pre-eclampsiaQ81813556
Dietary fiber, potassium, magnesium and calcium in relation to the risk of preeclampsiaQ81878607
First-trimester serum levels of soluble endoglin and soluble fms-like tyrosine kinase-1 as first-trimester markers for late-onset preeclampsiaQ81931104
Circulating angiogenic proteins in trisomy 13Q82150298
Calcium supplementation for the prevention of pre-eclampsiaQ82283234
Twin pregnancy with complete hydatidiform mole and coexistent fetus: obstetrical and oncological outcomes in a series of 14 casesQ83296614
Prediction of preeclampsia by analysis of cell-free messenger RNA in maternal plasmaQ83351931
An automated method for the determination of the sFlt-1/PIGF ratio in the assessment of preeclampsiaQ84768567
The impact of maternal obesity on maternal and fetal healthQ40007232
Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective studyQ40802999
Preeclampsia: an excessive maternal inflammatory response to pregnancyQ40824430
Hyperuricemia and xanthine oxidase in preeclampsia, revisitedQ40951966
Effect of calcium supplementation on pregnancy-induced hypertension and preeclampsia: a meta-analysis of randomized controlled trialsQ40970723
Mechanisms of smooth muscle contractionQ41169589
Nitric oxide and pregnancyQ41449537
Postpartum renal lesions in women with pre-eclampsiaQ41682946
Resistance artery smooth muscle function in pregnancy and preeclampsiaQ42516324
Stabilization of hypoxia-inducible factor-1{alpha} by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells.Q43413808
Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide.Q43576536
Regulation of prostacyclin synthesis by angiotensin II and TNF-alpha in vascular smooth muscleQ43577316
Neutrophil activation induced by placental factors in normal and pre-eclamptic pregnancies in vitroQ43664278
The role of endothelium-derived hyperpolarizing factor in the regulation of the uterine circulation in pregnant ratsQ43745798
Longitudinal study of platelet size changes in gestation and predictive power of elevated MPV in development of pre-eclampsiaQ43872581
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in ratsQ43888051
Differential mechanisms of endothelium-dependent vasodilator responses in human myometrial small arteries in normal pregnancy and pre-eclampsiaQ44048792
Folic acid supplementation in early second trimester and the risk of preeclampsiaQ44054579
Enhanced [Ca2+]i in renal arterial smooth muscle cells of pregnant rats with reduced uterine perfusion pressureQ44185600
Reduced function of endothelial prostacyclin in human omental resistance arteries in pre-eclampsiaQ44218040
Association between 894G>T endothelial nitric oxide synthase gene polymorphisms and metabolic syndromeQ44401791
Pulmonary vascular endothelial growth factor and nitric oxide interaction during total cardiopulmonary bypass in neonatal pigsQ44456864
Tumor necrosis factor alpha in the bovine oviduct during the estrous cycle: messenger RNA expression and effect on secretion of prostaglandins, endothelin-1, and angiotensin II.Q44475138
Pre-eclampsia (EPH-gestosis)-induced decrease of MMP-s content in the umbilical cord arteryQ44555376
Levels of oxidative stress and redox-related molecules in the placenta in preeclampsia and fetal growth restrictionQ44629064
The M235T variant of the angiotensinogen gene is related to development of self-reported hypertension during pregnancy: the Prospect-EPIC cohort studyQ44632633
Reduced endothelial NO-cGMP-mediated vascular relaxation and hypertension in IL-6-infused pregnant ratsQ44715072
Endothelin-1 promotes Ca2+ antagonist-insensitive coronary smooth muscle contraction via activation of epsilon-protein kinase C.Q44774841
Interpregnancy weight change and risk of adverse pregnancy outcomes: a population-based studyQ44822507
Maternal levels of prostacyclin, thromboxane, vitamin E, and lipid peroxides throughout normal pregnancyQ44929423
Inhibition of inducible nitric oxide synthase and superoxide production reduces matrix metalloproteinase-9 activity and restores coronary vasomotor function in rat cardiac allograftsQ45008785
Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aortaQ45061635
Paternal and maternal components of the predisposition to preeclampsiaQ45084472
A novel human-specific soluble vascular endothelial growth factor receptor 1: cell-type-specific splicing and implications to vascular endothelial growth factor homeostasis and preeclampsiaQ45143705
