Angiotensin II type 1 receptor autoantibody (AT1-AA)-mediated pregnancy hypertension

scientific article published on 28 December 2012

Angiotensin II type 1 receptor autoantibody (AT1-AA)-mediated pregnancy hypertension is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1111/AJI.12072
P932PMC publication ID3845346
P698PubMed publication ID23279165

P50authorFlorian HerseQ47804678
P2093author name stringBabbette LaMarca
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Angiotensin receptor agonistic autoantibody-mediated tumor necrosis factor-alpha induction contributes to increased soluble endoglin production in preeclampsiaQ33748650
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Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
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A study of angiotensin II pressor response throughout primigravid pregnancyQ34512573
Recent Insights into the pathogenesis of pre-eclampsiaQ34682287
Hypertension in response to placental ischemia during pregnancy: role of B lymphocytesQ35029700
Pre-eclampsia, the placenta and the maternal systemic inflammatory response--a reviewQ35169648
Angiotensin II type 1 autoantibody induced hypertension during pregnancy is associated with renal endothelial dysfunctionQ35576417
Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signalingQ35681804
Potential roles of angiotensin receptor-activating autoantibody in the pathophysiology of preeclampsiaQ35681821
Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancyQ35699115
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant miceQ35701236
Invasive cytotrophoblasts manifest evidence of oxidative stress in preeclampsiaQ35793389
Activating autoantibodies to the angiotensin II type I receptor play an important role in mediating hypertension in response to adoptive transfer of CD4+ T lymphocytes from placental ischemic ratsQ35994304
Preeclampsia: recent insightsQ36288757
The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancyQ36407259
The role of RAS in the pathogenesis of preeclampsiaQ36467563
Thyrotropin-blocking autoantibodies and thyroid-stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versaQ36515453
Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant ratsQ36683260
Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant ratsQ37436219
Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1.Q37447371
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Candesartan versus imidapril in hypertension: a randomised study to assess effects of anti-AT1 receptor autoantibodiesQ38494999
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Hypertensive disorders in pregnancyQ43530362
Placental superoxide is increased in pre-eclampsiaQ43564655
Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide.Q43576536
Hypoxia favours necrotic versus apoptotic shedding of placental syncytiotrophoblast into the maternal circulationQ44302005
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cellsQ44320558
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidaseQ44385661
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejectionQ45259438
Teratogenicity with angiotensin II receptor antagonists in pregnancyQ46948262
Circulating angiogenic factors and the risk of preeclampsiaQ47217679
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of tumor necrosis factor-alpha.Q51359651
Involvement of functional autoantibodies against vascular receptors in systemic sclerosis.Q52900457
Relation between circulating angiotensin II type 1 receptor agonistic autoantibodies and soluble fms-like tyrosine kinase 1 in the pathogenesis of preeclampsia.Q52933863
Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia.Q52940276
Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia.Q54570213
Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats.Q54661322
Trophoblasts Reduce the Vascular Smooth Muscle Cell Proatherogenic ResponseQ56981910
Agonistic Angiotensin II Type 1 Receptor Autoantibodies in Postpartum Women With a History of PreeclampsiaQ56981931
CD19 + CD5 + Cells as Indicators of PreeclampsiaQ59906564
Fetal and neonatal consequences of antenatal exposure to type 1 angiotensin II receptor-antagonistsQ61943646
Epidemiology of preeclampsia and eclampsia in the United States, 1979-1986Q64128968
A prospective, controlled multicenter study on the obstetric risks of pregnant women with antiphospholipid antibodiesQ67586423
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
Autoantibodies against the angiotensin receptor (AT1) in patients with hypertensionQ74126541
Definitive molecular evidence of renin-angiotensin system in human uterine decidual cellsQ74188076
Risk of congenital complete heart block in newborns of mothers with anti-Ro/SSA antibodies detected by counterimmunoelectrophoresis: a prospective study of 100 womenQ74384559
Explaining and predicting preeclampsiaQ80223255
Agonistic autoantibodies and rejection of renal allograftsQ81386151
Angiotensin II type 1 receptor agonistic antibodies reflect fundamental alterations in the uteroplacental vasculatureQ81423834
Foetal kidney maldevelopment in maternal use of angiotensin II type I receptor antagonistsQ82975650
Activation of the complement system in normal pregnancy and preeclampsiaQ83021096
Decreased expression of complement 3a receptor (C3aR) in human placentas from severe preeclamptic pregnanciesQ84819984
P433issue4
P921main subjectarterial hypertensionQ41861
autoantibodyQ785022
maternal healthQ6786626
P304page(s)413-418
P577publication date2012-12-28
P1433published inAmerican Journal of Reproductive ImmunologyQ15761228
P1476titleAngiotensin II type 1 receptor autoantibody (AT1-AA)-mediated pregnancy hypertension
P478volume69

Reverse relations

cites work (P2860)
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Q33789436B cells: the old new players in reproductive immunology
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Q57150158The role of Agonistic Autoantibodies to the Angiotensin II Type 1 Receptor (AT1-AA) in Pathophysiology of Preeclampsia
Q33834419The role of inflammation in the pathology of preeclampsia
Q26994764The treatment of hypertension during pregnancy: when should blood pressure medications be started?
Q51294484Vitamin D supplementation reduces some AT1-AA-induced downstream targets implicated in preeclampsia including hypertension.

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