Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signaling

scientific article published on 7 February 2008

Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/HYPERTENSIONAHA.107.097790
P8608Fatcat IDrelease_gx3zdcurkbdljktjn4paoof6c4
P932PMC publication ID3261612
P698PubMed publication ID18259044

P50authorSusan M. RaminQ110252023
Shakil AhmadQ43177725
P2093author name stringAsif Ahmed
Yang Xia
Tiejuan Mi
Rodney E Kellems
Mary-Clare Day
Shahrzad Abbasi
Cissy Chenyi Zhou
Lingwei Xia
P2860cites workHuman cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?Q24561702
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Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in miceQ28504776
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
Plasma active renin, angiotensin I, and angiotensin II during pregnancy and in preeclampsiaQ74195115
A pressor substance (hysterotonin) occurring in toxemiaQ78778797
Overexpression of the soluble vascular endothelial growth factor receptor in preeclamptic patients: pathophysiological consequencesQ79260245
Circulating levels of the antiangiogenic marker sFLT-1 are increased in first versus second pregnanciesQ80379702
Antiangiogenic effect of soluble vascular endothelial growth factor receptor-1 in placental angiogenesisQ80410160
Angiotensin II type 1 receptor agonistic antibodies reflect fundamental alterations in the uteroplacental vasculatureQ81423834
Plasma renin, renin substrate, angiotensin II, and aldosterone in hypertensive disease of pregnancyQ93732540
Regulation of placental vascular endothelial growth factor (VEGF) and placenta growth factor (PIGF) and soluble Flt-1 by oxygen--a review.Q33930029
Pre-eclampsiaQ34079933
A study of angiotensin II pressor response throughout primigravid pregnancyQ34512573
Pathophysiology of preeclampsia: linking placental ischemia/hypoxia with microvascular dysfunction.Q34702420
The myometrial junctional zone spiral arteries in normal and abnormal pregnancies: a review of the literatureQ35002391
Potential roles of angiotensin receptor-activating autoantibody in the pathophysiology of preeclampsiaQ35681821
Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancyQ35699115
Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndromeQ35750283
Localization of the angiotensin II and its receptor subtype expression in human endometrium and identification of a novel high-affinity angiotensin II binding siteQ35752519
Role of the renin-angiotensin system in the pathogenesis of preeclampsiaQ36064478
Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restrictionQ36228832
The renin-angiotensin-aldosterone system in preeclampsia. A reviewQ36453940
Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome?Q37366512
Cellular localization of AT1 receptor mRNA and protein in normal placenta and its reduced expression in intrauterine growth restriction. Angiotensin II stimulates the release of vasorelaxantsQ37377636
Angiotensin II levels in hypertensive and normotensive pregnanciesQ37664263
Toxemia: new concepts in an old diseaseQ39559348
Cytotrophoblasts up-regulate soluble fms-like tyrosine kinase-1 expression under reduced oxygen: an implication for the placental vascular development and the pathophysiology of preeclampsiaQ40530224
Angiotensin II inhibits human trophoblast invasion through AT1 receptor activationQ40735093
IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1.Q40934953
Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia.Q41091104
Catecholamines. Their role in pregnancy and the development of pregnancy-induced hypertensionQ41109219
Colocalisation of vascular endothelial growth factor and its Flt-1 receptor in human placentaQ41385756
Placental cytokines and the pathogenesis of preeclampsiaQ41452017
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cellsQ44320558
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidaseQ44385661
Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activationQ45069619
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human mesangial cells and induce interleukin-6 and plasminogen activator inhibitor-1 secretionQ46344658
Circulating angiogenic factors and the risk of preeclampsiaQ47217679
Endothelial dysfunction in preeclampsiaQ47879591
Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsiaQ47915288
Evidence supporting a role for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia. Young Investigator AwardQ48348609
Negative regulation of soluble Flt-1 and soluble endoglin release by heme oxygenase-1.Q51037240
Raised serum TNF-alpha, blood sugar and uric acid in preeclampsia in third trimester of pregnancy.Q51501322
Relation between circulating angiotensin II type 1 receptor agonistic autoantibodies and soluble fms-like tyrosine kinase 1 in the pathogenesis of preeclampsia.Q52933863
Elevated Serum Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR-1) Levels in Women with PreeclampsiaQ56619500
Dysregulation of the Circulating and Tissue-Based Renin-Angiotensin System in PreeclampsiaQ56981959
Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1Q57105968
Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsiaQ58778301
Platelet angiotensin II binding and plasma renin concentration, plasma renin substrate and plasma angiotensin II in human pregnancyQ59368198
A Vascular Endothelial Growth Factor Antagonist Is Produced by the Human Placenta and Released into the Maternal Circulation1Q61479346
Renin, angiotensin II, aldosterone, catecholamines, prostaglandins and vasopressin. The importance of pressor and depressor factors for hypertension in pregnancyQ70391984
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectpre-eclampsiaQ61335
autoantibodyQ785022
maternal healthQ6786626
P304page(s)1010-1019
P577publication date2008-02-07
P1433published inHypertensionQ5958695
P1476titleAutoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signaling
P478volume51

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