Matrix metalloproteinase-specific inhibition of Ca2+ entry mechanisms of vascular contractionQ45159052
Effects of vasoactive agents on intracellular calcium and force in myometrial and subcutaneous resistance arteries isolated from preeclamptic, pregnant, and nonpregnant womanQ45254319
Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo.Q45256231
Plasma-mediated vascular dysfunction in the reduced uterine perfusion pressure model of preeclampsia: a microvascular characterization.Q45947357
Maternal ethnicity, paternal ethnicity, and parental ethnic discordance: predictors of preeclampsia.Q45961711
GRP78 as a marker of pre-eclampsia: an exploratory study.Q45989281
Insulin resistance and preeclampsia in gestational diabetes mellitusQ46201840
Possible gene-gene interaction of KIR2DL4 with its cognate ligand HLA-G in modulating risk for preeclampsia.Q46333261
Pregnancy outcome and fibrinolytic, endothelial and coagulation markers in women undergoing uterine artery Doppler screening at 23 weeksQ46334260
Metabolic syndrome in normal and complicated pregnanciesQ46338732
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human mesangial cells and induce interleukin-6 and plasminogen activator inhibitor-1 secretionQ46344658
Pregnancy-related mortality from preeclampsia and eclampsiaQ46353535
Angiogenin and vascular endothelial growth factor in pregnancies complicated by preeclampsiaQ46440312
Increased phospholipase A2 and thromboxane but not prostacyclin production by placental trophoblast cells from normal and preeclamptic pregnancies cultured under hypoxia conditionQ46454719
Evidence that inward rectifier K+ channels mediate relaxation by the PGI2 receptor agonist cicaprost via a cyclic AMP-independent mechanismQ46719781
Insulin-like factor 3 levels in amniotic fluid of human male fetuses.Q46726063
Effect of L-arginine therapy on the glomerular injury of preeclampsia: a randomized controlled trialQ46777480
Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteinsQ46789404
Uric acid concentrations in early pregnancy among preeclamptic women with gestational hyperuricemia at deliveryQ46876317
Women with preeclampsia have higher plasma endothelin levels than women with normal pregnanciesQ46878600
Endothelium-derived hyperpolarizing factor in preeclampsia: heterogeneous contribution, mechanisms, and morphological prerequisitesQ46886600
Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptorQ30747560
Antiplatelet agents for preventing and treating pre-eclampsia.Q30867355
[Ca(2+)](i) signaling in renal arterial smooth muscle cells of pregnant rat is enhanced during inhibition of NOS.Q31732247
Role of endothelin B receptors in enhancing endothelium-dependent nitric oxide-mediated vascular relaxation during high salt dietQ32071788
Maternal serum inhibin-A and activin-A levels in the first trimester of pregnancies developing pre-eclampsiaQ33371864
Human genetic selection on the MTHFR 677C>T polymorphismQ33387977
Vascular and cellular calcium in normal and hypertensive pregnancyQ33781354
Fetal and maternal contributions to risk of pre-eclampsia: population based studyQ33783098
Invasive cytotrophoblast apoptosis in pre-eclampsiaQ33848112
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studiesQ33930498
Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP.Q33940517
ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002.Q33990220
Disentangling fetal and maternal susceptibility for pre-eclampsia: a British multicenter candidate-gene studyQ34021020
The extracellular matrix can regulate vascular cell migration, proliferation, and survival: relationships to vascular diseaseQ34022649
Placental growth factor is a potent vasodilator of rat and human resistance arteries.Q34052025
Genetic conflicts in human pregnancyQ34060435
Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxiaQ34110398
Hypoxia-inducible factor 1: control of oxygen homeostasis in health and diseaseQ34236127
Protein kinase C isoforms as specific targets for modulation of vascular smooth muscle function in hypertensionQ34293890
Matrix metalloproteinases: they're not just for matrix anymore!Q34360566
Latest advances in understanding preeclampsiaQ34425288
Angiotensin and cytoskeletal proteins: role in vascular remodelingQ34492824
Vitamins C and E and the risks of preeclampsia and perinatal complicationsQ34518082
Maternal vitamin D deficiency increases the risk of preeclampsiaQ34579840
Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsiaQ34656275
Chymotrypsin-like protease (chymase) mediates endothelial activation by factors derived from preeclamptic placentasQ34707016
1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin systemQ34793842
Nutrient involvement in preeclampsiaQ35121229
The genetics of pre-eclampsia: a feto-placental or maternal problem?Q35177399
HLA-G, pre-eclampsia, immunity and vascular eventsQ35190892
Subclassification of preeclampsiaQ35196220
Molecular and biological properties of the vascular endothelial growth factor family of proteinsQ35313427
The potential benefits of using fish oil in relation to preterm labor: the case for a randomized controlled trial?Q35583130
Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signalingQ35681804
Enhanced expression of Ang-(1-7) during pregnancyQ35845564
Abnormal placentation and the syndrome of preeclampsiaQ35941005
Developmental biology of the placenta and the origins of placental insufficiencyQ36030154
Angiotensin II and vascular inflammation.Q36140047
Preeclampsia: recent insightsQ36288757
Could antioxidant supplementation prevent pre-eclampsia?Q36325124
New insights into the biology of preeclampsiaQ36371864
Neurovascular mechanisms of hypertension in pregnancyQ36486193
Maternal serum soluble CD30 is increased in normal pregnancy, but decreased in preeclampsia and small for gestational age pregnanciesQ36512063
Alternative complement pathway activation fragment Bb in early pregnancy as a predictor of preeclampsiaQ36618406
Evidence of placental translation inhibition and endoplasmic reticulum stress in the etiology of human intrauterine growth restriction.Q36778250
The role of the immune system in preeclampsiaQ36791219
Assignment of the vascular endothelial growth factor gene to human chromosome 6p21.3.Q36796674
Gestational diabetes, pregnancy hypertension, and late vascular diseaseQ36862954
The glomerular injury of preeclampsiaQ36883342
Vascular endothelial growth factor is increased in patients with preeclampsiaQ36888688
Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency.Q36948563
Prolonged increases in vein wall tension increase matrix metalloproteinases and decrease constriction in rat vena cava: Potential implications in varicose veinsQ36953739
Preeclampsia and angiogenic imbalanceQ36971766
Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunctionQ37022723
Severe preeclampsia-related changes in gene expression at the maternal-fetal interface include sialic acid-binding immunoglobulin-like lectin-6 and pappalysin-2.Q37072792
Inflammatory cytokines in the pathophysiology of hypertension during preeclampsiaQ37119326
Altered global gene expression in first trimester placentas of women destined to develop preeclampsiaQ37155561
Differential [Ca2+]i signaling of vasoconstriction in mesenteric microvessels of normal and reduced uterine perfusion pregnant ratsQ37200099
Susceptibility loci for preeclampsia on chromosomes 2p25 and 9p13 in Finnish familiesQ37205410
Increased sFlt-1 to PlGF ratio in women who subsequently develop preeclampsiaQ37221219
Potential markers of preeclampsia--a reviewQ37278804
Searching for genetic factors underlying pre-eclampsia: recent progress and persistent challenges.Q37293822
Uric acid attenuates trophoblast invasion and integration into endothelial cell monolayersQ37298028
Maternal serum and amniotic fluid inhibin A levels in women who subsequently develop severe preeclampsiaQ37313333
The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancyQ37328814
Soluble and membranous vascular endothelial growth factor receptor-2 in pregnancies complicated by pre-eclampsiaQ37400965
The levels of leptin, adiponectin, and resistin in normal weight, overweight, and obese pregnant women with and without preeclampsiaQ47369214
Weight loss regulates inflammation-related genes in white adipose tissue of obese subjectsQ47402001
Trends in fetal and infant survival following preeclampsiaQ47578441
Increased visfatin and leptin in pregnancies complicated by pre-eclampsiaQ47673405
Association of -634G/C and 936C/T polymorphisms of the vascular endothelial growth factor with spontaneous preterm deliveryQ47836743
First trimester maternal serum placental protein 13 for the prediction of pre-eclampsia in women with a priori high riskQ47872838
Endothelial dysfunction in preeclampsiaQ47879591
