Agonistic Autoantibodies to the Angiotensin II Type 1 Receptor Enhance Angiotensin II-Induced Renal Vascular Sensitivity and Reduce Renal Function During Pregnancy

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Agonistic Autoantibodies to the Angiotensin II Type 1 Receptor Enhance Angiotensin II-Induced Renal Vascular Sensitivity and Reduce Renal Function During Pregnancy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/HYPERTENSIONAHA.116.07971
P932PMC publication ID5142826
P698PubMed publication ID27698062

P50authorBabbette LaMarcaQ88459247
Gerd WallukatQ63288594
Ralf DechendQ63812628
P2093author name stringMark W Cunningham
Jan M Williams
Lorena Amaral
Nathan Usry
P2860cites workPreeclampsia: long-term consequences for vascular healthQ26800272
Angiotensin receptor agonistic autoantibodies and hypertension: preeclampsia and beyondQ27027039
Nitric oxide and reactive oxygen species in the pathogenesis of preeclampsiaQ28083676
What we have learned about preeclampsiaQ28196892
Longitudinal study of the renin-angiotensin-aldosterone system in hypertensive pregnant women: deviations related to the development of superimposed preeclampsiaQ68432345
Does nitric oxide play a role in normal pregnancy and pregnancy-induced hypertension?Q72578476
Reduced sensitivity of the renal circulation to angiotensin II in pregnant ratsQ73762358
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
Renin-angiotensin-aldosterone system in pregnancy-induced hypertensionQ73896725
Abnormal expression of type 1 plasminogen activator inhibitor and tissue factor in severe preeclampsiaQ74527090
Pre-eclampsiaQ81446389
Changes in cardiac structure and function in rats immunized by angiotensin type 1 receptor peptidesQ82259476
Hypertension in response to AT1-AA: role of reactive oxygen species in pregnancy-induced hypertensionQ83799951
Angiotensin II type I receptor agonistic autoantibody-induced apoptosis in neonatal rat cardiomyocytes is dependent on the generation of tumor necrosis factor-αQ95445011
Renal redox response to normal pregnancy in the ratQ28395942
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
The role of inflammation in the pathology of preeclampsiaQ33834419
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptorQ33848380
Maternal glomerular filtration rate in pregnancy and fetal sizeQ33864460
Summary of the NHLBI Working Group on Research on Hypertension During PregnancyQ34182166
Preeclampsia from a renal point of view: Insides into disease models, biomarkers and therapyQ34453242
A study of angiotensin II pressor response throughout primigravid pregnancyQ34512573
AT1 receptor heterodimers and angiotensin II responsiveness in preeclampsiaQ35689550
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant miceQ35701236
Activating autoantibodies to the angiotensin II type I receptor play an important role in mediating hypertension in response to adoptive transfer of CD4+ T lymphocytes from placental ischemic ratsQ35994304
Activating auto-antibodies against the AT1 receptor in preeclampsiaQ36010629
Role of the renin-angiotensin system in the pathogenesis of preeclampsiaQ36064478
IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancyQ36178540
Agonistic antibodies directed at the angiotensin II, AT1 receptor in preeclampsiaQ36380482
The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancyQ36407259
Sodium-renin-aldosterone relations in normal and hypertensive pregnancyQ36429185
Renal function during normal pregnancy and preeclampsiaQ36664126
Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant ratsQ36683260
Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsiaQ37042332
Angiotensin II type 1 receptor autoantibody (AT1-AA)-mediated pregnancy hypertensionQ37353499
Endothelin-1, oxidative stress, and endogenous angiotensin II: mechanisms of angiotensin II type I receptor autoantibody-enhanced renal and blood pressure response during pregnancyQ37353537
Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1.Q37447371
Structural determinants for binding, activation, and functional selectivity of the angiotensin AT1 receptorQ38228306
Oxidative stress in pregnancy and fertility pathologiesQ38230280
Renal hemodynamics and tubular function normal human pregnancyQ40295235
A review of mutagenesis studies of angiotensin II type 1 receptor, the three-dimensional receptor model in search of the agonist and antagonist binding site and the hypothesis of a receptor activation mechanismQ41531265
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidaseQ44385661
Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activationQ45069619
Increased AT(1) receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsivenessQ46841539
Angiotensin II receptor type 1 autoantibodies promote endothelial microparticles formation through activating p38 MAPK pathwayQ46922047
Inflammatory cytokines, vascular function, and hypertensionQ47606320
Plasma volume and glomerular filtration rate in pregnancy and their relation to differences in fetal growth.Q47938222
Temporal relationships between hormonal and hemodynamic changes in early human pregnancy.Q54112770
Regulator of G protein signaling 5 is a determinant of gestational hypertension and preeclampsiaQ57254079
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectautoantibodyQ785022
P304page(s)1308-1313
P577publication date2016-10-03
P1433published inHypertensionQ5958695
P1476titleAgonistic Autoantibodies to the Angiotensin II Type 1 Receptor Enhance Angiotensin II-Induced Renal Vascular Sensitivity and Reduce Renal Function During Pregnancy
P478volume68

Reverse relations

cites work (P2860)
Q53700889AT1-AA (Angiotensin II Type 1 Receptor Agonistic Autoantibody) Blockade Prevents Preeclamptic Symptoms in Placental Ischemic Rats.
Q64255839Cardiovascular System in Preeclampsia and Beyond
Q96230486Increased AT2R expression is induced by AT1R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration
Q38707968Increased Angiotensin II Sensitivity Contributes to Microvascular Dysfunction in Women Who Have Had Preeclampsia
Q64115613Limited AT1 Receptor Internalization Is a Novel Mechanism Underlying Sustained Vasoconstriction Induced by AT1 Receptor Autoantibody From Preeclampsia
Q90434468Local angiotensin-(1-7) administration improves microvascular endothelial function in women who have had preeclampsia
Q57127734Lower circulating angiotensin II levels are related to the severity of preeclampsia and its risk as disclosed by a specific bioassay
Q92071252Renal natural killer cell activation and mitochondrial oxidative stress; new mechanisms in AT1-AA mediated hypertensive pregnancy
Q57167914Residual Vascular Dysfunction in Women with a History of Preeclampsia
Q91910507The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats
Q57150158The role of Agonistic Autoantibodies to the Angiotensin II Type 1 Receptor (AT1-AA) in Pathophysiology of Preeclampsia

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