AT1-AA (Angiotensin II Type 1 Receptor Agonistic Autoantibody) Blockade Prevents Preeclamptic Symptoms in Placental Ischemic Rats.

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AT1-AA (Angiotensin II Type 1 Receptor Agonistic Autoantibody) Blockade Prevents Preeclamptic Symptoms in Placental Ischemic Rats. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/HYPERTENSIONAHA.117.10681
P932PMC publication ID5903585
P698PubMed publication ID29555668

P2093author name stringBabbette LaMarca
Denise C Cornelius
Mark W Cunningham
Jan M Williams
Lorena Amaral
Nathan Usry
Javier Castillo
Nathan Campbell
Tarek Ibrahim
Venkata Ramana Vaka
P2860cites workPreeclampsia: long-term consequences for vascular healthQ26800272
Angiotensin receptor agonistic autoantibodies and hypertension: preeclampsia and beyondQ27027039
Bioactive factors in uteroplacental and systemic circulation link placental ischemia to generalized vascular dysfunction in hypertensive pregnancy and preeclampsiaQ28083815
Role of endothelin in cardiovascular diseaseQ28216230
Role of endothelin in mediating soluble fms-like tyrosine kinase 1-induced hypertension in pregnant ratsQ28571017
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Transcutaneous measurement of glomerular filtration rate using FITC-sinistrin in ratsQ33450193
Angiotensin receptor agonistic autoantibody is highly prevalent in preeclampsia: correlation with disease severityQ33748680
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
Agonistic Autoantibodies to the Angiotensin II Type 1 Receptor Enhance Angiotensin II-Induced Renal Vascular Sensitivity and Reduce Renal Function During PregnancyQ34541831
Endothelin type A receptor antagonist attenuates placental ischemia-induced hypertension and uterine vascular resistanceQ34772464
Hypertension in response to placental ischemia during pregnancy: role of B lymphocytesQ35029700
Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signalingQ35681804
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant miceQ35701236
L-arginine supplementation abolishes the blood pressure and endothelin response to chronic increases in plasma sFlt-1 in pregnant ratsQ35950303
Activating autoantibodies to the angiotensin II type I receptor play an important role in mediating hypertension in response to adoptive transfer of CD4+ T lymphocytes from placental ischemic ratsQ35994304
A model of preeclampsia in rats: the reduced uterine perfusion pressure (RUPP) modelQ36115311
IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancyQ36178540
The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancyQ36407259
Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant ratsQ36683260
Identifying immune mechanisms mediating the hypertension during preeclampsiaQ37139722
Endothelial dysfunction. An important mediator in the pathophysiology of hypertension during pre-eclampsiaQ37229246
Angiotensin II type 1 receptor autoantibody (AT1-AA)-mediated pregnancy hypertensionQ37353499
Endothelin-1, oxidative stress, and endogenous angiotensin II: mechanisms of angiotensin II type I receptor autoantibody-enhanced renal and blood pressure response during pregnancyQ37353537
Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1.Q37447371
Placental Ischemia and Resultant Phenotype in Animal Models of PreeclampsiaQ37451544
The Endothelin Type A Receptor as a Potential Therapeutic Target in PreeclampsiaQ37729072
Cardiovascular disease risk in women with pre-eclampsia: systematic review and meta-analysisQ38080492
Natural killer cells in placentation and cancer: Implications for hypertension during pregnancyQ38742935
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cellsQ44320558
Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activationQ45069619
Serelaxin improves the pathophysiology of placental ischemia in the reduced uterine perfusion pressure rat model of preeclampsiaQ45350029
Angiotensin II receptor type 1 autoantibodies promote endothelial microparticles formation through activating p38 MAPK pathwayQ46922047
Natural killer cells mediate pathophysiology in response to reduced uterine perfusion pressureQ47637232
Gender-specific effect of overexpression of sFlt-1 in pregnant mice on fetal programming of blood pressure in the offspring later in life.Q51734953
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
Novel monoclonal antibodies against membrane structures that are preferentially expressed on IL-2-activated rat NK cellsQ74191520
Angiotensin II type 1 receptor agonistic antibodies reflect fundamental alterations in the uteroplacental vasculatureQ81423834
Changes in cardiac structure and function in rats immunized by angiotensin type 1 receptor peptidesQ82259476
Hypertension in response to AT1-AA: role of reactive oxygen species in pregnancy-induced hypertensionQ83799951
Angiotensin II type I receptor agonistic autoantibody-induced apoptosis in neonatal rat cardiomyocytes is dependent on the generation of tumor necrosis factor-αQ95445011
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectautoantibodyQ785022
P304page(s)886-893
P577publication date2018-03-19
P1433published inHypertensionQ5958695
P1476titleAT1-AA (Angiotensin II Type 1 Receptor Agonistic Autoantibody) Blockade Prevents Preeclamptic Symptoms in Placental Ischemic Rats.
P478volume71

Reverse relations

cites work (P2860)
Q99709814Acute kidney injury during pregnancy leads to increased sFlt-1 and sEng and decreased renal T regulatory cells in pregnant rats with HELLP syndrome
Q93109012Disturbed Cardiorespiratory Adaptation in Preeclampsia: Return to Normal Stress Regulation Shortly after Delivery?
Q90106114Letter to the Editor: Importance of B cells in response to placental ischemia
Q90259719Placental Origins of Preeclampsia: Potential Therapeutic Targets
Q104137018Preeclampsia: Linking Placental Ischemia with Maternal Endothelial and Vascular Dysfunction
Q92071252Renal natural killer cell activation and mitochondrial oxidative stress; new mechanisms in AT1-AA mediated hypertensive pregnancy
Q92572681miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia

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