Vascular contraction and preeclampsia: downregulation of the Angiotensin receptor 1 by hemopexin in vitroQ47884975
Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsiaQ47915288
Guidelines for the management of hypertensive disorders of pregnancy 2008.Q48421837
Calcium supplementation is associated with endothelium dependent attenuation of vascular smooth muscle reactivity in normotensive pregnant and nonpregnant rats.Q50525147
Systemic hemodynamic and regional blood flow changes in response to chronic reductions in uterine perfusion pressure in pregnant rats.Q50952787
Folic acid improves endothelial dysfunction in type 2 diabetes--an effect independent of homocysteine-lowering.Q51493196
Hypocalcemia and pregnancy-induced hypertension produced by low-calcium diet.Q51594970
Evaluation of metalloproteinases 2 and 9 and their inhibitors in physiologic and pre-eclamptic pregnancy.Q51767630
Relaxin is essential for systemic vasodilation and increased global arterial compliance during early pregnancy in conscious rats.Q51793504
Decreased serum levels of kisspeptin in early pregnancy are associated with intra-uterine growth restriction and pre-eclampsia.Q51931004
The importance of genetic and environmental effects for pre-eclampsia and gestational hypertension: a family study.Q52003519
Decidual NK cells regulate key developmental processes at the human fetal-maternal interface.Q52010655
Effective prediction of preeclampsia by a combined ratio of angiogenesis-related factors.Q53538854
Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.Q53600812
Neutrophil activation in pregnancy-induced hypertension.Q53684496
Cellular mRNA expressions of anti-oxidant factors in the blood of preeclamptic women.Q54485033
Increased levels of pregnancy-associated plasma protein-A2 in the serum of pre-eclamptic patients.Q54515085
Twin pregnancy and the risk of preeclampsia: bigger placenta or relative ischemia?Q54551217
Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction.Q54594222
Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats.Q54661322
Performance of a panel of maternal serum markers in predicting preeclampsia at 11-15 weeks' gestationQ56994317
Fine mapping and SNP analysis of positional candidates at the preeclampsia susceptibility locus (PREG1) on chromosome 2Q57670256
Maternal and fetal genetic factors account for most of familial aggregation of preeclampsia: A population-based Swedish cohort studyQ57697489
Neutralization of Circulating Vascular Endothelial Growth Factor (VEGF) by Anti-VEGF Antibodies and Soluble VEGF Receptor 1 (sFlt-1) Induces ProteinuriaQ58214894
Neutrophil function in women with pre-eclampsiaQ59367361
L-Arginine Supplementation in Patients with Gestational Hypertension: A Pilot StudyQ60690363
Neutrophil activation in preeclampsia and isolated intrauterine growth restrictionQ60947615
A Vascular Endothelial Growth Factor Antagonist Is Produced by the Human Placenta and Released into the Maternal Circulation1Q61479346
Hypoxia-Inducible Factor-1 (HIF-1)Q61645733
First-trimester maternal serum pregnancy-associated plasma protein-A and pre-eclampsiaQ61826563
Polymorphisms of FAS and FAS ligand genes in preeclamptic womenQ61851339
Plasma level of soluble c-Met is tightly associated with the clinical risk of preeclampsiaQ61964340
Plasma endothelin levels in preeclampsia: elevation and correlation with uric acid levels and renal impairmentQ68053902
T cell awareness of paternal alloantigens during pregnancyQ71768391
Risk factors for severe preeclampsiaQ72291387
Plasma nitric oxide metabolites and lipid peroxide levels in preeclamptic pregnant women before and after deliveryQ73258662
Synergistic interaction between thromboxane A2 and mildly oxidized low density lipoproteins on vascular smooth muscle cell proliferationQ73334865
Pregnancy-associated reduction in vascular protein kinase C activity rebounds during inhibition of NO synthesisQ73426782
P433issue4
P921main subjectmaternal healthQ6786626
pre-eclampsiaQ61335
P304page(s)204-226
P577publication date2010-10-01
P1433published inCardiovascular & hematological agents in medicinal chemistryQ27721058
P1476titleMolecular and vascular targets in the pathogenesis and management of the hypertension associated with preeclampsia
P478volume8

Reverse relations

cites work (P2860)
Q35813964A Proposed Molecular Mechanism of High-Dose Vitamin D3 Supplementation in Prevention and Treatment of Preeclampsia.
Q33665037Altered matrix metalloproteinase-2 and -9 expression/activity links placental ischemia and anti-angiogenic sFlt-1 to uteroplacental and vascular remodeling and collagen deposition in hypertensive pregnancy
Q28083815Bioactive factors in uteroplacental and systemic circulation link placental ischemia to generalized vascular dysfunction in hypertensive pregnancy and preeclampsia
Q46317860Correlations between circulating levels of adipokines and anti-angiogenic factors in women with BMI <30 and a late-onset preeclampsia
Q51000408Decreased homodimerization and increased TIMP-1 complexation of uteroplacental and uterine arterial matrix metalloproteinase-9 during hypertension-in-pregnancy.
Q37318884Enhanced endothelin receptor type B-mediated vasodilation and underlying [Ca²⁺]i in mesenteric microvessels of pregnant rats
Q36340302Epicardial fat tissue thickness in preeclamptic and normal pregnancies
Q38640174Functional IGF1R variant predicts breast cancer risk in women with preeclampsia in California Teachers Study
Q45879845Hemodynamic correlates of low umbilical cord vitamin D and ionized calcium
Q36793344Immunomodulatory role of vitamin D in the pathogenesis of preeclampsia
Q38720237Increased vascular and uteroplacental matrix metalloproteinase-1 and -7 levels and collagen type I deposition in hypertension in pregnancy: role of TNF-α.
Q96431729Independent influences of maternal obesity and fetal sex on maternal cardiovascular adaptation to pregnancy: a prospective cohort study
Q37686924Involvement of miRNAs in placental alterations mediated by oxidative stress.
Q50597564Is the level of maternal serum prohepcidin associated with preeclampsia?
Q35956397Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy
Q37194320Maternal plasma miRNAs expression in preeclamptic pregnancies
Q46342648Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia
Q47223491Matrix Metalloproteinases, Vascular Remodeling, and Vascular Disease
Q37136212Mechanisms of Endothelial Dysfunction in Hypertensive Pregnancy and Preeclampsia
Q58589187Molecular Determinants of Microvascular Dysfunction in Hypertensive Pregnancy and Preeclampsia
Q93156154Molecular Targets of Aspirin and Prevention of Preeclampsia and Their Potential Association with Circulating Extracellular Vesicles during Pregnancy
Q36105461Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn
Q38804461PTH and Vitamin D.
Q42716832Pro-inflammatory role of angiotensin II in mercuric chloride-induced nephropathy in rats
Q26828020Role of endothelin in uteroplacental circulation and fetal vascular function
Q36984404The effect of allopurinol on lowering blood pressure in hemodialysis patients with hyperuricemia
Q28392215The effects of oxidative stress on female reproduction: a review
Q47645647The prediction of fetal death with a simple maternal blood test at 20-24 weeks: a role for angiogenic index-1 (PlGF/sVEGFR-1 ratio).
Q37651300The relationship of a family history for hypertension, myocardial infarction, or stroke with cardiovascular physiology in young women
Q37699594The risk factors for failure of labor induction: a cohort study.
Q35751236The role of cytokines as inflammatory mediators in preeclampsia
Q39039141Tumor Necrosis Factor-Alpha and Pregnancy: Focus on Biologics. An Updated and Comprehensive Review
Q51339686Uteroplacental insufficiency programmes vascular dysfunction in non-pregnant rats: compensatory adaptations in pregnancy.
Q47103299Vitamin D Enhances Efficacy of Oral Nifedipine in Treating Preeclampsia with Severe Features: A Double Blinded, Placebo-Controlled and Randomized Clinical Trial
Q46322246Vitamin D receptor polymorphisms in hypertensive disorders of pregnancy

Search more.